OSEBX1,423.56+0.84%
EQNR284.60+4.20%
DNB198.35-1.15%
MOWI172.80+0.45%
Brent$71.24-0.32%
EUR/USD1.0824-0.14%
DXY104.18+0.08%
INDICATIVE · SAMPLE DATA
BCYC$4.6759

Bicycle Therapeutics PLC

Biotechnology & Medical ResearchVerified

Bicycle Therapeutics has a market capitalization of $326.02 million and a price-to-book ratio of 0.53, indicating that the company is trading at a discount relative to its book value. The company's liquidity position is characterized by a current ratio of 11.98, suggesting strong short-term liquidity, but it has a negative net cash position after subtracting total debt, which is a key liquidity flag. The company's capital structure is largely equity-based, with total equity of $609.98 million and total liabilities of $107.62 million, resulting in a debt-to-equity ratio of 0.0. In terms of profitability, Bicycle Therapeutics is currently unprofitable, with a net income of -$218.96 million and an operating income of -$247.07 million. The company's return on equity is -0.359 and return on assets is -0.3051, both of which are significantly below the industry median for biotechnology firms. The company's operating cash flow is negative at -$249.68 million, and its free cash flow is also negative at -$214.89 million, indicating that the company is not generating positive cash flows from operations. Bicycle Therapeutics does not disclose specific revenue segments or geographic exposure in the provided data, but the company's operations are likely concentrated in the United States and Europe, as is typical for biotechnology firms. The company's revenue for the latest period is $72.59 million, and there is no indication of significant geographic diversification in the financial snapshot. The company's growth trajectory is uncertain, as it is currently unprofitable and not generating positive cash flows. The company's capital expenditure is relatively low at -$2.35 million, suggesting that it is not heavily investing in new projects or infrastructure. Analysts have a mixed outlook on the company, with a mean price target of $12.30 and a median price target of $10.00, indicating a potential for significant upside but also a high degree of uncertainty. The company's risk profile is characterized by medium liquidity risk and low dilution risk. The key risk flag is the negative net cash position after subtracting total debt, which could impact the company's ability to fund operations and research and development activities. The company has a low dilution risk, with no near-term pressure for additional equity issuance, and the dilution potential is considered low. Recent events and filings do not provide specific details on the company's operations or strategic initiatives, but the company is likely focused on advancing its pipeline of bicyclic peptide-based therapeutics through clinical trials and regulatory approvals. The company's recent financial performance and analyst estimates suggest that it is in a development phase, with a focus on long-term growth rather than short-term profitability.

30-day price · BCYC(missing data)
No daily-bar history available from current data sources. Alternate source pending.
Profile
CompanyBicycle Therapeutics PLC
TickerBCYC.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical company focused on the discovery and development of bicyclic peptide-based therapeutics for the treatment of cancer and autoimmune diseases.

Classification. Bicycle Therapeutics is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

