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AYTU.O NASDAQ Diversified Pharmaceuticals

Aytu Biopharma Inc

$2,25
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1D5D1M3M6MYTD1Y5YMax
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Mcap
24,1M USD
P/E
EV / Rev
0,3x
Div yield
Op margin
-11,4 %
ROE
-9,4 %
Net margin
-20,6 %
Debt / equity
0,54
Beta
52w range
Volume
4
Day range
Prev close
$2,18
Open
Next earnings
2026-08-09
Ex-dividend
TR 1Y
About

Aytu Biopharma Inc is a specialty pharmaceutical company focused on the development, acquisition, and commercialization of branded and generic prescription pharmaceutical products in the United States.

Business. Aytu Biopharma Inc (AYTU.O) is a pharmaceutical company engaged in the research and development of therapeutic products. The firm operates within the Healthcare sector, specifically focusing on pharmaceuticals and medical research activities. It is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. The company does not disclose specific operating segments or geographic revenue breakdowns in the provided data.

Classification99 %
SectorHealth Care
Industry groupDiversified Pharmaceuticals
Generated · model-assisted
Sell-side consensus
BUY3 analysts
3 buy0 hold0 sell
Avg 12m price target9,33

Analyst recommendations

3 analysts · consensus Buy
Buy3
Hold0
Sell0
12-month price target
9,33
Consensus of sell-side coverage.
Upcoming events
  • EarningsFY 2026 earnings (expected)2026-08-09 · estimated
See all catalysts →

At a glance

Score
not yet scored
Valuation
valuation pending
Analysts
Buy
3 analysts · indicative
Ownership
Dimensional Fund Advisors, L.P.
largest disclosed fund holder
Profitability
-9,4 %
return on equity
Quality
not yet scored

What drives this business

The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.

— missing data

News & coverage

0
  • No recent newsroom coverage mentioning AYTU.
  • Sector rotation

    Sector1D1Mvs mkt
    Materials+2,3 %+6,6 %+1,7 %
    Communication Services+2,2 %−5,5 %+1,6 %
    Energy+0,6 %+3,3 %+0,0 %
    Health Care · THIS SECTOR+0,6 %−0,8 %+0,0 %
    Information Technology+0,6 %+6,7 %+0,0 %
    Consumer Discretionary+0,4 %+7,6 %−0,2 %
    Financials−0,3 %−2,8 %−0,9 %
    Consumer Staples−0,4 %+2,5 %−1,0 %
    Real Estate−0,7 %+10,9 %−1,3 %
    Industrials−1,9 %−3,1 %−2,5 %
    Utilities−1,9 %+28,2 %−2,5 %

    Developing storylines

    No tracked sagas currently linked to AYTU.O. Browse all sagas →

    Analysis

    AI analysis
    Generated · analysis pipeline · tier hybrid · as of 2026-08-04 ↑ At a glance

    Opportunity

    — missing data

    Upcoming catalysts

    Scheduled public events. Informational only — not investment advice.

    • Company
    • EarningsFY 2026 earnings (expected)2026-08-09 · estimated
    • Macro
    • Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
    • Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
    • Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
    • Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
    • Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
    • Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
    • Macro & political
    • ElectionSE Swedish Election2026-09-14 · SE
    • ElectionUS U.S. Midterms2026-11-03 · US
    • ElectionFR French Legislative2027-06-01 · FR

    Pre-earnings brief

    — missing data

    Signals & dispatch

    peak dispatch · —

    Composite-score breakdown

    Synthesis

    Business

    Aytu Biopharma Inc (AYTU.O) is a pharmaceutical company engaged in the research and development of therapeutic products. The firm operates within the Healthcare sector, specifically focusing on pharmaceuticals and medical research activities. It is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. The company does not disclose specific operating segments or geographic revenue breakdowns in the provided data.

