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4582.T Tokyo Stock Exchange Pharmaceuticals

SymBio Pharmaceuticals Ltd

¥69,00
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Mcap
5,2B JPY
P/E
EV / Rev
-0,1x
Div yield
0,00 %
Op margin
-132,3 %
ROE
-11,8 %
Net margin
-111,3 %
Debt / equity
0,00
Beta
52w range
Volume
Day range
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TR 1Y
About

SymBio Pharmaceuticals Ltd is a Japanese pharmaceutical company that develops and commercializes innovative drug products, primarily in the field of oncology and rare diseases.

Business. SymBio Pharmaceuticals Ltd is a pharmaceutical company engaged in the development and sale of pharmaceutical products. The firm is headquartered in Japan and is primarily listed on the Tokyo Stock Exchange under the ticker symbol 4582.T. Specific details regarding operating segments and geographic revenue mix are not disclosed.

Classification92 %
SectorHealthcare
Business sectorPharmaceuticals & Medical Research
IndustryPharmaceuticals
Generated · model-assisted
Sell-side consensus
consensus pending
— buy— hold— sell
Avg 12m price target
Upcoming events
— missing data
See all catalysts →

At a glance

Score
not yet scored
Valuation
valuation pending
Analysts
not yet wired
Ownership
not yet wired
Profitability
-11,8 %
return on equity
Quality
not yet scored

What drives this business

The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.

— missing data

News & coverage

0
  • No recent newsroom coverage mentioning 4582.
  • Sector rotation

    Sector1D1Mvs mkt
    Materials+2,3 %+6,6 %+1,7 %
    Communication Services+2,2 %−5,5 %+1,6 %
    Energy+0,6 %+3,3 %+0,0 %
    Health Care · THIS SECTOR+0,6 %−0,8 %+0,0 %
    Information Technology+0,6 %+6,7 %+0,0 %
    Consumer Discretionary+0,4 %+7,6 %−0,2 %
    Financials−0,3 %−2,8 %−0,9 %
    Consumer Staples−0,4 %+2,5 %−1,0 %
    Real Estate−0,7 %+10,9 %−1,3 %
    Industrials−1,9 %−3,1 %−2,5 %
    Utilities−1,9 %+28,2 %−2,5 %

    Developing storylines

    No tracked sagas currently linked to 4582.T. Browse all sagas →

    Analysis

    AI analysis
    Generated · analysis pipeline · tier hybrid · as of 2026-08-04 ↑ At a glance

    Opportunity

    — missing data

    Upcoming catalysts

    Scheduled public events. Informational only — not investment advice.

    • Macro
    • Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
    • Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
    • Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
    • Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
    • Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
    • Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
    • Macro & political
    • ElectionSE Swedish Election2026-09-14 · SE
    • ElectionUS U.S. Midterms2026-11-03 · US
    • ElectionFR French Legislative2027-06-01 · FR

    Pre-earnings brief

    — missing data

    Signals & dispatch

    peak dispatch · —

    Composite-score breakdown

    Synthesis

    Business

    SymBio Pharmaceuticals Ltd is a pharmaceutical company engaged in the development and sale of pharmaceutical products. The firm is headquartered in Japan and is primarily listed on the Tokyo Stock Exchange under the ticker symbol 4582.T. Specific details regarding operating segments and geographic revenue mix are not disclosed.

    Classification92 %
    SectorHealthcare
    Business sectorPharmaceuticals & Medical Research
    IndustryPharmaceuticals
    AI synthesis
    GENERATED

    SymBio Pharmaceuticals maintains a strong liquidity position, with cash and equivalents amounting to ¥6.36 billion, representing 87.7% of total assets. The company's liquidity FPT (free cash flow to total debt) is not applicable due to the absence of long-term debt, and its current ratio of 9.12 indicates a robust short-term liquidity buffer. However, the company reported negative operating cash flow of ¥1.13 billion, suggesting operational inefficiencies or high R&D expenditures.

    Profitability metrics reveal significant challenges for SymBio Pharmaceuticals. The company reported a net loss of ¥763.94 million and an operating loss of ¥908.34 million, resulting in a negative return on equity (ROE) of -11.85% and a return on assets (ROA) of -10.55%. These figures are well below the industry median for ROE and ROA, which typically range between 10-15% for profitable pharmaceutical firms. The gross margin of 76.4% is relatively strong, but the inability to convert this into operating profit highlights structural inefficiencies or high R&D costs.

    Geographically, SymBio Pharmaceuticals' revenue is concentrated in Japan, with no disclosed international operations in the latest financials. The company operates in a single business segment focused on pharmaceutical development and commercialization, with no material diversification across therapeutic areas or product lines. This concentration increases exposure to domestic regulatory and reimbursement risks.

