Fulc.O
Fulcrum Therapeutics Inc operates in the Health Care sector, specifically within the Pharmaceuticals industry, though its specific business activity and revenue-generating mechanisms are currently unclassified in the available data.
Business. Fulcrum Therapeutics Inc operates in the Health Care sector, specifically within the Pharmaceuticals industry, though its specific business activity and revenue-generating mechanisms are currently unclassified in the available data.
At a glance
What drives this business
The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
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- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
Fulcrum Therapeutics Inc operates in the Health Care sector, specifically within the Pharmaceuticals industry, though its specific business activity and revenue-generating mechanisms are currently unclassified in the available data.
(a) Capital structure and liquidity: The company maintains a conservative balance sheet with total assets of $366.3 million and total liabilities of $17.3 million, resulting in a debt-to-equity ratio of 0.0. Total equity stands at $349.0 million, supported by cash and equivalents of $197.5 million. Despite the strong cash position, operating cash flow is negative at -$60.1 million, indicating ongoing cash burn from operations. Capital expenditure is minimal at $0.3 million, suggesting limited investment in physical assets.
(b) Profitability and returns: The company is not yet profitable, reporting zero revenue and an operating income of -$84.8 million. Net income is -$74.9 million, leading to a return on equity of -21.46% and a return on assets of -20.44%. These negative returns reflect the pre-revenue stage of the business, where costs are incurred without corresponding sales.
(c) Segments and geographic exposure: No segment or geographic revenue data is available, as the company reports zero revenue. The classification as a pharmaceutical company suggests potential future exposure to global healthcare markets, but current concentration risks cannot be assessed due to the absence of sales data.
(d) Growth trajectory: With zero revenue reported, there is no historical growth trajectory to analyze. The company appears to be in a development phase, focusing on research and development rather than commercial sales. The negative operating income and cash flow suggest that the company is investing heavily in its pipeline, but the lack of revenue prevents any assessment of growth trends.
(e) Risk factors: The risk assessment indicates low liquidity risk and low dilution risk, with no immediate filing-based flags detected. However, the negative cash flow and lack of revenue pose inherent risks to the company's ability to sustain operations without additional capital. The low classification confidence also suggests uncertainty in the company's strategic direction or market positioning.
(f) Recent events: Recent news observations indicate reconciler enqueue events for Fulcrum Therapeutics Inc, related to coverage closure and analysis job processing. These events are administrative in nature and do not provide insight into the company's operational or financial performance.
- Fulcrum Therapeutics Inc is a pre-revenue pharmaceutical company with a strong cash position of $197.5 million but negative operating cash flow of -$60.1 million.
- The company has zero debt, resulting in a debt-to-equity ratio of 0.0, which provides financial flexibility but also indicates a lack of leverage for growth.
- Negative returns on equity (-21.46%) and assets (-20.44%) reflect the pre-commercial stage of the business, with no revenue to offset operating costs.
- Low liquidity and dilution risks are noted, but the absence of revenue and negative cash flow pose long-term sustainability challenges.
- Recent administrative events do not provide material insights into the company's operational or financial health.