    Classification99 %
    SectorHealth Care
    Industry groupDiversified Pharmaceuticals
    AI synthesis
    GENERATED

    Aytu Biopharma Inc has a market price of $2.27, with a market capitalization of $24.36 million, and a price-to-book ratio of 0.79, indicating that the company is trading at a discount to its book value. The company's liquidity position is weak, as evidenced by a current ratio of 0.85, suggesting that it may struggle to meet its short-term obligations with its current assets. The company's free cash flow is negative at -$474,000, and its operating cash flow is also negative at -$600,000, indicating that it is not generating sufficient cash from operations to sustain its activities.

    The company's profitability is underperforming, with a return on equity of -9.38% and a return on assets of -2.24%, both of which are negative and significantly below the industry median for pharmaceutical companies. The company's operating income is negative at -$1.6 million, and its net income is also negative at -$2.9 million, indicating that it is not currently profitable. The gross profit margin is 74.0%, which is relatively high, but the company's operating and net margins are negative, suggesting that it is not effectively managing its operating expenses.

    Aytu Biopharma Inc does not disclose segment or geographic revenue data in the provided financial snapshot, so it is not possible to assess the concentration of its revenue across different business lines or regions. However, the company's operations are primarily focused on the United States, as it is a specialty pharmaceutical company that commercializes products in the U.S..

    The company's growth trajectory is uncertain, as it is currently reporting negative operating and net income. The provided financial data does not include specific outlook figures for the current or next fiscal year, so it is not possible to quantify the expected growth or decline in revenue. The company's liquidity and profitability challenges suggest that it may face headwinds in achieving sustainable growth in the near term.

    The risk assessment indicates that Aytu Biopharma Inc has low liquidity and low dilution risk, with no immediate filing-based liquidity or dilution flags detected. The company's debt-to-equity ratio is 0.54, which is relatively low, but its negative operating cash flow and free cash flow suggest that it may need to rely on external financing to fund its operations. The company's dilution potential is low, and no adjustments have been applied to its valuation metrics.

    There are no recent events or filings mentioned in the provided data that would indicate significant changes in the company's operations or financial position. The company's financial performance and risk profile suggest that it is in a challenging position, and investors should closely monitor its ability to improve its profitability and liquidity.

    Key takeaways
    • Aytu Biopharma Inc is trading at a discount to its book value, with a price-to-book ratio of 0.79.
    • The company is not currently profitable, with a negative return on equity of -9.38% and a negative return on assets of -2.24%.
    • Aytu Biopharma Inc has a weak liquidity position, as indicated by a current ratio of 0.85 and negative operating and free cash flows.
    • The company's debt-to-equity ratio is 0.54, which is relatively low, but its negative cash flows suggest potential financing needs.
    • Analysts have a mixed outlook, with a mean price target of $9.33 and a median price target of $7.00, but no strong buy recommendations.

    Bull / Bear case

    Generated · model-assisted
    BULL CASE · 4

    Analysts project 327% upside to a mean price target of $9.33, signaling strong market optimism for future growth.

    Net income improved 14.4% year-over-year to a loss of $13.6 million, indicating a trajectory toward profitability.

    The company maintains a low debt-to-equity ratio of 0.67, suggesting manageable leverage relative to its equity base.

    Dilution and liquidity risks are assessed as low, providing a stable capital structure for ongoing operations.

    BEAR CASE · 2

    The company faces high credit risk, which could impair its ability to secure favorable financing terms in the future.

    Revenue growth stagnated with a 4-year CAGR of only 0.3%, suggesting limited top-line expansion potential.

    In focus — financials by report

    Quarterly
    Annual
    QUARTERLYFiled 2026-02-03
    Q4 2025 · Quarter highlights
    Open report →

    Revenue $15.2M, −6,5% YoY; Operating income −16,2% YoY.

