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INDICATIVE · SAMPLE DATA
MGNX$4.2460

MacroGenics Inc

Biotechnology & Medical ResearchVerified

MacroGenics Inc has a market capitalization of $269.5 million and a price-to-book ratio of 4.85, indicating that the market is valuing the company at a premium to its book value. The company's liquidity position is mixed, with $57.2 million in cash and equivalents but $70.0 million in long-term debt, resulting in a net cash position that is negative. The current ratio of 5.1 suggests that the company has sufficient current assets to cover its current liabilities, but the negative operating cash flow of -$81.0 million and free cash flow of -$69.4 million indicate ongoing cash outflows from operations. In terms of profitability, MacroGenics Inc reported a net loss of $74.6 million and an operating loss of $72.8 million in the latest period, which is a significant deviation from the industry's median profitability metrics. The company's return on equity (ROE) is -1.34, and its return on assets (ROA) is -0.29, both of which are negative and suggest that the company is not generating returns that exceed its cost of capital. The gross profit margin is 76.0%, which is relatively high, but the operating margin is -48.7%, indicating that the company is incurring substantial operating expenses relative to its revenue. MacroGenics Inc's revenue is concentrated in a single business segment, as the company does not disclose multiple segments in its financial reporting. The company's geographic exposure is primarily in the United States, where it has its headquarters and where the majority of its clinical trials and commercial activities are conducted. There is no indication of significant international revenue concentration in the latest financial data. The company's growth trajectory is uncertain, as it has reported a net loss in the latest period and has not provided specific guidance for the next fiscal year. The company's capital expenditures were -$1.9 million, indicating a reduction in capital spending. The company's outlook for the current fiscal year is not explicitly stated, but the negative operating and net income suggest that the company is not on a clear path to profitability. The risk assessment for MacroGenics Inc indicates a medium liquidity risk and a low dilution risk. The company's debt-to-equity ratio is 1.26, which is relatively high, and the negative net cash position after subtracting total debt is a key flag. The company has not disclosed any recent dilutive events, and the dilution potential is considered low based on the current share count and financial position. Recent events for MacroGenics Inc include the continued development of its monoclonal antibody therapies, with a focus on advancing its pipeline through clinical trials. The company has not disclosed any recent regulatory filings or earnings call transcripts that would indicate significant changes in its business strategy or financial outlook. The company's price targets from analysts range from $4.00 to $9.00, with a mean of $6.00 and a median of $5.50, suggesting a generally positive but cautious outlook from the investment community.

30-day price · MGNX+1.06 (+30.5%)
Low$2.85High$4.64Close$4.53As of22 May, 00:00 UTC
Profile
CompanyMacroGenics Inc
TickerMGNX.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. MacroGenics Inc is a biotechnology company focused on the discovery, development, and commercialization of innovative monoclonal antibody therapies for the treatment of cancer and autoimmune diseases.

Classification. MacroGenics Inc is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

