OSEBX1,423.56+0.84%
EQNR284.60+4.20%
DNB198.35-1.15%
MOWI172.80+0.45%
Brent$71.24-0.32%
EUR/USD1.0824-0.14%
DXY104.18+0.08%
INDICATIVE · SAMPLE DATA
PRQR$1.5659

ProQR Therapeutics NV

Biotechnology & Medical ResearchVerified

ProQR Therapeutics maintains a market capitalization of $164.3 million and a price-to-book ratio of 3.33, indicating a premium valuation relative to its book value. The company's liquidity position is characterized by a current ratio of 3.09, suggesting it has sufficient short-term assets to cover its liabilities. However, its operating cash flow of -$52.8 million and free cash flow of -$40.5 million highlight significant cash outflows, primarily driven by ongoing R&D and operational costs. The company's profitability metrics are negative, with a return on equity of -85.44% and a return on assets of -37.41%, reflecting substantial losses relative to its equity and asset base. These figures are below the typical performance of the biotechnology industry, where companies often trade at high valuations but may not yet be profitable. ProQR's net loss of $42.2 million and operating loss of $43.4 million further underscore its current unprofitability. Geographically, ProQR's revenue is not disclosed by region, but as a biotechnology firm, it is likely to have a global reach, particularly in North America and Europe, where rare disease therapies are more prevalent and reimbursed. The company's revenue concentration is not explicitly stated, but its focus on a narrow set of rare diseases suggests a high degree of specialization and potential vulnerability to clinical setbacks or regulatory delays. Looking ahead, ProQR is expected to continue incurring losses, with no clear path to profitability in the near term. The company's capital expenditure of -$1.02 million is minimal, but its ongoing R&D efforts are likely to require significant investment. The company's outlook for the current fiscal year is negative, with no significant revenue growth expected. The risk assessment indicates a medium liquidity risk, primarily due to its negative net cash position after accounting for total debt. Recent events, including clinical trial updates and regulatory submissions, are not detailed in the provided data, but the company's ongoing development pipeline and partnerships are likely to be key drivers of its future performance. The risk of dilution is currently low, but the company's need for additional capital could increase this risk in the future.

30-day price · PRQR-0.24 (-13.3%)
Low$1.40High$2.06Close$1.56As of22 May, 00:00 UTC
Profile
CompanyProQR Therapeutics NV
TickerPRQR.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. ProQR Therapeutics NV is a biotechnology company focused on the development of RNA-based therapies for rare diseases, primarily through its proprietary RNA editing platform.

Classification. ProQR Therapeutics is classified under the Biotechnology & Medical Research industry within the Healthcare economic sector, with a classification confidence of 0.92.

ProQR Therapeutics maintains a market capitalization of $164.3 million and a price-to-book ratio of 3.33, indicating a premium valuation relative to its book value. The company's liquidity position is characterized by a current ratio of 3.09, suggesting it has sufficient short-term assets to cover its liabilities. However, its operating cash flow of -$52.8 million and free cash flow of -$40.5 million highlight significant cash outflows, primarily driven by ongoing R&D and operational costs. The company's profitability metrics are negative, with a return on equity of -85.44% and a return on assets of -37.41%, reflecting substantial losses relative to its equity and asset base. These figures are below the typical performance of the biotechnology industry, where companies often trade at high valuations but may not yet be profitable. ProQR's net loss of $42.2 million and operating loss of $43.4 million further underscore its current unprofitability. Geographically, ProQR's revenue is not disclosed by region, but as a biotechnology firm, it is likely to have a global reach, particularly in North America and Europe, where rare disease therapies are more prevalent and reimbursed. The company's revenue concentration is not explicitly stated, but its focus on a narrow set of rare diseases suggests a high degree of specialization and potential vulnerability to clinical setbacks or regulatory delays. Looking ahead, ProQR is expected to continue incurring losses, with no clear path to profitability in the near term. The company's capital expenditure of -$1.02 million is minimal, but its ongoing R&D efforts are likely to require significant investment. The company's outlook for the current fiscal year is negative, with no significant revenue growth expected. The risk assessment indicates a medium liquidity risk, primarily due to its negative net cash position after accounting for total debt. Recent events, including clinical trial updates and regulatory submissions, are not detailed in the provided data, but the company's ongoing development pipeline and partnerships are likely to be key drivers of its future performance. The risk of dilution is currently low, but the company's need for additional capital could increase this risk in the future.
Key takeaways
  • ProQR Therapeutics is a biotechnology company with a focus on RNA-based therapies for rare diseases.
  • The company is currently unprofitable, with significant negative cash flows and a high price-to-book ratio.
  • Its liquidity position is moderate, with a current ratio of 3.09, but it has a negative net cash position after debt.
  • The company's future growth is contingent on successful clinical trials and regulatory approvals, with no clear path to profitability in the near term.
  • --
  • # RATIONALES
  • ```json
  • {
Financial snapshot
PeriodHA-latest
CurrencyUnknown error in universe processing
Revenue$16.3M
Gross profit
Operating income-$43.4M
Net income-$42.2M
R&D
SG&A
D&A
SBC
Operating cash flow-$52.8M
CapEx-$1.0M
Free cash flow-$40.5M
Total assets$112.8M
Total liabilities$63.4M
Total equity$49.4M
Cash & equivalents
Long-term debt$16.0M
Valuation
Market price$1.56
Market cap$164.3M
Enterprise value$180.3M
P/E
Reported non-GAAP P/E
EV/Revenue11.0
EV/Op income
EV/OCF
P/B3.3
P/Tangible book3.3
Tangible book$49.4M
Net cash-$16.0M
Current ratio3.1
Debt/Equity0.3
ROA-37.4%
ROE-85.4%
Cash conversion1.2%
CapEx/Revenue-6.2%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskMedium
  • Net cash is negative after subtracting total debt.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 693 companies
MetricPRQRActivity
Op margin-265.8%2.4% medp25 -91.8% · p75 12.5%bottom quartile
Net margin-258.1%1.2% medp25 -98.4% · p75 10.4%bottom quartile
Gross margin45.6% medp25 29.8% · p75 66.7%
CapEx / revenue-6.2%-5.2% medp25 -15.8% · p75 -1.7%below median
Debt / equity32.0%9.3% medp25 0.1% · p75 43.8%above median
Observations
IR observations
Mean price target9.50 EUR
Median price target9.50 EUR
High price target14.00 EUR
Low price target4.00 EUR
Mean recommendation1.67 (1=strong buy, 5=strong sell)
Strong-buy count3.00
Buy count6.00
Hold count0.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-0.49 EUR
Last actual EPS-0.40 EUR
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod financials
no public URL
2026-05-23 01:40 UTC#7b427789
Source: analysis-pipeline (hybrid)Generated: 2026-05-29 01:53 UTCJob: 40845739