Castle Biosciences Inc
Castle Biosciences is a molecular diagnostics company that generates revenue by providing test solutions for the diagnosis and treatment of dermatologic cancers, Barrett’s esophagus, atopic dermatitis, and uveal melanoma.
Business. Castle Biosciences is a molecular diagnostics company that generates revenue by providing test solutions for the diagnosis and treatment of dermatologic cancers, Barrett’s esophagus, atopic dermatitis, and uveal melanoma.
Analyst recommendations
9 analysts · consensus BuyAt a glance
What drives this business
The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
News & coverage
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- Company
- EarningsQ2 2026 earnings (confirmed · filed)2026-08-20
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
- Congressional trades
- CongressJosh Gottheimer — Castle Biosciences, Inc. - Common2022-03-15 · Democrat · NJ · Sale · $1,001 - $15,000
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
Castle Biosciences is a molecular diagnostics company that generates revenue by providing test solutions for the diagnosis and treatment of dermatologic cancers, Barrett’s esophagus, atopic dermatitis, and uveal melanoma.
Castle Biosciences maintains a conservative capital structure with a debt-to-equity ratio of 0.02 and a current ratio of 6.04, indicating strong short-term liquidity coverage. The balance sheet holds $62.1 million in cash and equivalents against $91.1 million in total liabilities, with long-term debt limited to $7.2 million. Despite this liquidity buffer, the company generated negative operating cash flow of $6.9 million and negative free cash flow of $28.0 million in Q2 2026, driven by $21.1 million in capital expenditures. The market capitalization stands at $844.1 million, implying a price-to-book ratio of 2.25 and an EV/Revenue multiple of 1.71.
Profitability remains negative as the company invests in growth, reporting a net loss of $16.6 million and an operating loss of $21.5 million for the quarter. Return on equity is -5.14% and return on assets is -4.3%, reflecting the early-stage commercial or expansion phase typical of specialized diagnostics firms. The company carries an accumulated deficit of $240.9 million, offset by $711.1 million in additional paid-in capital. Stock-based compensation expense of $21.4 million in the first half of 2026 highlights the reliance on equity incentives to retain talent in a competitive sector.
- Strong liquidity position with a 6.04 current ratio and $62.1 million in cash, but significant cash burn of $54.6 million in H1 2026.
- Negative profitability with a $16.6 million net loss in Q2 2026, driven by high operating expenses and stock-based compensation.
- Medium dilution risk flagged due to potential strategic transactions and equity-based compensation practices.
- Positive analyst sentiment with a mean price target of $43.56, implying substantial upside from the current $28.00 market price.
- Revenue scale of $187.2 million in Q2 2026 supports a 1.71 EV/Revenue multiple, reflecting investor confidence in future growth.
- Capital expenditures of $21.1 million in Q2 2026 indicate ongoing investment in infrastructure and diagnostic capabilities.
Bull / Bear case
Generated · model-assistedIn focus — financials by report
Revenue $187.2M; Operating income -$21.5M.
- ▍Revenue $187.2M
- ▍Operating income -$21.5M
- ▍Net margin -8.9%
Revenue $83.7M; Operating income -$18.4M.
- ▍Revenue $83.7M
- ▍Operating income -$18.4M
- ▍Net margin -17.4%
Revenue $344.2M; Operating income -$42.8M.
- ▍Revenue $344.2M
- ▍Operating income -$42.8M
- ▍Net margin -7.0%
Revenue $332.1M; Operating income $8.7M.
- ▍Revenue $332.1M
- ▍Operating income $8.7M
- ▍Net margin 5.5%
Revenue $332.1M; Operating income $8.7M.
- ▍Revenue $332.1M
- ▍Operating income $8.7M
- ▍Net margin 5.5%
Revenue $219.8M; Operating income -$68.0M.
- ▍Revenue $219.8M
- ▍Operating income -$68.0M
- ▍Net margin -26.1%
Revenue $219.8M; Operating income -$68.0M.
