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INDICATIVE · SAMPLE DATA
SLN$7.1359

Silence Therapeutics PLC

Biotechnology & Medical ResearchVerified

Silence Therapeutics maintains a strong liquidity position, with cash and equivalents amounting to $142.71 million, significantly exceeding its total liabilities of $88.96 million, resulting in a current ratio of 12.82. The company's price-to-book ratio of 2.15 suggests that the market values the company at a premium relative to its book value, while the price-to-tangible-book ratio is identical, indicating no intangible assets are being capitalized. The company's profitability metrics are weak, with a net loss of $2.38 million and an operating loss of $5.27 million in the latest period. Return on equity is negative at -1.52%, and return on assets is also negative at -0.97%, both significantly below the industry median for biotechnology firms. These figures suggest the company is not currently generating returns for shareholders or efficiently utilizing its assets. Silence Therapeutics operates in a single business segment focused on RNA-based therapeutics, with no disclosed geographic revenue concentration. The company's operations are primarily centered in the United Kingdom, and it does not report revenue by geographic region, indicating a lack of diversification in its geographic exposure. The company's growth trajectory is uncertain, with no disclosed revenue growth in the latest period. Analysts have provided a wide range of price targets, from $4.00 to $75.00, with a mean of $32.80 and a median of $25.00, reflecting significant uncertainty about the company's future performance. The mean recommendation is 2.00, indicating a "buy" rating, but the absence of "hold" or "sell" ratings suggests a generally optimistic outlook. Risk factors for Silence Therapeutics include its reliance on research and development, which is inherently uncertain and subject to regulatory and clinical delays. The company has no immediate filing-based liquidity or dilution flags, and its debt-to-equity ratio is 0.0, indicating no leverage. However, the company's free cash flow is negative at -$52.24 million, and capital expenditures are also negative, suggesting ongoing investment in R&D and infrastructure. Recent events include the publication of analyst price targets and recommendations, with a strong-buy count of 2 and a buy count of 3. No recent filings or transcripts have been disclosed that would indicate significant changes in the company's strategic direction or financial position.

30-day price · SLN(missing data)
No daily-bar history available from current data sources. Alternate source pending.
Profile
CompanySilence Therapeutics PLC
TickerSLN.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Silence Therapeutics PLC is a biotechnology company focused on the development of RNA-based therapeutics, primarily in the field of healthcare diagnostics and treatment.

Classification. Silence Therapeutics is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

