OPKO Health Inc
OPKO Health Inc is a diversified healthcare company focused on the development, manufacturing, and commercialization of pharmaceutical products, primarily in the areas of women's health, endocrinology, and diagnostics.
Business. OPKO Health Inc (OPK.O) is a healthcare company operating within the Healthcare Facilities & Services industry, with activities focused on pharmaceuticals. The firm generates revenue through a service-based model and is headquartered in the United States. It is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.
Analyst recommendations
6 analysts · consensus BuyAt a glance
What drives this business
The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
News & coverage
0Sector rotation
Developing storylines
Analysis
AI analysisOpportunity
Upcoming catalysts
Scheduled public events. Informational only — not investment advice.
- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
OPKO Health Inc (OPK.O) is a healthcare company operating within the Healthcare Facilities & Services industry, with activities focused on pharmaceuticals. The firm generates revenue through a service-based model and is headquartered in the United States. It is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.
OPKO Health Inc has a liquidity position that appears stable, with a current ratio of 3.97, indicating the company can cover its short-term liabilities more than three times over. However, the company reported negative operating cash flow of -$178.54 million and free cash flow of -$146.30 million, suggesting ongoing cash burn despite holding $364.41 million in cash and equivalents.
Profitability metrics are weak, with a return on equity of -17.8% and a return on assets of -11.68%, both significantly below the industry median for healthcare firms. The company reported a net loss of $225.68 million and an operating loss of $209.11 million, indicating a challenging operating environment.
Geographically and segment-wise, OPKO Health Inc's revenue concentration is not disclosed in the available data. However, the company operates in a highly competitive and regulated industry, with exposure to pharmaceuticals, diagnostics, and healthcare services. The lack of segment-specific revenue breakdowns limits visibility into the performance of individual business lines.
Looking ahead, the company is expected to face continued financial pressure, with no clear signs of improvement in the near term. The operating loss and negative cash flows suggest a need for strategic adjustments or external financing to sustain operations. Analysts have assigned a mean price target of $3.78, with a median of $3.00, reflecting a cautious outlook.
Risk factors include liquidity constraints and the potential for dilution, although the risk of dilution is currently assessed as low. The company has not issued any recent warnings or flags related to liquidity or dilution, but the negative operating cash flow and free cash flow could signal underlying financial stress.
Recent events include the continued focus on cost management and operational efficiency, as well as the pursuit of strategic partnerships and product development. The company has not disclosed any major new product launches or regulatory approvals in the latest filings, but it remains active in the development of new therapies and diagnostic tools.
- OPKO Health Inc is experiencing significant financial losses, with a net loss of $225.68 million and an operating loss of $209.11 million.
- The company's liquidity position is stable, with a current ratio of 3.97, but it is burning cash at a rate of $178.54 million in operating cash flow.
- Profitability metrics are weak, with a return on equity of -17.8% and a return on assets of -11.68%.
- Analysts have a cautious outlook, with a mean price target of $3.78 and a median of $3.00.
- The company faces ongoing financial pressure and may need to pursue strategic adjustments or external financing to sustain operations.
Bull / Bear case
Generated · model-assistedIn focus — financials by report
Valuation
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -0,30 |
| Revenue | —no estimate | —no estimate | 534,9M USD |
| Operating income | —no estimate | —no estimate | -212,0M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Director · Stock Option (Right to Buy) → Common StockAcquired 30 000 @ $1,42grant · 2026-06-18
- Director · Stock Option (Right to Buy) → Common StockAcquired 30 000 @ $1,42grant · 2026-06-18
- Director · Stock Option (Right to Buy) → Common StockAcquired 80 000 @ $1,42grant · 2026-06-18
- Director · Stock Option (Right to Buy) → Common StockAcquired 30 000 @ $1,42grant · 2026-06-18
- Director · Stock Option (Right to Buy) → Common StockAcquired 30 000 @ $1,42grant · 2026-06-18
- Director · Stock Option (Right to Buy) → Common StockAcquired 60 000 @ $1,42grant · 2026-06-18
- Director · Stock Option (Right to Buy) → Common StockAcquired 50 000 @ $1,17grant · 2026-03-18
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Net Cashcash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
