Aprea Therapeutics Inc
Aprea Therapeutics Inc is a biotechnology company focused on the development of novel therapies for the treatment of rare and life-threatening diseases, primarily in the field of hematology and oncology.
Business. Aprea Therapeutics Inc (APRE.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.
Analyst recommendations
3 analysts · consensus BuyAt a glance
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The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
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- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
Aprea Therapeutics Inc (APRE.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.
Aprea Therapeutics Inc maintains a strong liquidity position, with cash and equivalents amounting to $32.37 million, significantly exceeding its total liabilities of $2.97 million, resulting in a current ratio of 11.15. The company has no long-term debt, and its debt-to-equity ratio is 0.0, indicating a conservative capital structure. The price-to-book ratio of 0.39 and price-to-tangible-book ratio of 0.39 suggest that the company is trading at a substantial discount to its book value, potentially reflecting market skepticism about its near-term profitability.
The company reported a net loss of $2.81 million and an operating loss of $3.15 million in the latest period, with a return on equity of -9.29% and a return on assets of -8.46%. These metrics indicate that Aprea is not currently generating returns for shareholders and is underperforming relative to the industry's preferred metrics of profitability and capital efficiency. The negative operating and free cash flows (-$3.94 million and -$2.81 million, respectively) further highlight the company's reliance on external financing to fund operations.
Aprea Therapeutics Inc does not disclose segment or geographic revenue breakdowns in its latest financials, making it difficult to assess the concentration of its revenue streams or geographic exposure. However, as a biotechnology firm, it is likely that its operations are concentrated in the United States, where the majority of its research and development activities are conducted.
The company's growth trajectory is uncertain, as it has not provided forward-looking revenue guidance. Analysts have assigned a mean price target of $4.40 and a median price target of $5.00, with a mean recommendation of 1.67 (leaning toward "buy"). These estimates suggest that the market sees potential for upside, but the absence of concrete revenue growth projections makes it difficult to assess the company's long-term viability.
Aprea Therapeutics Inc faces low liquidity and dilution risk, with no immediate filing-based flags detected. The company has a low dilution potential, as the number of basic and diluted shares outstanding is identical, and there is no indication of recent or pending share issuance. However, the company's negative cash flows and lack of profitability could necessitate future equity or debt financing, which may introduce dilution risk.
There are no recent filings or transcripts provided in the available data to assess Aprea's strategic direction or operational developments. The company's focus on clinical-stage drug development suggests that its future performance will depend on the success of its pipeline and the ability to secure regulatory approvals.
- Aprea Therapeutics Inc has a strong liquidity position with no long-term debt and a current ratio of 11.15.
- The company is currently unprofitable, with a net loss of $2.81 million and negative returns on equity and assets.
- The company's valuation is significantly discounted, with a price-to-book ratio of 0.39.
- Analysts have a generally positive outlook, with a mean price target of $4.40 and a median price target of $5.00.
- Aprea faces no immediate liquidity or dilution risks, but its long-term viability depends on the success of its drug development pipeline.
Bull / Bear case
Generated · model-assistedIn focus — financials by report
Revenue $3.3k, −98,4% YoY; Operating income +18,1% YoY.
- ▍Revenue $3.3k, −98,4% YoY
- ▍Operating income +18,1% YoY
- ▍Net income +15,2% YoY
- ▍Free cash flow +15,2% YoY
- ▍Net margin -73521.9%
Revenue $1.9k, −99,5% YoY; Operating income +23,9% YoY.
- ▍Revenue $1.9k, −99,5% YoY
- ▍Operating income +23,9% YoY
- ▍Net income +21,4% YoY
- ▍Free cash flow +21,5% YoY
- ▍Net margin -160670.8%
Revenue $118.1k, −79,0% YoY; Operating income +11,9% YoY.
- ▍Revenue $118.1k, −79,0% YoY
- ▍Operating income +11,9% YoY
- ▍Net income +6,7% YoY
- ▍Free cash flow +6,9% YoY
- ▍Net margin -2742.2%
Revenue $205.8k; Operating income -$3.2M.
