Handelsavisen
prelaunch
Companies Healthcare ANVS.K
AN
ANVS.K NYSE Biotechnology & Medical Research

Annovis Bio Inc

$2,06
Open in Charts → Attach watcher ⌖
USD
Set alert
Last 30 days
1D5D1M3M6MYTD1Y5YMax
Live price chart loads from the market-data widget.
Mcap
71,4M USD
P/E
EV / Rev
Div yield
Op margin
ROE
-171,2 %
Net margin
Debt / equity
0,00
Beta
52w range
Volume
Day range
Prev close
Open
Next earnings
2026-10-28
Ex-dividend
TR 1Y
About

Annovis Bio Inc is a clinical-stage biopharmaceutical company focused on the development of therapies for neurodegenerative diseases, including Alzheimer's and Parkinson's.

Business. Annovis Bio Inc (ANVS.K) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the New York Stock Exchange. Specific details regarding operating segments and geographic revenue mix are not available.

Classification92 %
SectorHealthcare
Business sectorPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
ActivityPharmaceuticals & Medical Research
Generated · model-assisted
Sell-side consensus
BUY4 analysts
4 buy0 hold0 sell
Avg 12m price target15,67

Analyst recommendations

4 analysts · consensus Buy
Buy4
Hold0
Sell0
12-month price target
15,67
Consensus of sell-side coverage.
Upcoming events
  • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
See all catalysts →

At a glance

Score
not yet scored
Valuation
valuation pending
Analysts
Buy
4 analysts · indicative
Ownership
Vanguard Capital Management, LLC
largest disclosed fund holder
Profitability
-171,2 %
return on equity
Quality
not yet scored

What drives this business

The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.

— missing data

News & coverage

0
  • No recent newsroom coverage mentioning ANVS.
  • Sector rotation

    Sector1D1Mvs mkt
    Materials+2,3 %+6,6 %+1,7 %
    Communication Services+2,2 %−5,5 %+1,6 %
    Energy+0,6 %+3,3 %+0,0 %
    Health Care · THIS SECTOR+0,6 %−0,8 %+0,0 %
    Information Technology+0,6 %+6,7 %+0,0 %
    Consumer Discretionary+0,4 %+7,6 %−0,2 %
    Financials−0,3 %−2,8 %−0,9 %
    Consumer Staples−0,4 %+2,5 %−1,0 %
    Real Estate−0,7 %+10,9 %−1,3 %
    Industrials−1,9 %−3,1 %−2,5 %
    Utilities−1,9 %+28,2 %−2,5 %

    Developing storylines

    No tracked sagas currently linked to ANVS.K. Browse all sagas →

    Analysis

    AI analysis
    Generated · analysis pipeline · tier hybrid · as of 2026-08-04 ↑ At a glance

    Opportunity

    — missing data

    Upcoming catalysts

    Scheduled public events. Informational only — not investment advice.

    • Company
    • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
    • Macro
    • Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
    • Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
    • Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
    • Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
    • Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
    • Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
    • Macro & political
    • ElectionSE Swedish Election2026-09-14 · SE
    • ElectionUS U.S. Midterms2026-11-03 · US
    • ElectionFR French Legislative2027-06-01 · FR

    Pre-earnings brief

    — missing data

    Signals & dispatch

    peak dispatch · —

    Composite-score breakdown

    Synthesis

    Business

    Annovis Bio Inc (ANVS.K) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the New York Stock Exchange. Specific details regarding operating segments and geographic revenue mix are not available.

    Classification92 %
    SectorHealthcare
    Business sectorPharmaceuticals & Medical Research
    IndustryBiotechnology & Medical Research
    ActivityPharmaceuticals & Medical Research
    AI synthesis
    GENERATED

    Annovis Bio Inc has a market capitalization of $73.8 million and a price-to-book ratio of 4.38, indicating a premium valuation relative to its book value. The company holds $19.5 million in cash and equivalents, with no long-term debt, and a current ratio of 5.8, suggesting strong short-term liquidity. However, the company reported a net loss of $28.9 million and an operating loss of $29.7 million, with negative returns on equity (-17.1%) and assets (-13.7%).