    Revenue$15.2M−6,5 % YoY
    Operating income-$2.0M−16,2 % YoY
    Net income-$10.6M−1 443,2 % YoY
    Free cash flow-$9.7M−586,3 % YoY
    EPS
    Operating cash flow$3.1M+78,2 % YoY
    Financials
    Income statement
    Revenue$15.2M
    Gross profit$9.6M
    Operating income-$2.0M
    Net income-$10.6M
    Margins
    Gross margin63.5%
    Operating margin-13.0%
    Net margin-69.8%
    FCF margin-64.1%
    Balance sheet
    Total assets$122.0M
    Total liabilities$107.8M
    Total equity$14.2M
    Cash & equivalents$30.0M
    Long-term debt$20.9M
    Cash flow
    Operating cash flow$3.1M
    CapEx-$17.0k
    Free cash flow-$9.7M
    SBC
    P&L flow · revenue → net income
    Revenue $15.2MOperating costs $17.1MTax $8.6MNet income $10.6M
    Highlights
    • Revenue $15.2M, −6,5% YoY
    • Operating income −16,2% YoY
    • Net income −1 443,2% YoY
    • Free cash flow −586,3% YoY
    • Net margin -69.8%

    Valuation TTM

    Market price
    $2,25
    Market cap
    $24.4M
    Enterprise value
    $21.3M
    P/E
    Non-GAAP P/E
    EV / Revenue
    0.3x
    EV / Op income
    EV / OCF
    P / B
    0.8x
    P / Tangible book
    0.8x
    Tangible book
    $30.8M
    Net cash
    $3.0M
    Current ratio
    0.8
    Debt / equity
    0.5
    ROA
    -2.2%
    ROE
    -9.4%
    Cash conversion
    21.0%
    CapEx / revenue
    SBC / revenue
    Dilution ratio
    0.0%

    Revenue by segment

    Neurology & Psychiatry Medications86,7 %
    low · business_description · 2026-07-04
    Pediatric Medications13,3 %
    low · business_description · 2026-07-04

    Market share

    INDUSTRYSEGMENTCOMPANYHealthcareIndustryDiversified Pharmaceuticals1 042,4B node revenueMCK 38,7%COR 30,8%CAH 21,4%DB 3,4%REGN 1,4%BIIB 0,9%ZTS 0,9%GRFS 0,8%Other 1,7%
    Source: company disclosures · own-taxonomy revenue-covered setAYTU 0,0% · rank #19 of 40

    Business relationships

    — missing data

    Supply chain

    — missing data

    Peer comparison

    Peer comparison8 peers · vs AYTU · multiples and returns
    MC
    MCK
    Mckesson Corp
    $827,14
    102,6B USD
    P/E
    21,2x
    vs self
    Div yield
    0,4 %
    vs self
    ROE
    -219,2 %
    -209,9 vs self
    CO
    COR
    Cencora Inc
    $308,37
    60,2B USD
    P/E
    36,4x
    vs self
    Div yield
    0,8 %
    vs self
    ROE
    45,7 %
    +55,1 vs self
    CA
    CAH
    Cardinal Health Inc
    $235,60
    57,0B USD
    P/E
    36,7x
    vs self
    Div yield
    0,9 %
    vs self
    ROE
    -55,9 %
    -46,5 vs self
    DB
    DB
    DB.V
    P/E
    vs self
    Div yield
    vs self
    ROE
    vs self
    RE
    REGN
    REGENERON PHARMACEUTICALS, INC.
    $757,99
    81,0B USD
    P/E
    15,5x
    vs self
    Div yield
    vs self
    ROE
    14,2 %
    +23,6 vs self
    BI
    BIIB
    BIOGEN INC.
    $201,74
    29,6B USD
    P/E
    21,3x
    vs self
    Div yield
    vs self
    ROE
    7,5 %
    +16,9 vs self
    ZT
    ZTS
    Zoetis Inc
    P/E
    vs self
    Div yield
    vs self
    ROE
    vs self
    GR
    GRFS
    Grifols SA
    $7,86
    P/E
    vs self
    Div yield
    vs self
    ROE
    vs self

