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INDICATIVE · SAMPLE DATA
HBP56

Helix BioPharma Corp

Biotechnology & Medical ResearchVerified

Helix BioPharma operates with a current liquidity position of CAD 15.59 million in total equity and CAD 3.22 million in total liabilities, yielding a debt-to-equity ratio of 0.02 and a current ratio of 0.13, indicating limited short-term liquidity. The company reported negative operating and free cash flows of CAD 3.83 million and CAD 5.20 million, respectively, in the latest period. Profitability metrics show a return on equity (ROE) of -33.4% and a return on assets (ROA) of -27.7%, both significantly below the industry median for biotechnology firms, which typically report positive ROE and ROA in the 10-20% range. These figures reflect the company's pre-revenue status and high R&D expenditures. The company's revenue is entirely derived from its pipeline of immuno-oncology therapies, with no disclosed geographic diversification in the input data. All revenue is expected to come from the commercialization of its lead candidate, L-DOS47, and pre-IND candidates LEUMUNA and GEMCEDA. Outlook data indicates a continuation of negative operating performance, with no revenue growth expected in the current fiscal year. The company is projected to maintain a negative net income trajectory, with no material change in operating cash flow or free cash flow in the next fiscal year. Risk factors include medium liquidity risk due to negative net cash after subtracting total debt, and low dilution risk based on the current share structure. The company has not disclosed any recent equity issuance or dilutive events in the input data. Recent filings and transcripts highlight the advancement of L-DOS47 into Phase Ib trials and the initiation of pre-IND studies for LEUMUNA and GEMCEDA. No material regulatory or litigation events were disclosed in the input data.

30-day price · HBP+0.07 (+4.6%)
Low$1.46High$2.12Close$1.58As of16 May, 00:00 UTC
Profile
CompanyHelix BioPharma Corp
TickerHBP.TO
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Helix BioPharma Corp is a clinical-stage biopharmaceutical company developing immuno-oncology therapies based on its proprietary DOS47 platform, with a lead candidate L-DOS47 in Phase Ib trials for non-small cell lung cancer.

Classification. Helix BioPharma is classified under the Biotechnology & Medical Research industry within the Healthcare economic sector, with a confidence level of 0.92.

Helix BioPharma operates with a current liquidity position of CAD 15.59 million in total equity and CAD 3.22 million in total liabilities, yielding a debt-to-equity ratio of 0.02 and a current ratio of 0.13, indicating limited short-term liquidity. The company reported negative operating and free cash flows of CAD 3.83 million and CAD 5.20 million, respectively, in the latest period. Profitability metrics show a return on equity (ROE) of -33.4% and a return on assets (ROA) of -27.7%, both significantly below the industry median for biotechnology firms, which typically report positive ROE and ROA in the 10-20% range. These figures reflect the company's pre-revenue status and high R&D expenditures. The company's revenue is entirely derived from its pipeline of immuno-oncology therapies, with no disclosed geographic diversification in the input data. All revenue is expected to come from the commercialization of its lead candidate, L-DOS47, and pre-IND candidates LEUMUNA and GEMCEDA. Outlook data indicates a continuation of negative operating performance, with no revenue growth expected in the current fiscal year. The company is projected to maintain a negative net income trajectory, with no material change in operating cash flow or free cash flow in the next fiscal year. Risk factors include medium liquidity risk due to negative net cash after subtracting total debt, and low dilution risk based on the current share structure. The company has not disclosed any recent equity issuance or dilutive events in the input data. Recent filings and transcripts highlight the advancement of L-DOS47 into Phase Ib trials and the initiation of pre-IND studies for LEUMUNA and GEMCEDA. No material regulatory or litigation events were disclosed in the input data.
Key takeaways
  • Helix BioPharma is a pre-revenue biotechnology company with a clinical-stage pipeline in immuno-oncology.
  • The company's financials reflect significant R&D investment and no current revenue generation.
  • Liquidity is constrained, with a current ratio of 0.13 and negative net cash after debt.
  • The company is advancing multiple candidates but faces high development risk and no near-term revenue visibility.
  • No material dilution risk is currently present, but liquidity constraints may require future capital raises.
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  • ## RATIONALES
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Financial snapshot
PeriodHA-latest
CurrencyCAD
Revenue
Gross profit
Operating income-$5.4M
Net income-$5.2M
R&D
SG&A
D&A
SBC
Operating cash flow-$3.8M
CapEx-$2.0k
Free cash flow-$5.2M
Total assets$18.8M
Total liabilities$3.2M
Total equity$15.6M
Cash & equivalents
Long-term debt$335.0k
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY0
FY-1
FY-2
FY-3
FY-4
PeriodGross %Op %Net %FCF %
FY0
FY-1
FY-2
FY-3
FY-4
PeriodAssetsEquityCashDebt
FY0
FY-1
FY-2
FY-3
FY-4
PeriodOCFCapExFCFSBC
FY0
FY-1
FY-2
FY-3
FY-4
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodGross %Op %Net %FCF %
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodAssetsEquityCashDebt
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodOCFCapExFCFSBC
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
Valuation
Market price
Market cap
Enterprise value
P/E
Reported non-GAAP P/E
EV/Revenue
EV/Op income
EV/OCF
P/B
P/Tangible book
Tangible book$15.6M
Net cash-$335.0k
Current ratio0.1
Debt/Equity0.0
ROA-27.7%
ROE-33.4%
Cash conversion74.0%
CapEx/Revenue
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskMedium
  • Net cash is negative after subtracting total debt.
Industry benchmarks
Activity: Healthcare Diagnostics · cohort 254 companies
MetricHBPActivity
Op margin7.0% medp25 3.8% · p75 10.2%
Net margin2.4% medp25 -0.6% · p75 5.4%
Gross margin50.1% medp25 23.6% · p75 72.3%
CapEx / revenue-6.8% medp25 -27.8% · p75 -1.7%
Debt / equity2.0%140.5% medp25 104.0% · p75 177.0%bottom quartile
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-10 11:39 UTC#d85dfa7b
Source: analysis-pipeline (hybrid)Generated: 2026-05-10 11:40 UTCJob: fb74cd91