Dianthus Therapeutics Inc
Dianthus Therapeutics Inc is a biotechnology company operating in the Health Care sector, currently generating minimal revenue while incurring significant operating losses consistent with early-stage clinical development.
Business. Dianthus Therapeutics Inc (DNTH.O) is a biotechnology company operating within the Health Care sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.
At a glance
What drives this business
The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
News & coverage
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Analysis
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- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Dianthus Therapeutics Inc (DNTH.O) has recorded a major holder change involving investor ID 587, with conflicting data points detected in late June 2026. One signal, detected on June 24, 2026, indicates a reduction in holdings from 37,228 shares to 132 shares as of March 31, 2026. Conversely, a separate signal detected on June 21, 2026, suggests an increase from 132 shares to 37,228 shares for the same period. Both changes are classified as major severity, highlighting significant volatility or data correction activity regarding this specific investor's position. This activity is particularly notable given the company's current market profile. Dianthus Therapeutics is a micro-cap entity with no analyst coverage and no index membership, relying on a base of 32 top holders for its shareholder structure. The company also reports only one officer, suggesting a lean operational team. In the absence of broader market commentary or analyst ratings, movements by individual holders carry disproportionate weight in signaling investor sentiment. The conflicting nature of the holder change signals—showing both a drastic sell-off and a substantial buy-in for the same investor ID within a three-day detection window—underscores the need for caution in interpreting these data points. The value associated with the larger position is approximately $3.12 million, representing a weight of roughly 0.0018% of the total, while the smaller position is valued at roughly $11,077. The discrepancy may reflect data corrections or complex trading activities that have not yet been reconciled in public filings. As this is the first analysis for this ticker, there is no prior basis for computing deltas in material changes. Consequently, the significance of this holder activity must be viewed in isolation, without historical context from previous reporting periods. Investors should monitor subsequent filings to determine the final, accurate position of investor ID 587, as the current signals present contradictory narratives regarding capital flow into or out of Dianthus Therapeutics.
Signals & dispatch
Composite-score breakdown
Synthesis
Dianthus Therapeutics Inc (DNTH.O) is a biotechnology company operating within the Health Care sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.
Dianthus Therapeutics maintains a conservative capital structure with zero debt, resulting in a debt-to-equity ratio of 0.0. The balance sheet shows total assets of $530.9 million against total liabilities of $37.5 million, leaving total equity at $493.4 million. Cash and equivalents stand at $51.1 million, which serves as the primary liquidity buffer. However, the company faces a negative operating cash flow of $129.1 million, indicating a substantial cash burn rate that exceeds current liquid reserves on an annualized basis. The risk assessment flags liquidity as low, reflecting the tension between the cash balance and the high operational expenditure required to sustain the business.
Profitability metrics are deeply negative, reflecting the pre-commercial stage of the business. Return on equity is -0.329 and return on assets is -0.3058, indicating that the company is destroying capital value in the current period. Net income stands at a loss of $162.3 million against revenue of only $2.0 million. This extreme disparity between revenue and net loss is typical for biotechnology firms in the research and development phase, where expenses are dominated by clinical trials and R&D rather than product sales. Without cohort median data for direct comparison, these figures are evaluated against industry norms for early-stage biotechs, where negative returns are expected but the magnitude of the loss relative to cash reserves is a critical monitoring point.
Dianthus Therapeutics Inc (DNTH.O) has recorded a major holder change involving investor ID 587, with conflicting data points detected in late June 2026. One signal, detected on June 24, 2026, indicates a reduction in holdings from 37,228 shares to 132 shares as of March 31, 2026. Conversely, a separate signal detected on June 21, 2026, suggests an increase from 132 shares to 37,228 shares for the same period. Both changes are classified as major severity, highlighting significant volatility or data correction activity regarding this specific investor's position. This activity is particularly notable given the company's current market profile. Dianthus Therapeutics is a micro-cap entity with no analyst coverage and no index membership, relying on a base of 32 top holders for its shareholder structure. The company also reports only one officer, suggesting a lean operational team. In the absence of broader market commentary or analyst ratings, movements by individual holders carry disproportionate weight in signaling investor sentiment. The conflicting nature of the holder change signals—showing both a drastic sell-off and a substantial buy-in for the same investor ID within a three-day detection window—underscores the need for caution in interpreting these data points. The value associated with the larger position is approximately $3.12 million, representing a weight of roughly 0.0018% of the total, while the smaller position is valued at roughly $11,077. The discrepancy may reflect data corrections or complex trading activities that have not yet been reconciled in public filings. As this is the first analysis for this ticker, there is no prior basis for computing deltas in material changes. Consequently, the significance of this holder activity must be viewed in isolation, without historical context from previous reporting periods. Investors should monitor subsequent filings to determine the final, accurate position of investor ID 587, as the current signals present contradictory narratives regarding capital flow into or out of Dianthus Therapeutics.
- Dianthus Therapeutics has a debt-free balance sheet with $51.1 million in cash, but this is insufficient to cover the $129.1 million annual operating cash outflow.
- The company is deeply unprofitable with a net loss of $162.3 million and negligible revenue of $2.0 million, consistent with early-stage biotech R&D phases.
