Mirm.O
Mirum Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of therapeutics for the treatment of rare and severe liver diseases.
Business. Mirum Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of therapeutics for the treatment of rare and severe liver diseases.
Analyst recommendations
11 analysts · consensus BuyAt a glance
What drives this business
The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
News & coverage
0Sector rotation
Developing storylines
Analysis
AI analysisOpportunity
Upcoming catalysts
Scheduled public events. Informational only — not investment advice.
- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
Mirum Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of therapeutics for the treatment of rare and severe liver diseases.
Mirum Pharmaceuticals has a liquidity position characterized by $296.68 million in cash and equivalents, which is offset by $309.80 million in long-term debt, resulting in a net cash position of -$13.12 million. The company's debt-to-equity ratio of 0.98 suggests a moderate level of leverage, while its current ratio of 2.67 indicates a strong ability to meet short-term obligations.
The company's profitability metrics are concerning, with a return on equity of -7.42% and a return on assets of -2.77%. These figures are below the industry norms for pharmaceutical companies, which typically exhibit positive returns on equity and assets. The negative operating income of $22.14 million and net loss of $23.36 million further underscore the company's current financial challenges.
Mirum Pharmaceuticals operates in a single business segment focused on the development of therapies for rare liver diseases. The company's geographic exposure is primarily concentrated in the United States, with no significant international revenue disclosed. This concentration may expose the company to regulatory and market risks specific to the U.S. healthcare environment.
The company's growth trajectory is uncertain, with no specific revenue growth projections provided in the outlook. However, the negative operating cash flow and free cash flow of $55.83 million and -$73,000, respectively, suggest that the company is not generating sufficient cash from operations to sustain or grow its business without external financing.
The risk assessment for Mirum Pharmaceuticals highlights a medium liquidity risk and a low dilution risk. The key flag of negative net cash after subtracting total debt indicates potential liquidity constraints. The company's dilution risk is considered low, but the negative free cash flow and reliance on operating cash flow suggest that the company may need to raise additional capital in the future, which could lead to share dilution.
Recent events and filings indicate that Mirum Pharmaceuticals is actively engaged in clinical trials and regulatory submissions for its lead candidate, MARZAA (maralixibat). The company has also been in discussions with the U.S. Food and Drug Administration (FDA) regarding the potential approval of MARZAA for the treatment of progressive familial intrahepatic cholestasis (PFIC).
- Mirum Pharmaceuticals has a strong current ratio of 2.67, indicating a solid short-term liquidity position despite a negative net cash position.
- The company's return on equity and return on assets are negative, reflecting poor profitability and underperformance relative to industry standards.
- Mirum Pharmaceuticals operates in a single business segment focused on rare liver diseases, with a primary geographic concentration in the United States.
- The company's negative free cash flow and reliance on operating cash flow suggest a need for external financing to support ongoing operations and growth.
- The risk assessment indicates a medium liquidity risk and a low dilution risk, with the key flag of negative net cash after subtracting total debt being a significant concern.
Bull / Bear case
analysis pipelineIn focus — financials by report
Valuation
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -1,77 |
| Revenue | —no estimate | —no estimate | 644,9M USD |