- ▍Revenue $219.8M
- ▍Operating income -$68.0M
- ▍Net margin -26.1%
Valuation FY
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -1,46 |
| Revenue | —no estimate | —no estimate | 363,8M USD |
| Operating income | —no estimate | —no estimate | -47,8M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- Source documents mention dilution or offering risk.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Director, Pres. & Chief Exec. Officer · Stock option (right to buy) → Common StockDisposed 6 214 @ $2,39exercise · 2026-07-27
- Director, Pres. & Chief Exec. Officer · Stock option (right to buy) → Common StockDisposed 550 @ $2,39exercise · 2026-07-14
- Director, Pres. & Chief Exec. Officer · Stock option (right to buy) → Common StockDisposed 6 214 @ $2,39exercise · 2026-07-01
- Director, Pres. & Chief Exec. Officer · Stock option (right to buy) → Common StockDisposed 550 @ $2,39exercise · 2026-06-15
- Director, Pres. & Chief Exec. Officer · Stock option (right to buy) → Common StockDisposed 204 @ $2,39exercise · 2026-06-01
- Director, Pres. & Chief Exec. Officer · Stock option (right to buy) → Common StockDisposed 6 010 @ $2,39exercise · 2026-06-01
- Director · Restricted Stock Units → Common StockAcquired 11 766grant · 2026-05-28
- Director · Restricted Stock Units → Common StockAcquired 11 766grant · 2026-05-28
- Director · Restricted Stock Units → Common StockAcquired 11 766grant · 2026-05-28
- Director · Restricted Stock Units → Common StockAcquired 11 766grant · 2026-05-28
- Director · Restricted Stock Units → Common StockAcquired 11 766grant · 2026-05-28
- Director · Restricted Stock Units → Common StockAcquired 11 766grant · 2026-05-28
- Director · Restricted Stock Units → Common StockAcquired 11 766grant · 2026-05-28
- Director · Restricted Stock Units → Common StockDisposed 13 667exercise · 2026-05-22
- Director · Restricted Stock Units → Common StockDisposed 13 667exercise · 2026-05-22
- Director · Restricted Stock Units → Common StockDisposed 13 667exercise · 2026-05-22
- Director · Restricted Stock Units → Common StockDisposed 13 667exercise · 2026-05-22
- Director · Restricted Stock Units → Common StockDisposed 13 667exercise · 2026-05-22
- Director · Restricted Stock Units → Common StockDisposed 13 667exercise · 2026-05-22
- Director · Restricted Stock Units → Common StockDisposed 13 667exercise · 2026-05-22
- Director, Pres. & Chief Exec. Officer · Stock option (right to buy) → Common StockDisposed 420 @ $2,39exercise · 2026-05-21
- Chief Commercial Officer · Stock option (right to buy) → Common StockDisposed 11 210 @ $3,38exercise · 2026-05-21
- Director, Pres. & Chief Exec. Officer · Stock option (right to buy) → Common StockDisposed 130 @ $2,39exercise · 2026-05-20
- Director, Pres. & Chief Exec. Officer · Stock option (right to buy) → Common StockDisposed 6 214 @ $2,39exercise · 2026-05-07
- Director, Pres. & Chief Exec. Officer · Stock option (right to buy) → Common StockDisposed 550 @ $2,39exercise · 2026-04-21
Actions
Ask Handelsavisen
- Market data
- Regulatory filings
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Reference data
- Cash Conversion Ratiooperating_cash_flow / net_income
- Market Priceinput from market-data provider (delayed close or quote-shim mid)
- Ev To Revenueenterprise_value / revenue
- Net Cashcash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
- Return On Equitynet_income / total_equity
- Market Capmarket_price * shares_outstanding_diluted
- CASTLE BIOSCIENCES INC company facts · 2026-08-01
- CASTLE BIOSCIENCES INC 10-Q 2026-07-30 · 2026-08-01
- CASTLE BIOSCIENCES INC 10-Q 2026-05-06 · 2026-08-01
- CASTLE BIOSCIENCES INC 10-K 2026-02-26 · 2026-08-01
- CASTLE BIOSCIENCES INC 10-Q 2025-11-03 · 2026-08-01
- 8-K (sec_8k_material) on CSTL · 2026-08-01
- Castle Biosciences Inc Market data — analyst estimates · 2026-08-01
- Castle Biosciences Inc Market data — ESG · 2026-08-01
- CASTLE BIOSCIENCES INC HA canonical relationships · 2026-08-01
Ownership & reference
Top holders
- Investment Managers · as of 2026-03-310,02 %$43M
- Investment Managers · as of 2026-03-310,01 %$26M
- Investment Managers · as of 2024-12-310,00 %$12M
- Investment Managers · as of 2024-06-300,00 %$66M
