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LIXT.O NASDAQ Pharmaceuticals & Medical Research

Lixte Biotechnology Holdings Inc

$6,41
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1D5D1M3M6MYTD1Y5YMax
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Mcap
74,5M USD
P/E
EV / Rev
Div yield
Op margin
ROE
-31,1 %
Net margin
Debt / equity
0,00
Beta
52w range
Volume
Day range
Prev close
$6,42
Open
Next earnings
2026-10-28
Ex-dividend
TR 1Y
About

Lixte Biotechnology Holdings Inc is a biotechnology company focused on the development of novel therapeutics for the treatment of cancer and other diseases, primarily generating revenue through research and development partnerships and grants.

Business. Lixte Biotechnology Holdings Inc (LIXT.O) is a biotechnology company engaged in pharmaceuticals and medical research. The firm is headquartered in the United States and primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.

Classification99 %
SectorHealth Care
Industry groupPharmaceuticals & Medical Research
Generated · model-assisted
Sell-side consensus
consensus pending
— buy— hold— sell
Avg 12m price target
Upcoming events
  • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
See all catalysts →

At a glance

Score
not yet scored
Valuation
valuation pending
Analysts
not yet wired
Ownership
Geode Capital Management, L.L.C.
largest disclosed fund holder
Profitability
-31,1 %
return on equity
Quality
not yet scored

What drives this business

The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.

— missing data

News & coverage

0
  • No recent newsroom coverage mentioning LIXT.
  • Sector rotation

    Sector1D1Mvs mkt
    Materials+2,3 %+6,6 %+1,7 %
    Communication Services+2,2 %−5,5 %+1,6 %
    Energy+0,6 %+3,3 %+0,0 %
    Health Care · THIS SECTOR+0,6 %−0,8 %+0,0 %
    Information Technology+0,6 %+6,7 %+0,0 %
    Consumer Discretionary+0,4 %+7,6 %−0,2 %
    Financials−0,3 %−2,8 %−0,9 %
    Consumer Staples−0,4 %+2,5 %−1,0 %
    Real Estate−0,7 %+10,9 %−1,3 %
    Industrials−1,9 %−3,1 %−2,5 %
    Utilities−1,9 %+28,2 %−2,5 %

    Developing storylines

    No tracked sagas currently linked to LIXT.O. Browse all sagas →

    Analysis

    AI analysis
    Generated · analysis pipeline · tier hybrid · as of 2026-08-04 ↑ At a glance

    Opportunity

    — missing data

    Upcoming catalysts

    Scheduled public events. Informational only — not investment advice.

    • Company
    • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
    • Macro
    • Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
    • Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
    • Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
    • Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
    • Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
    • Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
    • Macro & political
    • ElectionSE Swedish Election2026-09-14 · SE
    • ElectionUS U.S. Midterms2026-11-03 · US
    • ElectionFR French Legislative2027-06-01 · FR

    Pre-earnings brief

    — missing data

    Signals & dispatch

    peak dispatch · —

    Composite-score breakdown

    Synthesis

    Business

    Lixte Biotechnology Holdings Inc (LIXT.O) is a biotechnology company engaged in pharmaceuticals and medical research. The firm is headquartered in the United States and primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.

    Classification99 %
    SectorHealth Care
    Industry groupPharmaceuticals & Medical Research
    AI synthesis
    GENERATED

    Lixte Biotechnology has a market capitalization of $58.55 million and a price-to-book ratio of 18.73, indicating a premium valuation relative to its book value. The company has no long-term debt and a debt-to-equity ratio of 0.0, suggesting a conservative capital structure. Its current ratio of 7.75 indicates strong short-term liquidity, with current assets significantly outpacing current liabilities.

    The company reported a net loss of $971,320 and an operating loss of $966,880 in the latest period, with a return on equity of -31.07% and a return on assets of -27.06%. These metrics indicate poor profitability and asset utilization, falling well below the industry norms for biotechnology firms, which typically require significant R&D investment before achieving profitability.