| Operating income | —no estimate | —no estimate | -79,1M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- Net cash is negative after subtracting total debt.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Director, CHIEF EXECUTIVE OFFICER · Employee Stock Option (right to buy) → Common StockDisposed 20 000 @ $2,94exercise · 2026-07-06
- Director · Restricted Stock Units → Common StockAcquired 1 980grant · 2026-06-15
- Director · Stock Option (right to buy) → Common StockAcquired 3 772 @ $101,00grant · 2026-06-15
- Director · Stock Option (right to buy) → Common StockAcquired 3 772 @ $101,00grant · 2026-06-15
- Director · Stock Option (right to buy) → Common StockAcquired 3 772 @ $101,00grant · 2026-06-15
- Director · Restricted Stock Units → Common StockAcquired 1 980grant · 2026-06-15
- Director · Stock Option (right to buy) → Common StockAcquired 3 772 @ $101,00grant · 2026-06-15
- Director · Restricted Stock Units → Common StockAcquired 1 980grant · 2026-06-15
- Director · Stock Option (right to buy) → Common StockAcquired 3 772 @ $101,00grant · 2026-06-15
- Director · Deferred Stock Units → Common StockAcquired 1 980grant · 2026-06-15
- Director · Stock Option (right to buy) → Common StockAcquired 3 772 @ $101,00grant · 2026-06-15
- Director · Deferred Stock Units → Common StockAcquired 1 980grant · 2026-06-15
- Director · Stock Option (right to buy) → Common StockAcquired 3 772 @ $101,00grant · 2026-06-15
- Director · Deferred Stock Units → Common StockAcquired 1 980grant · 2026-06-15
- Director · Stock Option (right to buy) → Common StockAcquired 3 772 @ $101,00grant · 2026-06-15
- Director · Deferred Stock Units → Common StockAcquired 1 980grant · 2026-06-15
- Director · Restricted Stock Units → Common StockAcquired 1 980grant · 2026-06-15
- CHIEF FINANCIAL OFFICER · Employee Stock Option (right to buy) → Common StockDisposed 2 393 @ $26,49exercise · 2026-06-09
- PRESIDENT AND COO · Stock Option (right to buy) → Common StockDisposed 16 988 @ $19,19exercise · 2026-06-05
- Director, CHIEF EXECUTIVE OFFICER · Employee Stock Option (right to buy) → Common StockDisposed 30 000 @ $2,94exercise · 2026-06-01
- Director · Restricted Stock Units → Common StockDisposed 3 977exercise · 2026-05-29
- Director · Restricted Stock Units → Common StockDisposed 3 977exercise · 2026-05-29
- Director · Restricted Stock Units → Common StockDisposed 3 977exercise · 2026-05-29
- Director · Restricted Stock Units → Common StockDisposed 3 977exercise · 2026-05-29
- Director · Stock Option (right to buy) → Common StockDisposed 2 000 @ $23,51exercise · 2026-05-15
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Net Cashcash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
- Capex To Revenuecapital_expenditure / revenue
- Return On Equitynet_income / total_equity
- Debt To Equity(short_term_debt + long_term_debt) / total_equity
- Cash Conversion Ratiooperating_cash_flow / net_income
- MIRM.O Market data — financials · 2026-05-28
- Mirum Pharmaceuticals Inc Market data — analyst estimates · 2026-05-28
Ownership & reference
Top holders
- Institutional Investor · as of 2026-03-310,31 %$627M
- Investment Managers · as of 2026-03-310,02 %$123M
- Investment Managers · as of 2026-03-310,02 %$0M
- Investment Managers · as of 2026-03-310,01 %$14M
- Institutional Investor · as of 2026-03-310,01 %$54M
- Institutional Investor · as of 2026-03-310,01 %$182M
- Investment Managers · as of 2026-03-310,01 %$67M
- Institutional Investor · as of 2026-03-310,01 %$26M
- Investment Managers · as of 2024-12-310,01 %$30M
- Investment Managers · as of 2026-03-310,01 %$61M
- Investment Managers · as of 2026-03-310,01 %$116M
- Brokerage Firms · as of 2026-03-310,01 %$21M
- Investment Managers · as of 2026-03-310,01 %$180M
- Investment Managers · as of 2026-03-310,01 %$39M
- Investment Managers · as of 2026-03-310,01 %$9M
- Investment Managers · as of 2026-03-310,00 %$36M
- Institutional Investor · as of 2026-03-310,00 %$20M
- Investment Managers · as of 2026-03-310,00 %$6M
- Investment Managers · as of 2025-12-310,00 %$205M
- Investment Managers · as of 2026-03-310,00 %$9M
