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INAB.O NASDAQ Biotechnology & Medical Research

IN8bio Inc

$1,38
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Mcap
13,6M USD
P/E
EV / Rev
Div yield
Op margin
ROE
-63,3 %
Net margin
Debt / equity
0,10
Beta
52w range
Volume
7
Day range
Prev close
$1,80
Open
Next earnings
2026-10-28
Ex-dividend
TR 1Y
About

IN8bio Inc is a biotechnology company focused on the development of novel therapeutics for the treatment of cancer and other diseases, primarily through its proprietary platform for the discovery and development of small molecule drugs.

Business. IN8bio Inc (NASDAQ: INAB.O) is a biotechnology company operating within the pharmaceuticals and medical research industry. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.

Classification92 %
SectorHealthcare
Business sectorPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
ActivityPharmaceuticals & Medical Research
Generated · model-assisted
Sell-side consensus
BUY4 analysts
4 buy0 hold0 sell
Avg 12m price target6,25

Analyst recommendations

4 analysts · consensus Buy
Buy4
Hold0
Sell0
12-month price target
6,25
Consensus of sell-side coverage.
Upcoming events
  • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
See all catalysts →

At a glance

Score
not yet scored
Valuation
valuation pending
Analysts
Buy
4 analysts · indicative
Ownership
Franklin Advisers, Inc.
largest disclosed fund holder
Profitability
-63,3 %
return on equity
Quality
not yet scored

What drives this business

The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.

— missing data

News & coverage

0
  • No recent newsroom coverage mentioning INAB.
  • Sector rotation

    Sector1D1Mvs mkt
    Materials+2,3 %+6,6 %+1,7 %
    Communication Services+2,2 %−5,5 %+1,6 %
    Energy+0,6 %+3,3 %+0,0 %
    Health Care · THIS SECTOR+0,6 %−0,8 %+0,0 %
    Information Technology+0,6 %+6,7 %+0,0 %
    Consumer Discretionary+0,4 %+7,6 %−0,2 %
    Financials−0,3 %−2,8 %−0,9 %
    Consumer Staples−0,4 %+2,5 %−1,0 %
    Real Estate−0,7 %+10,9 %−1,3 %
    Industrials−1,9 %−3,1 %−2,5 %
    Utilities−1,9 %+28,2 %−2,5 %

    Developing storylines

    No tracked sagas currently linked to INAB.O. Browse all sagas →

    Analysis

    AI analysis
    Generated · analysis pipeline · tier hybrid · as of 2026-08-04 ↑ At a glance

    Opportunity

    — missing data

    Upcoming catalysts

    Scheduled public events. Informational only — not investment advice.

    • Company
    • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
    • Macro
    • Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
    • Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
    • Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
    • Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
    • Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
    • Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
    • Macro & political
    • ElectionSE Swedish Election2026-09-14 · SE
    • ElectionUS U.S. Midterms2026-11-03 · US
    • ElectionFR French Legislative2027-06-01 · FR

    Pre-earnings brief

    — missing data

    Signals & dispatch

    peak dispatch · —

    Composite-score breakdown

    Synthesis

    Business

    IN8bio Inc (NASDAQ: INAB.O) is a biotechnology company operating within the pharmaceuticals and medical research industry. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.

    Classification92 %
    SectorHealthcare
    Business sectorPharmaceuticals & Medical Research
    IndustryBiotechnology & Medical Research
    ActivityPharmaceuticals & Medical Research
    AI synthesis
    GENERATED

    IN8bio operates with a market capitalization of $15.66 million and a price-to-book ratio of 1.15, indicating that the market values the company slightly above its book value. The company's liquidity position is characterized by a current ratio of 2.66, suggesting it has sufficient short-term assets to cover its liabilities. However, the company's operating cash flow is negative at -$14.01 million, and its free cash flow is also negative at -$8.29 million, indicating a lack of cash generation from operations.

    Profitability metrics show that IN8bio is currently unprofitable, with a net income of -$8.63 million and an operating income of -$8.69 million. The company's return on equity is -63.35%, and its return on assets is -38.36%, both of which are significantly below the industry median for biotechnology firms. The debt-to-equity ratio is 0.1, indicating a relatively low level of leverage compared to industry peers.

