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INDICATIVE · SAMPLE DATA
MIST$1.5259

Milestone Pharmaceuticals Inc

Biotechnology & Medical ResearchVerified

Milestone Pharmaceuticals Inc operates with a high liquidity position, as evidenced by a current ratio of 8.01 and cash and equivalents of $73.05 million, which significantly exceeds its total liabilities of $71.79 million. The company's price-to-book ratio of 4.35 suggests that the market is valuing its equity at a premium relative to its book value, which may reflect expectations of future growth or intangible assets. However, the company's liquidity is not supported by strong cash flow generation, as it reported an operating cash flow of -$49.04 million and a free cash flow of -$63.25 million in the latest period. Profitability metrics indicate significant underperformance relative to industry norms. The company reported a net loss of $63.06 million and an operating loss of $62.14 million, resulting in a return on equity of -1.51 and a return on assets of -0.56, both of which are negative and suggest poor capital efficiency. These figures are likely to be below the median for the biotechnology and medical research industry, where positive returns are typically expected for firms in later stages of development. Milestone's revenue is concentrated in a single business line, as the company does not disclose segment-specific revenue data. This lack of diversification increases exposure to market volatility and regulatory changes in the biopharmaceutical sector. The company's geographic exposure is not explicitly detailed, but as a U.S.-listed firm, it is likely to derive the majority of its revenue from North America, with potential international expansion in the pipeline. The company's growth trajectory is uncertain, as it reported revenue of $1.55 million in the latest period, with no indication of significant year-over-year growth. Analysts have provided a wide range of price targets, from $2.00 to $8.00, with a mean of $6.50 and a median of $7.50, suggesting a high degree of uncertainty about the company's future performance. The company's capital expenditures were relatively modest at -$302,000, indicating limited investment in new facilities or equipment. Risk factors include the company's negative net income and operating income, which raise concerns about its ability to sustain operations without additional financing. The debt-to-equity ratio of 1.37 suggests that the company is leveraged, and while there are no immediate liquidity or dilution flags, the risk of future dilution remains a concern given the company's current capital structure. The company's reliance on external financing to fund operations increases its vulnerability to changes in market conditions and investor sentiment. Recent events include the publication of analyst estimates, which show a mean recommendation of 2.00 (on a scale from 1 to 5, where 1 is "strong buy" and 5 is "strong sell"). The company has not disclosed any recent filings or transcripts that would indicate significant changes in its business strategy or financial position.

30-day price · MIST-0.59 (-29.5%)
Low$1.41High$2.34Close$1.41As of22 May, 00:00 UTC
Profile
CompanyMilestone Pharmaceuticals Inc
TickerMIST.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Milestone Pharmaceuticals Inc is a biopharmaceutical company focused on the development and commercialization of novel therapies for the treatment of rare diseases, primarily in the field of oncology.

Classification. Milestone is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a confidence level of 0.92.

Milestone Pharmaceuticals Inc operates with a high liquidity position, as evidenced by a current ratio of 8.01 and cash and equivalents of $73.05 million, which significantly exceeds its total liabilities of $71.79 million. The company's price-to-book ratio of 4.35 suggests that the market is valuing its equity at a premium relative to its book value, which may reflect expectations of future growth or intangible assets. However, the company's liquidity is not supported by strong cash flow generation, as it reported an operating cash flow of -$49.04 million and a free cash flow of -$63.25 million in the latest period. Profitability metrics indicate significant underperformance relative to industry norms. The company reported a net loss of $63.06 million and an operating loss of $62.14 million, resulting in a return on equity of -1.51 and a return on assets of -0.56, both of which are negative and suggest poor capital efficiency. These figures are likely to be below the median for the biotechnology and medical research industry, where positive returns are typically expected for firms in later stages of development. Milestone's revenue is concentrated in a single business line, as the company does not disclose segment-specific revenue data. This lack of diversification increases exposure to market volatility and regulatory changes in the biopharmaceutical sector. The company's geographic exposure is not explicitly detailed, but as a U.S.-listed firm, it is likely to derive the majority of its revenue from North America, with potential international expansion in the pipeline. The company's growth trajectory is uncertain, as it reported revenue of $1.55 million in the latest period, with no indication of significant year-over-year growth. Analysts have provided a wide range of price targets, from $2.00 to $8.00, with a mean of $6.50 and a median of $7.50, suggesting a high degree of uncertainty about the company's future performance. The company's capital expenditures were relatively modest at -$302,000, indicating limited investment in new facilities or equipment. Risk factors include the company's negative net income and operating income, which raise concerns about its ability to sustain operations without additional financing. The debt-to-equity ratio of 1.37 suggests that the company is leveraged, and while there are no immediate liquidity or dilution flags, the risk of future dilution remains a concern given the company's current capital structure. The company's reliance on external financing to fund operations increases its vulnerability to changes in market conditions and investor sentiment. Recent events include the publication of analyst estimates, which show a mean recommendation of 2.00 (on a scale from 1 to 5, where 1 is "strong buy" and 5 is "strong sell"). The company has not disclosed any recent filings or transcripts that would indicate significant changes in its business strategy or financial position.
Key takeaways
  • Milestone Pharmaceuticals Inc has a strong liquidity position but is currently unprofitable, with a net loss of $63.06 million.
  • The company's price-to-book ratio of 4.35 suggests a premium valuation, but this is not supported by positive cash flow generation.
  • Analysts have provided a wide range of price targets, indicating uncertainty about the company's future performance.
  • The company's revenue is concentrated in a single business line, increasing its exposure to market volatility.
  • The company's debt-to-equity ratio of 1.37 suggests a leveraged capital structure, and while there are no immediate liquidity or dilution flags, the risk of future dilution remains a concern.
  • --
  • ## RATIONALES
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Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$1.5M
Gross profit
Operating income-$62.1M
Net income-$63.1M
R&D
SG&A
D&A
SBC
Operating cash flow-$49.0M
CapEx-$302.0k
Free cash flow-$63.2M
Total assets$113.6M
Total liabilities$71.8M
Total equity$41.8M
Cash & equivalents$73.0M
Long-term debt$57.2M
Valuation
Market price$1.52
Market cap$181.8M
Enterprise value$166.0M
P/E
Reported non-GAAP P/E
EV/Revenue107.4
EV/Op income
EV/OCF
P/B4.3
P/Tangible book4.3
Tangible book$41.8M
Net cash$15.9M
Current ratio8.0
Debt/Equity1.4
ROA-55.5%
ROE-1.5%
Cash conversion78.0%
CapEx/Revenue-19.5%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 693 companies
MetricMISTActivity
Op margin-4019.4%2.4% medp25 -91.8% · p75 12.5%bottom quartile
Net margin-4078.8%1.2% medp25 -98.4% · p75 10.4%bottom quartile
Gross margin45.6% medp25 29.8% · p75 66.7%
CapEx / revenue-19.5%-5.2% medp25 -15.8% · p75 -1.7%bottom quartile
Debt / equity137.0%9.3% medp25 0.1% · p75 43.8%top quartile
Observations
IR observations
Mean price target6.50 USD
Median price target7.50 USD
High price target8.00 USD
Low price target2.00 USD
Mean recommendation2.00 (1=strong buy, 5=strong sell)
Strong-buy count1.00
Buy count4.00
Hold count1.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-0.40 USD
Last actual EPS-0.75 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod financials
no public URL
2026-05-22 12:05 UTC#b2cf6575
Source: analysis-pipeline (hybrid)Generated: 2026-05-28 14:12 UTCJob: 42ad329d