Bicycle Therapeutics has a market capitalization of $326.02 million and a price-to-book ratio of 0.53, indicating that the company is trading at a discount relative to its book value. The company's liquidity position is characterized by a current ratio of 11.98, suggesting strong short-term liquidity, but it has a negative net cash position after subtracting total debt, which is a key liquidity flag. The company's capital structure is largely equity-based, with total equity of $609.98 million and total liabilities of $107.62 million, resulting in a debt-to-equity ratio of 0.0. In terms of profitability, Bicycle Therapeutics is currently unprofitable, with a net income of -$218.96 million and an operating income of -$247.07 million. The company's return on equity is -0.359 and return on assets is -0.3051, both of which are significantly below the industry median for biotechnology firms. The company's operating cash flow is negative at -$249.68 million, and its free cash flow is also negative at -$214.89 million, indicating that the company is not generating positive cash flows from operations. Bicycle Therapeutics does not disclose specific revenue segments or geographic exposure in the provided data, but the company's operations are likely concentrated in the United States and Europe, as is typical for biotechnology firms. The company's revenue for the latest period is $72.59 million, and there is no indication of significant geographic diversification in the financial snapshot. The company's growth trajectory is uncertain, as it is currently unprofitable and not generating positive cash flows. The company's capital expenditure is relatively low at -$2.35 million, suggesting that it is not heavily investing in new projects or infrastructure. Analysts have a mixed outlook on the company, with a mean price target of $12.30 and a median price target of $10.00, indicating a potential for significant upside but also a high degree of uncertainty. The company's risk profile is characterized by medium liquidity risk and low dilution risk. The key risk flag is the negative net cash position after subtracting total debt, which could impact the company's ability to fund operations and research and development activities. The company has a low dilution risk, with no near-term pressure for additional equity issuance, and the dilution potential is considered low. Recent events and filings do not provide specific details on the company's operations or strategic initiatives, but the company is likely focused on advancing its pipeline of bicyclic peptide-based therapeutics through clinical trials and regulatory approvals. The company's recent financial performance and analyst estimates suggest that it is in a development phase, with a focus on long-term growth rather than short-term profitability.
Key takeaways
  • Bicycle Therapeutics is a clinical-stage biopharmaceutical company with a focus on developing bicyclic peptide-based therapeutics for cancer and autoimmune diseases.
  • The company is currently unprofitable, with significant negative net income and operating income, and is not generating positive cash flows from operations.
  • The company's liquidity position is strong in the short term, as indicated by a high current ratio, but it has a negative net cash position after subtracting total debt.
  • Analysts have a mixed outlook on the company, with a mean price target of $12.30 and a median price target of $10.00, indicating potential for significant upside but also a high degree of uncertainty.
  • # RATIONALES
  • margin_outlook_rationale: The company's margin outlook is negative due to its current unprofitability and significant negative net income.
  • rd_outlook_rationale: The company's R&D outlook is uncertain, as it is in a development phase and not generating positive cash flows from operations.
  • capex_outlook_rationale: The company's capex outlook is low, as indicated by its relatively low capital expenditure.
Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$72.6M
Gross profit
Operating income-$247.1M
Net income-$219.0M
R&D
SG&A
D&A
SBC
Operating cash flow-$249.7M
CapEx-$2.4M
Free cash flow-$214.9M
Total assets$717.6M
Total liabilities$107.6M
Total equity$610.0M
Cash & equivalents
Long-term debt$874.0k
Valuation
Market price$4.67
Market cap$326.0M
Enterprise value$326.9M
P/E
Reported non-GAAP P/E
EV/Revenue4.5
EV/Op income
EV/OCF
P/B0.5
P/Tangible book0.5
Tangible book$610.0M
Net cash-$874.0k
Current ratio12.0
Debt/Equity0.0
ROA-30.5%
ROE-35.9%
Cash conversion1.1%
CapEx/Revenue-3.2%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskMedium
  • Net cash is negative after subtracting total debt.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 693 companies
MetricBCYCActivity
Op margin-340.4%2.4% medp25 -91.8% · p75 12.5%bottom quartile
Net margin-301.7%1.2% medp25 -98.4% · p75 10.4%bottom quartile
Gross margin45.6% medp25 29.8% · p75 66.7%
CapEx / revenue-3.2%-5.2% medp25 -15.8% · p75 -1.7%above median
Debt / equity0.0%9.3% medp25 0.1% · p75 43.8%bottom quartile
Observations
IR observations
Mean price target12.30 USD
Median price target10.00 USD
High price target36.00 USD
Low price target5.00 USD
Mean recommendation2.08 (1=strong buy, 5=strong sell)
Strong-buy count4.00
Buy count4.00
Hold count5.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-2.29 USD
Last actual EPS-3.16 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod financials
no public URL
2026-05-16 15:44 UTC#86d8db25
Market quoteclose USD 5.15 · shares 0.07B diluted
no public URL
2026-05-16 15:46 UTC#2d515d88
Source: analysis-pipeline (hybrid)Generated: 2026-05-27 11:32 UTCJob: 06923d24