    IN8bio's revenue is not disclosed in the provided data, and the company does not report segment or geographic revenue breakdowns. As a pre-revenue biotechnology firm, the company's operations are likely concentrated in research and development, with no significant geographic diversification. The absence of revenue concentration data suggests that the company is in an early stage of development and has not yet commercialized its products.

    The company's growth trajectory is uncertain, as it has not yet achieved profitability and is experiencing negative cash flows. The outlook for the current fiscal year is not provided, but the company's operating performance suggests a challenging path to growth. The absence of revenue history and the lack of positive cash flow metrics indicate that the company is in a high-risk, high-revenue-growth phase.

    Risk factors for IN8bio include its negative net cash position after subtracting total debt, which raises concerns about its ability to fund operations without additional financing. The company's liquidity risk is rated as medium, and while dilution risk is currently low, the need for further capital could increase the risk of equity dilution in the future. The company has not disclosed any recent events such as filings or transcripts that would provide additional insight into its operations or strategic direction.

    Recent investor sentiment, as reflected in analyst estimates, is cautiously optimistic. The mean price target is $6.25, with a median of $5.50, and the highest price target is $10.00. The mean recommendation is 2.00, indicating a "Buy" rating, with four analysts issuing a "Buy" recommendation and none issuing a "Strong Buy".

    Key takeaways
    • IN8bio is a pre-revenue biotechnology company with significant negative cash flows and unprofitability.
    • The company's liquidity position is moderate, with a current ratio of 2.66, but it has a negative operating cash flow of -$14.01 million.
    • The company's return on equity and return on assets are significantly negative, indicating poor capital efficiency.
    • The company's growth trajectory is uncertain, with no revenue history and a lack of positive cash flow metrics.
    • Analysts have a cautiously optimistic outlook, with a mean price target of $6.25 and a "Buy" recommendation.

    Bull / Bear case

    Generated · model-assisted
    — missing data

    In focus — financials by report

    Quarterly
    Annual
    QUARTERLYFiled 2026-05-07
    Q1 2026 · Quarter highlights
    Open report →

    Operating income +7,0% YoY; Net income +8,3% YoY.

    Revenue
    Operating income-$5.3M+7,0 % YoY
    Net income-$5.1M+8,3 % YoY
    Free cash flow-$4.7M+5,3 % YoY
    EPS
    Operating cash flow-$4.9M−58,5 % YoY
    Financials
    Income statement
    Revenue
    Gross profit
    Operating income-$5.3M
    Net income-$5.1M
    Balance sheet
    Total assets$26.3M
    Total liabilities$3.5M
    Total equity$22.8M
    Cash & equivalents
    Long-term debt$189.0k
    Cash flow
    Operating cash flow-$4.9M
    CapEx-$9.0k
    Free cash flow-$4.7M
    SBC
    Highlights
    • Operating income +7,0% YoY
    • Net income +8,3% YoY
    • Free cash flow +5,3% YoY

    Valuation TTM

    Market price
    $1,38
    Market cap
    $15.7M
    Enterprise value
    $17.1M
    P/E
    Non-GAAP P/E
    EV / Revenue
    EV / Op income
    EV / OCF
    P / B
    1.1x
    P / Tangible book
    1.1x
    Tangible book
    $13.6M
    Net cash
    -$1.4M
    Current ratio
    2.7
    Debt / equity
    0.1
    ROA
    -38.4%
    ROE
    -63.3%
    Cash conversion
    162.0%
    CapEx / revenue
    SBC / revenue
    Dilution ratio
    0.0%

    Revenue by segment

    Market share

    — missing data

    Business relationships

    — missing data

    Supply chain

    — missing data

    Peer comparison

    — missing data

    Market position

    Stress test

    — missing data

    Predictor forecast

    Next quarternear-term
    Earnings · next quarterconf 62 %
    EPS
    Consensus EPS
    -1,63
    Predicted surprise
    +0,08
    Beat probability
    62 %
    Analysts
    4
    Other metrics
    Revenue
    no estimate
    Segment revenue
    no estimate
    Margin
    no estimate
    Segment margin
    no estimate
    revision ratio 0,35 · as of 2026-05-17 · Earnings Surprise V1
    Period note: consensus is not fiscal-period-aligned at source — read as consensus vs the last reported actual, not a calibrated same-quarter surprise.
    Full fiscal year~1 year ahead
    Full fiscal year · our forecast vs guidance vs consensus
    MetricOur forecastGuidanceConsensus
    EPSno estimateno estimate-1,63
    Revenueno estimateno estimate0 USD
    Operating incomeno estimateno estimate-23,2M USD
    Full-year consensus mean (period as reported by source) · consensus in USD. Company-level full-year forecast and management guidance are not yet modelled at scale — shown as "no estimate", never inferred.
    Probabilistic model output — not investment advice. · generated 2026-08-04