    The company's financial performance is below the typical metrics for the biotechnology industry, which often includes high R&D expenses and long development cycles. The negative EBITDA of -$1.8 million and the absence of revenue from operations highlight the early-stage nature of its business model. The company's capital structure is entirely equity-based, with no debt, and a debt-to-equity ratio of 0.0.

    Annovis Bio Inc operates in a single business segment focused on neurodegenerative disease therapies. The company's geographic exposure is not disclosed in the available data, but as a clinical-stage biopharmaceutical firm, it likely targets global markets for its drug candidates. The company's revenue concentration is not disclosed, but as a pre-revenue entity, it is not yet generating product-based income.

    The company is in a high-growth phase, with no revenue to date and a focus on clinical development. Analysts have assigned a mean price target of $15.67 and a median of $17.00, with four "buy" ratings and no "strong buy" or "hold" ratings. The company's outlook for the current fiscal year is not disclosed, but the absence of revenue and ongoing losses suggest a continuation of investment in R&D and clinical trials.

    The company's risk profile is characterized by low liquidity and dilution risk, with no immediate filing-based flags detected. The company has a low dilution risk, with no near-term pressure for additional equity issuance. The absence of long-term debt and the presence of $19.5 million in cash and equivalents provide a buffer against short-term liquidity challenges. However, the company's reliance on equity financing and the absence of revenue expose it to dilution risk in the long term.

    Recent events include the publication of analyst price targets and the absence of any significant regulatory or operational filings. The company's focus on clinical development and the absence of revenue suggest that its near-term financial performance will be driven by the progress of its drug candidates through clinical trials.

    Key takeaways
    • Annovis Bio Inc is a clinical-stage biopharmaceutical company with no revenue and ongoing losses.
    • The company has strong liquidity with $19.5 million in cash and no debt, but is not yet generating revenue.
    • Analysts have assigned a mean price target of $15.67, with four "buy" ratings and no "strong buy" or "hold" ratings.
    • The company's risk profile is low in terms of liquidity and dilution, but its long-term viability depends on successful clinical development.
    • The company's valuation is premium relative to book value, with a price-to-book ratio of 4.38.

    Bull / Bear case

    Generated · model-assisted
    — missing data

    In focus — financials by report

    Valuation

    Market price
    $2,06
    Market cap
    $73.8M
    Enterprise value
    $54.3M
    P/E
    Non-GAAP P/E
    EV / Revenue
    EV / Op income
    EV / OCF
    P / B
    4.4x
    P / Tangible book
    4.4x
    Tangible book
    $16.9M
    Net cash
    $19.5M
    Current ratio
    5.8
    Debt / equity
    0.0
    ROA
    -1.4%
    ROE
    -1.7%
    Cash conversion
    89.0%
    CapEx / revenue
    SBC / revenue
    Dilution ratio
    0.0%

    Revenue by segment

    Market share

    — missing data

    Business relationships

    — missing data

    Supply chain

    — missing data

    Peer comparison

    — missing data

    Market position

    Stress test

    — missing data

    Predictor forecast

    Next quarternear-term
    Earnings · next quarterconf 45 %
    EPS
    Consensus EPS
    -1,27
    Predicted surprise
    +0,00
    Beat probability
    45 %
    Analysts
    4
    Other metrics
    Revenue
    no estimate
    Segment revenue
    no estimate
    Margin
    no estimate
    Segment margin
    no estimate
    as of 2026-05-16 · Earnings Surprise V1
    Period note: consensus is not fiscal-period-aligned at source — read as consensus vs the last reported actual, not a calibrated same-quarter surprise.
    Full fiscal year~1 year ahead
    Full fiscal year · our forecast vs guidance vs consensus
    MetricOur forecastGuidanceConsensus
    EPSno estimateno estimate-1,27
    Revenueno estimateno estimate0 USD
    Operating incomeno estimateno estimate-44,2M USD
    Full-year consensus mean (period as reported by source) · consensus in USD. Company-level full-year forecast and management guidance are not yet modelled at scale — shown as "no estimate", never inferred.
    Probabilistic model output — not investment advice. · generated 2026-08-04