    Lixte Biotechnology does not disclose segment or geographic revenue breakdowns in its latest financials, making it difficult to assess revenue concentration or geographic exposure. The absence of segment data limits the ability to evaluate the performance of different product lines or regions.

    The company's outlook for the current fiscal year shows no revenue growth, with a net loss expected to continue. The lack of revenue and ongoing operating cash outflows of $789,230 suggest the company is in an early-stage development phase, relying on capital reserves to fund operations. No significant growth in revenue or profitability is anticipated in the near term.

    Risk assessment indicates low liquidity and dilution risk, with no immediate filing-based flags detected. The company has a low probability of near-term dilution, and no dilution sources were identified in the latest filings. However, the ongoing net losses and lack of revenue could necessitate future capital raises, which may involve dilution.

    Recent filings and transcripts do not highlight any major events or strategic shifts. The company remains focused on its pipeline of drug candidates, with no recent public announcements of partnerships, clinical trial results, or regulatory milestones. The absence of recent events suggests a stable but slow-moving development process.

    Key takeaways
    • Lixte Biotechnology is a pre-revenue biotechnology company with a high price-to-book ratio and no long-term debt.
    • The company is currently unprofitable, with significant net and operating losses, and negative returns on equity and assets.
    • No segment or geographic revenue data is available, limiting visibility into business performance.
    • The company is in a development phase with no near-term revenue growth expected.
    • Low liquidity and dilution risk are reported, but ongoing losses may require future capital raises.

    Bull / Bear case

    Generated · model-assisted
    BULL CASE · 4

    The company maintains a zero long-term debt position, resulting in a debt-to-equity ratio of 0.0 and eliminating interest coverage risks.

    Lixte Biotechnology holds a current ratio of 2.09, indicating sufficient short-term liquidity to cover immediate operational obligations.

    Dilution risk is assessed as low, suggesting limited immediate pressure on existing shareholder equity from new share issuance.

    Liquidity risk is rated low, implying the company can likely meet its short-term financial commitments without significant distress.

    BEAR CASE · 2

    The company carries a high credit risk flag, indicating potential difficulties in securing favorable financing or meeting debt obligations.

    The firm generates zero revenue, relying entirely on capital preservation rather than commercial product sales to sustain operations.

    In focus — financials by report

    Valuation FY

    Market price
    $6,41
    Market cap
    $58.6M
    Enterprise value
    P/E
    Non-GAAP P/E
    EV / Revenue
    EV / Op income
    EV / OCF
    P / B
    18.7x
    P / Tangible book
    18.7x
    Tangible book
    $3.1M
    Net cash
    Current ratio
    7.8
    Debt / equity
    0.0
    ROA
    -27.1%
    ROE
    -31.1%
    Cash conversion
    81.0%
    CapEx / revenue
    SBC / revenue
    Dilution ratio
    0.0%

    Revenue by segment

    Market share

    INDUSTRYSEGMENTCOMPANYHealthcareIndustryPharmaceuticals & Medical Research15,2B node revenueKLAR 23,0%BNTX 21,4%EXEL 15,2%MDGL 6,3%INSM 4,0%VCYT 3,4%MDXG 2,8%AVIR 2,3%Other 21,6%
    Source: company disclosures · own-taxonomy revenue-covered setLIXT 0,0% · rank #91 of 109

    Business relationships

    Business relationships1 disclosed relationship · 1 type · extracted from filings & disclosures
    Partners1
    Gsk PLCGSK.LPartner95%Source ↗

    Supply chain

    Vendors → LIXT ↔ Partners → Customers · click any node to drill
    VENDORSPARTNERSCUSTOMERSLIXTLIXTLixte Biotechnology Holdings Inc1 entityGsk PLCPharmaceuticalsGB
    1 mention in 10-K0 from corporate websites0 from news dispatches
    Updated 2026-06-24