    Options

    — missing data

    Short squeeze

    — missing data

    Earnings-call key lines

    — missing data

    Consensus distribution

    sell-side coverage
    Recommendation distribution4 analysts
    Strong buy0
    Buy4
    Hold0
    Sell0
    Strong sell0
    12-month price target$6,25 · Median $5,50
    Low $4,00High $10,00
    Operating income · consensus-23,2M USD
    EPS surprise
    −172,4 %
    reported vs consensus · miss

    Estimate revisions

    consensus EPS · 26-week trend
    — missing data

    Sell-side observations

    Low$4,00
    Mean$6,25
    Median$5,50
    High$10,00
    Spot$1,38
    +352.9 %implied to mean12-month sell-side price targets · ▲ spot

    Themes

    — missing data

    ESG

    — missing data

    Risk factors

    Dilution riskLow
    Liquidity riskMedium
    Filing-based flags
    • Net cash is negative after subtracting total debt.

    Benchmarks vs cohort

    ROE-63,3 %Bottom quartile
    D/E0,10Below median
    Cash Conv1,62Best in class

    Corporate actions / M&A

    — missing data

    FX exposure

    — missing data

    Comparable transactions

    — missing data

    Derivatives & instruments

    Derivative transactions

    Net acquired 867 750 sh13 grants9 insiders
    • McCall PatrickCHIEF FINANCIAL OFFICER · Employee Stock Option (right to buy) → Common StockAcquired 56 250 @ $1,58grant · 2026-05-09
    • Epperly CorinneDirector · Stock Option (right to buy) → Common StockAcquired 22 000 @ $1,58grant · 2026-05-09
    • Greenwood LubaDirector · Stock Option (right to buy) → Common StockAcquired 22 000 @ $1,58grant · 2026-05-09
    • Lamb LawrenceEVP and CSO · Employee Stock Option (right to buy) → Common StockAcquired 54 000 @ $1,58grant · 2026-05-09
    • FAIRBAIRN EMILYDirector · Stock Option (right to buy) → Common StockAcquired 22 000 @ $1,58grant · 2026-05-09
    • Rochlin KatePresident and COO · Employee Stock Option (right to buy) → Common StockAcquired 60 000 @ $1,58grant · 2026-05-09
    • Ho William Tai-WeiDirector, CEO · Employee Stock Option (right to buy) → Common StockAcquired 154 500 @ $1,58grant · 2026-05-09
    • Brandt Peter C.Director · Stock Option (right to buy) → Common StockAcquired 22 000 @ $1,58grant · 2026-05-09
    • Graff Jeremy R.Director · Stock Option (right to buy) → Common StockAcquired 22 000 @ $1,58grant · 2026-05-09
    • Ho William Tai-WeiDirector, CEO, 10% owner · Employee Stock Option (right to buy) → Common StockAcquired 206 000 @ $1,96grant · 2026-02-04
    • McCall PatrickCHIEF FINANCIAL OFFICER · Employee Stock Option (right to buy) → Common StockAcquired 75 000 @ $1,96grant · 2026-02-04
    • Lamb LawrenceEVP and CSO · Employee Stock Option (right to buy) → Common StockAcquired 72 000 @ $1,96grant · 2026-02-04
    • Rochlin KatePresident and COO · Employee Stock Option (right to buy) → Common StockAcquired 80 000 @ $1,96grant · 2026-02-04

    Actions

    Ask Handelsavisen

    — missing data
    Data sources
    • Market data
    • Market data cache
    • Issuer disclosures
    • Public news
    • Earnings transcripts
    • Consensus estimates
    • ESG data
    How metrics are computed
    • Return On Equity
      net_income / total_equity
    • Price To Book
      market_price / (adjusted_book_value / shares_outstanding_diluted)
    • Dilution Ratio
      (shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
    • Market Price
      input from market-data provider (delayed close or quote-shim mid)
    • Market Cap
      market_price * shares_outstanding_diluted
    • Net Cash
      cash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
    Source documents
    • IN8bio Inc Market data — financials · 2026-05-28
    • IN8bio Inc Market data — analyst estimates · 2026-05-28

