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INDICATIVE · SAMPLE DATA
4582$92.0058

SymBio Pharmaceuticals Ltd

PharmaceuticalsVerified

SymBio Pharmaceuticals operates with a market price of 92.0 JPY per share, translating to a market capitalization of 6,837,232,172 JPY. The company's price-to-book ratio is 5.38, and its enterprise value to revenue is 4.54, indicating a premium valuation relative to its tangible assets and revenue base. The company's liquidity position is characterized by a current ratio of 2.96, suggesting a strong ability to meet short-term obligations, supported by 2,883,503,000 JPY in cash and equivalents. Profitability metrics reveal a challenging financial landscape for SymBio. The company reported a net loss of 4,776,193,000 JPY and an operating loss of 4,541,424,000 JPY, resulting in a negative return on equity of -3.75% and a return on assets of -1.24%. These figures are significantly below the industry median for profitability, indicating a need for strategic improvements in cost management and revenue generation. SymBio's revenue is concentrated in three therapeutic areas: cancer, blood diseases, and autoimmune diseases. The company's pipeline includes anticancer drugs such as SyB L-0501, SyB L-1101, and SyB C-1101, which are in various stages of development. The geographic exposure is primarily domestic, with limited international sales, which may limit growth potential in the face of domestic market saturation. The company's growth trajectory is currently negative, with a net loss and declining operating income. The outlook for the current fiscal year is not promising, with no significant revenue growth expected. The company's capital expenditure of -82,472,000 JPY indicates a focus on cost control rather than expansion. The risk assessment indicates low liquidity and dilution risks, with no immediate filing-based flags detected. Recent events include the disclosure of a significant net loss and a negative return on equity, which may impact investor sentiment. The company's financial snapshot shows a high debt-to-equity ratio of 1.56, indicating a leveraged capital structure that could pose risks in a rising interest rate environment. The company's liquidity position is supported by a strong cash balance, but the negative operating cash flow of -4,575,568,000 JPY suggests ongoing operational challenges.

30-day price · 4582-26.00 (-24.1%)
Low$79.00High$112.00Close$82.00As of21 May, 00:00 UTC
Profile
CompanySymBio Pharmaceuticals Ltd
Ticker4582.T
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryPharmaceuticals
AI analysis

Business. SymBio Pharmaceuticals Limited is a Japan-based pharmaceutical company engaged in the design and operation of clinical tests, the manufacture and sale of new drugs specializing in cancer, blood diseases, and autoimmune diseases.

Classification. SymBio is classified under the Healthcare economic sector, Pharmaceuticals & Medical Research business sector, and Pharmaceuticals industry with a confidence level of 0.92.

