Annovis Bio Inc
Annovis Bio Inc is a clinical-stage biopharmaceutical company focused on the development of therapies for neurodegenerative diseases, including Alzheimer's and Parkinson's.
Business. Annovis Bio Inc (ANVS.K) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the New York Stock Exchange. Specific details regarding operating segments and geographic revenue mix are not available.
Analyst recommendations
4 analysts · consensus BuyAt a glance
What drives this business
The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
News & coverage
0Sector rotation
Developing storylines
Analysis
AI analysisOpportunity
Upcoming catalysts
Scheduled public events. Informational only — not investment advice.
- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
Annovis Bio Inc (ANVS.K) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the New York Stock Exchange. Specific details regarding operating segments and geographic revenue mix are not available.
Annovis Bio Inc has a market capitalization of $73.8 million and a price-to-book ratio of 4.38, indicating a premium valuation relative to its book value. The company holds $19.5 million in cash and equivalents, with no long-term debt, and a current ratio of 5.8, suggesting strong short-term liquidity. However, the company reported a net loss of $28.9 million and an operating loss of $29.7 million, with negative returns on equity (-17.1%) and assets (-13.7%).
The company's financial performance is below the typical metrics for the biotechnology industry, which often includes high R&D expenses and long development cycles. The negative EBITDA of -$1.8 million and the absence of revenue from operations highlight the early-stage nature of its business model. The company's capital structure is entirely equity-based, with no debt, and a debt-to-equity ratio of 0.0.
Annovis Bio Inc operates in a single business segment focused on neurodegenerative disease therapies. The company's geographic exposure is not disclosed in the available data, but as a clinical-stage biopharmaceutical firm, it likely targets global markets for its drug candidates. The company's revenue concentration is not disclosed, but as a pre-revenue entity, it is not yet generating product-based income.
The company is in a high-growth phase, with no revenue to date and a focus on clinical development. Analysts have assigned a mean price target of $15.67 and a median of $17.00, with four "buy" ratings and no "strong buy" or "hold" ratings. The company's outlook for the current fiscal year is not disclosed, but the absence of revenue and ongoing losses suggest a continuation of investment in R&D and clinical trials.
The company's risk profile is characterized by low liquidity and dilution risk, with no immediate filing-based flags detected. The company has a low dilution risk, with no near-term pressure for additional equity issuance. The absence of long-term debt and the presence of $19.5 million in cash and equivalents provide a buffer against short-term liquidity challenges. However, the company's reliance on equity financing and the absence of revenue expose it to dilution risk in the long term.
Recent events include the publication of analyst price targets and the absence of any significant regulatory or operational filings. The company's focus on clinical development and the absence of revenue suggest that its near-term financial performance will be driven by the progress of its drug candidates through clinical trials.
- Annovis Bio Inc is a clinical-stage biopharmaceutical company with no revenue and ongoing losses.
- The company has strong liquidity with $19.5 million in cash and no debt, but is not yet generating revenue.
- Analysts have assigned a mean price target of $15.67, with four "buy" ratings and no "strong buy" or "hold" ratings.
- The company's risk profile is low in terms of liquidity and dilution, but its long-term viability depends on successful clinical development.
- The company's valuation is premium relative to book value, with a price-to-book ratio of 4.38.
