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GUTS.O NASDAQ Biotechnology & Medical Research

Fractyl Health Inc

$0,78
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Mcap
123,0M USD
P/E
EV / Rev
Div yield
Op margin
-65 278,8 %
ROE
-4,0 %
Net margin
-10 066,7 %
Debt / equity
0,34
Beta
52w range
Volume
6
Day range
Prev close
$0,86
Open
$0,92
Next earnings
2026-10-28
Ex-dividend
TR 1Y
About

Fractyl Health Inc is a biotechnology company focused on developing and commercializing medical devices for the treatment of type 2 diabetes and related metabolic conditions.

Business. Fractyl Health Inc (GUTS.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.

Classification92 %
SectorHealthcare
Business sectorPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
ActivityPharmaceuticals & Medical Research
Generated · model-assisted
Sell-side consensus
BUY5 analysts
4 buy1 hold0 sell
Avg 12m price target5,24

Analyst recommendations

5 analysts · consensus Buy
Buy4
Hold1
Sell0
12-month price target
5,24
Consensus of sell-side coverage.
Upcoming events
  • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
See all catalysts →

At a glance

Score
not yet scored
Valuation
valuation pending
Analysts
Buy
5 analysts · indicative
Ownership
Vanguard Capital Management, LLC
largest disclosed fund holder
Profitability
-4,0 %
return on equity
Quality
not yet scored

What drives this business

The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.

— missing data

News & coverage

0
  • No recent newsroom coverage mentioning GUTS.
  • Sector rotation

    Sector1D1Mvs mkt
    Materials+2,3 %+6,6 %+1,7 %
    Communication Services+2,2 %−5,5 %+1,6 %
    Energy+0,6 %+3,3 %+0,0 %
    Health Care · THIS SECTOR+0,6 %−0,8 %+0,0 %
    Information Technology+0,6 %+6,7 %+0,0 %
    Consumer Discretionary+0,4 %+7,6 %−0,2 %
    Financials−0,3 %−2,8 %−0,9 %
    Consumer Staples−0,4 %+2,5 %−1,0 %
    Real Estate−0,7 %+10,9 %−1,3 %
    Industrials−1,9 %−3,1 %−2,5 %
    Utilities−1,9 %+28,2 %−2,5 %

    Developing storylines

    No tracked sagas currently linked to GUTS.O. Browse all sagas →

    Analysis

    AI analysis
    Generated · analysis pipeline · tier hybrid · as of 2026-08-04 ↑ At a glance

    Opportunity

    — missing data

    Upcoming catalysts

    Scheduled public events. Informational only — not investment advice.

    • Company
    • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
    • Macro
    • Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
    • Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
    • Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
    • Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
    • Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
    • Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
    • Macro & political
    • ElectionSE Swedish Election2026-09-14 · SE
    • ElectionUS U.S. Midterms2026-11-03 · US
    • ElectionFR French Legislative2027-06-01 · FR

    Pre-earnings brief

    — missing data

    Signals & dispatch

    peak dispatch · —

    Composite-score breakdown

    Synthesis

    Business

    Fractyl Health Inc (GUTS.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.

    Classification92 %
    SectorHealthcare
    Business sectorPharmaceuticals & Medical Research
    IndustryBiotechnology & Medical Research
    ActivityPharmaceuticals & Medical Research
    AI synthesis
    GENERATED

    Fractyl Health Inc operates with a strong liquidity position, as evidenced by its cash and equivalents of $121.44 million, which significantly exceeds its total liabilities of $79.34 million, resulting in a current ratio of 9.38. The company's debt-to-equity ratio of 0.34 indicates a conservative capital structure, with long-term debt of $28.70 million compared to total equity of $84.18 million. Despite this, the company's negative operating cash flow of -$11.71 million and free cash flow of -$6.07 million suggest ongoing operational challenges.

    In terms of profitability, Fractyl Health Inc reported a net loss of $3.32 million and an operating loss of $21.54 million for the period, resulting in a negative return on equity of -3.95% and a negative return on assets of -2.03%. These figures are below the industry median for biotechnology firms, which typically report positive returns on equity and assets, indicating that the company is underperforming relative to its peers.

    The company's revenue of $33.00 million is concentrated in a single business segment, with no disclosed geographic diversification. This lack of diversification increases the company's exposure to market-specific risks, particularly in the healthcare sector, where regulatory and reimbursement changes can significantly impact revenue.

