Humacyte Inc
Humacyte Inc is a biotechnology company focused on the development and commercialization of bioengineered human tissue products for use in dialysis and other medical applications.
Business. Humacyte Inc (HUMA.O) is a biotechnology and medical research company operating within the healthcare diagnostics industry. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. As no specific operating segments or geographic breakdowns are provided, the company is described at the industry level.
Analyst recommendations
7 analysts · consensus BuyAt a glance
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- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
Humacyte Inc (HUMA.O) is a biotechnology and medical research company operating within the healthcare diagnostics industry. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. As no specific operating segments or geographic breakdowns are provided, the company is described at the industry level.
Humacyte operates with a negative equity position of -$28.29 million and a total asset base of $138.28 million, indicating a capital structure heavily reliant on liabilities, particularly long-term debt of $77.95 million. The company's liquidity position is supported by $93.56 million in cash and equivalents, yielding a current ratio of 5.41, which is strong relative to typical industry norms. However, the company's free cash flow is negative at -$55.07 million, and operating cash flow is -$48.64 million, suggesting ongoing operational cash burn.
Profitability metrics are weak, with a net loss of $56.66 million and an operating loss of $29.50 million. Return on equity is a marginal 2.00%, while return on assets is negative at -0.41%, both of which are below the typical thresholds for a viable biotechnology firm. The company's debt-to-equity ratio is -2.76, which is unusual and reflects the negative equity position, but it does not indicate traditional leverage risk.
The company's revenue is reported as $0, indicating no current commercial operations or product sales. This suggests that Humacyte is in a pre-revenue phase, likely in the development or regulatory approval stage for its bioengineered tissue products. There is no disclosed geographic or segment revenue breakdown, which limits visibility into the company's diversification or concentration risk.
Looking ahead, the company is expected to remain in a pre-revenue phase, with no disclosed growth trajectory or revenue projections. The absence of revenue history and the current financial position suggest that the company is not yet generating value from operations and is likely dependent on capital raising or partnerships to fund ongoing development. The company's future growth is contingent on successful product commercialization and regulatory approvals.
Risk factors include the company's negative equity and ongoing cash burn, which could lead to liquidity constraints if capital raising efforts are not successful. The risk assessment indicates low dilution risk, but the company's reliance on external financing could introduce dilution pressure in the future. No immediate filing-based liquidity or dilution flags were detected, but the company's financial position remains precarious.
Recent events include the absence of disclosed filings or transcripts that would indicate significant corporate developments. The company's price target range is wide, from $1.00 to $25.00, with a mean of $5.07 and a median of $1.50, reflecting analyst uncertainty. The mean recommendation is 2.00, indicating a "buy" rating, but the wide dispersion in price targets suggests a lack of consensus on the company's future value.
- Humacyte is in a pre-revenue phase with no current commercial operations and is likely in the development or regulatory approval stage for its bioengineered tissue products.
- The company has a strong liquidity position with $93.56 million in cash and equivalents, but it is burning cash at a rate of $55.07 million in free cash flow.
- Profitability metrics are weak, with a net loss of $56.66 million and an operating loss of $29.50 million, and the company has a negative return on assets of -0.41%.
- The company's financial position is precarious, with negative equity and a debt-to-equity ratio of -2.76, and its future growth is contingent on successful product commercialization and regulatory approvals.
- Analysts have a wide range of price targets for the company, from $1.00 to $25.00, with a mean of $5.07 and a median of $1.50, indicating significant uncertainty about the company's future value.
Bull / Bear case
Generated · model-assistedAnalysts project 666% upside to a mean price target of $5.07, reflecting strong buy recommendations from seven analysts.
Return on equity of 2.0% ranks best-in-class compared to the biotechnology cohort median of -0.22%.
Free cash flow improved by 76% year-over-year to -$34.4 million in fiscal 2026, indicating reduced cash burn.
The company maintains a healthy current ratio of 3.69, suggesting sufficient short-term liquidity to meet obligations.
Revenue grew at a 12.7% CAGR over four years, reaching $2.04 million in fiscal 2026.
The company faces high credit risk and carries a high leverage band with a debt-to-equity ratio of 11.4.
Net losses widened significantly to $148.7 million in fiscal 2025, demonstrating persistent and growing unprofitability.
Long-term debt increased to $79.9 million in fiscal 2025, rising from $50.5 million in fiscal 2022.
In focus — financials by report
Revenue $495.0k, −4,3% YoY; Operating income −24,8% YoY.
- ▍Revenue $495.0k, −4,3% YoY
- ▍Operating income −24,8% YoY
- ▍Operating margin -5845.5%
Revenue $467.0k; Operating income −89,1% YoY.
- ▍Revenue $467.0k
- ▍Operating income −89,1% YoY
- ▍Net income −18,4% YoY
- ▍Free cash flow −20,1% YoY
- ▍Net margin -5311.3%
Revenue $753.0k; Operating income +19,3% YoY.
- ▍Revenue $753.0k
- ▍Operating income +19,3% YoY
- ▍Net income +55,3% YoY
- ▍Free cash flow +59,0% YoY
- ▍Net margin -2325.4%
Revenue $301.0k; Operating income −0,8% YoY.
- ▍Revenue $301.0k
- ▍Operating income −0,8% YoY
- ▍Net income +33,5% YoY
- ▍Free cash flow +34,0% YoY
- ▍Net margin -12511.0%
Revenue $517.0k; Operating income -$23.2M.
- ▍Revenue $517.0k
- ▍Operating income -$23.2M
- ▍Net margin 7570.4%
Operating income -$28.1M.
