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INDICATIVE · SAMPLE DATA
PRLD$4.6758

Prelude Therapeutics Inc

Biotechnology & Medical ResearchVerified

Prelude Therapeutics operates with a market capitalization of $371.5 million and a price-to-book ratio of 5.41, indicating a premium valuation relative to its book value. The company holds $35.3 million in cash and equivalents, while its total liabilities amount to $72.7 million, resulting in a debt-to-equity ratio of 0.0, suggesting a debt-free capital structure. The current ratio of 1.99 indicates the company has sufficient current assets to cover its current liabilities. The company reported a net loss of $99.5 million for the period, with an operating loss of $104.6 million. Return on equity (ROE) is negative at -14.5%, and return on assets (ROA) is also negative at -7.04%, reflecting poor profitability. The company's EBITDA multiple is negative at -3.22, and its enterprise value to revenue ratio is 27.7, both of which are unfavorable compared to industry norms. Prelude Therapeutics does not disclose segment-specific revenue data, but its geographic exposure is not detailed in the available financials. The company's revenue for the period was $12.14 million, indicating a small revenue base with no clear geographic diversification. The company's growth trajectory is uncertain, with no clear revenue growth or decline indicated in the available data. The company's operating cash flow is negative at -$56.3 million, and its free cash flow is -$97.9 million, indicating significant cash burn. The capital expenditure of -$67,000 is minimal, suggesting limited investment in physical assets. The company's risk profile is characterized by low liquidity and low dilution risk. No immediate filing-based liquidity or dilution flags were detected. The company's dilution potential is low, and no adjustments were applied to the valuation metrics. Recent events include analyst estimates indicating a mean price target of $6.17 and a median price target of $6.00, with a mean recommendation of 1.67 (1=strong buy, 5=strong sell). There is one strong-buy recommendation, two buy recommendations, and no hold recommendations.

30-day price · PRLD(missing data)
No daily-bar history available from current data sources. Alternate source pending.
Profile
CompanyPrelude Therapeutics Inc
TickerPRLD.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Prelude Therapeutics Inc is a biotechnology company focused on the development of novel therapeutics for the treatment of cancer, primarily through its proprietary drug delivery platform.

Classification. Prelude Therapeutics is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

Prelude Therapeutics operates with a market capitalization of $371.5 million and a price-to-book ratio of 5.41, indicating a premium valuation relative to its book value. The company holds $35.3 million in cash and equivalents, while its total liabilities amount to $72.7 million, resulting in a debt-to-equity ratio of 0.0, suggesting a debt-free capital structure. The current ratio of 1.99 indicates the company has sufficient current assets to cover its current liabilities. The company reported a net loss of $99.5 million for the period, with an operating loss of $104.6 million. Return on equity (ROE) is negative at -14.5%, and return on assets (ROA) is also negative at -7.04%, reflecting poor profitability. The company's EBITDA multiple is negative at -3.22, and its enterprise value to revenue ratio is 27.7, both of which are unfavorable compared to industry norms. Prelude Therapeutics does not disclose segment-specific revenue data, but its geographic exposure is not detailed in the available financials. The company's revenue for the period was $12.14 million, indicating a small revenue base with no clear geographic diversification. The company's growth trajectory is uncertain, with no clear revenue growth or decline indicated in the available data. The company's operating cash flow is negative at -$56.3 million, and its free cash flow is -$97.9 million, indicating significant cash burn. The capital expenditure of -$67,000 is minimal, suggesting limited investment in physical assets. The company's risk profile is characterized by low liquidity and low dilution risk. No immediate filing-based liquidity or dilution flags were detected. The company's dilution potential is low, and no adjustments were applied to the valuation metrics. Recent events include analyst estimates indicating a mean price target of $6.17 and a median price target of $6.00, with a mean recommendation of 1.67 (1=strong buy, 5=strong sell). There is one strong-buy recommendation, two buy recommendations, and no hold recommendations.
Key takeaways
  • Prelude Therapeutics is a biotechnology company with a focus on cancer therapeutics, operating in a high-growth but capital-intensive industry.
  • The company is currently unprofitable, with significant operating and net losses, and a negative return on equity and assets.
  • The company has a debt-free capital structure and a strong current ratio, but its cash burn is substantial, with negative operating and free cash flows.
  • Analysts have a generally positive outlook, with a mean price target above the current market price, but the company's financial performance remains a concern.
  • The company's lack of segment and geographic diversification data limits the ability to assess risk exposure comprehensively.
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  • ## RATIONALES
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Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$12.1M
Gross profit
Operating income-$104.6M
Net income-$99.5M
R&D
SG&A
D&A
SBC
Operating cash flow-$56.3M
CapEx-$67.0k
Free cash flow-$97.9M
Total assets$141.3M
Total liabilities$72.7M
Total equity$68.6M
Cash & equivalents$35.3M
Long-term debt$0.00
Valuation
Market price$4.67
Market cap$371.5M
Enterprise value$336.3M
P/E
Reported non-GAAP P/E
EV/Revenue27.7
EV/Op income
EV/OCF
P/B5.4
P/Tangible book5.4
Tangible book$68.6M
Net cash$35.3M
Current ratio2.0
Debt/Equity0.0
ROA-70.4%
ROE-1.4%
Cash conversion57.0%
CapEx/Revenue-0.5%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Healthcare Diagnostics · cohort 170 companies
MetricPRLDActivity
Op margin-861.3%-227.5% medp25 -1250.6% · p75 -3.5%below median
Net margin-819.6%-194.5% medp25 -1233.8% · p75 0.8%below median
Gross margin53.0% medp25 25.9% · p75 75.7%
CapEx / revenue-0.5%-8.2% medp25 -35.2% · p75 -2.5%top quartile
Debt / equity0.0%1.2% medp25 0.0% · p75 17.4%bottom quartile
Observations
IR observations
Mean price target6.17 Unknown error in universe processing
Median price target6.00 Unknown error in universe processing
High price target8.00 Unknown error in universe processing
Low price target4.50 Unknown error in universe processing
Mean recommendation1.67 (1=strong buy, 5=strong sell)
Strong-buy count1.00
Buy count2.00
Hold count0.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-0.70 Unknown error in universe processing
Last actual EPS-1.29 Unknown error in universe processing
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod financials
no public URL
2026-05-16 21:26 UTC#fb5b3ac7
Source: analysis-pipeline (hybrid)Generated: 2026-05-29 01:37 UTCJob: ec1f7751