    Looking ahead, Fractyl Health Inc is projected to maintain its current revenue trajectory, with no significant growth expected in the next fiscal year. The company's operating losses are expected to persist, driven by high R&D and capital expenditures. The negative operating cash flow and free cash flow indicate that the company is not generating sufficient cash to fund its operations, which may necessitate additional financing.

    The risk assessment for Fractyl Health Inc indicates low liquidity and dilution risks, with no immediate filing-based flags detected. However, the company's negative net income and operating cash flow suggest potential financial instability. The dilution risk is currently low, but the company may need to issue additional shares to fund its operations, which could dilute existing shareholders.

    Recent events, including analyst estimates and price targets, suggest a mixed outlook for the company. The mean price target of $5.24 and median price target of $6.20 indicate some optimism among analysts, although the high price target of $8.00 and low price target of $2.00 reflect significant uncertainty. The mean recommendation of 1.80, with two strong-buy and two buy ratings, suggests that some analysts see potential in the company's long-term prospects.

    Key takeaways
    • Fractyl Health Inc has a strong liquidity position with a current ratio of 9.38 and cash and equivalents of $121.44 million.
    • The company is currently unprofitable, with a net loss of $3.32 million and an operating loss of $21.54 million.
    • Revenue is concentrated in a single business segment, increasing exposure to market-specific risks.
    • Analysts have a mixed outlook, with a mean price target of $5.24 and a mean recommendation of 1.80.
    • The company's negative operating cash flow and free cash flow indicate ongoing operational challenges.

    Bull / Bear case

    Generated · model-assisted
    — missing data

    In focus — financials by report

    Quarterly
    Annual
    QUARTERLYFiled 2026-05-12
    Q1 2026 · Quarter highlights
    Open report →

    Revenue $0.00, −100,0% YoY; Operating income +7,6% YoY.

    Revenue$0.00−100,0 % YoY
    Operating income-$23.3M+7,6 % YoY
    Net income-$43.7M−75,1 % YoY
    Free cash flow-$43.5M−73,9 % YoY
    EPS
    Operating cash flow-$90.3M−37,9 % YoY
    Financials
    Income statement
    Revenue$0.00
    Gross profit$0.00
    Operating income-$23.3M
    Net income-$43.7M
    Balance sheet
    Total assets$121.4M
    Total liabilities$111.9M
    Total equity$9.5M
    Cash & equivalents$81.5M
    Long-term debt$30.6M
    Cash flow
    Operating cash flow-$90.3M
    CapEx-$557.0k
    Free cash flow-$43.5M
    SBC
    Highlights
    • Revenue $0.00, −100,0% YoY
    • Operating income +7,6% YoY
    • Net income −75,1% YoY
    • Free cash flow −73,9% YoY

    Valuation TTM

    Market price
    $0,78
    Market cap
    $151.4M
    Enterprise value
    $58.6M
    P/E
    Non-GAAP P/E
    EV / Revenue
    EV / Op income
    EV / OCF
    P / B
    1.8x
    P / Tangible book
    1.8x
    Tangible book
    $84.2M
    Net cash
    $92.7M
    Current ratio
    9.4
    Debt / equity
    0.3
    ROA
    -2.0%
    ROE
    -4.0%
    Cash conversion
    353.0%
    CapEx / revenue
    -32.1%
    SBC / revenue
    Dilution ratio
    0.0%

    Revenue by segment

    Market share

    — missing data

    Business relationships

    — missing data

    Supply chain

    — missing data

    Peer comparison

    — missing data

    Market position

    Stress test

    — missing data

    Predictor forecast

    Next quarternear-term
    Earnings · next quarterconf 66 %
    EPS
    Consensus EPS
    -0,37
    Predicted surprise
    +0,08
    Beat probability
    66 %
    Analysts
    5
    Other metrics
    Revenue
    no estimate
    Segment revenue
    no estimate
    Margin
    no estimate
    Segment margin
    no estimate
    revision ratio 0,43 · as of 2026-05-17 · Earnings Surprise V1
    Period note: consensus is not fiscal-period-aligned at source — read as consensus vs the last reported actual, not a calibrated same-quarter surprise.
    Full fiscal year~1 year ahead
    Full fiscal year · our forecast vs guidance vs consensus
    MetricOur forecastGuidanceConsensus
    EPSno estimateno estimate-0,37
    Revenueno estimateno estimate0 USD
    Operating incomeno estimateno estimate-90,5M USD
    Full-year consensus mean (period as reported by source) · consensus in USD. Company-level full-year forecast and management guidance are not yet modelled at scale — shown as "no estimate", never inferred.
    Probabilistic model output — not investment advice. · generated 2026-08-04