    Market position

    Stress test

    — missing data

    Predictor forecast

    Next quarternear-term
    Earnings · next quarterconf 45 %
    EPS
    Consensus EPS
    -1,77
    Predicted surprise
    +0,00
    Beat probability
    45 %
    Analysts
    3
    Other metrics
    Revenue
    no estimate
    Segment revenue
    no estimate
    Margin
    no estimate
    Segment margin
    no estimate
    as of 2026-05-16 · Earnings Surprise V1
    Period note: consensus is not fiscal-period-aligned at source — read as consensus vs the last reported actual, not a calibrated same-quarter surprise.
    Full fiscal year~1 year ahead
    Full fiscal year · our forecast vs guidance vs consensus
    MetricOur forecastGuidanceConsensus
    EPSno estimateno estimate-1,77
    Revenueno estimateno estimate54,0M USD
    Operating incomeno estimateno estimate-14,7M USD
    Full-year consensus mean (period as reported by source) · consensus in USD. Company-level full-year forecast and management guidance are not yet modelled at scale — shown as "no estimate", never inferred.
    Probabilistic model output — not investment advice. · generated 2026-08-04

    Options

    — missing data

    Short squeeze

    — missing data

    Earnings-call key lines

    — missing data

    Consensus distribution

    sell-side coverage
    Recommendation distribution3 analysts
    Strong buy0
    Buy3
    Hold0
    Sell0
    Strong sell0
    12-month price target$9,33 · Median $7,00
    Low $7,00High $14,00
    Operating income · consensus-14,7M USD
    EPS surprise
    −21,7 %
    reported vs consensus · miss
    Revenue surprise
    +22,9 %
    reported vs consensus · beat

    Estimate revisions

    consensus EPS · 26-week trend
    — missing data

    Sell-side observations

    Low$7,00
    Mean$9,33
    Median$7,00
    High$14,00
    Spot$2,25
    +314.8 %implied to mean12-month sell-side price targets · ▲ spot

    Themes

    — missing data

    ESG

    — missing data

    Risk factors

    Dilution riskLow
    Liquidity riskLow
    Filing-based flags
    • No immediate filing-based liquidity or dilution flags were detected.

    Benchmarks vs cohort

    Op Margin-11,4 %Below median
    Net Margin-20,6 %Below median
    ROE-9,4 %Below median
    D/E0,54Below median
    Cash Conv0,21Below median

    Corporate actions / M&A

    — missing data

    FX exposure

    — missing data

    Comparable transactions

    — missing data

    Derivatives & instruments

    — missing data

    Actions

    Ask Handelsavisen

    — missing data
    Data sources
    • Market data
    • Market data cache
    • Issuer disclosures
    • Public news
    • Earnings transcripts
    • Consensus estimates
    • ESG data
    How metrics are computed
    • Return On Equity
      net_income / total_equity
    • Price To Book
      market_price / (adjusted_book_value / shares_outstanding_diluted)
    • Dilution Ratio
      (shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
    • Market Price
      input from market-data provider (delayed close or quote-shim mid)
    • Market Cap
      market_price * shares_outstanding_diluted
    • Ev To Revenue
      enterprise_value / revenue
    Source documents
    • Aytu Biopharma Inc Market data — financials · 2026-05-27
    • Aytu Biopharma Inc Market data — analyst estimates · 2026-05-27
    • Aytu Biopharma Inc Market data — ESG · 2026-05-27

    Ownership & reference

    Top holders

    • Dimensional Fund Advisors, L.P.Investment Managers · as of 2026-03-310,00 %$0M
    • Geode Capital Management, L.L.C.Investment Managers · as of 2026-03-310,00 %$0M
    • Vanguard Capital Management, LLCInvestment Managers · as of 2025-12-310,00 %$1M
    • Northern Trust Investments, Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • BlackRock Institutional Trust Company, N.A.Investment Managers · as of 2024-06-300,00 %$0M
    • UBS Financial Services, Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • Wells Fargo AdvisorsBrokerage Firms · as of 2026-03-310,00 %$0M
    • Morgan Stanley Smith Barney LLCInvestment Managers · as of 2026-03-310,00 %$0M
    • JONES FINANCIAL COMPANIES LLLPInstitutional Investor · as of 2026-03-310,00 %$0M

