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INDICATIVE · SAMPLE DATA
ATYR$0.9258

aTyr Pharma Inc

Biotechnology & Medical ResearchVerified

aTyr Pharma maintains a strong liquidity position with a current ratio of 5.3, supported by $10.74 million in cash and equivalents and total assets of $93.00 million. The company's debt-to-equity ratio is 0.01, indicating minimal leverage, and its market cap of $90.38 million is modest relative to its book value of $67.48 million, as reflected in a price-to-book ratio of 1.34. The company is currently unprofitable, with a net loss of $74.12 million and an operating loss of $77.63 million. Return on equity is -109.84%, and return on assets is -7.97%, both significantly below industry norms for biotechnology firms. The enterprise value to revenue ratio of 423.84 suggests a high valuation relative to its current revenue of $190.00 million, which is driven by a small market cap and no debt. aTyr Pharma's revenue is concentrated in a single business segment, with no disclosed geographic diversification. The company's operations are entirely focused on the development of therapeutic candidates, with no revenue from commercialized products. This concentration increases exposure to clinical trial outcomes and regulatory delays. The company's growth trajectory is uncertain, with no revenue growth reported in the latest period. Analysts have issued a wide range of price targets, from $1.00 to $20.00, with a mean of $6.36 and a median of $1.00. The mean recommendation score of 2.60 suggests a mixed outlook, with seven "hold" ratings and only three "buy" or "strong buy" ratings. aTyr Pharma faces significant financial risk due to its negative operating and free cash flows, which are -$61.99 million and -$73.50 million, respectively. The company has no immediate liquidity or dilution flags, but its capital expenditures of -$77,000 suggest minimal investment in infrastructure. The risk assessment indicates low dilution potential, but the absence of positive cash flows raises concerns about long-term sustainability. Recent filings and transcripts have not revealed any major events or strategic shifts. The company continues to focus on its clinical pipeline, with no new product launches or partnerships disclosed in the latest period. The lack of recent developments may contribute to the wide dispersion in analyst price targets.

30-day price · ATYR-0.32 (-38.8%)
Low$0.40High$1.05Close$0.50As of17 May, 00:00 UTC
Profile
CompanyaTyr Pharma Inc
TickerATYR.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. aTyr Pharma Inc is a biotechnology company focused on the discovery and development of novel therapeutics for immune and inflammatory diseases, with a pipeline including clinical-stage programs in dermatology and oncology.

Classification. aTyr Pharma is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a confidence level of 0.92.

aTyr Pharma maintains a strong liquidity position with a current ratio of 5.3, supported by $10.74 million in cash and equivalents and total assets of $93.00 million. The company's debt-to-equity ratio is 0.01, indicating minimal leverage, and its market cap of $90.38 million is modest relative to its book value of $67.48 million, as reflected in a price-to-book ratio of 1.34. The company is currently unprofitable, with a net loss of $74.12 million and an operating loss of $77.63 million. Return on equity is -109.84%, and return on assets is -7.97%, both significantly below industry norms for biotechnology firms. The enterprise value to revenue ratio of 423.84 suggests a high valuation relative to its current revenue of $190.00 million, which is driven by a small market cap and no debt. aTyr Pharma's revenue is concentrated in a single business segment, with no disclosed geographic diversification. The company's operations are entirely focused on the development of therapeutic candidates, with no revenue from commercialized products. This concentration increases exposure to clinical trial outcomes and regulatory delays. The company's growth trajectory is uncertain, with no revenue growth reported in the latest period. Analysts have issued a wide range of price targets, from $1.00 to $20.00, with a mean of $6.36 and a median of $1.00. The mean recommendation score of 2.60 suggests a mixed outlook, with seven "hold" ratings and only three "buy" or "strong buy" ratings. aTyr Pharma faces significant financial risk due to its negative operating and free cash flows, which are -$61.99 million and -$73.50 million, respectively. The company has no immediate liquidity or dilution flags, but its capital expenditures of -$77,000 suggest minimal investment in infrastructure. The risk assessment indicates low dilution potential, but the absence of positive cash flows raises concerns about long-term sustainability. Recent filings and transcripts have not revealed any major events or strategic shifts. The company continues to focus on its clinical pipeline, with no new product launches or partnerships disclosed in the latest period. The lack of recent developments may contribute to the wide dispersion in analyst price targets.
Key takeaways
  • aTyr Pharma has strong liquidity but is currently unprofitable with significant negative cash flows.
  • The company's valuation is highly speculative, with an EV/revenue ratio of 423.84 and no commercialized products.
  • Analysts are divided on the stock, with a mean price target of $6.36 but a median of $1.00.
  • The company's business is entirely dependent on clinical trial success, with no geographic or segment diversification.
  • Despite low dilution risk, the company's financial structure is vulnerable to prolonged negative cash flows.
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  • ## RATIONALES
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Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$190.0k
Gross profit
Operating income-$77.6M
Net income-$74.1M
R&D
SG&A
D&A
SBC
Operating cash flow-$62.0M
CapEx-$77.0k
Free cash flow-$73.5M
Total assets$93.0M
Total liabilities$25.5M
Total equity$67.5M
Cash & equivalents$10.7M
Long-term debt$889.0k
Valuation
Market price$0.92
Market cap$90.4M
Enterprise value$80.5M
P/E
Reported non-GAAP P/E
EV/Revenue423.8
EV/Op income
EV/OCF
P/B1.3
P/Tangible book1.3
Tangible book$67.5M
Net cash$9.9M
Current ratio5.3
Debt/Equity0.0
ROA-79.7%
ROE-1.1%
Cash conversion84.0%
CapEx/Revenue-40.5%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 693 companies
MetricATYRActivity
Op margin-40856.3%2.4% medp25 -91.8% · p75 12.5%bottom quartile
Net margin-39009.5%1.2% medp25 -98.4% · p75 10.4%bottom quartile
Gross margin45.6% medp25 29.8% · p75 66.7%
CapEx / revenue-40.5%-5.2% medp25 -15.8% · p75 -1.7%bottom quartile
Debt / equity1.0%9.3% medp25 0.1% · p75 43.8%below median
Observations
IR observations
Mean price target6.36 USD
Median price target1.00 USD
High price target20.00 USD
Low price target1.00 USD
Mean recommendation2.60 (1=strong buy, 5=strong sell)
Strong-buy count1.00
Buy count2.00
Hold count7.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-0.60 USD
Last actual EPS-0.80 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod financials
no public URL
2026-05-16 23:55 UTC#788cda14
Source: analysis-pipeline (hybrid)Generated: 2026-05-27 10:19 UTCJob: edb33dc9