    Options

    — missing data

    Short squeeze

    — missing data

    Earnings-call key lines

    — missing data

    Consensus distribution

    sell-side coverage
    Recommendation distribution4 analysts
    Strong buy0
    Buy4
    Hold0
    Sell0
    Strong sell0
    12-month price target$15,67 · Median $17,00
    Low $10,00High $20,00
    Operating income · consensus-44,2M USD
    EPS surprise
    −10,2 %
    reported vs consensus · miss

    Estimate revisions

    consensus EPS · 26-week trend
    — missing data

    Sell-side observations

    Low$10,00
    Mean$15,67
    Median$17,00
    High$20,00
    Spot$2,06
    +660.5 %implied to mean12-month sell-side price targets · ▲ spot

    Themes

    — missing data

    ESG

    — missing data

    Risk factors

    Dilution riskLow
    Liquidity riskLow
    Filing-based flags
    • No immediate filing-based liquidity or dilution flags were detected.

    Benchmarks vs cohort

    ROE-171,2 %Bottom quartile
    D/E0,00Above median
    Cash Conv0,89Above median

    Corporate actions / M&A

    — missing data

    FX exposure

    — missing data

    Comparable transactions

    — missing data

    Derivatives & instruments

    Derivative transactions

    Net disposed 7 142 sh1 exercises1 insiders
    • Bruck ClaudineDirector · Option → Common StockDisposed 7 142 @ $0,14exercise · 2025-09-10

    Actions

    Ask Handelsavisen

    — missing data
    Data sources
    • Market data
    • Market data cache
    • Issuer disclosures
    • Public news
    • Earnings transcripts
    • Consensus estimates
    • ESG data
    How metrics are computed
    • Return On Equity
      net_income / total_equity
    • Price To Book
      market_price / (adjusted_book_value / shares_outstanding_diluted)
    • Dilution Ratio
      (shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
    • Market Price
      input from market-data provider (delayed close or quote-shim mid)
    • Market Cap
      market_price * shares_outstanding_diluted
    • Net Cash
      cash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
    Source documents
    • Annovis Bio Inc Market data — financials · 2026-05-27
    • Annovis Bio Inc Market data — analyst estimates · 2026-05-27

    Ownership & reference

    Top holders

    • Vanguard Capital Management, LLCInvestment Managers · as of 2025-12-310,00 %$3M
    • Northern Trust Investments, Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • Geode Capital Management, L.L.C.Investment Managers · as of 2026-03-310,00 %$1M
    • BlackRock Institutional Trust Company, N.A.Investment Managers · as of 2024-06-300,00 %$1M
    • UBS Financial Services, Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • Wells Fargo AdvisorsBrokerage Firms · as of 2026-03-310,00 %$0M
    • Bank of New York Mellon CorpInstitutional Investor · as of 2026-03-310,00 %$0M
    • State Street Investment Management (US)Investment Managers · as of 2026-03-310,00 %$0M
    • Morgan Stanley Smith Barney LLCInvestment Managers · as of 2026-03-310,00 %$0M
    • PNC Investments LLCInvestment Managers · as of 2026-03-310,00 %$0M