- Investment Managers · as of 2025-12-310,00 %$86M
- Investment Managers · as of 2026-03-310,00 %$18M
- Investment Managers · as of 2026-03-310,00 %$8M
- Investment Managers · as of 2026-03-310,00 %$2M
- Investment Managers · as of 2026-03-310,00 %$6M
- Investment Managers · as of 2026-03-310,00 %$7M
- Investment Managers · as of 2026-03-310,00 %$2M
- Investment Managers · as of 2026-03-310,00 %$19M
- Investment Managers · as of 2026-03-310,00 %$11M
- Investment Managers · as of 2026-03-310,00 %$2M
- Institutional Investor · as of 2026-03-310,00 %$2M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$1M
- Funds · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$1M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$0M
- Brokerage Firms · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
Insider activity
- Director, Pres. & Chief Exec. Officer · Common StockSold 1 110 @ $24,13$27K · 2026-07-27
- Director, Pres. & Chief Exec. Officer · Common StockSold 10 @ $25,06$251 · 2026-07-27
- Director, Pres. & Chief Exec. Officer · Common StockSold 43 @ $25,06$1K · 2026-07-27
- Director, Pres. & Chief Exec. Officer · Common StockSold 50 @ $25,06$1K · 2026-07-27
- Director, Pres. & Chief Exec. Officer · Common StockSold 232 @ $25,06$6K · 2026-07-27
- Director, Pres. & Chief Exec. Officer · Common StockSold 268 @ $24,13$6K · 2026-07-27
- Director, Pres. & Chief Exec. Officer · Common StockSold 1 307 @ $24,13$32K · 2026-07-27
- Director, Pres. & Chief Exec. Officer · Common StockSold 5 982 @ $24,13$144K · 2026-07-27
- Director, Pres. & Chief Exec. Officer · Common StockOther 6 214 @ $2,39$15K · 2026-07-27
- Director, Pres. & Chief Exec. Officer · Common StockSold 550 @ $22,92$13K · 2026-07-14
- Director, Pres. & Chief Exec. Officer · Common StockSold 278 @ $22,92$6K · 2026-07-14
- Director, Pres. & Chief Exec. Officer · Common StockSold 1 153 @ $22,92$26K · 2026-07-14
- Director, Pres. & Chief Exec. Officer · Common StockOther 550 @ $2,39$1K · 2026-07-14
- Director, Pres. & Chief Exec. Officer · Common StockSold 1 357 @ $22,92$31K · 2026-07-14
- Chief Operating Officer · Common StockSold 8 186 @ $24,40$200K · 2026-07-01
- Director, Pres. & Chief Exec. Officer · Common StockOther 6 214 @ $2,39$15K · 2026-07-01
- Chief Operating Officer · Common StockSold 400 @ $24,78$10K · 2026-07-01
- Director, Pres. & Chief Exec. Officer · Common StockSold 6 214 @ $24,29$151K · 2026-07-01
- Director, Pres. & Chief Exec. Officer · Common StockSold 1 357 @ $24,29$33K · 2026-07-01
- Director, Pres. & Chief Exec. Officer · Common StockSold 1 153 @ $24,29$28K · 2026-07-01
- Director, Pres. & Chief Exec. Officer · Common StockSold 278 @ $24,29$7K · 2026-07-01
- Chief Operating Officer · Common StockSold 8 587 @ $20,71$178K · 2026-06-16
- Director, Pres. & Chief Exec. Officer · Common StockOther 550 @ $2,39$1K · 2026-06-15
- Director, Pres. & Chief Exec. Officer · Common StockSold 550 @ $20,66$11K · 2026-06-15
- Director, Pres. & Chief Exec. Officer · Common StockSold 1 357 @ $20,66$28K · 2026-06-15
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Operating income (annual): USD -42.81MUnknown
- Total liabilities (annual): USD 107.68MUnknown
- Operating cash flow (annual): USD 64.35MUnknown
- R&D expense (annual): USD 51.85MUnknown
- Current assets (annual): USD 361.1MUnknown
- Long-term debt (annual): USD 10.06MUnknown
- Shareholders' equity (annual): USD 470.87MUnknown
- Current liabilities (annual): USD 68.68MUnknown
- Shares outstanding (annual): 29.69MUnknown
- Net income (annual): USD -24.16MUnknown
- Cost of revenue (annual): USD 71.03MUnknown
- EPS (basic) (annual): USD-PER-SHARES -1Unknown
- Cash & equivalents (annual): USD 116.73MUnknown
- EPS (diluted) (annual): USD-PER-SHARES -1Unknown
- Revenue (annual): USD 344.23MUnknown
- Capex (annual): USD 36.02MUnknown
- Total assets (annual): USD 578.56MUnknown
- Operating income (annual): USD 8.67MUnknown
- Shareholders' equity (annual): USD 455.83MUnknown
- Shares outstanding (annual): 28.48MUnknown
- Total assets (annual): USD 531.24MUnknown
- Current assets (annual): USD 360.15MUnknown
- R&D expense (annual): USD 52.04MUnknown
- Total liabilities (annual): USD 75.4MUnknown