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INDICATIVE · SAMPLE DATA
457259

Carna Biosciences Inc

Biotechnology & Medical ResearchVerified

Carna Biosciences operates with a debt-to-equity ratio of 2.31 and a current ratio of 6.99, indicating a strong liquidity position despite a negative net cash position after subtracting total debt. The company holds 516,789,000 JPY in cash and equivalents, which is partially offset by 714,487,000 JPY in long-term debt. This capital structure suggests a reliance on equity and long-term debt to fund operations, with a high degree of leverage that could amplify losses during periods of declining revenue. The company's profitability metrics are weak, with a return on equity of -7.02% and a return on assets of -1.77%, both significantly below the industry median for biotechnology and medical research firms. These figures reflect a challenging operating environment, with a net loss of 2,171,470,000 JPY and an operating loss of 2,099,730,000 JPY in the latest reporting period. The gross profit margin of 67.0% is relatively strong, but this is insufficient to offset the high operating expenses. Carna Biosciences operates in two segments: Drug Development Support and Drug Development. The Drug Development Support segment generates revenue through the sale of protein kinase, assay development, and profiling and screening services. The Drug Development segment focuses on the research and development of kinase inhibitors and other drugs. However, the company does not disclose revenue by segment, making it difficult to assess the contribution of each business line to overall performance. The company's growth trajectory is uncertain, with no specific revenue growth projections provided in the outlook. The latest financial data shows a revenue of 579,057,000 JPY, but the operating cash flow is negative at -2,159,363,000 JPY, and the free cash flow is also negative at -2,180,750,000 JPY. These figures suggest that the company is not generating sufficient cash from operations to sustain its current level of investment and debt service. The risk assessment for Carna Biosciences indicates a medium liquidity risk and a low dilution risk. The key flag of negative net cash after subtracting total debt highlights the company's reliance on external financing to meet its obligations. The dilution risk is low, as the number of shares outstanding has not changed between basic and diluted shares. However, the company's negative operating and free cash flows could necessitate future equity or debt financing, which may lead to dilution if not managed carefully. Recent events and filings do not provide specific details on new product launches, partnerships, or regulatory approvals. The company's focus on drug development and support services is consistent with its long-term strategy, but the absence of recent positive developments or significant revenue growth suggests that the company is still in a development phase with limited commercial success.

30-day price · 4572+54.00 (+14.0%)
Low$380.00High$492.00Close$439.00As of21 May, 00:00 UTC
Profile
CompanyCarna Biosciences Inc
Ticker4572.T
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Carna Biosciences, Inc. provides drug development support services and engages in the research and development of kinase inhibitors and other drugs.

Classification. Carna Biosciences is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a confidence level of 0.92.