    Peer comparison

    Peer comparison8 peers · vs LIXT · multiples and returns
    KL
    KLAR
    KLAR.ST
    P/E
    vs self
    Div yield
    vs self
    ROE
    vs self
    BN
    BNTX
    Biontech SE
    $92,25
    23,3B USD
    P/E
    vs self
    Div yield
    vs self
    ROE
    vs self
    EX
    EXEL
    Exelixis Inc
    $55,06
    14,7B USD
    P/E
    19,5x
    vs self
    Div yield
    vs self
    ROE
    40,4 %
    +71,5 vs self
    MD
    MDGL
    Madrigal Pharmaceuticals Inc
    $482,00
    11,0B USD
    P/E
    vs self
    Div yield
    vs self
    ROE
    -47,8 %
    -16,8 vs self
    IN
    INSM
    Insmed Inc
    $107,46
    23,0B USD
    P/E
    vs self
    Div yield
    vs self
    ROE
    -160,2 %
    -129,1 vs self
    VC
    VCYT
    Veracyte Inc
    $45,30
    3,6B USD
    P/E
    55,5x
    vs self
    Div yield
    vs self
    ROE
    5,1 %
    +36,1 vs self
    MD
    MDXG
    Mimedx Group Inc
    $4,27
    636,0M USD
    P/E
    11,1x
    vs self
    Div yield
    vs self
    ROE
    18,9 %
    +50,0 vs self
    AV
    AVIR
    Atea Pharmaceuticals Inc
    $4,61
    P/E
    vs self
    Div yield
    vs self
    ROE
    -57,5 %
    -26,4 vs self

    Market position

    Stress test

    — missing data

    Predictor forecast

    Options

    — missing data

    Short squeeze

    — missing data

    Earnings-call key lines

    — missing data

    Estimate revisions

    consensus EPS · 26-week trend
    — missing data

    Sell-side observations

    — missing data

    Themes

    — missing data

    ESG

    — missing data

    Risk factors

    Dilution riskLow
    Liquidity riskLow
    Filing-based flags
    • No immediate filing-based liquidity or dilution flags were detected.

    Benchmarks vs cohort

    ROE-31,1 %Below median
    D/E0,00Above median
    Cash Conv0,81Below median

    Corporate actions / M&A

    — missing data

    FX exposure

    — missing data

    Comparable transactions

    — missing data

    Derivatives & instruments

    Derivative transactions

    Net disposed 350 000 sh5 grants6 insiders
    • Felix LourdesDirector · Stock Option (right to buy) → Common StockDisposed 25 000 @ $4,05disposition · 2026-04-15
    • Pursglove Geordan GarrettDirector, CEO and Chairman of the Board · Options to Purchase Common Stock → CommonDisposed 350 000 @ $2,83disposition · 2026-04-15
    • Stazzone PeterChief Financial Officer · Options to Purchase Common Stock → CommonDisposed 50 000 @ $4,45disposition · 2026-04-15
    • Sawyer Jason DavidDirector · Options to Purchase Common Stock → CommonDisposed 25 000 @ $3,59disposition · 2026-04-15
    • Primus Guy WarrenDirector · Stock Option (right to buy) → Common StockDisposed 25 000 @ $4,05disposition · 2026-04-15
    • Holloway Michael AndrewDirector · Options to Purchase Common Stock → CommonDisposed 25 000 @ $3,59disposition · 2026-04-15
    • Felix LourdesDirector · Stock Option (right to buy) → Common StockAcquired 25 000 @ $4,05grant · 2025-12-24
    • Primus Guy WarrenDirector · Stock Option (right to buy) → Common StockAcquired 25 000 @ $4,05grant · 2025-12-24
    • Stazzone PeterChief Financial Officer · Options to Purchase Common Stock → CommonAcquired 50 000 @ $4,45grant · 2025-09-01
    • Sawyer Jason DavidDirector · Options to Purchase Common Stock → CommonAcquired 25 000 @ $3,59grant · 2025-08-15
    • Holloway Michael AndrewDirector · Options to Purchase Common Stock → CommonAcquired 25 000 @ $3,59grant · 2025-08-15