Bull / Bear case
analysis pipelineIn focus — financials by report
Valuation
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Director · Stock Option (right to buy) → Common StockAcquired 32 000 @ $3,66grant · 2026-06-30
- Director · Stock Option (right to buy) → Common StockAcquired 32 000 @ $3,66grant · 2026-06-30
- Director · Stock Option (right to buy) → Common StockAcquired 32 000 @ $3,66grant · 2026-06-30
- Director · Stock Option (right to buy) → Common StockAcquired 32 000 @ $3,66grant · 2026-06-30
- Director · Stock Option (right to buy) → Common StockAcquired 32 000 @ $3,66grant · 2026-06-30
- Director · Stock Option (right to buy) → Common StockAcquired 32 000 @ $3,66grant · 2026-06-30
- Director · Stock Option (right to buy) → Common StockAcquired 32 000 @ $3,66grant · 2026-06-30
- Director · Stock Option (right to buy) → Common StockAcquired 32 000 @ $3,66grant · 2026-06-30
- Director · Stock Option (right to buy) → Common StockAcquired 64 000 @ $8,08grant · 2026-04-23
- Chief Legal Officer · Stock Option (right to buy) → Common StockAcquired 170 000 @ $10,72grant · 2026-02-02
- Chief Financial Officer · Stock Option (right to buy) → Common StockAcquired 170 000 @ $10,72grant · 2026-02-02
- Principal Accounting Officer · Stock Option (right to buy) → Common StockAcquired 57 000 @ $10,72grant · 2026-02-02
- Director, See Remarks · Stock option - Right to Buy → Common StockAcquired 650 000 @ $10,72grant · 2026-02-02
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Reference data
- Cash Conversion Ratiooperating_cash_flow / net_income
- Debt To Equity(short_term_debt + long_term_debt) / total_equity
- Return On Equitynet_income / total_equity
- Net Cashcash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Return On Assetsnet_income / total_assets
- FULCRUM THERAPEUTICS, INC. Market data — financials · 2026-07-29
- reconciler_enqueue (reconciler) on FULC.O · 2026-07-29
Ownership & reference
Top holders
- Investment Managers · as of 2026-03-310,00 %$4M
- Investment Managers · as of 2026-03-310,00 %$9M
- Investment Managers · as of 2026-03-310,00 %$11M
- Investment Managers · as of 2024-06-300,00 %$30M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2025-12-310,00 %$40M
- Investment Managers · as of 2026-03-310,00 %$4M
- Investment Managers · as of 2026-03-310,00 %$3M
- Investment Managers · as of 2026-03-310,00 %$4M
- Investment Managers · as of 2026-03-310,00 %$2M
- Investment Managers · as of 2026-03-310,00 %$12M
- Investment Managers · as of 2024-12-310,00 %$1M
- Institutional Investor · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$1M
- Funds · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$0M
- Brokerage Firms · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
Leadership
- Alex C. SapirPresident, Chief Executive Officer, Director
Insider activity
- 10% owner · Common StockBought 50 945 @ $3,52$179K · 2026-07-17
- 10% owner · Common StockBought 116 671 @ $3,56$415K · 2026-07-16
- 10% owner · Common StockBought 107 377 @ $3,56$382K · 2026-07-15
- 10% owner · Common StockBought 53 651 @ $3,56$191K · 2026-07-14
- 10% owner · Common StockBought 75 952 @ $3,58$272K · 2026-07-14
- 10% owner · Common StockBought 12 966 @ $3,54$46K · 2026-07-13
- Director · Common StockSold 18 000 @ $3,65$66K · 2026-06-26
- Director · Common StockSold 15 000 @ $10,72$161K · 2026-02-02
- Director · Common StockSold 15 000 @ $11,87$178K · 2026-01-02
- Chief Legal Officer · Common StockSold 3 452 @ $12,92$45K · 2025-12-15
- 10% owner · Common StockSold 1 377 020 @ $13,33$18,4M · 2025-12-08
- 10% owner · Common StockSold 2 706 397 @ $14,28$38,6M · 2025-12-08
- 10% owner · Common StockSold 91 722 @ $14,98$1,4M · 2025-12-08
- Director · Common StockSold 15 000 @ $11,03$165K · 2025-11-19
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Operating income (annual): USD -84.77MUnknown
- Net income (annual): USD -74.88MUnknown
- EPS (diluted) (annual): USD-PER-SHARES -1Unknown
- Total operating expenses (annual): USD 84.77MUnknown
- Current liabilities (annual): USD 13.05MUnknown
- R&D expense (annual): USD 56.1MUnknown
- Operating cash flow (annual): USD -60.06MUnknown
- Total liabilities (annual): USD 17.28MUnknown
- Capex (annual): USD 314KUnknown
- Current assets (annual): USD 357.48MUnknown
- EPS (basic) (annual): USD-PER-SHARES -1Unknown
- Total assets (annual): USD 366.28MUnknown
- Cash & equivalents (annual): USD 197.53MUnknown
- Shares outstanding (annual): 66.58MUnknown
- Shareholders' equity (annual): USD 349MUnknown
- Total liabilities (annual): USD 17.68MUnknown
- Total operating expenses (annual): USD 101.9MUnknown
- Operating income (annual): USD -21.9MUnknown
- Capex (annual): USD 278KUnknown
- EPS (diluted) (annual): USD-PER-SHARES -0Unknown
- Operating cash flow (annual): USD -2.22MUnknown
- Cash & equivalents (annual): USD 58.21MUnknown
- EPS (basic) (annual): USD-PER-SHARES -0Unknown
- Current assets (annual): USD 249.92MUnknown