Carna Biosciences operates with a debt-to-equity ratio of 2.31 and a current ratio of 6.99, indicating a strong liquidity position despite a negative net cash position after subtracting total debt. The company holds 516,789,000 JPY in cash and equivalents, which is partially offset by 714,487,000 JPY in long-term debt. This capital structure suggests a reliance on equity and long-term debt to fund operations, with a high degree of leverage that could amplify losses during periods of declining revenue. The company's profitability metrics are weak, with a return on equity of -7.02% and a return on assets of -1.77%, both significantly below the industry median for biotechnology and medical research firms. These figures reflect a challenging operating environment, with a net loss of 2,171,470,000 JPY and an operating loss of 2,099,730,000 JPY in the latest reporting period. The gross profit margin of 67.0% is relatively strong, but this is insufficient to offset the high operating expenses. Carna Biosciences operates in two segments: Drug Development Support and Drug Development. The Drug Development Support segment generates revenue through the sale of protein kinase, assay development, and profiling and screening services. The Drug Development segment focuses on the research and development of kinase inhibitors and other drugs. However, the company does not disclose revenue by segment, making it difficult to assess the contribution of each business line to overall performance. The company's growth trajectory is uncertain, with no specific revenue growth projections provided in the outlook. The latest financial data shows a revenue of 579,057,000 JPY, but the operating cash flow is negative at -2,159,363,000 JPY, and the free cash flow is also negative at -2,180,750,000 JPY. These figures suggest that the company is not generating sufficient cash from operations to sustain its current level of investment and debt service. The risk assessment for Carna Biosciences indicates a medium liquidity risk and a low dilution risk. The key flag of negative net cash after subtracting total debt highlights the company's reliance on external financing to meet its obligations. The dilution risk is low, as the number of shares outstanding has not changed between basic and diluted shares. However, the company's negative operating and free cash flows could necessitate future equity or debt financing, which may lead to dilution if not managed carefully. Recent events and filings do not provide specific details on new product launches, partnerships, or regulatory approvals. The company's focus on drug development and support services is consistent with its long-term strategy, but the absence of recent positive developments or significant revenue growth suggests that the company is still in a development phase with limited commercial success.
Key takeaways
  • Carna Biosciences has a strong liquidity position with a current ratio of 6.99 but faces a negative net cash position after subtracting total debt.
  • The company's profitability is weak, with a return on equity of -7.02% and a return on assets of -1.77%, indicating significant operational challenges.
  • The company operates in two segments, but revenue by segment is not disclosed, limiting visibility into the performance of each business line.
  • The company's growth trajectory is uncertain, with no specific revenue growth projections and negative operating and free cash flows.
  • The risk assessment indicates a medium liquidity risk and a low dilution risk, but the company's reliance on external financing could lead to future dilution if not managed carefully.
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Financial snapshot
PeriodHA-latest
CurrencyJPY
Revenue$579.1M
Gross profit$388.1M
Operating income-$2.10B
Net income-$2.17B
R&D
SG&A
D&A
SBC
Operating cash flow-$2.16B
CapEx-$9.3M
Free cash flow-$2.18B
Total assets$1.23B
Total liabilities$920.4M
Total equity$309.2M
Cash & equivalents$516.8M
Long-term debt$714.5M
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY0$579.1M-$2.10B-$2.17B-$2.18B
FY-1$636.2M-$2.17B-$2.18B-$2.16B
FY-2$1.63B-$1.12B-$1.15B-$1.13B
FY-3$1.39B-$1.31B-$1.35B-$1.44B
FY-4$2.02B-$540.6M-$534.5M-$557.0M
PeriodGross %Op %Net %FCF %
FY0
FY-1
FY-2
FY-3
FY-4
PeriodAssetsEquityCashDebt
FY0$1.23B$309.2M$516.8M
FY-1$2.77B$2.48B$2.11B
FY-2$4.35B$3.88B$2.89B
FY-3$4.27B$3.64B$3.38B
FY-4$5.43B$4.32B$3.82B
PeriodOCFCapExFCFSBC
FY0-$2.16B-$9.3M-$2.18B
FY-1-$1.37B-$13.1M-$2.16B
FY-2-$1.68B-$11.5M-$1.13B
FY-3-$708.4M-$126.0M-$1.44B
FY-4-$1.54B-$41.7M-$557.0M
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ0$183.6M-$539.2M-$571.5M
FQ-1$144.3M-$507.4M-$544.0M
FQ-2$107.8M-$555.7M-$557.0M
FQ-3$143.3M-$497.4M-$499.1M
FQ-4$149.0M-$585.8M-$590.0M
FQ-5$171.6M-$484.3M-$494.5M
FQ-6$134.8M-$680.4M-$695.2M
FQ-7$180.9M-$418.9M-$398.9M
PeriodGross %Op %Net %FCF %
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodAssetsEquityCashDebt
FQ0$1.23B$309.2M$516.8M
FQ-1$1.54B$864.1M$924.8M
FQ-2$1.64B$1.39B$1.06B
FQ-3$2.17B$1.96B$1.53B
FQ-4$2.77B$2.48B$2.11B
FQ-5$2.98B$2.65B$2.28B
FQ-6$3.69B$3.22B$3.03B
FQ-7$3.89B$3.52B$3.16B
PeriodOCFCapExFCFSBC
FQ0-$2.16B-$9.3M
FQ-1
FQ-2-$994.6M-$140.0k
FQ-3
FQ-4-$1.37B-$13.1M
FQ-5
FQ-6-$222.1M-$7.1M
FQ-7
Valuation
Market price
Market cap
Enterprise value
P/E
Reported non-GAAP P/E
EV/Revenue
EV/Op income
EV/OCF
P/B
P/Tangible book
Tangible book$309.2M
Net cash-$197.7M
Current ratio7.0
Debt/Equity2.3
ROA-1.8%
ROE-7.0%
Cash conversion99.0%
CapEx/Revenue-1.6%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskMedium
  • Net cash is negative after subtracting total debt.
Industry benchmarks
Activity: Healthcare Diagnostics · cohort 254 companies
Metric4572Activity
Op margin-362.6%7.0% medp25 3.8% · p75 10.2%bottom quartile
Net margin-375.0%2.4% medp25 -0.6% · p75 5.4%bottom quartile
Gross margin67.0%50.1% medp25 23.6% · p75 72.3%above median
CapEx / revenue-1.6%-6.8% medp25 -27.8% · p75 -1.7%top quartile
Debt / equity231.0%140.5% medp25 104.0% · p75 177.0%top quartile
Observations
IR observations
Last actual EPS-113.62 JPY
Last actual revenue579,060,000 JPY
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-13 00:13 UTC#8b81ab66
Market quoteclose JPY 398.00 · shares 0.02B diluted
no public URL
2026-05-10 02:02 UTC#29ad1b7a
Source: analysis-pipeline (hybrid)Generated: 2026-05-13 00:15 UTCJob: f57a9498