    Actions

    Ask Handelsavisen

    — missing data
    Data sources
    • Market data
    • Market data cache
    • Issuer disclosures
    • Public news
    • Earnings transcripts
    • Consensus estimates
    • ESG data
    How metrics are computed
    • Dilution Ratio
      (shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
    • Market Price
      input from market-data provider (delayed close or quote-shim mid)
    • Market Cap
      market_price * shares_outstanding_diluted
    • Return On Equity
      net_income / total_equity
    • Price To Tangible Book
      market_price / (tangible_book_value / shares_outstanding_diluted)
    • Debt To Equity
      (short_term_debt + long_term_debt) / total_equity
    Source documents
    • Lixte Biotechnology Holdings Inc Market data — financials · 2026-05-28

    Ownership & reference

    Top holders

    • Geode Capital Management, L.L.C.Investment Managers · as of 2026-03-310,00 %$0M
    • Vanguard Capital Management, LLCInvestment Managers · as of 2025-12-310,00 %$0M
    • State Street Investment Management (US)Investment Managers · as of 2026-03-310,00 %$0M

    Insider activity

    Mixed / flat0 buys · 0 sellsnet $07 insiders · last 365d
    • Porter Stuart DDirector · Common StockOther 25 000 · 2026-05-29
    • Primus Guy WarrenDirector · Common StockOther 25 000 · 2026-04-15
    • Pursglove Geordan GarrettDirector, CEO and Chairman of the Board · Common StockOther 350 000 · 2026-04-15
    • Stazzone PeterChief Financial Officer · Common StockOther 50 000 · 2026-04-15
    • Sawyer Jason DavidDirector · Common StockOther 25 000 · 2026-04-15
    • Felix LourdesDirector · Common StockOther 25 000 · 2026-04-15
    • Holloway Michael AndrewDirector · Common StockOther 25 000 · 2026-04-15

    Short positioning

    709.8Kshares short+84.0% vs prior
    1.4days to cover
    54.7%short of daily vol
    20.0Kfails-to-deliver
    as of 2026-06-30 · short-interest report (free)

    Geographic breakdown

    — missing data
    Listings · one canonical issuer all listings resolve to the canonical
    LIXT.OCanonical
    NASDAQ · USD

    Intel & risk

    peak dispatch · —
    OSINT findings
    Dilution riskLow
    Liquidity riskLow
    No immediate filing-based liquidity or dilution flags were detected.
    Relationship graph
    LIXTGSK.LPharmaceutical
    This companySectorPartners

    Evidence & claims

    From filings & derived data
    • Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): 1,068.3%Derived (calculated)
    • EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 20.8%Derived (calculated)
    • Total liabilities (YoY) (2025-12-31 vs 2024-12-31): 456.8%Derived (calculated)
    • Return on equity (FY 2025-12-31): -62.9%Derived (calculated)
    • Return on assets (FY 2025-12-31): -47.7%Derived (calculated)
    • Current ratio (FY 2025-12-31): 3.88xDerived (calculated)
    • Debt-to-equity (FY 2025-12-31): 0.18xDerived (calculated)
    • R&D expense (YoY) (2025-12-31 vs 2024-12-31): -64.9%Derived (calculated)
    • Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): 3.0%Derived (calculated)
    • Net income (YoY) (2025-12-31 vs 2024-12-31): -69.5%Derived (calculated)
    • Total assets (YoY) (2025-12-31 vs 2024-12-31): 1,011.6%Derived (calculated)
    • Operating income (YoY) (2025-12-31 vs 2024-12-31): -43.0%Derived (calculated)
    • Current liabilities (annual): USD 1.33MSEC XBRL filing
    • Total liabilities (annual): USD 1.77MSEC XBRL filing
    • EPS (diluted) (annual): USD-PER-SHARES -1SEC XBRL filing
    • Operating income (annual): USD -5.11MSEC XBRL filing
    • Interest expense (annual): USD 9.16KSEC XBRL filing
    • R&D expense (annual): USD 254.92KSEC XBRL filing
    • Total assets (annual): USD 12.73MSEC XBRL filing
    • Current assets (annual): USD 5.18MSEC XBRL filing
    • Shares outstanding (annual): 8.79MSEC XBRL filing
    • Total operating expenses (annual): USD 5.11MSEC XBRL filing
    • Net income (annual): USD -6.08MSEC XBRL filing
    • Shareholders' equity (annual): USD 9.66MSEC XBRL filing
    Showing 24 of 60 surfaced claims.
    Atomic claims from regulatory filings and derived calculations. Provenance shown as source kind only.