- Liquidity risk is rated as low, signaling a potential mismatch between current cash reserves and the runway required to sustain operations without new capital.
- Dilution risk is currently assessed as low, but the high cash burn rate implies a high likelihood of future equity issuance to fund operations.
- No recent news or filing events are recorded, suggesting a quiet period in public disclosures or clinical updates.
Bull / Bear case
Generated · model-assistedIn focus — financials by report
Valuation
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -3,74 |
| Revenue | —no estimate | —no estimate | 1,2M USD |
| Operating income | —no estimate | —no estimate | -219,6M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- EVP, CFO & CBO · Stock Option (Right to Buy) → Common StockDisposed 31 249 @ $21,77exercise · 2026-07-09
- SVP, General Counsel and Sec. · Stock Option (Right to Buy) → Common StockDisposed 30 000 @ $17,88exercise · 2026-06-17
- EVP, Head of R&D · Stock Option (Right to Buy) → Common StockDisposed 6 908 @ $17,88exercise · 2026-06-01
- EVP, Head of R&D · Stock Option (Right to Buy) → Common StockDisposed 3 998 @ $8,44exercise · 2026-06-01
- EVP, Head of R&D · Stock Option (Right to Buy) → Common StockDisposed 6 249 @ $21,77exercise · 2026-06-01
- EVP, Head of R&D · Stock Option (Right to Buy) → Common StockDisposed 9 375 @ $22,07exercise · 2026-06-01
- Director · Stock Option (Right to Buy) → Common StockAcquired 6 090 @ $89,63grant · 2026-05-21
- Director · Stock Option (Right to Buy) → Common StockAcquired 6 090 @ $89,63grant · 2026-05-21
- Director · Stock Option (Right to Buy) → Common StockAcquired 6 090 @ $89,63grant · 2026-05-21
- Director · Stock Option (Right to Buy) → Common StockAcquired 6 090 @ $89,63grant · 2026-05-21
- Director · Stock Option (Right to Buy) → Common StockAcquired 6 090 @ $89,63grant · 2026-05-21
- Director · Stock Option (Right to Buy) → Common StockAcquired 6 090 @ $89,63grant · 2026-05-21
- Director · Stock Option (Right to Buy) → Common StockAcquired 6 090 @ $89,63grant · 2026-05-21
- Director · Stock Option (Right to Buy) → Common StockDisposed 599 @ $8,44exercise · 2026-05-08
- EVP, CFO & CBO · Stock Option (Right to Buy) → Common StockDisposed 8 224 @ $17,88exercise · 2026-04-09
- Director · Stock Option (Right to Buy) → Common StockDisposed 599 @ $8,44exercise · 2026-03-31
- EVP, CFO & CBO · Stock Option (Right to Buy) → Common StockDisposed 74 367 @ $8,44exercise · 2026-03-31
- EVP, CFO & CBO · Stock Option (Right to Buy) → Common StockDisposed 40 000 @ $17,88exercise · 2026-03-31
- Director · Stock Option (Right to Buy) → Common StockDisposed 27 594 @ $8,44exercise · 2026-03-24
- Director, CEO AND PRESIDENT · Stock Option (Right to Buy) → Common StockDisposed 59 700 @ $6,70exercise · 2026-03-16
- Director, CEO AND PRESIDENT · Stock Option (Right to Buy) → Common StockDisposed 5 592 @ $17,88exercise · 2026-03-16
- CHIEF ACCOUNTING OFFICER · Stock Option (Right to Buy) → Common StockDisposed 16 182 @ $17,88exercise · 2026-03-12
- Director, CEO AND PRESIDENT · Stock Option (Right to Buy) → Common StockDisposed 122 918 @ $6,70exercise · 2026-03-12
- CHIEF ACCOUNTING OFFICER · Stock Option (Right to Buy) → Common StockDisposed 10 000 @ $21,77exercise · 2026-03-12
- CHIEF ACCOUNTING OFFICER · Stock Option (Right to Buy) → Common StockDisposed 17 500 @ $22,07exercise · 2026-03-12
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Reference data
- Return On Equitynet_income / total_equity
- Cash Conversion Ratiooperating_cash_flow / net_income
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Return On Assetsnet_income / total_assets
- Net Cashcash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
- Debt To Equity(short_term_debt + long_term_debt) / total_equity
- Dianthus Therapeutics, Inc. Market data — financials · 2026-07-28
- reconciler_enqueue (reconciler) on DNTH.O · 2026-07-28
Ownership & reference
Top holders
- Investment Managers · as of 2026-03-310,07 %$0M
- Investment Managers · as of 2026-03-310,04 %$218M
- Institutional Investor · as of 2026-03-310,03 %$652M
- Investment Managers · as of 2026-03-310,03 %$41M
- Investment Managers · as of 2026-03-310,02 %$81M