- ▍Revenue $205.8k
- ▍Operating income -$3.2M
- ▍Net margin -1406.5%
Revenue $354.6k; Operating income -$4.1M.
- ▍Revenue $354.6k
- ▍Operating income -$4.1M
- ▍Net margin -1067.0%
Revenue $561.6k; Operating income -$3.8M.
- ▍Revenue $561.6k
- ▍Operating income -$3.8M
- ▍Net margin -617.9%
Revenue $380.6k; Operating income -$3.1M.
- ▍Revenue $380.6k
- ▍Operating income -$3.1M
- ▍Net margin -738.4%
Revenue $285.8k, −81,0% YoY; Operating income +7,6% YoY.
- ▍Revenue $285.8k, −81,0% YoY
- ▍Operating income +7,6% YoY
- ▍Net income +2,8% YoY
- ▍Free cash flow +2,9% YoY
- ▍Net margin -4409.1%
Revenue $1.5M, +157,6% YoY; Operating income +7,5% YoY.
- ▍Revenue $1.5M, +157,6% YoY
- ▍Operating income +7,5% YoY
- ▍Net income +9,3% YoY
- ▍Free cash flow +9,9% YoY
- ▍Net margin -862.4%
Revenue $583.2k; Operating income +86,4% YoY.
- ▍Revenue $583.2k
- ▍Operating income +86,4% YoY
- ▍Net income +87,3% YoY
- ▍Free cash flow +87,2% YoY
- ▍Net margin -2449.6%
Operating income −202,8% YoY; Net income −203,4% YoY.
- ▍Operating income −202,8% YoY
- ▍Net income −203,4% YoY
- ▍Free cash flow −203,5% YoY
Operating income -$37.4M.
- ▍Operating income -$37.4M
Valuation TTM
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -0,72 |
| Revenue | —no estimate | —no estimate | 0 USD |
| Operating income | —no estimate | —no estimate | -14,3M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Director · Stock Options (Right to Buy) → Common StockAcquired 12 555 @ $0,73grant · 2026-06-16
- Director · Stock Options (Right to Buy) → Common StockAcquired 12 555 @ $0,73grant · 2026-06-16
- Director · Stock Options (Right to Buy) → Common StockAcquired 12 555 @ $0,73grant · 2026-06-16
- Director · Stock Options (Right to Buy) → Common StockAcquired 12 555 @ $0,73grant · 2026-06-16
- Director · Stock Options (Right to Buy) → Common StockAcquired 12 555 @ $0,73grant · 2026-06-16
- Director · Stock Options (Right to Buy) → Common StockAcquired 12 555 @ $0,73grant · 2026-06-16
- Director · Stock Options (Right to Buy) → Common StockAcquired 12 555 @ $0,73grant · 2026-06-16
- Director · Stock Options (Right to Buy) → Common StockAcquired 12 555 @ $0,73grant · 2026-06-16
- Director · Pre-Funded Warrant → Common StockAcquired 123 915 @ $0,00purchase · 2026-03-31
- SrVP/CFO/Prin Fin & Acct Ofcr · Pre-Funded Warrant → Common StockAcquired 30 978 @ $0,00purchase · 2026-03-31
- SrVP/CFO/Prin Fin & Acct Ofcr · Common Warrant → Common StockAcquired 30 978 @ $0,68purchase · 2026-03-31
- Director · Common Warrant → Common StockAcquired 123 915 @ $0,68purchase · 2026-03-31
- Director, President/CEO · Stock Options (Right to Buy) → Common StockAcquired 80 700 @ $0,77grant · 2026-03-12
- SrVP/CFO/Prin Fin & Acct Ofcr · Stock Options (Right to Buy) → Common StockAcquired 40 380 @ $0,77grant · 2026-03-12
- SrVP/CFO/Prin Fin & Acct Ofcr · Common Warrant → Common StockAcquired 5 700 @ $0,77purchase · 2026-01-30
- Director, President/CEO · Common Warrant → Common StockAcquired 28 100 @ $0,77purchase · 2026-01-30
- Director, President/CEO · Pre-Funded Warrant → Common StockAcquired 21 459 @ $0,00purchase · 2025-12-10
- Director · Common Warrant → Common StockAcquired 21 459 @ $1,04purchase · 2025-12-10
- SrVP/CFO/Prin Fin & Acct Ofcr · Common Warrant → Common StockAcquired 5 000 @ $1,04purchase · 2025-12-10