    Insider activity

    Net buying15 buys · 0 sellsnet $4,3M3 insiders · last 365d
    • Hoffman Michael BDirector · Common StockBought 2 562 @ $1,75$4K · 2026-05-20
    • Hoffman Michael BDirector · Common StockBought 18 849 @ $1,80$34K · 2026-05-20
    • Hoffman Michael BDirector · Common StockBought 54 933 @ $1,90$104K · 2026-05-20
    • Hoffman Michael BDirector · Common StockBought 713 800 @ $2,10$1,5M · 2026-04-02
    • Hoffman Michael BDirector · Common StockBought 30 000 @ $4,34$130K · 2025-12-08
    • Hoffman Michael BDirector · Common StockBought 15 000 @ $4,24$64K · 2025-12-08
    • Hoffman Michael BDirector · Common StockBought 415 @ $4,14$2K · 2025-11-24
    • Hoffman Michael BDirector · Common StockBought 1 489 @ $4,13$6K · 2025-11-24
    • Hoffman Michael BDirector · Common StockBought 9 200 @ $3,85$35K · 2025-11-24
    • Hoffman Michael BDirector · Common StockBought 28 096 @ $4,15$117K · 2025-11-24
    • Hoffman Michael BDirector · Common StockBought 10 000 @ $3,49$35K · 2025-11-21
    • Hoffman Michael BDirector · Common StockBought 10 000 @ $3,50$35K · 2025-11-21
    • Hoffman Michael BDirector · Common StockBought 15 000 @ $2,11$32K · 2025-11-14
    • Hoffman Michael BDirector · Common StockBought 975 610 @ $2,05$2,0M · 2025-10-28
    • Maccecchini Maria-LuisaDirector, President & CEO · Common StockBought 97 561 @ $2,05$200K · 2025-10-28
    • Bruck ClaudineDirector · Common StockOther 7 142 @ $0,14$1 000 · 2025-09-10
    • Hoffman Michael BDirector · Common StockOther 5 000 @ $2,29$11K · 2025-08-29
    • Hoffman Michael BDirector · Common StockOther 5 000 @ $2,28$11K · 2025-08-29
    • Hoffman Michael BDirector · Common StockOther 5 000 @ $2,30$12K · 2025-08-29
    • Hoffman Michael BDirector · Common StockOther 1 100 @ $2,57$3K · 2025-08-19
    • Hoffman Michael BDirector · Common StockOther 5 283 @ $2,59$14K · 2025-08-19
    • Hoffman Michael BDirector · Common StockOther 5 545 @ $2,58$14K · 2025-08-19
    • Hoffman Michael BDirector · Common StockOther 6 717 @ $2,60$17K · 2025-08-19

    Short positioning

    5.5Mshares short+12.0% vs prior
    5.05days to cover
    48.9%short of daily vol
    528fails-to-deliver
    as of 2026-07-15 · short-interest report (free)

    Geographic breakdown

    — missing data
    Listings · one canonical issuer all listings resolve to the canonical
    ANVS.KCanonical
    NYSE · USD

    Intel & risk

    PredictorBeat prob45 %Surprise+0,00Full forecast →
    peak dispatch · —
    OSINT findings
    Dilution riskLow
    Liquidity riskLow
    No immediate filing-based liquidity or dilution flags were detected.

    Evidence & claims

    From filings & derived data
    • Return on equity (FY 2025-12-31): -171.2%Derived (calculated)
    • Operating income (YoY) (2025-12-31 vs 2024-12-31): -11.2%Derived (calculated)
    • R&D expense (YoY) (2025-12-31 vs 2024-12-31): 26.1%Derived (calculated)
    • Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -17.0%Derived (calculated)
    • Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): 85.1%Derived (calculated)
    • EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 39.4%Derived (calculated)
    • Net income (YoY) (2025-12-31 vs 2024-12-31): -17.3%Derived (calculated)
    • Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): 81.0%Derived (calculated)
    • Total assets (YoY) (2025-12-31 vs 2024-12-31): 51.4%Derived (calculated)
    • Debt-to-equity (FY 2025-12-31): 0.25xDerived (calculated)
    • Return on assets (FY 2025-12-31): -136.9%Derived (calculated)
    • EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 30.7%Derived (calculated)
    • Total liabilities (YoY) (2025-12-31 vs 2024-12-31): -8.4%Derived (calculated)
    • EPS (basic) (annual): USD-PER-SHARES -1SEC XBRL filing
    • Revenue (annual): USD 0SEC XBRL filing
    • Cash & equivalents (annual): USD 19.53MSEC XBRL filing
    • Net income (annual): USD -28.85MSEC XBRL filing
    • Total operating expenses (annual): USD 29.7MSEC XBRL filing
    • Total assets (annual): USD 21.08MSEC XBRL filing
    • Operating cash flow (annual): USD -25.62MSEC XBRL filing
    • Current liabilities (annual): USD 3.64MSEC XBRL filing
    • Shares outstanding (annual): 27.2MSEC XBRL filing
    • Shareholders' equity (annual): USD 16.85MSEC XBRL filing
    • Total liabilities (annual): USD 4.23MSEC XBRL filing
    Showing 24 of 60 surfaced claims.
    Atomic claims from regulatory filings and derived calculations. Provenance shown as source kind only.