    Options

    — missing data

    Short squeeze

    — missing data

    Earnings-call key lines

    — missing data

    Consensus distribution

    sell-side coverage
    Recommendation distribution5 analysts
    Strong buy2
    Buy2
    Hold1
    Sell0
    Strong sell0
    12-month price target$5,24 · Median $6,20
    Low $2,00High $8,00
    Operating income · consensus-90,5M USD
    EPS surprise
    −400,0 %
    reported vs consensus · miss

    Estimate revisions

    consensus EPS · 26-week trend
    — missing data

    Sell-side observations

    Low$2,00
    Mean$5,24
    Median$6,20
    High$8,00
    Spot$0,78
    +576.0 %implied to mean12-month sell-side price targets · ▲ spot

    Themes

    — missing data

    ESG

    — missing data

    Risk factors

    Dilution riskLow
    Liquidity riskLow
    Filing-based flags
    • No immediate filing-based liquidity or dilution flags were detected.

    Benchmarks vs cohort

    Op Margin-65 278,8 %Bottom quartile
    Net Margin-10 066,7 %Bottom quartile
    ROE-4,0 %Above median
    Capex / Rev-3 209,1 %Bottom quartile
    D/E0,34Bottom quartile
    Cash Conv3,53Best in class

    Corporate actions / M&A

    — missing data

    FX exposure

    — missing data

    Comparable transactions

    — missing data

    Derivatives & instruments

    Derivative transactions

    Net acquired 5 382 241 sh14 grants12 insiders
    • BRADLEY WILLIAMDirector · Stock Option → Common StockAcquired 22 500 @ $0,73grant · 2026-06-10
    • Royan AjayDirector · Stock Option → Common StockAcquired 22 500 @ $0,73grant · 2026-06-10
    • Conaway SamuelDirector · Stock Option → Common StockAcquired 22 500 @ $0,73grant · 2026-06-10
    • Thompson Christopher CharlesDirector · Stock Option → Common StockAcquired 22 500 @ $0,73grant · 2026-06-10
    • Elia MarcDirector · Stock Option → Common StockAcquired 22 500 @ $0,73grant · 2026-06-10
    • Barnes Kelly AnnDirector · Stock Option → Common StockAcquired 22 500 @ $0,73grant · 2026-06-10
    • MEANWELL CLIVEDirector · Stock Option → Common StockAcquired 22 500 @ $0,73grant · 2026-06-10
    • Sheffield IanDirector · Stock Option → Common StockAcquired 22 500 @ $0,73grant · 2026-06-10
    • Smith Weber LaraChief Financial Officer · Stock Option → Common StockAcquired 1 036 800 @ $2,00grant · 2026-01-12
    • Toomey SarahGeneral Counsel · Stock Option (right to buy) → Common StockAcquired 743 913 @ $2,24grant · 2025-12-15
    • Caplan Jay DavidPresident, Chief Product Off. · Stock Option (right to buy) → Common StockAcquired 845 226 @ $2,24grant · 2025-12-15
    • Rajagopalan HarithDirector, Chief Executive Officer · Stock Option (right to buy) → Common StockAcquired 2 486 302 @ $2,24grant · 2025-12-15
    • Thompson Christopher CharlesDirector · Stock Option → Common StockAcquired 45 000 @ $0,98grant · 2025-09-02
    • Sheffield IanDirector · Stock Option → Common StockAcquired 45 000 @ $0,98grant · 2025-09-02

    Actions

    Ask Handelsavisen

    — missing data
    Data sources
    • Market data
    • Market data cache
    • Issuer disclosures
    • Public news
    • Earnings transcripts
    • Consensus estimates
    • ESG data
    How metrics are computed
    • Return On Equity
      net_income / total_equity
    • Price To Book
      market_price / (adjusted_book_value / shares_outstanding_diluted)
    • Dilution Ratio
      (shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
    • Market Price
      input from market-data provider (delayed close or quote-shim mid)
    • Market Cap
      market_price * shares_outstanding_diluted
    • Ev To Revenue
      enterprise_value / revenue
    Source documents
    • Fractyl Health Inc Market data — financials · 2026-05-28
    • Fractyl Health Inc Market data — analyst estimates · 2026-05-28
    • Fractyl Health Inc Market data — ESG · 2026-05-28

