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INDICATIVE · SAMPLE DATA
MGTX$9.7659

MeiraGTx Holdings PLC

Biotechnology & Medical ResearchVerified

MeiraGTx Holdings PLC has a negative net equity of -$5.79 million, indicating a significant deficit in its capital structure. The company's liquidity position is further strained by a current ratio of 0.75, suggesting that it may struggle to meet short-term obligations with its current assets. The liquidity_fpt metric indicates a cash and equivalents position of $65.93 million, but this is offset by long-term debt of $74.48 million, resulting in a net cash position that is negative after subtracting total debt. The company's profitability is challenged, with a net loss of $114.20 million and an operating loss of $105.97 million. The return on equity (ROE) is an unusually high 19.71%, which is misleading due to the negative equity base. The return on assets (ROA) is -0.47%, indicating that the company is not generating a return on its asset base. The gross profit margin is 93.99%, but this is not translating into operating or net profitability. MeiraGTx operates as a single business segment, with all revenue derived from its core biotechnology activities. The company does not disclose geographic revenue breakdowns, but its operations are primarily based in the United States and the United Kingdom. The lack of geographic diversification may expose the company to regional economic and regulatory risks. The company's growth trajectory is uncertain, with a revenue of $81.39 million in the latest period. The outlook for the current fiscal year is not provided, but the company's operating cash flow of -$46.36 million and free cash flow of -$105.42 million suggest that it is not generating sufficient cash to fund operations or growth. The capital expenditure of -$3.83 million indicates that the company is not investing in new assets, which may limit its long-term growth potential. The risk assessment highlights medium liquidity risk and low dilution risk. The company's net cash position is negative after subtracting total debt, which could lead to liquidity constraints. The dilution risk is low, as the company has not issued additional shares recently, and the number of diluted shares is the same as the basic shares outstanding. The company's valuation is supported by a mean price target of $26.88, with a median of $23.50, indicating that analysts have a generally positive outlook despite the company's current financial challenges. Recent events include the company's continued focus on its pipeline of cell and gene therapies, with ongoing clinical trials in ophthalmology and oncology. The company has also been working on partnerships and collaborations to advance its product candidates. However, the company has not disclosed any recent significant events or filings that would indicate a change in its strategic direction or financial position.

30-day price · MGTX-0.39 (-4.0%)
Low$8.75High$11.85Close$9.24As of22 May, 00:00 UTC
Profile
CompanyMeiraGTx Holdings PLC
TickerMGTX.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. MeiraGTx Holdings PLC is a biotechnology company focused on the development and commercialization of cell and gene therapies, primarily in the ophthalmology and oncology fields.

Classification. The company is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

MeiraGTx Holdings PLC has a negative net equity of -$5.79 million, indicating a significant deficit in its capital structure. The company's liquidity position is further strained by a current ratio of 0.75, suggesting that it may struggle to meet short-term obligations with its current assets. The liquidity_fpt metric indicates a cash and equivalents position of $65.93 million, but this is offset by long-term debt of $74.48 million, resulting in a net cash position that is negative after subtracting total debt. The company's profitability is challenged, with a net loss of $114.20 million and an operating loss of $105.97 million. The return on equity (ROE) is an unusually high 19.71%, which is misleading due to the negative equity base. The return on assets (ROA) is -0.47%, indicating that the company is not generating a return on its asset base. The gross profit margin is 93.99%, but this is not translating into operating or net profitability. MeiraGTx operates as a single business segment, with all revenue derived from its core biotechnology activities. The company does not disclose geographic revenue breakdowns, but its operations are primarily based in the United States and the United Kingdom. The lack of geographic diversification may expose the company to regional economic and regulatory risks. The company's growth trajectory is uncertain, with a revenue of $81.39 million in the latest period. The outlook for the current fiscal year is not provided, but the company's operating cash flow of -$46.36 million and free cash flow of -$105.42 million suggest that it is not generating sufficient cash to fund operations or growth. The capital expenditure of -$3.83 million indicates that the company is not investing in new assets, which may limit its long-term growth potential. The risk assessment highlights medium liquidity risk and low dilution risk. The company's net cash position is negative after subtracting total debt, which could lead to liquidity constraints. The dilution risk is low, as the company has not issued additional shares recently, and the number of diluted shares is the same as the basic shares outstanding. The company's valuation is supported by a mean price target of $26.88, with a median of $23.50, indicating that analysts have a generally positive outlook despite the company's current financial challenges. Recent events include the company's continued focus on its pipeline of cell and gene therapies, with ongoing clinical trials in ophthalmology and oncology. The company has also been working on partnerships and collaborations to advance its product candidates. However, the company has not disclosed any recent significant events or filings that would indicate a change in its strategic direction or financial position.
Key takeaways
  • MeiraGTx Holdings PLC has a negative net equity and a current ratio below 1, indicating liquidity constraints.
  • The company's high gross profit margin is not translating into operating or net profitability.
  • The company operates as a single segment with no geographic diversification, exposing it to regional risks.
  • Analysts have a generally positive outlook, with a mean price target of $26.88, but the company's financial position remains challenging.
  • The company's liquidity risk is medium, and its dilution risk is low, with no recent share issuance.
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Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$81.4M
Gross profit$76.5M
Operating income-$106.0M
Net income-$114.2M
R&D
SG&A
D&A
SBC
Operating cash flow-$46.4M
CapEx-$3.8M
Free cash flow-$105.4M
Total assets$244.4M
Total liabilities$250.2M
Total equity-$5.8M
Cash & equivalents$65.9M
Long-term debt$74.5M
Valuation
Market price$9.76
Market cap$903.5M
Enterprise value$912.1M
P/E
Reported non-GAAP P/E
EV/Revenue11.2
EV/Op income
EV/OCF
P/B
P/Tangible book
Tangible book-$5.8M
Net cash-$8.6M
Current ratio0.8
Debt/Equity-12.9
ROA-46.7%
ROE19.7%
Cash conversion41.0%
CapEx/Revenue-4.7%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskMedium
  • Net cash is negative after subtracting total debt.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 693 companies
MetricMGTXActivity
Op margin-130.2%2.4% medp25 -91.8% · p75 12.5%bottom quartile
Net margin-140.3%1.2% medp25 -98.4% · p75 10.4%bottom quartile
Gross margin94.0%45.6% medp25 29.8% · p75 66.7%top quartile
CapEx / revenue-4.7%-5.2% medp25 -15.8% · p75 -1.7%above median
Debt / equity-1286.0%9.3% medp25 0.1% · p75 43.8%bottom quartile
Observations
IR observations
Mean price target26.88 USD
Median price target23.50 USD
High price target50.00 USD
Low price target16.00 USD
Mean recommendation1.75 (1=strong buy, 5=strong sell)
Strong-buy count2.00
Buy count6.00
Hold count0.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-1.64 USD
Last actual EPS-1.42 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod financials
no public URL
2026-05-22 11:30 UTC#77bf2edd
Source: analysis-pipeline (hybrid)Generated: 2026-05-28 13:51 UTCJob: e50f766c