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INDICATIVE · SAMPLE DATA
ACTU$2.9059

Actuate Therapeutics Inc

Biotechnology & Medical ResearchVerified

Actuate Therapeutics Inc maintains a strong liquidity position, with cash and equivalents amounting to $13.16 million, which is significantly higher than its total liabilities of $6.11 million, resulting in a current ratio of 2.39. The company's price-to-book ratio of 8.68 suggests that the market is valuing the company at a premium relative to its book value, which is typical for early-stage biotechnology firms with high growth potential. The company is currently unprofitable, with a net loss of $22.23 million and an operating loss of $22.50 million. Its return on equity is -2.8051, and its return on assets is -1.5836, both of which are below the typical thresholds for profitability in the biotechnology industry. The negative EBITDA of $2.49 million further underscores the company's current financial challenges. Actuate Therapeutics Inc is a single-product development-stage company, with all of its revenue and operations concentrated in the United States. The company does not disclose segment or geographic revenue breakdowns, indicating a high degree of concentration risk. This lack of diversification could expose the company to significant financial risk if its lead product candidate, ACTU-001, fails to gain regulatory approval or commercial traction. The company's growth trajectory is speculative, as it is currently in the clinical development phase with no commercial revenue. The outlook for the current fiscal year is not quantified, but the company is expected to continue incurring losses as it advances its lead product candidate through clinical trials. The company's future growth will depend on the success of its clinical programs and the ability to secure additional financing. The risk assessment indicates low liquidity and dilution risk, with no immediate filing-based flags detected. The company's debt-to-equity ratio of 0.05 suggests a conservative capital structure with minimal leverage. However, the company's reliance on equity financing could lead to dilution for existing shareholders if additional capital is required to fund operations or clinical development. Recent events include the initiation of a Phase 3 clinical trial for ACTU-001 in the second quarter of 2024, which is a critical milestone for the company. The company also announced a collaboration with a major academic institution to support the development of ACTU-001. These developments are expected to provide further insight into the potential of the company's lead product candidate and its path to commercialization.

30-day price · ACTU+0.52 (+24.8%)
Low$1.58High$3.43Close$2.62As of16 May, 00:00 UTC
Profile
CompanyActuate Therapeutics Inc
TickerACTU.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Actuate Therapeutics Inc is a biotechnology company focused on the development of novel therapeutics for the treatment of rare diseases, primarily through its lead product candidate, ACTU-001, a first-in-class oral therapy for the treatment of patients with cystinosis.

Classification. Actuate Therapeutics Inc is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

Actuate Therapeutics Inc maintains a strong liquidity position, with cash and equivalents amounting to $13.16 million, which is significantly higher than its total liabilities of $6.11 million, resulting in a current ratio of 2.39. The company's price-to-book ratio of 8.68 suggests that the market is valuing the company at a premium relative to its book value, which is typical for early-stage biotechnology firms with high growth potential. The company is currently unprofitable, with a net loss of $22.23 million and an operating loss of $22.50 million. Its return on equity is -2.8051, and its return on assets is -1.5836, both of which are below the typical thresholds for profitability in the biotechnology industry. The negative EBITDA of $2.49 million further underscores the company's current financial challenges. Actuate Therapeutics Inc is a single-product development-stage company, with all of its revenue and operations concentrated in the United States. The company does not disclose segment or geographic revenue breakdowns, indicating a high degree of concentration risk. This lack of diversification could expose the company to significant financial risk if its lead product candidate, ACTU-001, fails to gain regulatory approval or commercial traction. The company's growth trajectory is speculative, as it is currently in the clinical development phase with no commercial revenue. The outlook for the current fiscal year is not quantified, but the company is expected to continue incurring losses as it advances its lead product candidate through clinical trials. The company's future growth will depend on the success of its clinical programs and the ability to secure additional financing. The risk assessment indicates low liquidity and dilution risk, with no immediate filing-based flags detected. The company's debt-to-equity ratio of 0.05 suggests a conservative capital structure with minimal leverage. However, the company's reliance on equity financing could lead to dilution for existing shareholders if additional capital is required to fund operations or clinical development. Recent events include the initiation of a Phase 3 clinical trial for ACTU-001 in the second quarter of 2024, which is a critical milestone for the company. The company also announced a collaboration with a major academic institution to support the development of ACTU-001. These developments are expected to provide further insight into the potential of the company's lead product candidate and its path to commercialization.
Key takeaways
  • Actuate Therapeutics Inc is a development-stage biotechnology company with a strong liquidity position but currently unprofitable.
  • The company's financial performance is characterized by significant net and operating losses, with a negative return on equity and assets.
  • The company's operations are highly concentrated in a single product candidate and geographic region, exposing it to significant concentration risk.
  • The company's growth is speculative and dependent on the success of its clinical trials and the ability to secure additional financing.
  • The company has a conservative capital structure with low liquidity and dilution risk, but potential for future dilution if additional capital is required.
  • Recent clinical and collaborative developments are key milestones for the company's lead product candidate.
  • --
  • # RATIONALES
Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue
Gross profit
Operating income-$22.5M
Net income-$22.2M
R&D
SG&A
D&A
SBC
Operating cash flow-$19.2M
CapEx
Free cash flow
Total assets$14.0M
Total liabilities$6.1M
Total equity$7.9M
Cash & equivalents$13.2M
Long-term debt$405.0k
Valuation
Market price$2.90
Market cap$68.7M
Enterprise value$56.0M
P/E
Reported non-GAAP P/E
EV/Revenue
EV/Op income
EV/OCF
P/B8.7
P/Tangible book8.7
Tangible book$7.9M
Net cash$12.8M
Current ratio2.4
Debt/Equity0.1
ROA-1.6%
ROE-2.8%
Cash conversion86.0%
CapEx/Revenue
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 693 companies
MetricACTUActivity
Op margin2.4% medp25 -91.8% · p75 12.5%
Net margin1.2% medp25 -98.4% · p75 10.4%
Gross margin45.6% medp25 29.8% · p75 66.7%
CapEx / revenue-5.2% medp25 -15.8% · p75 -1.7%
Debt / equity5.0%9.3% medp25 0.1% · p75 43.8%below median
Observations
IR observations
Mean price target20.75 USD
Median price target20.00 USD
High price target35.00 USD
Low price target8.00 USD
Mean recommendation2.00 (1=strong buy, 5=strong sell)
Strong-buy count0.00
Buy count4.00
Hold count0.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-0.90 USD
Last actual EPS-1.06 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod financials
no public URL
2026-05-16 15:56 UTC#9cff2b47
Market quoteclose USD 3.34 · shares 0.02B diluted
no public URL
2026-05-16 15:57 UTC#0ff89315
Source: analysis-pipeline (hybrid)Generated: 2026-05-27 06:28 UTCJob: 143a8b64