SymBio Pharmaceuticals operates with a market price of 92.0 JPY per share, translating to a market capitalization of 6,837,232,172 JPY. The company's price-to-book ratio is 5.38, and its enterprise value to revenue is 4.54, indicating a premium valuation relative to its tangible assets and revenue base. The company's liquidity position is characterized by a current ratio of 2.96, suggesting a strong ability to meet short-term obligations, supported by 2,883,503,000 JPY in cash and equivalents. Profitability metrics reveal a challenging financial landscape for SymBio. The company reported a net loss of 4,776,193,000 JPY and an operating loss of 4,541,424,000 JPY, resulting in a negative return on equity of -3.75% and a return on assets of -1.24%. These figures are significantly below the industry median for profitability, indicating a need for strategic improvements in cost management and revenue generation. SymBio's revenue is concentrated in three therapeutic areas: cancer, blood diseases, and autoimmune diseases. The company's pipeline includes anticancer drugs such as SyB L-0501, SyB L-1101, and SyB C-1101, which are in various stages of development. The geographic exposure is primarily domestic, with limited international sales, which may limit growth potential in the face of domestic market saturation. The company's growth trajectory is currently negative, with a net loss and declining operating income. The outlook for the current fiscal year is not promising, with no significant revenue growth expected. The company's capital expenditure of -82,472,000 JPY indicates a focus on cost control rather than expansion. The risk assessment indicates low liquidity and dilution risks, with no immediate filing-based flags detected. Recent events include the disclosure of a significant net loss and a negative return on equity, which may impact investor sentiment. The company's financial snapshot shows a high debt-to-equity ratio of 1.56, indicating a leveraged capital structure that could pose risks in a rising interest rate environment. The company's liquidity position is supported by a strong cash balance, but the negative operating cash flow of -4,575,568,000 JPY suggests ongoing operational challenges.
Key takeaways
  • SymBio Pharmaceuticals is currently unprofitable, with a net loss of 4,776,193,000 JPY and a negative return on equity of -3.75%.
  • The company's liquidity position is strong, with a current ratio of 2.96 and 2,883,503,000 JPY in cash and equivalents.
  • SymBio's revenue is concentrated in three therapeutic areas, with limited international sales, which may limit growth potential.
  • The company's capital structure is highly leveraged, with a debt-to-equity ratio of 1.56.
  • The company's growth trajectory is negative, with no significant revenue growth expected in the near term.
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Financial snapshot
PeriodHA-latest
CurrencyJPY
Revenue$1.31B
Gross profit$947.3M
Operating income-$4.54B
Net income-$4.78B
R&D
SG&A
D&A
SBC
Operating cash flow-$4.58B
CapEx-$82.5M
Free cash flow
Total assets$3.87B
Total liabilities$2.60B
Total equity$1.27B
Cash & equivalents$2.88B
Long-term debt$1.98B
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY0$1.31B-$4.54B-$4.78B
FY-1$2.45B-$3.99B-$3.83B
FY-2$5.59B-$1.30B-$1.96B-$2.10B
FY-3$10.01B$2.07B$1.18B$1.23B
FY-4$8.26B$1.02B$2.03B$2.06B
PeriodGross %Op %Net %FCF %
FY0
FY-1
FY-2
FY-3
FY-4
PeriodAssetsEquityCashDebt
FY0$3.87B$1.27B$2.88B
FY-1$4.97B$4.20B$3.96B
FY-2$8.17B$7.21B$6.52B
FY-3$10.43B$8.51B$6.28B
FY-4$8.45B$6.75B$3.86B
PeriodOCFCapExFCFSBC
FY0-$4.58B-$82.5M
FY-1-$3.42B-$46.9M
FY-2-$194.7M-$232.8M-$2.10B
FY-3$1.63B-$47.6M$1.23B
FY-4$140.0M-$63.8M$2.06B
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ0$233.5M-$2.34B-$2.40B
FQ-1$336.8M-$1.18B-$1.21B
FQ-2$324.2M-$1.19B-$1.20B
FQ-3$382.6M-$979.8M-$1.05B
FQ-4$264.0M-$1.19B-$1.32B
FQ-5$554.5M-$1.14B-$988.5M
FQ-6$613.9M-$1.09B-$1.30B
FQ-7$686.6M-$908.3M-$763.9M
PeriodGross %Op %Net %FCF %
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodAssetsEquityCashDebt
FQ0$2.95B$231.7M$1.90B
FQ-1$3.87B$1.27B$2.88B
FQ-2$4.58B$1.65B$3.46B
FQ-3$4.14B$2.36B$3.05B
FQ-4$4.67B$3.40B$3.61B
FQ-5$4.97B$4.20B$3.96B
FQ-6$6.07B$5.16B$5.13B
FQ-7$7.24B$6.45B$6.36B
PeriodOCFCapExFCFSBC
FQ0
FQ-1-$4.58B-$82.5M
FQ-2
FQ-3-$2.51B
FQ-4
FQ-5-$3.42B-$46.9M
FQ-6
FQ-7-$1.13B-$18.1M
Valuation
Market price$92.00
Market cap$6.84B
Enterprise value$5.94B
P/E
Reported non-GAAP P/E
EV/Revenue4.5
EV/Op income
EV/OCF
P/B5.4
P/Tangible book5.4
Tangible book$1.27B
Net cash$901.0M
Current ratio3.0
Debt/Equity1.6
ROA-1.2%
ROE-3.8%
Cash conversion96.0%
CapEx/Revenue-6.3%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Pharmaceuticals · cohort 25 companies
Metric4582Activity
Op margin-347.3%18.2% medp25 18.2% · p75 24.6%bottom quartile
Net margin-365.3%14.7% medp25 11.7% · p75 28.1%bottom quartile
Gross margin72.4%19.7% medp25 19.7% · p75 39.8%top quartile
R&D / revenue24.3% medp25 6.6% · p75 24.3%
CapEx / revenue-6.3%4.9% medp25 4.2% · p75 6.3%bottom quartile
Debt / equity156.0%71.3% medp25 19.0% · p75 91.7%top quartile
Observations
IR observations
Last actual EPS-95.12 JPY
Last actual revenue1,307,650,000 JPY
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-12 00:27 UTC#e55b1a97
Market quoteclose JPY 92.00 · shares 0.07B diluted
no public URL
2026-05-12 00:27 UTC#527a9f8f
Source: analysis-pipeline (hybrid)Generated: 2026-05-12 00:31 UTCJob: e3f61e54