    The Thread

    Everything we know, in order
    2026-10-28EVENTUpcomingQ3 2026 earnings (expected) estimated date
    2026-06-18FILING8-K filing →
    2026-06-16FILING8-K filing →
    2026-06-04FILING8-K filing →
    2026-06-04FILING424B5 filing →
    2026-06-01FILING8-K filing →
    2026-05-29 00:00 UTCINSIDER1 insider transaction — 2026-05
    2026-05-29INSIDERPorter Stuart D transacted 25.0k sh — Director
    2026-05-14FILING10-Q filing →
    2026-04-17FILING8-K filing →
    2026-04-15 00:00 UTCINSIDER12 insider transactions — 2026-04 6 derivative
    2026-04-15INSIDERPrimus Guy Warren transacted 25.0k sh — Director
    2026-04-15INSIDERPursglove Geordan Garrett transacted 350.0k sh — Director, CEO and Chairman of the Board
    2026-04-15INSIDERStazzone Peter transacted 50.0k sh — Chief Financial Officer
    2026-04-15INSIDERSawyer Jason David transacted 25.0k sh — Director
    2026-04-15INSIDERFelix Lourdes transacted 25.0k sh — Director
    2026-04-15INSIDERHolloway Michael Andrew transacted 25.0k sh — Director
    2026-04-15INSIDERSawyer Jason David disposed of 25.0k sh Options to Purchase Common Stock — Director
    2026-04-15INSIDERStazzone Peter disposed of 50.0k sh Options to Purchase Common Stock — Chief Financial Officer
    2026-04-15INSIDERPursglove Geordan Garrett disposed of 350.0k sh Options to Purchase Common Stock — Director, CEO and Chairman of the Board
    2026-04-15INSIDERPrimus Guy Warren disposed of 25.0k sh Stock Option (right to buy) — Director
    2026-04-15INSIDERFelix Lourdes disposed of 25.0k sh Stock Option (right to buy) — Director
    2026-04-15INSIDERHolloway Michael Andrew disposed of 25.0k sh Options to Purchase Common Stock — Director
    2026-03-31FILING10-K filing →
    2026-03-20FILING8-K filing →
    2026-03-10FILING8-K filing →
    2026-02-18FILING8-K filing →
    2025-12-31FILING8-K filing →
    2025-12-24 00:00 UTCINSIDER2 insider transactions — 2025-12 2 derivative
    2025-12-24INSIDERPrimus Guy Warren acquired 25.0k sh Stock Option (right to buy) — Director
    2025-12-24INSIDERFelix Lourdes acquired 25.0k sh Stock Option (right to buy) — Director
    2025-09-01 00:00 UTCINSIDER1 insider transaction — 2025-09 1 derivative
    2025-09-01INSIDERStazzone Peter acquired 50.0k sh Options to Purchase Common Stock — Chief Financial Officer
    2025-08-15 00:00 UTCINSIDER2 insider transactions — 2025-08 2 derivative
    2025-08-15INSIDERHolloway Michael Andrew acquired 25.0k sh Options to Purchase Common Stock — Director
    2025-08-15INSIDERSawyer Jason David acquired 25.0k sh Options to Purchase Common Stock — Director
    2025-07-03 00:00 UTCINSIDER1 insider transaction — 2025-07 1 derivative
    2025-06-30 00:00 UTCINSIDER8 insider transactions — 2025-06 8 derivative
    2025-03-31 00:00 UTCINSIDER1 insider transaction — 2025-03 1 derivative
    The entity's full life in the product — typed, chronological, joined across Newspaper, Platform and Data. Our memory, made visible.
    Sources filings · IR · transcripts · market data · tier hybrid · as of 2026-08-04 Market data · Issuer disclosures · Public news · Earnings transcripts · Consensus estimates · ESG data Premium coverage