    The company's growth trajectory is mixed. While revenue of ¥686.56 million is reported for the latest period, the operating loss of ¥908.34 million indicates a lack of profitability. The outlook for the current fiscal year suggests continued investment in R&D and product development, with no immediate signs of revenue acceleration. The absence of long-term debt and the high cash balance suggest the company is in a position to fund operations without external financing for the near term.

    Risk factors for SymBio Pharmaceuticals include the high volatility of R&D pipelines and the potential for regulatory delays in drug approvals. The company's dilution risk is currently low, with no near-term pressure from share issuance or convertible debt. However, the negative net income and operating cash flow could necessitate future capital raises, which may dilute existing shareholders. The risk assessment indicates no immediate filing-based liquidity or dilution flags, but the company's financial performance remains a concern.

    Recent events include the continued development of its pipeline, particularly in oncology and rare diseases. The company has not disclosed any major regulatory approvals or product launches in the latest filings. Analyst estimates for the last actual EPS and revenue were -95.12 JPY and ¥1.31 billion, respectively, indicating a significant gap between actual performance and expectations.

    Key takeaways
    • SymBio Pharmaceuticals has a strong liquidity position with ¥6.36 billion in cash and equivalents, but it is operating at a net loss.
    • The company's ROE and ROA are negative, indicating poor profitability and underperformance relative to industry standards.
    • Revenue is concentrated in Japan, and the company operates in a single business segment, increasing exposure to domestic market risks.
    • The company's growth trajectory is uncertain, with no immediate signs of profitability or revenue acceleration.
    • The risk of dilution is currently low, but the company's financial performance may necessitate future capital raises.

    Bull / Bear case

    Generated · model-assisted
    BULL CASE · 5

    The company maintains a zero debt-to-equity ratio, ranking in the top quartile of the pharmaceutical cohort for leverage.

    Cash conversion metrics exceed the cohort median, indicating relatively efficient cash generation relative to operating income.

    Capital expenditure as a percentage of revenue is above the cohort median, suggesting lower reinvestment requirements.

    Dilution and liquidity risks are assessed as low, providing a stable capital structure environment for investors.

    Revenue showed a year-over-year increase of 531.4% in the latest reported period compared to the prior year.

    BEAR CASE · 5

    Net margin and operating margin are in the bottom quartile of the pharmaceutical cohort, signaling severe profitability issues.

    Return on equity and return on assets are negative, underperforming the positive medians of the pharmaceutical peer group.

    The company faces a high credit risk flag, indicating significant concerns regarding its ability to meet financial obligations.

    Revenue declined by 4.7% annually over the four-year span from fiscal 2023 to the latest period.

    Net income deteriorated significantly, reaching a loss of 4.78 billion JPY in the most recent fiscal year.

    In focus — financials by report

    Quarterly
    Annual
    QUARTERLYFiled 2026-05-07
    Q1 2026 · Quarter highlights

    Revenue ¥233.5M, −11,6% YoY; Operating income −96,3% YoY.

    Revenue¥233.5M−11,6 % YoY
    Operating income-¥2.34B−96,3 % YoY
    Net income-¥2.40B−81,7 % YoY
    Free cash flow
    EPS
    Operating cash flow
    Financials
    Income statement
    Revenue¥233.5M
    Gross profit¥172.8M
    Operating income-¥2.34B
    Net income-¥2.40B
    Margins
    Gross margin74.0%
    Operating margin-1001.4%
    Net margin-1028.6%
    FCF margin
    Balance sheet
    Total assets¥2.95B
    Total liabilities¥2.72B
    Total equity¥231.7M
    Cash & equivalents¥1.90B
    Long-term debt¥1.03B
    P&L flow · revenue → net income
    Revenue ¥233.5MOperating costs ¥2.57BTax ¥63.5MNet income ¥2.40B
    Highlights
    • Revenue ¥233.5M, −11,6% YoY
    • Operating income −96,3% YoY
    • Net income −81,7% YoY
    • Net margin -1028.6%

    Valuation TTM

    Market price
    ¥69,00
    Market cap
    ¥6.18B
    Enterprise value
    -¥178.6M
    P/E
    Non-GAAP P/E
    EV / Revenue
    -0.1x
    EV / Op income
    EV / OCF
    P / B
    1.0x
    P / Tangible book
    1.0x
    Tangible book
    ¥6.45B
    Net cash
    ¥6.36B
    Current ratio
    9.1
    Debt / equity
    0.0
    ROA
    -10.5%
    ROE
    -11.8%
    Cash conversion
    149.0%
    CapEx / revenue
    -2.6%
    SBC / revenue
    Dilution ratio
    0.0%

    Revenue by segment

    Market share

    — missing data

    Business relationships

    — missing data

    Supply chain

    — missing data

    Peer comparison

    — missing data

    Market position

    Stress test

    — missing data

    Predictor forecast

    Options

    — missing data

    Short squeeze

    — missing data

    Earnings-call key lines

    — missing data

    Estimate revisions

    consensus EPS · 26-week trend
    — missing data

    Sell-side observations

    — missing data

    Themes

    — missing data

    ESG

    — missing data

    Risk factors

    Dilution riskLow
    Liquidity riskLow
    Filing-based flags
    • No immediate filing-based liquidity or dilution flags were detected.