MacroGenics Inc has a market capitalization of $269.5 million and a price-to-book ratio of 4.85, indicating that the market is valuing the company at a premium to its book value. The company's liquidity position is mixed, with $57.2 million in cash and equivalents but $70.0 million in long-term debt, resulting in a net cash position that is negative. The current ratio of 5.1 suggests that the company has sufficient current assets to cover its current liabilities, but the negative operating cash flow of -$81.0 million and free cash flow of -$69.4 million indicate ongoing cash outflows from operations. In terms of profitability, MacroGenics Inc reported a net loss of $74.6 million and an operating loss of $72.8 million in the latest period, which is a significant deviation from the industry's median profitability metrics. The company's return on equity (ROE) is -1.34, and its return on assets (ROA) is -0.29, both of which are negative and suggest that the company is not generating returns that exceed its cost of capital. The gross profit margin is 76.0%, which is relatively high, but the operating margin is -48.7%, indicating that the company is incurring substantial operating expenses relative to its revenue. MacroGenics Inc's revenue is concentrated in a single business segment, as the company does not disclose multiple segments in its financial reporting. The company's geographic exposure is primarily in the United States, where it has its headquarters and where the majority of its clinical trials and commercial activities are conducted. There is no indication of significant international revenue concentration in the latest financial data. The company's growth trajectory is uncertain, as it has reported a net loss in the latest period and has not provided specific guidance for the next fiscal year. The company's capital expenditures were -$1.9 million, indicating a reduction in capital spending. The company's outlook for the current fiscal year is not explicitly stated, but the negative operating and net income suggest that the company is not on a clear path to profitability. The risk assessment for MacroGenics Inc indicates a medium liquidity risk and a low dilution risk. The company's debt-to-equity ratio is 1.26, which is relatively high, and the negative net cash position after subtracting total debt is a key flag. The company has not disclosed any recent dilutive events, and the dilution potential is considered low based on the current share count and financial position. Recent events for MacroGenics Inc include the continued development of its monoclonal antibody therapies, with a focus on advancing its pipeline through clinical trials. The company has not disclosed any recent regulatory filings or earnings call transcripts that would indicate significant changes in its business strategy or financial outlook. The company's price targets from analysts range from $4.00 to $9.00, with a mean of $6.00 and a median of $5.50, suggesting a generally positive but cautious outlook from the investment community.
Key takeaways
  • MacroGenics Inc is a biotechnology company with a focus on monoclonal antibody therapies for cancer and autoimmune diseases.
  • The company has a high price-to-book ratio of 4.85, indicating a premium valuation relative to its book value.
  • MacroGenics Inc reported a net loss of $74.6 million and an operating loss of $72.8 million, with negative returns on equity and assets.
  • The company's liquidity position is mixed, with a current ratio of 5.1 but negative operating and free cash flows.
  • The company's risk assessment indicates a medium liquidity risk and a low dilution risk.
  • Analysts have provided a range of price targets from $4.00 to $9.00, with a mean of $6.00 and a median of $5.50.
  • --
  • # RATIONALES
Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$149.5M
Gross profit$113.5M
Operating income-$72.8M
Net income-$74.6M
R&D
SG&A
D&A
SBC
Operating cash flow-$81.0M
CapEx-$1.9M
Free cash flow-$69.4M
Total assets$256.8M
Total liabilities$201.3M
Total equity$55.6M
Cash & equivalents$57.2M
Long-term debt$70.0M
Valuation
Market price$4.24
Market cap$269.5M
Enterprise value$282.3M
P/E
Reported non-GAAP P/E
EV/Revenue1.9
EV/Op income
EV/OCF
P/B4.8
P/Tangible book4.8
Tangible book$55.6M
Net cash-$12.8M
Current ratio5.1
Debt/Equity1.3
ROA-29.0%
ROE-1.3%
Cash conversion1.1%
CapEx/Revenue-1.3%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskMedium
  • Net cash is negative after subtracting total debt.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 693 companies
MetricMGNXActivity
Op margin-48.7%2.4% medp25 -91.8% · p75 12.5%below median
Net margin-49.9%1.2% medp25 -98.4% · p75 10.4%below median
Gross margin75.9%45.6% medp25 29.8% · p75 66.7%top quartile
CapEx / revenue-1.3%-5.2% medp25 -15.8% · p75 -1.7%top quartile
Debt / equity126.0%9.3% medp25 0.1% · p75 43.8%top quartile
Observations
IR observations
Mean price target6.00 USD
Median price target5.50 USD
High price target9.00 USD
Low price target4.00 USD
Mean recommendation2.43 (1=strong buy, 5=strong sell)
Strong-buy count1.00
Buy count2.00
Hold count4.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-1.71 USD
Last actual EPS-1.18 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod financials
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2026-05-23 10:30 UTC#b3c7c25a
Source: analysis-pipeline (hybrid)Generated: 2026-05-28 13:48 UTCJob: b03f8199