- Investment Managers · as of 2026-03-310,01 %$38M
- Investment Managers · as of 2026-03-310,01 %$66M
- Investment Managers · as of 2026-03-310,01 %$0M
- Institutional Investor · as of 2026-03-310,01 %$30M
- Investment Managers · as of 2026-03-310,01 %$46M
- Investment Managers · as of 2026-03-310,01 %$27M
- Investment Managers · as of 2026-03-310,00 %$77M
- Investment Managers · as of 2026-03-310,00 %$117M
- Investment Managers · as of 2026-03-310,00 %$26M
- Investment Managers · as of 2026-03-310,00 %$7M
- Investment Managers · as of 2026-03-310,00 %$25M
- Institutional Investor · as of 2026-03-310,00 %$16M
- Investment Managers · as of 2026-03-310,00 %$3M
- Funds · as of 2026-03-310,00 %$11M
- Investment Managers · as of 2025-12-310,00 %$84M
- Investment Managers · as of 2024-06-300,00 %$41M
- Investment Managers · as of 2026-03-310,00 %$3M
- Investment Managers · as of 2026-03-310,00 %$1M
- Institutional Investor · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$8M
- Investment Managers · as of 2024-12-310,00 %$1M
- Brokerage Firms · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$1M
- Brokerage Firms · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
Leadership
- Marino GarciaPresident, Chief Executive Officer, Director
Insider activity
- EVP, CFO & CBO · Common StockSold 15 329 @ $101,24$1,6M · 2026-07-09
- EVP, CFO & CBO · Common StockSold 10 354 @ $100,22$1,0M · 2026-07-09
- EVP, CFO & CBO · Common StockOther 31 249 @ $21,77$680K · 2026-07-09
- EVP, CFO & CBO · Common StockSold 5 566 @ $101,97$568K · 2026-07-09
- SVP, General Counsel and Sec. · Common StockOther 30 000 @ $17,88$536K · 2026-06-17
- SVP, General Counsel and Sec. · Common StockSold 16 771 @ $80,34$1,3M · 2026-06-17
- SVP, General Counsel and Sec. · Common StockSold 13 229 @ $81,38$1,1M · 2026-06-17
- EVP, Head of R&D · Common StockOther 3 998 @ $8,44$34K · 2026-06-01
- EVP, Head of R&D · Common StockOther 6 908 @ $17,88$124K · 2026-06-01
- EVP, Head of R&D · Common StockOther 6 249 @ $21,77$136K · 2026-06-01
- EVP, Head of R&D · Common StockOther 9 375 @ $22,07$207K · 2026-06-01
- EVP, Head of R&D · Common StockSold 5 428 @ $89,72$487K · 2026-06-01
- EVP, Head of R&D · Common StockSold 16 943 @ $90,72$1,5M · 2026-06-01
- EVP, Head of R&D · Common StockSold 4 159 @ $91,37$380K · 2026-06-01
- Director · Common StockOther 599 @ $8,44$5K · 2026-05-08
- Director · Common StockSold 599 @ $85,47$51K · 2026-05-08
- EVP, CFO & CBO · Common StockOther 8 224 @ $17,88$147K · 2026-04-09
- EVP, CFO & CBO · Common StockSold 8 224 @ $89,84$739K · 2026-04-09
- Director · Common StockOther 599 @ $8,44$5K · 2026-03-31
- EVP, CFO & CBO · Common StockOther 74 367 @ $8,44$628K · 2026-03-31
- EVP, CFO & CBO · Common StockOther 40 000 @ $17,88$715K · 2026-03-31
- EVP, CFO & CBO · Common StockSold 1 390 @ $78,33$109K · 2026-03-31
- EVP, CFO & CBO · Common StockSold 21 825 @ $78,86$1,7M · 2026-03-31
- EVP, CFO & CBO · Common StockSold 1 485 @ $80,25$119K · 2026-03-31
- EVP, CFO & CBO · Common StockSold 800 @ $81,36$65K · 2026-03-31
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Cash & equivalents (annual): USD 51.09MUnknown
- Operating cash flow (annual): USD -129.06MUnknown
- Operating income (annual): USD -177.93MUnknown
- Revenue (annual): USD 2.04MUnknown
- Net income (annual): USD -162.34MUnknown
- Shareholders' equity (annual): USD 493.4MUnknown
- Current assets (annual): USD 409.44MUnknown
- Total operating expenses (annual): USD 179.97MUnknown
- Total liabilities (annual): USD 37.52MUnknown
- EPS (basic) (annual): USD-PER-SHARES -4Unknown
- Total assets (annual): USD 530.92MUnknown
- Current liabilities (annual): USD 30.73MUnknown
- R&D expense (annual): USD 145.64MUnknown
- EPS (diluted) (annual): USD-PER-SHARES -4Unknown
- Shares outstanding (annual): 43.22MUnknown
- R&D expense (annual): USD 83.11MUnknown
- Net income (annual): USD -84.97MUnknown
- Shares outstanding (annual): 31.12MUnknown
- Current liabilities (annual): USD 18.45MUnknown
- Total liabilities (annual): USD 21.53MUnknown
- EPS (basic) (annual): USD-PER-SHARES -3Unknown
- Current assets (annual): USD 280.9MUnknown
- Total assets (annual): USD 374.01MUnknown
- EPS (diluted) (annual): USD-PER-SHARES -3Unknown