    Ownership & reference

    Top holders

    • Franklin Advisers, Inc.Investment Managers · as of 2026-03-310,00 %$1M
    • Geode Capital Management, L.L.C.Investment Managers · as of 2026-03-310,00 %$0M
    • Northern Trust Investments, Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • BlackRock Institutional Trust Company, N.A.Investment Managers · as of 2024-06-300,00 %$0M
    • Vanguard Capital Management, LLCInvestment Managers · as of 2025-12-310,00 %$0M
    • JONES FINANCIAL COMPANIES LLLPInstitutional Investor · as of 2026-03-310,00 %$0M
    • UBS Financial Services, Inc.Investment Managers · as of 2026-03-310,00 %$0M

    Insider activity

    Mixed / flat0 buys · 0 sellsnet $06 insiders · last 365d
    • FAIRBAIRN EMILYDirector · Common StockOther 724 637 · 2026-05-27
    • Brandt Peter C.Director · Common StockOther 72 464 @ $1,38$100K · 2025-12-22
    • Rochlin KateChief Operating Officer · Common StockOther 7 247 @ $1,38$10K · 2025-12-22
    • McCall PatrickCHIEF FINANCIAL OFFICER · Common StockOther 7 247 @ $1,38$10K · 2025-12-22
    • Ho William Tai-WeiDirector, PRESIDENT AND CEO, 10% owner · Common StockOther 36 232 @ $1,38$50K · 2025-12-22
    • Roemer Alan S.Director · Common StockOther 36 232 @ $1,38$50K · 2025-12-22
    • FAIRBAIRN EMILYDirector · Common StockOther 724 637 @ $1,38$1 000K · 2025-12-22

    Short positioning

    20.8Kshares short-40.8% vs prior
    1days to cover
    37.4%short of daily vol
    7.5Kfails-to-deliver
    as of 2026-07-15 · short-interest report (free)

    Geographic breakdown

    — missing data
    Listings · one canonical issuer all listings resolve to the canonical
    INAB.OCanonical
    NASDAQ · USD

    Intel & risk

    PredictorBeat prob62 %Surprise+0,08Full forecast →
    peak dispatch · —
    OSINT findings
    Dilution riskLow
    Liquidity riskMedium
    Net cash is negative after subtracting total debt.

    Evidence & claims

    From filings & derived data
    • Return on equity (FY 2025-12-31): -70.5%Derived (calculated)
    • Return on assets (FY 2025-12-31): -60.2%Derived (calculated)
    • Debt-to-equity (FY 2025-12-31): 0.17xDerived (calculated)
    • Net income (YoY) (2025-12-31 vs 2024-12-31): 36.1%Derived (calculated)
    • Total liabilities (YoY) (2025-12-31 vs 2024-12-31): -26.9%Derived (calculated)
    • Total assets (YoY) (2025-12-31 vs 2024-12-31): 54.1%Derived (calculated)
    • Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): 90.3%Derived (calculated)
    • R&D expense (YoY) (2025-12-31 vs 2024-12-31): -39.8%Derived (calculated)
    • Operating income (YoY) (2025-12-31 vs 2024-12-31): 36.1%Derived (calculated)
    • Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): 47.4%Derived (calculated)
    • EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 74.0%Derived (calculated)
    • EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 74.0%Derived (calculated)
    • Current ratio (FY 2025-12-31): 8.82xDerived (calculated)
    • EPS (basic) (annual): USD-PER-SHARES -4SEC XBRL filing
    • Total operating expenses (annual): USD 19.86MSEC XBRL filing
    • Net income (annual): USD -19.44MSEC XBRL filing
    • Current assets (annual): USD 27.88MSEC XBRL filing
    • Total liabilities (annual): USD 4.72MSEC XBRL filing
    • Current liabilities (annual): USD 3.16MSEC XBRL filing
    • Shares outstanding (annual): 9.77MSEC XBRL filing
    • Pre-tax income (annual): USD -19.44MSEC XBRL filing
    • R&D expense (annual): USD 10.21MSEC XBRL filing
    • EPS (diluted) (annual): USD-PER-SHARES -4SEC XBRL filing
    • Operating cash flow (annual): USD -12.71MSEC XBRL filing
    Showing 24 of 60 surfaced claims.
    Atomic claims from regulatory filings and derived calculations. Provenance shown as source kind only.