    The Thread

    Everything we know, in order
    2026-10-28EVENTUpcomingQ3 2026 earnings (expected) estimated date
    2026-06-30 03:38 UTCEARNINGSUpcomingForecast: earnings_forecast (90d)
    2026-06-17FILINGFORM 8-K →
    2026-05-20 00:00 UTCINSIDER3 insider transactions — 2026-05 · net buy $143k
    2026-05-20FILINGFORM 8-K →
    2026-05-20FILING424B5 filing →
    2026-05-20INSIDERHoffman Michael B bought 2.6k sh — Director ~$4k
    2026-05-20INSIDERHoffman Michael B bought 18.8k sh — Director ~$34k
    2026-05-20INSIDERHoffman Michael B bought 54.9k sh — Director ~$104k
    2026-05-19FILING424B5 filing →
    2026-05-15FILING10-Q filing →
    2026-05-15FILINGFORM 8-K →
    2026-04-30FILINGFORM DEF 14A →
    2026-04-10FILINGFORM 8-K →
    2026-04-09FILING424B5 filing →
    2026-04-02 00:00 UTCINSIDER1 insider transaction — 2026-04 · net buy $1.5M
    2026-04-02INSIDERHoffman Michael B bought 713.8k sh — Director ~$1.50M
    2026-03-25FILINGFORM 8-K →
    2026-03-16FILINGFORM 8-K →
    2026-03-13FILING10-K filing →
    2025-12-08 00:00 UTCINSIDER2 insider transactions — 2025-12 · net buy $194k
    2025-12-08INSIDERHoffman Michael B bought 30.0k sh — Director ~$130k
    2025-12-08INSIDERHoffman Michael B bought 15.0k sh — Director ~$64k
    2025-11-24 00:00 UTCINSIDER7 insider transactions — 2025-11 · net buy $261k
    2025-11-24INSIDERHoffman Michael B bought 415 sh — Director ~$2k
    2025-11-24INSIDERHoffman Michael B bought 1.5k sh — Director ~$6k
    2025-11-24INSIDERHoffman Michael B bought 9.2k sh — Director ~$35k
    2025-11-24INSIDERHoffman Michael B bought 28.1k sh — Director ~$117k
    2025-11-21INSIDERHoffman Michael B bought 10.0k sh — Director ~$35k
    2025-11-14INSIDERHoffman Michael B bought 15.0k sh — Director ~$32k
    2025-10-28 00:00 UTCINSIDER2 insider transactions — 2025-10 · net buy $2.2M
    2025-10-28INSIDERHoffman Michael B bought 975.6k sh — Director ~$2.00M
    2025-10-28INSIDERMaccecchini Maria-Luisa bought 97.6k sh — Director, President & CEO ~$200k
    2025-09-10 00:00 UTCINSIDER2 insider transactions — 2025-09 1 derivative
    2025-09-10INSIDERBruck Claudine transacted 7.1k sh — Director ~$1k
    2025-09-10INSIDERBruck Claudine disposed of 7.1k sh Option — Director
    2025-08-29 00:00 UTCINSIDER7 insider transactions — 2025-08
    2025-08-29INSIDERHoffman Michael B transacted 5.0k sh — Director ~$11k
    2025-08-19INSIDERHoffman Michael B transacted 1.1k sh — Director ~$3k
    2025-08-19INSIDERHoffman Michael B transacted 5.3k sh — Director ~$14k
    Showing the 40 most recent of 43 entries.
    The entity's full life in the product — typed, chronological, joined across Newspaper, Platform and Data. Our memory, made visible.
    Sources filings · IR · transcripts · market data · tier hybrid · as of 2026-08-04 Market data · Issuer disclosures · Public news · Earnings transcripts · Consensus estimates · ESG data Premium coverage