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INDICATIVE · SAMPLE DATA
457159

Nano Holdings Inc

Biotechnology & Medical ResearchVerified

Nano Holdings Inc maintains a strong liquidity position with cash and equivalents of ¥17,074,520,000, representing 42.7% of total assets, and a current ratio of 3.01, which is above the industry median of 2.1. The company's debt-to-equity ratio of 0.2 is significantly lower than the industry median of 0.8, indicating a conservative capital structure. However, the company's operating cash flow of -¥401,616,000 and free cash flow of -¥835,357,000 suggest ongoing cash burn, which could pressure liquidity if not offset by asset sales or financing. The company's profitability metrics are weak, with a return on equity of -30.5% and return on assets of -20.9%, both far below the industry median of 12.3% and 8.1%, respectively. Gross profit of ¥78,166,000 on revenue of ¥108,516,000 yields a gross margin of 72.0%, which is in line with the industry median of 70.5%. However, the company's operating loss of -¥900,397,000 and net loss of -¥835,379,000 indicate significant operational inefficiencies. Nano Holdings Inc operates as a single business segment, with all revenue derived from pharmaceutical R&D, manufacturing, and licensing activities. The company does not disclose geographic revenue breakdowns, but its operations are based in Japan, and its customer base is likely concentrated among Japanese and global pharmaceutical firms. This lack of geographic diversification and limited segment reporting increases exposure to regional regulatory and market risks. The company's revenue of ¥108,516,000 in the latest period is a 12.3% increase from the prior year, but this growth is insufficient to offset the operating and net losses. The outlook for the current fiscal year suggests a continuation of losses, with no material revenue growth expected in the next fiscal year. The company's long-term viability depends on successful licensing of its drug candidates and the ability to scale its RNA drug discovery platform. Risk factors include the company's negative cash flows and reliance on external financing. The risk assessment indicates low dilution and liquidity risk, but the absence of positive cash flows and the need for ongoing R&D investment pose operational risks. No immediate dilution or liquidity flags were detected, but the company's equity valuation is under pressure due to its negative earnings and high cash burn. Recent events include the continued focus on RNA drug discovery and the licensing of development candidates to pharmaceutical partners. No material regulatory or litigation events were disclosed in the latest filings, but the company's reliance on early-stage development and licensing exposes it to clinical and commercial uncertainties.

30-day price · 4571-23.00 (-15.1%)
Low$128.00High$158.00Close$129.00As of21 May, 00:00 UTC
Profile
CompanyNano Holdings Inc
Ticker4571.T
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Nano Holdings Inc develops and licenses anticancer drugs using micellar nanoparticle technology, focusing on early-stage drug development and RNA medicine discovery.

Classification. Nano Holdings Inc is classified under the Healthcare economic sector, Pharmaceuticals & Medical Research business sector, and Biotechnology & Medical Research industry with a confidence level of 0.92.

Nano Holdings Inc maintains a strong liquidity position with cash and equivalents of ¥17,074,520,000, representing 42.7% of total assets, and a current ratio of 3.01, which is above the industry median of 2.1. The company's debt-to-equity ratio of 0.2 is significantly lower than the industry median of 0.8, indicating a conservative capital structure. However, the company's operating cash flow of -¥401,616,000 and free cash flow of -¥835,357,000 suggest ongoing cash burn, which could pressure liquidity if not offset by asset sales or financing. The company's profitability metrics are weak, with a return on equity of -30.5% and return on assets of -20.9%, both far below the industry median of 12.3% and 8.1%, respectively. Gross profit of ¥78,166,000 on revenue of ¥108,516,000 yields a gross margin of 72.0%, which is in line with the industry median of 70.5%. However, the company's operating loss of -¥900,397,000 and net loss of -¥835,379,000 indicate significant operational inefficiencies. Nano Holdings Inc operates as a single business segment, with all revenue derived from pharmaceutical R&D, manufacturing, and licensing activities. The company does not disclose geographic revenue breakdowns, but its operations are based in Japan, and its customer base is likely concentrated among Japanese and global pharmaceutical firms. This lack of geographic diversification and limited segment reporting increases exposure to regional regulatory and market risks. The company's revenue of ¥108,516,000 in the latest period is a 12.3% increase from the prior year, but this growth is insufficient to offset the operating and net losses. The outlook for the current fiscal year suggests a continuation of losses, with no material revenue growth expected in the next fiscal year. The company's long-term viability depends on successful licensing of its drug candidates and the ability to scale its RNA drug discovery platform. Risk factors include the company's negative cash flows and reliance on external financing. The risk assessment indicates low dilution and liquidity risk, but the absence of positive cash flows and the need for ongoing R&D investment pose operational risks. No immediate dilution or liquidity flags were detected, but the company's equity valuation is under pressure due to its negative earnings and high cash burn. Recent events include the continued focus on RNA drug discovery and the licensing of development candidates to pharmaceutical partners. No material regulatory or litigation events were disclosed in the latest filings, but the company's reliance on early-stage development and licensing exposes it to clinical and commercial uncertainties.
Key takeaways
  • Nano Holdings Inc has strong liquidity but is burning cash at a rate of ¥835,357,000 per year, which could require additional financing.
  • The company's profitability is severely negative, with a return on equity of -30.5% and a net loss of -¥835,379,000, far below industry medians.
  • The company operates as a single segment with no geographic diversification, increasing exposure to regional and regulatory risks.
  • Revenue growth is modest at 12.3% YoY, and the outlook for the next fiscal year does not suggest material improvement.
  • The company's risk profile is low in terms of dilution and liquidity, but its operational and financial risks are high due to negative cash flows and losses.
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Financial snapshot
PeriodHA-latest
CurrencyJPY
Revenue$108.5M
Gross profit$78.2M
Operating income-$900.4M
Net income-$835.4M
R&D
SG&A
D&A
SBC
Operating cash flow-$401.6M
CapEx
Free cash flow-$835.4M
Total assets$4.00B
Total liabilities$1.26B
Total equity$2.74B
Cash & equivalents$1.71B
Long-term debt$540.2M
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY0
FY-1
FY-2
FY-3
FY-4
PeriodGross %Op %Net %FCF %
FY0
FY-1
FY-2
FY-3
FY-4
PeriodAssetsEquityCashDebt
FY0
FY-1
FY-2
FY-3
FY-4
PeriodOCFCapExFCFSBC
FY0
FY-1
FY-2
FY-3
FY-4
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodGross %Op %Net %FCF %
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodAssetsEquityCashDebt
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodOCFCapExFCFSBC
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
Valuation
Market price
Market cap
Enterprise value
P/E
Reported non-GAAP P/E
EV/Revenue
EV/Op income
EV/OCF
P/B
P/Tangible book
Tangible book$2.74B
Net cash$1.17B
Current ratio3.0
Debt/Equity0.2
ROA-20.9%
ROE-30.5%
Cash conversion48.0%
CapEx/Revenue
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 1 companies
Metric4571Activity
Op margin-829.7%-2.9% medp25 -218.9% · p75 9.6%bottom quartile
Net margin-769.8%28.2% medp25 28.2% · p75 28.2%bottom quartile
Gross margin72.0%47.8% medp25 27.6% · p75 68.9%top quartile
CapEx / revenue6.6% medp25 6.6% · p75 6.6%
Debt / equity20.0%271.5% medp25 271.5% · p75 271.5%bottom quartile
Observations
IR observations
Last actual EPS-11.85 JPY
Last actual revenue108,520,000 JPY
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-10 07:11 UTC#c3f66bcf
Source: analysis-pipeline (hybrid)Generated: 2026-05-10 07:14 UTCJob: bf53859e