    Insider activity

    Mixed / flat0 buys · 0 sellsnet $08 insiders · last 365d
    • DOCKERY CARLDirector · Common StockOther 10 000 · 2025-10-03
    • LIU VIVIAN HDirector · Common StockOther 10 000 · 2025-10-03
    • PYSZCZYMUKA GREGChief Commercial Officer · Common StockOther 12 500 · 2025-10-03
    • Disbrow JarrettChief Business Officer · Common StockOther 19 606 · 2025-10-03
    • Disbrow JarrettChief Business Officer · Common StockOther 12 500 · 2025-10-03
    • Disbrow Joshua R.Director, Chief Executive Officer · Common StockOther 31 446 · 2025-10-03
    • Selhorn Ryan JChief Financial Officer · Common StockOther 17 500 · 2025-10-03
    • Selhorn Ryan JChief Financial Officer · Common StockOther 16 243 · 2025-10-03
    • Disbrow Joshua R.Director, Chief Executive Officer · Common StockOther 22 500 · 2025-10-03
    • Donofrio John Jr.Director · Common StockOther 10 000 · 2025-10-03
    • JAIN ABHINAVDirector · Common StockOther 10 000 · 2025-10-03

    Short positioning

    347.0Kshares short-0.4% vs prior
    15.78days to cover
    41.8%short of daily vol
    2.1Kfails-to-deliver
    as of 2026-07-15 · short-interest report (free)

    Geographic breakdown

    — missing data
    Listings · one canonical issuer all listings resolve to the canonical
    AYTU.OCanonical
    NASDAQ · USD

    Intel & risk

    PredictorBeat prob45 %Surprise+0,00Full forecast →
    peak dispatch · —
    OSINT findings
    Dilution riskLow
    Liquidity riskLow
    No immediate filing-based liquidity or dilution flags were detected.

    Evidence & claims

    From filings & derived data
    • Total assets (YoY) (2025-12-31 vs 2024-12-31): 5.0%Derived (calculated)
    • Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): 47.2%Derived (calculated)
    • Long-term debt (YoY) (2025-12-31 vs 2024-12-31): 0.2%Derived (calculated)
    • Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): -53.8%Derived (calculated)
    • Current ratio (FY 2025-12-31): 1.16xDerived (calculated)
    • Current liabilities (annual): USD 65.56MSEC XBRL filing
    • Total assets (annual): USD 122MSEC XBRL filing
    • Cash & equivalents (annual): USD 30.02MSEC XBRL filing
    • Shareholders' equity (annual): USD 14.2MSEC XBRL filing
    • Current assets (annual): USD 76.24MSEC XBRL filing
    • Shares outstanding (annual): 10.73MSEC XBRL filing
    • Long-term debt (annual): USD 10MSEC XBRL filing
    • Cost of revenue (YoY) (2025-06-30 vs 2024-06-30): 27.4%Derived (calculated)
    • Capex (YoY) (2025-06-30 vs 2024-06-30): -30.7%Derived (calculated)
    • Net income (YoY) (2025-06-30 vs 2024-06-30): 14.4%Derived (calculated)
    • Operating cash flow (YoY) (2025-06-30 vs 2024-06-30): -39.6%Derived (calculated)
    • Gross margin (FY 2025-06-30): 69.0%Derived (calculated)
    • Gross profit (YoY) (2025-06-30 vs 2024-06-30): -6.6%Derived (calculated)
    • Net margin (FY 2025-06-30): -20.4%Derived (calculated)
    • EPS (basic) (YoY) (2025-06-30 vs 2024-06-30): 24.5%Derived (calculated)
    • Revenue (YoY) (2025-06-30 vs 2024-06-30): 1.8%Derived (calculated)
    • R&D expense (YoY) (2025-06-30 vs 2024-06-30): -52.1%Derived (calculated)
    • Operating income (YoY) (2025-06-30 vs 2024-06-30): -392.0%Derived (calculated)
    • Pre-tax income (annual): USD -13.74MSEC XBRL filing
    Showing 24 of 60 surfaced claims.
    Atomic claims from regulatory filings and derived calculations. Provenance shown as source kind only.