- ▍Operating income -$28.1M
Revenue $0.00; Operating income -$30.2M.
- ▍Revenue $0.00
- ▍Operating income -$30.2M
Revenue $0.00; Operating income -$29.5M.
- ▍Revenue $0.00
- ▍Operating income -$29.5M
Revenue $2.0M; Operating income −14,0% YoY.
- ▍Revenue $2.0M
- ▍Operating income −14,0% YoY
- ▍Net income +72,5% YoY
- ▍Free cash flow +76,0% YoY
- ▍Net margin -2003.6%
Operating income −15,1% YoY; Net income −34,2% YoY.
- ▍Operating income −15,1% YoY
- ▍Net income −34,2% YoY
- ▍Free cash flow −35,9% YoY
Revenue $0.00, −100,0% YoY; Operating income −17,5% YoY.
- ▍Revenue $0.00, −100,0% YoY
- ▍Operating income −17,5% YoY
- ▍Net income −825,8% YoY
- ▍Free cash flow −2 092,3% YoY
Revenue $1.6M, +23,9% YoY; Operating income −8,5% YoY.
- ▍Revenue $1.6M, +23,9% YoY
- ▍Operating income −8,5% YoY
- ▍Net income +54,8% YoY
- ▍Free cash flow +74,0% YoY
- ▍Net margin -764.5%
Valuation TTM
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -0,43 |
| Revenue | —no estimate | —no estimate | 10,9M USD |
| Operating income | —no estimate | —no estimate | -82,6M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director, President, CEO and Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director · Stock Options (right to buy) → Common StockAcquired 80 000 @ $1,08grant · 2026-06-11
- Director, President, CEO and Director · Stock Options (right to buy) → Common StockAcquired 311 100 @ $1,23grant · 2025-11-16
- Director · Stock Options (right to buy) → Common StockAcquired 311 100 @ $1,23grant · 2025-11-16
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Market Priceinput from market-data provider (delayed close or quote-shim mid)
- Market Capmarket_price * shares_outstanding_diluted
- Net Cashcash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
- Return On Equitynet_income / total_equity
- Enterprise Valuemarket_cap - net_cash
- Humacyte Inc Market data — financials · 2026-05-28
- Humacyte Inc Market data — analyst estimates · 2026-05-28
- Humacyte Inc Market data — ESG · 2026-05-28
Ownership & reference
Top holders
- Investment Managers · as of 2024-06-300,00 %$34M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2024-12-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$2M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$2M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2025-12-310,00 %$8M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$2M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Funds · as of 2026-03-310,00 %$0M
- Brokerage Firms · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Brokerage Firms · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
Leadership
- Laura NiklasonPresident, Chief Executive Officer, Director
Insider activity
- Director · Common StockBought 56 818 @ $0,88$50K · 2026-05-19
- Director · Common StockBought 11 000 @ $0,89$10K · 2026-05-18
- CFO and Chief Corp. Dev. Off · Common StockSold 45 887 @ $0,90$41K · 2026-05-18
- Chief Medical Officer · Common StockSold 45 887 @ $0,90$41K · 2026-05-18
- Chief Medical Officer · Common StockOther 311 100 · 2025-11-16
- CFO and Chief Corp. Deve. Off. · Common StockOther 311 100 · 2025-11-16
- Director · Common StockSold 591 685 @ $1,58$935K · 2025-08-20
- Director, President, CEO and Director · Common StockSold 591 685 @ $1,58$935K · 2025-08-20
- Director, President, CEO and Director · Common StockSold 1 100 000 @ $1,63$1,8M · 2025-08-19
- Director · Common StockSold 1 100 000 @ $1,63$1,8M · 2025-08-19
- Director · Common StockSold 549 360 @ $1,83$1,0M · 2025-08-18
- Director, President, CEO and Director · Common StockSold 549 360 @ $1,83$1,0M · 2025-08-18
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Operating income (YoY) (2025-12-31 vs 2024-12-31): 5.5%Derived (calculated)
- Total assets (YoY) (2025-12-31 vs 2024-12-31): -15.6%Derived (calculated)
- Net margin (FY 2025-12-31): -2,003.6%Derived (calculated)
- Return on equity (FY 2025-12-31): -1,313.4%Derived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): 72.5%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): 105.9%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -7.1%Derived (calculated)
- R&D expense (YoY) (2025-12-31 vs 2024-12-31): -21.8%Derived (calculated)
- EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 79.4%Derived (calculated)
- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): 12.4%Derived (calculated)
- Capex (YoY) (2025-12-31 vs 2024-12-31): -43.8%Derived (calculated)
- Total liabilities (YoY) (2025-12-31 vs 2024-12-31): -40.6%Derived (calculated)
- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 79.4%Derived (calculated)
- Debt-to-equity (FY 2025-12-31): 36.43xDerived (calculated)
- Current ratio (FY 2025-12-31): 3.69xDerived (calculated)
- Return on assets (FY 2025-12-31): -35.1%Derived (calculated)
- Cash & equivalents (annual): USD 50.5MSEC XBRL filing
- Long-term debt (annual): USD 35.44MSEC XBRL filing
- Total liabilities (annual): USD 113.26MSEC XBRL filing
- EPS (basic) (annual): USD-PER-SHARES -0SEC XBRL filing
- Revenue (annual): USD 2.04MSEC XBRL filing
- Pre-tax income (annual): USD -40.83MSEC XBRL filing
- EPS (diluted) (annual): USD-PER-SHARES -0SEC XBRL filing
- Capex (annual): USD 884KSEC XBRL filing