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INDICATIVE · SAMPLE DATA
ALVIO$0.1758

Valerio Therapeutics SA

PharmaceuticalsVerified

Valerio Therapeutics operates with a negative equity position of EUR -8.93 million and a current ratio of 0.25, indicating significant liquidity constraints. The company's market capitalization is EUR 26.24 million, with a negative EV/EBITDA of -1.39 and an EV/Revenue of 18.45, both of which are unfavorable compared to industry norms. The company's cash and equivalents amount to EUR 1.18 million, while its long-term debt stands at EUR 8.03 million. The company's profitability is challenged, with a net loss of EUR 23.92 million and an operating loss of EUR 23.73 million. Its return on equity is 2.68%, which is positive but modest, while its return on assets is -1.33%, indicating poor asset utilization. The debt-to-equity ratio is -0.9, suggesting a high reliance on debt financing in a negative equity context. Valerio Therapeutics' revenue is concentrated in a few products, with Beleodaq, Loramyc, and Sitavig being the primary contributors. The company's geographic exposure is primarily in the United States and Europe, with no significant diversification into other regions. The company's revenue of EUR 1.79 million is modest, and its growth trajectory is uncertain given the current financial position. The company's outlook for the current fiscal year is negative, with a net loss expected to continue. The next fiscal year is projected to show a similar trend, with no significant improvement in revenue or profitability. The company's capital expenditures are minimal, with a negative value of EUR -0.32 million, indicating a lack of investment in growth. The company's risk assessment indicates a medium liquidity risk and a low dilution risk. The key financial flag is the negative net cash position after subtracting total debt, which suggests a high risk of insolvency. The company's dilution potential is low, but the negative equity position could lead to further dilution if the company requires additional financing. Recent events include the continued development of Livatag and Validive, with no significant new product launches or regulatory approvals reported. The company's recent financial filings indicate ongoing losses and a lack of positive momentum in its financial performance.

30-day price · ALVIO+0.07 (+65.1%)
Low$0.10High$0.27Close$0.19As of19 May, 00:00 UTC
Profile
CompanyValerio Therapeutics SA
TickerALVIO.PA
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryPharmaceuticals
AI analysis

Business. Valerio Therapeutics SA is a clinical-stage biotechnology company focused on developing therapies targeting tumor DNA functions through unique mechanisms of action in the DNA damage response (DDR) field, with a portfolio including Livatag, Validive, and Beleodaq.

Classification. Valerio Therapeutics is classified under the Healthcare sector, specifically in the Pharmaceuticals & Medical Research business sector, with a high confidence level of 0.92.

Valerio Therapeutics operates with a negative equity position of EUR -8.93 million and a current ratio of 0.25, indicating significant liquidity constraints. The company's market capitalization is EUR 26.24 million, with a negative EV/EBITDA of -1.39 and an EV/Revenue of 18.45, both of which are unfavorable compared to industry norms. The company's cash and equivalents amount to EUR 1.18 million, while its long-term debt stands at EUR 8.03 million. The company's profitability is challenged, with a net loss of EUR 23.92 million and an operating loss of EUR 23.73 million. Its return on equity is 2.68%, which is positive but modest, while its return on assets is -1.33%, indicating poor asset utilization. The debt-to-equity ratio is -0.9, suggesting a high reliance on debt financing in a negative equity context. Valerio Therapeutics' revenue is concentrated in a few products, with Beleodaq, Loramyc, and Sitavig being the primary contributors. The company's geographic exposure is primarily in the United States and Europe, with no significant diversification into other regions. The company's revenue of EUR 1.79 million is modest, and its growth trajectory is uncertain given the current financial position. The company's outlook for the current fiscal year is negative, with a net loss expected to continue. The next fiscal year is projected to show a similar trend, with no significant improvement in revenue or profitability. The company's capital expenditures are minimal, with a negative value of EUR -0.32 million, indicating a lack of investment in growth. The company's risk assessment indicates a medium liquidity risk and a low dilution risk. The key financial flag is the negative net cash position after subtracting total debt, which suggests a high risk of insolvency. The company's dilution potential is low, but the negative equity position could lead to further dilution if the company requires additional financing. Recent events include the continued development of Livatag and Validive, with no significant new product launches or regulatory approvals reported. The company's recent financial filings indicate ongoing losses and a lack of positive momentum in its financial performance.
Key takeaways
  • Valerio Therapeutics is a clinical-stage biotechnology company with a focus on DNA damage response therapies.
  • The company is operating with a negative equity position and significant liquidity constraints.
  • The company's profitability is challenged, with a net loss and a negative return on assets.
  • The company's revenue is modest and concentrated in a few products, with no significant geographic diversification.
  • The company's outlook for the current and next fiscal years is negative, with no significant improvement in revenue or profitability expected.
  • --
  • ## RATIONALES
  • ```json
Financial snapshot
PeriodHA-latest
CurrencyEUR
Revenue$1.8M
Gross profit$1.3M
Operating income-$23.7M
Net income-$23.9M
R&D
SG&A
D&A
SBC
Operating cash flow-$8.4M
CapEx-$319.0k
Free cash flow-$23.6M
Total assets$17.9M
Total liabilities$26.9M
Total equity-$8.9M
Cash & equivalents$1.2M
Long-term debt$8.0M
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY0
FY-1
FY-2
FY-3
FY-4
PeriodGross %Op %Net %FCF %
FY0
FY-1
FY-2
FY-3
FY-4
PeriodAssetsEquityCashDebt
FY0
FY-1
FY-2
FY-3
FY-4
PeriodOCFCapExFCFSBC
FY0
FY-1
FY-2
FY-3
FY-4
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodGross %Op %Net %FCF %
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodAssetsEquityCashDebt
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodOCFCapExFCFSBC
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
Valuation
Market price$0.17
Market cap$26.2M
Enterprise value$33.1M
P/E
Reported non-GAAP P/E
EV/Revenue18.4
EV/Op income
EV/OCF
P/B
P/Tangible book
Tangible book-$8.9M
Net cash-$6.8M
Current ratio0.2
Debt/Equity-0.9
ROA-1.3%
ROE2.7%
Cash conversion35.0%
CapEx/Revenue-17.8%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskMedium
  • Net cash is negative after subtracting total debt.
Industry benchmarks
Activity: Pharmaceuticals · cohort 25 companies
MetricALVIOActivity
Op margin-1323.2%18.2% medp25 18.2% · p75 24.6%bottom quartile
Net margin-1334.0%14.7% medp25 11.7% · p75 28.1%bottom quartile
Gross margin71.4%19.7% medp25 19.7% · p75 39.8%top quartile
R&D / revenue24.3% medp25 6.6% · p75 24.3%
CapEx / revenue-17.8%4.9% medp25 4.2% · p75 6.3%bottom quartile
Debt / equity-90.0%71.3% medp25 19.0% · p75 91.7%bottom quartile
Observations
IR observations
Last actual EPS-0.15 EUR
Last actual revenue1,800,000 EUR
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-10 07:38 UTC#2c409787
Market quoteclose EUR 0.17 · shares 0.15B diluted
no public URL
2026-05-10 07:38 UTC#e52cc480
Source: analysis-pipeline (hybrid)Generated: 2026-05-10 07:40 UTCJob: e836e817