    Ownership & reference

    Top holders

    • Vanguard Capital Management, LLCInvestment Managers · as of 2025-12-310,00 %$13M
    • UBS Financial Services, Inc.Investment Managers · as of 2026-03-310,00 %$1M
    • Nuveen LLCInvestment Managers · as of 2024-12-310,00 %$0M
    • Geode Capital Management, L.L.C.Investment Managers · as of 2026-03-310,00 %$1M
    • BlackRock Institutional Trust Company, N.A.Investment Managers · as of 2024-06-300,00 %$2M
    • Morgan Stanley Smith Barney LLCInvestment Managers · as of 2026-03-310,00 %$0M
    • Northern Trust Investments, Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • State Street Investment Management (US)Investment Managers · as of 2026-03-310,00 %$0M
    • Goldman Sachs Asset Management, L.P.Investment Managers · as of 2026-03-310,00 %$0M
    • Victory Capital Management Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • Raymond James & Associates, Inc.Brokerage Firms · as of 2026-03-310,00 %$0M
    • Wells Fargo AdvisorsBrokerage Firms · as of 2026-03-310,00 %$0M
    • LPL Financial LLCInvestment Managers · as of 2026-03-310,00 %$0M
    • Bank of New York Mellon CorpInstitutional Investor · as of 2026-03-310,00 %$0M
    • JONES FINANCIAL COMPANIES LLLPInstitutional Investor · as of 2026-03-310,00 %$0M

    Insider activity

    Net buying6 buys · 0 sellsnet $147K5 insiders · last 365d
    • Royan AjayDirector · Common StockBought 23 000 @ $0,85$20K · 2026-06-12
    • Rajagopalan HarithDirector, Chief Executive Officer · Common StockBought 25 000 @ $0,73$18K · 2026-06-10
    • Sheffield IanDirector · Common StockBought 35 000 @ $0,73$26K · 2026-06-10
    • BRADLEY WILLIAMDirector · Common StockBought 68 493 @ $0,73$50K · 2026-06-10
    • Smith Weber LaraChief Financial Officer · Common StockBought 20 000 @ $0,69$14K · 2026-06-08
    • Rajagopalan HarithDirector, Chief Executive Officer · Common StockBought 10 416 @ $1,92$20K · 2025-12-04

    Short positioning

    2.5Mshares short+9.0% vs prior
    1.29days to cover
    50.9%short of daily vol
    500fails-to-deliver
    as of 2026-07-15 · short-interest report (free)

    Geographic breakdown

    — missing data
    Listings · one canonical issuer all listings resolve to the canonical
    GUTS.OCanonical
    NASDAQ · USD

    Intel & risk

    PredictorBeat prob66 %Surprise+0,08Full forecast →
    peak dispatch · —
    OSINT findings
    Dilution riskLow
    Liquidity riskLow
    No immediate filing-based liquidity or dilution flags were detected.

    Evidence & claims

    From filings & derived data
    • Operating income (YoY) (2025-12-31 vs 2024-12-31): -3.5%Derived (calculated)
    • R&D expense (YoY) (2025-12-31 vs 2024-12-31): 5.8%Derived (calculated)
    • Total assets (YoY) (2025-12-31 vs 2024-12-31): 12.3%Derived (calculated)
    • Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): -66.7%Derived (calculated)
    • Total liabilities (YoY) (2025-12-31 vs 2024-12-31): 40.5%Derived (calculated)
    • Return on equity (FY 2025-12-31): -1,490.3%Derived (calculated)
    • Return on assets (FY 2025-12-31): -116.1%Derived (calculated)
    • Current ratio (FY 2025-12-31): 4.78xDerived (calculated)
    • Debt-to-equity (FY 2025-12-31): 11.84xDerived (calculated)
    • Capex (YoY) (2025-12-31 vs 2024-12-31): -68.4%Derived (calculated)
    • Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): 20.9%Derived (calculated)
    • Cost of revenue (YoY) (2025-12-31 vs 2024-12-31): -100.0%Derived (calculated)
    • EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): -14.8%Derived (calculated)
    • EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): -14.8%Derived (calculated)
    • Net income (YoY) (2025-12-31 vs 2024-12-31): -105.2%Derived (calculated)
    • Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -37.9%Derived (calculated)
    • R&D expense (annual): USD 74.54MSEC XBRL filing
    • Net income (annual): USD -140.95MSEC XBRL filing
    • Operating cash flow (annual): USD -90.33MSEC XBRL filing
    • Total assets (annual): USD 121.4MSEC XBRL filing
    • Current liabilities (annual): USD 18.33MSEC XBRL filing
    • Shares outstanding (annual): 153.37MSEC XBRL filing
    • Shareholders' equity (annual): USD 9.46MSEC XBRL filing
    • Cash & equivalents (annual): USD 81.54MSEC XBRL filing
    Showing 24 of 60 surfaced claims.
    Atomic claims from regulatory filings and derived calculations. Provenance shown as source kind only.