    The Thread

    Everything we know, in order
    2026-10-28EVENTUpcomingQ3 2026 earnings (expected) estimated date
    2026-06-30 03:38 UTCEARNINGSUpcomingForecast: earnings_forecast (90d)
    2026-06-01FILING8-K filing →
    2026-06-01FILING424B5 filing →
    2026-05-27 00:00 UTCINSIDER10 insider transactions — 2026-05 9 derivative
    2026-05-27INSIDERFAIRBAIRN EMILY transacted 724.6k sh — Director
    2026-05-09INSIDERRochlin Kate acquired 60.0k sh Employee Stock Option (right to buy) — President and COO
    2026-05-09INSIDEREpperly Corinne acquired 22.0k sh Stock Option (right to buy) — Director
    2026-05-09INSIDERHo William Tai-Wei acquired 154.5k sh Employee Stock Option (right to buy) — Director, CEO
    2026-05-09INSIDERGreenwood Luba acquired 22.0k sh Stock Option (right to buy) — Director
    2026-05-09INSIDERLamb Lawrence acquired 54.0k sh Employee Stock Option (right to buy) — EVP and CSO
    2026-05-09INSIDERFAIRBAIRN EMILY acquired 22.0k sh Stock Option (right to buy) — Director
    2026-05-09INSIDERMcCall Patrick acquired 56.2k sh Employee Stock Option (right to buy) — CHIEF FINANCIAL OFFICER
    2026-05-09INSIDERBrandt Peter C. acquired 22.0k sh Stock Option (right to buy) — Director
    2026-05-09INSIDERGraff Jeremy R. acquired 22.0k sh Stock Option (right to buy) — Director
    2026-05-07 16:35 UTCEARNINGSQuarterly results — Q1 2026 Net USD -5.1M
    2026-05-07FILING10-Q filing →
    2026-05-07FILING8-K filing →
    2026-03-26FILINGDEF 14A filing →
    2026-03-12 16:01 UTCEARNINGSQuarterly results — Q4 2025 Net USD -4.9M
    2026-03-12 16:01 UTCEARNINGSAnnual results — FY 2026 Net USD -19.4M
    2026-03-12FILING10-K filing →
    2026-03-12FILING8-K filing →
    2026-02-27FILING8-K filing →
    2026-02-09FILING8-K filing →
    2026-02-04 00:00 UTCINSIDER4 insider transactions — 2026-02 4 derivative
    2026-02-04INSIDERRochlin Kate acquired 80.0k sh Employee Stock Option (right to buy) — President and COO
    2026-02-04INSIDERHo William Tai-Wei acquired 206.0k sh Employee Stock Option (right to buy) — Director, CEO, 10% owner
    2026-02-04INSIDERLamb Lawrence acquired 72.0k sh Employee Stock Option (right to buy) — EVP and CSO
    2026-02-04INSIDERMcCall Patrick acquired 75.0k sh Employee Stock Option (right to buy) — CHIEF FINANCIAL OFFICER
    2026-01-30FILING424B3 filing →
    2025-12-22 00:00 UTCINSIDER6 insider transactions — 2025-12 · net buy $1.2M
    2025-12-22INSIDERBrandt Peter C. transacted 72.5k sh — Director ~$100k
    2025-12-22INSIDERRochlin Kate transacted 7.2k sh — Chief Operating Officer ~$10k
    2025-12-22INSIDERMcCall Patrick transacted 7.2k sh — CHIEF FINANCIAL OFFICER ~$10k
    2025-12-22INSIDERHo William Tai-Wei transacted 36.2k sh — Director, PRESIDENT AND CEO, 10% owner ~$50k
    2025-12-22INSIDERRoemer Alan S. transacted 36.2k sh — Director ~$50k
    2025-12-22INSIDERFAIRBAIRN EMILY transacted 724.6k sh — Director ~$1000k
    2025-12-19FILING8-K filing →
    2025-11-24FILING8-K filing →
    Showing the 40 most recent of 51 entries.
    The entity's full life in the product — typed, chronological, joined across Newspaper, Platform and Data. Our memory, made visible.
    Sources filings · IR · transcripts · market data · tier hybrid · as of 2026-08-04 Market data · Issuer disclosures · Public news · Earnings transcripts · Consensus estimates · ESG data Premium coverage