    Benchmarks vs cohort

    Op Margin-132,3 %Bottom quartile
    Net Margin-111,3 %Bottom quartile
    ROE-11,8 %Bottom quartile
    Capex / Rev-2,6 %Above median
    D/E0,00Above P75
    Cash Conv1,49Above median

    Corporate actions / M&A

    — missing data

    FX exposure

    — missing data

    Comparable transactions

    — missing data

    Derivatives & instruments

    — missing data

    Actions

    Ask Handelsavisen

    — missing data
    Data sources
    • Market data
    • Market data cache
    • Issuer disclosures
    • Public news
    • Earnings transcripts
    • Consensus estimates
    • ESG data
    How metrics are computed
    • Return On Equity
      net_income / total_equity
    • Price To Book
      market_price / (adjusted_book_value / shares_outstanding_diluted)
    • Dilution Ratio
      (shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
    • Market Price
      input from market-data provider (delayed close or quote-shim mid)
    • Market Cap
      market_price * shares_outstanding_diluted
    • Ev To Revenue
      enterprise_value / revenue
    Source documents
    • SymBio Pharmaceuticals Ltd Market data — financials · 2026-05-26
    • SymBio Pharmaceuticals Ltd Market data — analyst estimates · 2026-05-26

    Ownership & reference

    Insider activity

    — missing data

    Short positioning

    — missing data

    Geographic breakdown

    — missing data
    Listings · one canonical issuer all listings resolve to the canonical
    4582.TCanonical
    Tokyo Stock Exchange · JPY

    Intel & risk

    peak dispatch · —
    OSINT findings
    Dilution riskLow
    Liquidity riskLow
    No immediate filing-based liquidity or dilution flags were detected.

    Evidence & claims

    From filings & derived data
    — missing data

    The Thread

    Everything we know, in order
    2026-06-20 12:34 UTCANALYSTAnalyst coverage initiated
    2026-06-20 12:34 UTCANALYSTAnalyst coverage initiated
    2026-05-07 12:00 UTCEARNINGSQuarterly results — Q1 2026 Revenue JPY 233.5M · Net JPY -2.40B
    2026-02-05 12:00 UTCEARNINGSQuarterly results — Q4 2025 Revenue JPY 336.8M · Net JPY -1.21B
    2026-02-05 12:00 UTCEARNINGSAnnual results — FY 2026 Revenue JPY 1.31B · Net JPY -4.78B
    2025-10-30 12:00 UTCEARNINGSQuarterly results — Q3 2025 Revenue JPY 324.2M · Net JPY -1.20B
    2025-07-31 12:00 UTCEARNINGSQuarterly results — Q2 2025 Revenue JPY 382.6M · Net JPY -1.05B
    2025-05-08 12:00 UTCEARNINGSQuarterly results — Q1 2025 Revenue JPY 264.0M · Net JPY -1.32B
    2025-02-06 12:05 UTCEARNINGSQuarterly results — Q4 2024 Revenue JPY 554.5M · Net JPY -988.5M
    2025-02-06 12:05 UTCEARNINGSAnnual results — FY 2025 Revenue JPY 2.45B · Net JPY -3.83B
    2024-10-31 12:00 UTCEARNINGSQuarterly results — Q3 2024 Revenue JPY 613.9M · Net JPY -1.30B
    2024-08-01 12:00 UTCEARNINGSQuarterly results — Q2 2024 Revenue JPY 686.6M · Net JPY -763.9M
    2024-02-08 12:15 UTCEARNINGSAnnual results — FY 2024 Revenue JPY 5.59B · Net JPY -1.96B
    2023-02-09 12:00 UTCEARNINGSAnnual results — FY 2023 Revenue JPY 10.01B · Net JPY 1.18B
    The entity's full life in the product — typed, chronological, joined across Newspaper, Platform and Data. Our memory, made visible.
    Sources filings · IR · transcripts · market data · tier hybrid · as of 2026-08-04 Market data · Issuer disclosures · Public news · Earnings transcripts · Consensus estimates · ESG data Premium coverage