Silence Therapeutics maintains a strong liquidity position, with cash and equivalents amounting to $142.71 million, significantly exceeding its total liabilities of $88.96 million, resulting in a current ratio of 12.82. The company's price-to-book ratio of 2.15 suggests that the market values the company at a premium relative to its book value, while the price-to-tangible-book ratio is identical, indicating no intangible assets are being capitalized. The company's profitability metrics are weak, with a net loss of $2.38 million and an operating loss of $5.27 million in the latest period. Return on equity is negative at -1.52%, and return on assets is also negative at -0.97%, both significantly below the industry median for biotechnology firms. These figures suggest the company is not currently generating returns for shareholders or efficiently utilizing its assets. Silence Therapeutics operates in a single business segment focused on RNA-based therapeutics, with no disclosed geographic revenue concentration. The company's operations are primarily centered in the United Kingdom, and it does not report revenue by geographic region, indicating a lack of diversification in its geographic exposure. The company's growth trajectory is uncertain, with no disclosed revenue growth in the latest period. Analysts have provided a wide range of price targets, from $4.00 to $75.00, with a mean of $32.80 and a median of $25.00, reflecting significant uncertainty about the company's future performance. The mean recommendation is 2.00, indicating a "buy" rating, but the absence of "hold" or "sell" ratings suggests a generally optimistic outlook. Risk factors for Silence Therapeutics include its reliance on research and development, which is inherently uncertain and subject to regulatory and clinical delays. The company has no immediate filing-based liquidity or dilution flags, and its debt-to-equity ratio is 0.0, indicating no leverage. However, the company's free cash flow is negative at -$52.24 million, and capital expenditures are also negative, suggesting ongoing investment in R&D and infrastructure. Recent events include the publication of analyst price targets and recommendations, with a strong-buy count of 2 and a buy count of 3. No recent filings or transcripts have been disclosed that would indicate significant changes in the company's strategic direction or financial position.
Key takeaways
  • Silence Therapeutics has a strong liquidity position with a current ratio of 12.82 and $142.71 million in cash and equivalents.
  • The company is not currently profitable, with a net loss of $2.38 million and a negative return on equity of -1.52%.
  • The company operates in a single segment focused on RNA-based therapeutics, with no geographic revenue diversification.
  • Analysts have provided a wide range of price targets, from $4.00 to $75.00, with a mean of $32.80 and a median of $25.00.
  • The company has no immediate liquidity or dilution risks, but its free cash flow is negative at -$52.24 million.
  • --
  • # RATIONALES
  • ```json
Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$15.7M
Gross profit$12.9M
Operating income-$5.3M
Net income-$2.4M
R&D
SG&A
D&A
SBC
Operating cash flow-$9.5M
CapEx-$50.0M
Free cash flow-$52.2M
Total assets$245.4M
Total liabilities$89.0M
Total equity$156.4M
Cash & equivalents$142.7M
Long-term debt$349.7k
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY-4$17.1M-$63.0M-$54.2M-$55.4M
FY-3$21.7M-$61.0M-$50.3M-$69.7M
FY-2$31.6M-$64.4M-$54.2M-$53.6M
FY-1$43.3M-$63.3M-$45.3M-$44.9M
FY0$559.0k-$91.1M-$88.6M-$88.1M
PeriodGross %Op %Net %FCF %
FY-4
FY-3
FY-2
FY-1
FY0
PeriodAssetsEquityCashDebt
FY-4$130.1M$11.5M
FY-3$130.0M$26.7M
FY-2$119.4M$22.0M
FY-1$202.6M$134.0M
FY0$131.4M$62.3M
PeriodOCFCapExFCFSBC
FY-4$9.4M-$1.8M-$55.4M
FY-3-$57.0M-$545.0k-$69.7M
FY-2-$49.5M-$56.0k-$53.6M
FY-1-$67.6M-$211.0k-$44.9M
FY0-$62.3M-$55.0k-$88.1M
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ-7$15.7M-$5.3M-$2.4M-$52.2M
FQ-6$754.4k-$23.1M-$19.6M-$19.4M
FQ-5$1.5M-$29.3M-$35.1M-$97.6M
FQ-4$124.4M
FQ-3$142.0k-$28.4M-$28.5M-$28.4M
FQ-2$224.0k-$24.0M-$27.4M-$27.3M
FQ-1$159.0k-$26.2M-$21.0M-$20.8M
FQ0$34.0k-$12.5M-$11.8M-$11.7M
PeriodGross %Op %Net %FCF %
FQ-7
FQ-6
FQ-5
FQ-4
FQ-3
FQ-2
FQ-1
FQ0
PeriodAssetsEquityCashDebt
FQ-7$245.4M$156.4M$142.7M
FQ-6$238.5M$142.2M$138.4M
FQ-5$226.5M$126.4M$82.8M
FQ-4$202.6M$134.0M
FQ-3$185.3M$112.7M$64.9M
FQ-2$165.2M$94.2M$41.7M
FQ-1$146.8M$74.1M$82.0M
FQ0$131.4M$62.3M
PeriodOCFCapExFCFSBC
FQ-7-$9.5M-$50.0M-$52.2M
FQ-6-$15.6M-$50.0M-$19.4M
FQ-5-$40.8M-$112.6M-$97.6M
FQ-4-$67.6M-$211.0k$124.4M
FQ-3-$12.3M-$4.0k-$28.4M
FQ-2-$34.1M-$52.0k-$27.3M
FQ-1-$45.0M-$55.0k-$20.8M
FQ0-$62.3M-$55.0k-$11.7M
Valuation
Market price$7.13
Market cap$336.8M
Enterprise value$194.4M
P/E
Reported non-GAAP P/E
EV/Revenue12.4
EV/Op income
EV/OCF
P/B2.1
P/Tangible book2.1
Tangible book$156.4M
Net cash$142.4M
Current ratio12.8
Debt/Equity0.0
ROA-1.0%
ROE-1.5%
Cash conversion4.0%
CapEx/Revenue-3.2%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Healthcare Diagnostics · cohort 170 companies
MetricSLNActivity
Op margin-33.5%-227.5% medp25 -1250.6% · p75 -3.5%above median
Net margin-15.1%-194.5% medp25 -1233.8% · p75 0.8%above median
Gross margin82.2%53.0% medp25 25.9% · p75 75.7%top quartile
CapEx / revenue-317.9%-8.2% medp25 -35.2% · p75 -2.5%bottom quartile
Debt / equity0.0%1.2% medp25 0.0% · p75 17.4%bottom quartile
Observations
IR observations
Mean price target32.80 USD
Median price target25.00 USD
High price target75.00 USD
Low price target4.00 USD
Mean recommendation2.00 (1=strong buy, 5=strong sell)
Strong-buy count2.00
Buy count3.00
Hold count0.00
Sell count1.00
Strong-sell count0.00
Mean EPS estimate-0.56 USD
Last actual EPS-1.89 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-16 23:24 UTC#c414838b
Market quoteclose USD 7.38
no public URL
2026-05-16 23:24 UTC#319963af
Source: analysis-pipeline (hybrid)Generated: 2026-05-29 11:35 UTCJob: 0fe38141