Bull / Bear case
Generated · model-assistedIn focus — financials by report
Valuation
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -1,27 |
| Revenue | —no estimate | —no estimate | 0 USD |
| Operating income | —no estimate | —no estimate | -44,2M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Director · Option → Common StockDisposed 7 142 @ $0,14exercise · 2025-09-10
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Return On Equitynet_income / total_equity
- Price To Bookmarket_price / (adjusted_book_value / shares_outstanding_diluted)
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Market Priceinput from market-data provider (delayed close or quote-shim mid)
- Market Capmarket_price * shares_outstanding_diluted
- Net Cashcash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
- Annovis Bio Inc Market data — financials · 2026-05-27
- Annovis Bio Inc Market data — analyst estimates · 2026-05-27
Ownership & reference
Top holders
- Investment Managers · as of 2025-12-310,00 %$3M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2024-06-300,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$0M
- Brokerage Firms · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
Insider activity
- Director · Common StockBought 2 562 @ $1,75$4K · 2026-05-20
- Director · Common StockBought 18 849 @ $1,80$34K · 2026-05-20
- Director · Common StockBought 54 933 @ $1,90$104K · 2026-05-20
- Director · Common StockBought 713 800 @ $2,10$1,5M · 2026-04-02
- Director · Common StockBought 30 000 @ $4,34$130K · 2025-12-08
- Director · Common StockBought 15 000 @ $4,24$64K · 2025-12-08
- Director · Common StockBought 415 @ $4,14$2K · 2025-11-24
- Director · Common StockBought 1 489 @ $4,13$6K · 2025-11-24
- Director · Common StockBought 9 200 @ $3,85$35K · 2025-11-24
- Director · Common StockBought 28 096 @ $4,15$117K · 2025-11-24
- Director · Common StockBought 10 000 @ $3,49$35K · 2025-11-21
- Director · Common StockBought 10 000 @ $3,50$35K · 2025-11-21
- Director · Common StockBought 15 000 @ $2,11$32K · 2025-11-14
- Director · Common StockBought 975 610 @ $2,05$2,0M · 2025-10-28
- Director, President & CEO · Common StockBought 97 561 @ $2,05$200K · 2025-10-28
- Director · Common StockOther 7 142 @ $0,14$1 000 · 2025-09-10
- Director · Common StockOther 5 000 @ $2,29$11K · 2025-08-29
- Director · Common StockOther 5 000 @ $2,28$11K · 2025-08-29
- Director · Common StockOther 5 000 @ $2,30$12K · 2025-08-29
- Director · Common StockOther 1 100 @ $2,57$3K · 2025-08-19
- Director · Common StockOther 5 283 @ $2,59$14K · 2025-08-19
- Director · Common StockOther 5 545 @ $2,58$14K · 2025-08-19
- Director · Common StockOther 6 717 @ $2,60$17K · 2025-08-19
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Return on equity (FY 2025-12-31): -171.2%Derived (calculated)
- Operating income (YoY) (2025-12-31 vs 2024-12-31): -11.2%Derived (calculated)
- R&D expense (YoY) (2025-12-31 vs 2024-12-31): 26.1%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -17.0%Derived (calculated)
- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): 85.1%Derived (calculated)
- EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 39.4%Derived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): -17.3%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): 81.0%Derived (calculated)
- Total assets (YoY) (2025-12-31 vs 2024-12-31): 51.4%Derived (calculated)
- Debt-to-equity (FY 2025-12-31): 0.25xDerived (calculated)
- Return on assets (FY 2025-12-31): -136.9%Derived (calculated)
- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 30.7%Derived (calculated)
- Total liabilities (YoY) (2025-12-31 vs 2024-12-31): -8.4%Derived (calculated)
- EPS (basic) (annual): USD-PER-SHARES -1SEC XBRL filing
- Revenue (annual): USD 0SEC XBRL filing
- Cash & equivalents (annual): USD 19.53MSEC XBRL filing
- Net income (annual): USD -28.85MSEC XBRL filing
- Total operating expenses (annual): USD 29.7MSEC XBRL filing
- Total assets (annual): USD 21.08MSEC XBRL filing
- Operating cash flow (annual): USD -25.62MSEC XBRL filing
- Current liabilities (annual): USD 3.64MSEC XBRL filing
- Shares outstanding (annual): 27.2MSEC XBRL filing
- Shareholders' equity (annual): USD 16.85MSEC XBRL filing
- Total liabilities (annual): USD 4.23MSEC XBRL filing