- Director, President/CEO · Common Warrants → Common StockAcquired 21 459 @ $1,04purchase · 2025-12-10
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Return On Equitynet_income / total_equity
- Price To Bookmarket_price / (adjusted_book_value / shares_outstanding_diluted)
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Market Priceinput from market-data provider (delayed close or quote-shim mid)
- Market Capmarket_price * shares_outstanding_diluted
- Ev To Revenueenterprise_value / revenue
- Aprea Therapeutics Inc Market data — financials · 2026-05-27
- Aprea Therapeutics Inc Market data — analyst estimates · 2026-05-27
- Aprea Therapeutics Inc Market data — ESG · 2026-05-27
Ownership & reference
Top holders
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2024-06-300,00 %$0M
- Investment Managers · as of 2025-12-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
Insider activity
- Director · Common StockOther 3 135 · 2026-06-16
- Director · Common StockOther 3 135 · 2026-06-16
- Director · Common StockOther 3 135 · 2026-06-16
- Director · Common StockOther 3 135 · 2026-06-16
- Director · Common StockOther 3 135 · 2026-06-16
- Director · Common StockOther 3 135 · 2026-06-16
- Director · Common StockOther 3 135 · 2026-06-16
- Director · Common StockOther 3 135 · 2026-06-16
- SrVP/CFO/Prin Fin & Acct Ofcr · Common StockOther 10 095 · 2026-03-12
- Director, President/CEO · Common StockOther 20 175 · 2026-03-12
- SrVP/CFO/Prin Fin & Acct Ofcr · Common StockBought 5 700 @ $0,89$5K · 2026-01-30
- Director, President/CEO · Common StockBought 28 100 @ $0,89$25K · 2026-01-30
- SrVP/CFO/Prin Fin & Acct Ofcr · Common StockBought 5 000 @ $1,17$6K · 2025-12-10
- Director · Common StockBought 21 459 @ $1,17$25K · 2025-12-10
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 17.9%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): 4.9%Derived (calculated)
- Total assets (YoY) (2025-12-31 vs 2024-12-31): -33.6%Derived (calculated)
- Return on equity (FY 2025-12-31): -101.3%Derived (calculated)
- Operating income (YoY) (2025-12-31 vs 2024-12-31): 7.6%Derived (calculated)
- Return on assets (FY 2025-12-31): -79.1%Derived (calculated)
- Current ratio (FY 2025-12-31): 5.63xDerived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): 2.8%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): -35.6%Derived (calculated)
- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 17.9%Derived (calculated)
- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): -36.1%Derived (calculated)
- Shares outstanding (annual): 8.19MSEC XBRL filing
- Total assets (annual): USD 15.93MSEC XBRL filing
- Current liabilities (annual): USD 2.76MSEC XBRL filing
- Operating cash flow (annual): USD -12.89MSEC XBRL filing
- Current assets (annual): USD 15.56MSEC XBRL filing
- EPS (basic) (annual): USD-PER-SHARES -2SEC XBRL filing
- Total operating expenses (annual): USD 13.52MSEC XBRL filing
- EPS (diluted) (annual): USD-PER-SHARES -2SEC XBRL filing
- Shareholders' equity (annual): USD 12.44MSEC XBRL filing
- Cash & equivalents (annual): USD 14.6MSEC XBRL filing
- Operating income (annual): USD -13.23MSEC XBRL filing
- Net income (annual): USD -12.6MSEC XBRL filing
- EPS (diluted) (YoY) (2024-12-31 vs 2023-12-31): 40.5%Derived (calculated)