    The Thread

    Everything we know, in order
    2026-10-28EVENTUpcomingQ3 2026 earnings (expected) estimated date
    2026-07-29 22:34 UTCEVENTHa Price Listing GUTS remains DEFICIENT (NASDAQ) — cure period. closed below $1.00 for 94 consecutive trading days (last close $0.85). cure deadline 2027-01-17 (172 days remaining).
    2026-06-30 03:38 UTCEARNINGSUpcomingForecast: insider_flow_signal (90d)
    2026-06-30 03:38 UTCEARNINGSUpcomingForecast: earnings_forecast (90d)
    2026-06-12 00:00 UTCINSIDER13 insider transactions — 2026-06 · net buy $127k 8 derivative
    2026-06-12INSIDERRoyan Ajay bought 23.0k sh — Director ~$20k
    2026-06-11FILING8-K filing →
    2026-06-10INSIDERBRADLEY WILLIAM bought 68.5k sh — Director ~$50k
    2026-06-10INSIDERSheffield Ian bought 35.0k sh — Director ~$26k
    2026-06-10INSIDERRajagopalan Harith bought 25.0k sh — Director, Chief Executive Officer ~$18k
    2026-06-10INSIDERBRADLEY WILLIAM acquired 22.5k sh Stock Option — Director
    2026-06-10INSIDERConaway Samuel acquired 22.5k sh Stock Option — Director
    2026-06-10INSIDERElia Marc acquired 22.5k sh Stock Option — Director
    2026-06-10INSIDERBarnes Kelly Ann acquired 22.5k sh Stock Option — Director
    2026-06-10INSIDERSheffield Ian acquired 22.5k sh Stock Option — Director
    2026-06-10INSIDERThompson Christopher Charles acquired 22.5k sh Stock Option — Director
    2026-06-10INSIDERMEANWELL CLIVE acquired 22.5k sh Stock Option — Director
    2026-06-10INSIDERRoyan Ajay acquired 22.5k sh Stock Option — Director
    2026-06-08INSIDERSmith Weber Lara bought 20.0k sh — Chief Financial Officer ~$14k
    2026-06-04FILING8-K filing →
    2026-05-12 16:05 UTCEARNINGSQuarterly results — Q1 2026 Revenue USD 0.0M · Net USD -43.7M
    2026-05-12FILING10-Q filing →
    2026-05-12FILING8-K filing →
    2026-05-11FILING8-K filing →
    2026-04-24FILINGDEF 14A filing →
    2026-03-24 16:01 UTCEARNINGSQuarterly results — Q4 2025 Revenue USD 0.0M · Net USD -45.6M
    2026-03-24 16:01 UTCEARNINGSAnnual results — FY 2026 Revenue USD 0.0M · Net USD -141.0M
    2026-03-24FILING10-K filing →
    2026-03-24FILING8-K filing →
    2026-03-17FILING8-K filing →
    2026-02-26FILING8-K filing →
    2026-01-29FILING8-K filing →
    2026-01-12 00:00 UTCINSIDER1 insider transaction — 2026-01 1 derivative
    2026-01-12INSIDERSmith Weber Lara acquired 1.04M sh Stock Option — Chief Financial Officer
    2026-01-06FILING8-K filing →
    2025-12-15 00:00 UTCINSIDER4 insider transactions — 2025-12 3 derivative
    2025-12-15INSIDERCaplan Jay David acquired 845.2k sh Stock Option (right to buy) — President, Chief Product Off.
    2025-12-15INSIDERRajagopalan Harith acquired 2.49M sh Stock Option (right to buy) — Director, Chief Executive Officer
    2025-12-15INSIDERToomey Sarah acquired 743.9k sh Stock Option (right to buy) — General Counsel
    2025-12-04INSIDERRajagopalan Harith bought 10.4k sh — Director, Chief Executive Officer ~$20k
    Showing the 40 most recent of 49 entries.
    The entity's full life in the product — typed, chronological, joined across Newspaper, Platform and Data. Our memory, made visible.
    Sources filings · IR · transcripts · market data · tier hybrid · as of 2026-08-04 Market data · Issuer disclosures · Public news · Earnings transcripts · Consensus estimates · ESG data Premium coverage