- Investment Managers · as of 2026-03-310,00 %$5M
- Investment Managers · as of 2026-03-310,00 %$6M
- Investment Managers · as of 2026-03-310,00 %$3M
- Investment Managers · as of 2026-03-310,00 %$4M
- Funds · as of 2026-03-310,00 %$3M
- Brokerage Firms · as of 2026-03-310,00 %$2M
- Institutional Investor · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2024-06-300,00 %$3M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$0M
Insider activity
- CHIEF FINANCIAL OFFICER · Common StockSold 300 @ $124,94$37K · 2026-07-06
- CHIEF FINANCIAL OFFICER · Common StockSold 528 @ $123,84$65K · 2026-07-06
- CHIEF FINANCIAL OFFICER · Common StockSold 1 048 @ $122,43$128K · 2026-07-06
- CHIEF FINANCIAL OFFICER · Common StockSold 3 124 @ $121,67$380K · 2026-07-06
- Director, CHIEF EXECUTIVE OFFICER · Common StockSold 1 710 @ $124,79$213K · 2026-07-06
- Director, CHIEF EXECUTIVE OFFICER · Common StockSold 1 975 @ $123,74$244K · 2026-07-06
- Director, CHIEF EXECUTIVE OFFICER · Common StockSold 4 181 @ $122,34$512K · 2026-07-06
- Director, CHIEF EXECUTIVE OFFICER · Common StockSold 12 134 @ $121,65$1,5M · 2026-07-06
- Director, CHIEF EXECUTIVE OFFICER · Common StockOther 20 000 @ $2,94$59K · 2026-07-06
- SVP, GLOBAL CONTROLLER · Common StockSold 2 721 @ $120,00$327K · 2026-07-01
- SVP, GLOBAL CONTROLLER · Common StockSold 2 594 @ $101,95$264K · 2026-06-17
- CHIEF FINANCIAL OFFICER · Common StockOther 2 393 @ $26,49$63K · 2026-06-09
- CHIEF FINANCIAL OFFICER · Common StockSold 1 175 @ $93,95$110K · 2026-06-08
- CHIEF FINANCIAL OFFICER · Common StockSold 2 258 @ $92,84$210K · 2026-06-08
- CHIEF FINANCIAL OFFICER · Common StockSold 1 567 @ $95,12$149K · 2026-06-08
- PRESIDENT AND COO · Common StockOther 16 988 @ $19,19$326K · 2026-06-05
- Director, CHIEF EXECUTIVE OFFICER · Common StockSold 2 602 @ $94,64$246K · 2026-06-01
- Director · Common StockSold 3 977 @ $100,00$398K · 2026-06-01
- Director, CHIEF EXECUTIVE OFFICER · Common StockSold 16 595 @ $95,34$1,6M · 2026-06-01
- Director, CHIEF EXECUTIVE OFFICER · Common StockOther 30 000 @ $2,94$88K · 2026-06-01
- Director, CHIEF EXECUTIVE OFFICER · Common StockSold 1 973 @ $97,56$192K · 2026-06-01
- Director, CHIEF EXECUTIVE OFFICER · Common StockSold 1 021 @ $98,20$100K · 2026-06-01
- Director, CHIEF EXECUTIVE OFFICER · Common StockSold 883 @ $99,66$88K · 2026-06-01
- Director, CHIEF EXECUTIVE OFFICER · Common StockSold 6 926 @ $96,15$666K · 2026-06-01
- Director · Common StockOther 3 977 · 2026-05-29
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Total assets (YoY) (2025-12-31 vs 2024-12-31): 25.7%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): 440.7%Derived (calculated)
- Operating income (YoY) (2025-12-31 vs 2024-12-31): 74.7%Derived (calculated)
- Revenue (YoY) (2025-12-31 vs 2024-12-31): 54.7%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): 39.5%Derived (calculated)
- Total liabilities (YoY) (2025-12-31 vs 2024-12-31): 18.6%Derived (calculated)
- Net margin (FY 2025-12-31): -4.5%Derived (calculated)
- Return on equity (FY 2025-12-31): -7.4%Derived (calculated)
- Return on assets (FY 2025-12-31): -2.8%Derived (calculated)
- Current ratio (FY 2025-12-31): 2.67xDerived (calculated)
- Debt-to-equity (FY 2025-12-31): 1.68xDerived (calculated)
- Capex (YoY) (2025-12-31 vs 2024-12-31): -3.9%Derived (calculated)
- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): 33.3%Derived (calculated)
- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 74.6%Derived (calculated)
- EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 74.6%Derived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): 73.4%Derived (calculated)
- Current liabilities (annual): USD 205.8MSEC XBRL filing
- Total operating expenses (annual): USD 543.45MSEC XBRL filing
- Current assets (annual): USD 549.68MSEC XBRL filing
- Pre-tax income (annual): USD -21.43MSEC XBRL filing
- Shareholders' equity (annual): USD 314.69MSEC XBRL filing
- EPS (diluted) (annual): USD-PER-SHARES -0SEC XBRL filing
- Cash & equivalents (annual): USD 296.68MSEC XBRL filing
- Operating cash flow (annual): USD 55.83MSEC XBRL filing