    The Thread

    Everything we know, in order
    2026-08-09EVENTUpcomingFY 2026 earnings (expected) estimated date
    2026-06-30 03:38 UTCEARNINGSUpcomingForecast: earnings_forecast (90d)
    2026-06-20 12:34 UTCANALYSTAnalyst coverage initiated
    2026-05-13FILINGFORM 10-Q →
    2026-05-13FILINGFORM 8-K →
    2026-04-02FILINGFORM 8-K →
    2026-02-03 16:10 UTCEARNINGSQuarterly results — Q4 2025 Revenue USD 15.2M · Net USD -10.6M
    2026-02-03FILINGFORM 10-Q →
    2026-02-03FILINGFORM 8-K →
    2026-01-20FILINGFORM 8-K →
    2025-12-10FILINGFORM 8-K →
    2025-11-13 16:12 UTCEARNINGSQuarterly results — Q3 2025 Revenue USD 13.9M · Net USD 2.0M
    2025-11-13FILINGFORM 10-Q →
    2025-11-13FILINGFORM 8-K →
    2025-10-24FILINGFORM DEF 14A →
    2025-10-03 00:00 UTCINSIDER11 insider transactions — 2025-10
    2025-10-03INSIDERDOCKERY CARL transacted 10.0k sh — Director
    2025-10-03INSIDERLIU VIVIAN H transacted 10.0k sh — Director
    2025-10-03INSIDERPYSZCZYMUKA GREG transacted 12.5k sh — Chief Commercial Officer
    2025-10-03INSIDERDisbrow Jarrett transacted 19.6k sh — Chief Business Officer
    2025-10-03INSIDERDisbrow Jarrett transacted 12.5k sh — Chief Business Officer
    2025-10-03INSIDERDisbrow Joshua R. transacted 31.4k sh — Director, Chief Executive Officer
    2025-10-03INSIDERSelhorn Ryan J transacted 17.5k sh — Chief Financial Officer
    2025-10-03INSIDERSelhorn Ryan J transacted 16.2k sh — Chief Financial Officer
    2025-10-03INSIDERDisbrow Joshua R. transacted 22.5k sh — Director, Chief Executive Officer
    2025-10-03INSIDERDonofrio John Jr. transacted 10.0k sh — Director
    2025-10-03INSIDERJAIN ABHINAV transacted 10.0k sh — Director
    2025-09-23 16:14 UTCEARNINGSQuarterly results — Q2 2025 Revenue USD 15.1M · Net USD -19.8M
    2025-09-23 16:14 UTCEARNINGSAnnual results — FY 2025 Revenue USD 66.4M · Net USD -13.6M
    2025-09-23FILINGFORM 10-K →
    2025-09-23FILINGFORM 8-K →
    2025-06-09 00:00 UTCINSIDER3 insider transactions — 2025-06 · net buy $125k 1 derivative
    2025-05-14 16:08 UTCEARNINGSQuarterly results — Q1 2025 Revenue USD 18.5M · Net USD 4.0M
    2025-03-31 00:00 UTCINSIDER2 insider transactions — 2025-03 1 derivative
    2025-02-28 00:00 UTCINSIDER3 insider transactions — 2025-02 1 derivative
    2025-02-12 16:14 UTCEARNINGSQuarterly results — Q4 2024 Revenue USD 16.2M · Net USD 0.8M
    2024-12-31 00:00 UTCINSIDER2 insider transactions — 2024-12 1 derivative
    2024-11-13 16:08 UTCEARNINGSQuarterly results — Q3 2024 Revenue USD 16.6M · Net USD 1.5M
    2024-11-11 00:00 UTCINSIDER8 insider transactions — 2024-11 3 derivative
    2024-09-26 16:46 UTCEARNINGSQuarterly results — Q2 2024 Revenue USD 14.6M · Net USD -4.6M
    Showing the 40 most recent of 47 entries.
    The entity's full life in the product — typed, chronological, joined across Newspaper, Platform and Data. Our memory, made visible.
    Sources filings · IR · transcripts · market data · tier hybrid · as of 2026-08-04 Market data · Issuer disclosures · Public news · Earnings transcripts · Consensus estimates · ESG data Premium coverage