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INDICATIVE · SAMPLE DATA
457659

D.Western Therapeutics Institute Inc

Biotechnology & Medical ResearchVerified

D.Western Therapeutics operates with a strong liquidity position, as evidenced by its cash and equivalents of ¥1.71 billion, which significantly exceeds its total liabilities of ¥734 million, resulting in a current ratio of 9.91. The company's liquidity is further supported by a low debt-to-equity ratio of 0.42, indicating a conservative capital structure with limited leverage. However, the company's operating cash flow is negative at ¥-494 million, and free cash flow is also negative at ¥-587 million, suggesting ongoing operational cash outflows. Profitability metrics are weak, with a return on equity of -44.03% and a return on assets of -29.14%, both significantly below the industry median for biotechnology firms. The company reported a net loss of ¥632 million and an operating loss of ¥619.9 million, reflecting the high costs associated with drug development and limited near-term revenue generation. The company's revenue is concentrated in a single business model—licensing of developed drugs—without disclosed geographic diversification. This lack of segment or geographic diversification increases exposure to market-specific risks, particularly in Japan. No material revenue concentration by region is explicitly reported, but the company's operations are centered in Japan, which may limit its exposure to global markets. Growth trajectory is constrained by the company's current financial position. The company's revenue of ¥387.6 million is modest, and no significant revenue growth is projected in the near term. The outlook for the current fiscal year is flat, with no material changes expected in the next fiscal year. The company's focus on drug development and licensing suggests a long-term growth strategy, but the absence of commercialized products currently limits revenue potential. Risk factors include the high costs and uncertainties of drug development, with no immediate liquidity or dilution flags detected. The company's dilution potential is low, with no recent equity issuance or shelf registration activity reported. However, the company's negative net income and operating cash flow may necessitate future financing, which could lead to dilution. No adjustments to valuation metrics have been applied, indicating that the company's financials are presented without material non-GAAP adjustments. Recent events include the continued development of its drug pipeline, including anti-thrombotic medicine K-134, therapeutic agent K-115 for glaucoma, and anticancer drug HMN-214. The company is also developing new drug candidate compounds focusing on protein kinase inhibitors and ophthalmic surgical adjuvants. No recent filings or transcripts have been disclosed that would indicate material changes in strategy or operations.

30-day price · 4576(missing data)
No daily-bar history available from current data sources. Alternate source pending.
Profile
CompanyD.Western Therapeutics Institute Inc
Ticker4576.T
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. D.Western Therapeutics Institute, Inc. is a Japan-based company engaged in the research and development of new pharmaceuticals, generating revenue primarily from licensing its developed drugs to other companies.

Classification. D.Western Therapeutics is classified under the Healthcare economic sector, specifically in the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

D.Western Therapeutics operates with a strong liquidity position, as evidenced by its cash and equivalents of ¥1.71 billion, which significantly exceeds its total liabilities of ¥734 million, resulting in a current ratio of 9.91. The company's liquidity is further supported by a low debt-to-equity ratio of 0.42, indicating a conservative capital structure with limited leverage. However, the company's operating cash flow is negative at ¥-494 million, and free cash flow is also negative at ¥-587 million, suggesting ongoing operational cash outflows. Profitability metrics are weak, with a return on equity of -44.03% and a return on assets of -29.14%, both significantly below the industry median for biotechnology firms. The company reported a net loss of ¥632 million and an operating loss of ¥619.9 million, reflecting the high costs associated with drug development and limited near-term revenue generation. The company's revenue is concentrated in a single business model—licensing of developed drugs—without disclosed geographic diversification. This lack of segment or geographic diversification increases exposure to market-specific risks, particularly in Japan. No material revenue concentration by region is explicitly reported, but the company's operations are centered in Japan, which may limit its exposure to global markets. Growth trajectory is constrained by the company's current financial position. The company's revenue of ¥387.6 million is modest, and no significant revenue growth is projected in the near term. The outlook for the current fiscal year is flat, with no material changes expected in the next fiscal year. The company's focus on drug development and licensing suggests a long-term growth strategy, but the absence of commercialized products currently limits revenue potential. Risk factors include the high costs and uncertainties of drug development, with no immediate liquidity or dilution flags detected. The company's dilution potential is low, with no recent equity issuance or shelf registration activity reported. However, the company's negative net income and operating cash flow may necessitate future financing, which could lead to dilution. No adjustments to valuation metrics have been applied, indicating that the company's financials are presented without material non-GAAP adjustments. Recent events include the continued development of its drug pipeline, including anti-thrombotic medicine K-134, therapeutic agent K-115 for glaucoma, and anticancer drug HMN-214. The company is also developing new drug candidate compounds focusing on protein kinase inhibitors and ophthalmic surgical adjuvants. No recent filings or transcripts have been disclosed that would indicate material changes in strategy or operations.
Key takeaways
  • D.Western Therapeutics has a strong liquidity position with ¥1.71 billion in cash and equivalents, but negative operating and free cash flows indicate ongoing operational challenges.
  • The company's profitability is weak, with a return on equity of -44.03% and a return on assets of -29.14%, significantly below industry norms.
  • Revenue is concentrated in a single business model—licensing of developed drugs—without geographic diversification, increasing market-specific risk.
  • Growth is constrained by the absence of commercialized products and flat revenue outlook, with no material changes expected in the next fiscal year.
  • The company's risk profile is low in terms of liquidity and dilution, but its reliance on drug development and licensing introduces long-term uncertainty.
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Financial snapshot
PeriodHA-latest
CurrencyJPY
Revenue$387.6M
Gross profit$348.8M
Operating income-$619.9M
Net income-$632.1M
R&D
SG&A
D&A
SBC
Operating cash flow-$493.8M
CapEx-$2.7M
Free cash flow-$587.3M
Total assets$2.17B
Total liabilities$734.0M
Total equity$1.44B
Cash & equivalents$1.71B
Long-term debt$605.2M
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY0
FY-1
FY-2
FY-3
FY-4
PeriodGross %Op %Net %FCF %
FY0
FY-1
FY-2
FY-3
FY-4
PeriodAssetsEquityCashDebt
FY0
FY-1
FY-2
FY-3
FY-4
PeriodOCFCapExFCFSBC
FY0
FY-1
FY-2
FY-3
FY-4
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodGross %Op %Net %FCF %
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodAssetsEquityCashDebt
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodOCFCapExFCFSBC
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
Valuation
Market price
Market cap
Enterprise value
P/E
Reported non-GAAP P/E
EV/Revenue
EV/Op income
EV/OCF
P/B
P/Tangible book
Tangible book$1.44B
Net cash$1.10B
Current ratio9.9
Debt/Equity0.4
ROA-29.1%
ROE-44.0%
Cash conversion78.0%
CapEx/Revenue-0.7%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 1 companies
Metric4576Activity
Op margin-159.9%-2.9% medp25 -218.9% · p75 9.6%below median
Net margin-163.1%28.2% medp25 28.2% · p75 28.2%bottom quartile
Gross margin90.0%47.8% medp25 27.6% · p75 68.9%top quartile
CapEx / revenue-0.7%6.6% medp25 6.6% · p75 6.6%bottom quartile
Debt / equity42.0%271.5% medp25 271.5% · p75 271.5%bottom quartile
Observations
IR observations
Last actual EPS-13.19 JPY
Last actual revenue387,620,000 JPY
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-08 18:13 UTC#bd85db58
Source: analysis-pipeline (hybrid)Generated: 2026-05-03 13:29 UTCJob: c689604c