- Capex To Revenuecapital_expenditure / revenue
- Return On Equitynet_income / total_equity
- Debt To Equity(short_term_debt + long_term_debt) / total_equity
- Cash Conversion Ratiooperating_cash_flow / net_income
- OPKO Health Inc Market data — financials · 2026-05-28
- OPKO Health Inc Market data — analyst estimates · 2026-05-28
- OPKO Health Inc Market data — ESG · 2026-05-28
Ownership & reference
Top holders
- Investment Managers · as of 2026-03-310,00 %$7M
- Investment Managers · as of 2026-03-310,00 %$9M
- Investment Managers · as of 2024-06-300,00 %$37M
- Investment Managers · as of 2026-03-310,00 %$13M
- Investment Managers · as of 2026-03-310,00 %$4M
- Investment Managers · as of 2024-12-310,00 %$2M
- Investment Managers · as of 2025-12-310,00 %$41M
- Investment Managers · as of 2026-03-310,00 %$4M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$11M
- Investment Managers · as of 2026-03-310,00 %$2M
- Institutional Investor · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$1M
- Funds · as of 2026-03-310,00 %$1M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$0M
- Brokerage Firms · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Brokerage Firms · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
Leadership
- Phillip FrostChairman of the Board, Chief Executive Officer
Insider activity
- Director · Common StockBought 10 000 @ $1,14$11K · 2026-03-20
- Director, CEO & Chairman, 10% owner · Common StockBought 3 894 @ $1,32$5K · 2025-11-21
- Director, CEO & Chairman, 10% owner · Common StockBought 191 490 @ $1,33$255K · 2025-11-21
- Director, CEO & Chairman, 10% owner · Common StockBought 192 870 @ $1,33$257K · 2025-11-21
- Director, CEO & Chairman, 10% owner · Common StockBought 102 371 @ $1,30$133K · 2025-11-21
- Director, CEO & Chairman, 10% owner · Common StockBought 89 375 @ $1,32$118K · 2025-11-21
- Director, CEO & Chairman, 10% owner · Common StockBought 161 818 @ $1,33$216K · 2025-11-20
- Director, CEO & Chairman, 10% owner · Common StockBought 13 664 @ $1,35$18K · 2025-11-20
- Director, CEO & Chairman, 10% owner · Common StockBought 1 757 @ $1,34$2K · 2025-11-20
- Director, CEO & Chairman, 10% owner · Common StockBought 119 129 @ $1,32$157K · 2025-11-20
- Director, CEO & Chairman, 10% owner · Common StockBought 47 105 @ $1,32$62K · 2025-11-20
- Director, CEO & Chairman, 10% owner · Common StockBought 211 948 @ $1,33$282K · 2025-11-20
- Director, CEO & Chairman, 10% owner · Common StockBought 24 579 @ $1,34$33K · 2025-11-20
- Director, CEO & Chairman, 10% owner · Common StockBought 155 496 @ $1,32$205K · 2025-11-19
- Director, CEO & Chairman, 10% owner · Common StockBought 36 325 @ $1,28$46K · 2025-11-19
- Director, CEO & Chairman, 10% owner · Common StockBought 58 160 @ $1,28$75K · 2025-11-19
- Director, CEO & Chairman, 10% owner · Common StockBought 300 @ $1,29$387 · 2025-11-19
- Director, CEO & Chairman, 10% owner · Common StockBought 21 236 @ $1,29$28K · 2025-11-19
- Director, CEO & Chairman, 10% owner · Common StockBought 30 082 @ $1,30$39K · 2025-11-19
- Director, CEO & Chairman, 10% owner · Common StockBought 12 993 @ $1,30$17K · 2025-11-19
- Director, CEO & Chairman, 10% owner · Common StockBought 66 504 @ $1,31$87K · 2025-11-19
- Director, CEO & Chairman, 10% owner · Common StockBought 198 904 @ $1,31$262K · 2025-11-19
- Director, CEO & Chairman, 10% owner · Common StockBought 1 @ $1,29$1 · 2025-11-18
- Director, CEO & Chairman, 10% owner · Common StockBought 83 556 @ $1,28$107K · 2025-11-18
- Director, CEO & Chairman, 10% owner · Common StockBought 33 572 @ $1,29$43K · 2025-11-18
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Current ratio (FY 2025-12-31): 3.97xDerived (calculated)
- Net margin (FY 2025-12-31): -37,187.0%Derived (calculated)
- Gross margin (FY 2025-12-31): 33.9%Derived (calculated)
- Return on equity (FY 2025-12-31): -17,798.7%Derived (calculated)
- Return on assets (FY 2025-12-31): -11,681.5%Derived (calculated)
- Debt-to-equity (FY 2025-12-31): 0.52xDerived (calculated)
- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): -14.6%Derived (calculated)
- Cost of revenue (YoY) (2025-12-31 vs 2024-12-31): -18.9%Derived (calculated)
- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): -275.0%Derived (calculated)
- EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): -275.0%Derived (calculated)
- Gross profit (YoY) (2025-12-31 vs 2024-12-31): -5.8%Derived (calculated)
- Long-term debt (YoY) (2025-12-31 vs 2024-12-31): -21.3%Derived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): -324.0%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): 2.7%Derived (calculated)
- Operating income (YoY) (2025-12-31 vs 2024-12-31): 22.8%Derived (calculated)
- R&D expense (YoY) (2025-12-31 vs 2024-12-31): 17.9%Derived (calculated)
- Revenue (YoY) (2025-12-31 vs 2024-12-31): -14.9%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): -7.1%Derived (calculated)
- Total assets (YoY) (2025-12-31 vs 2024-12-31): -12.2%Derived (calculated)
- Total liabilities (YoY) (2025-12-31 vs 2024-12-31): -20.5%Derived (calculated)
- Cash & equivalents (annual): USD 364.41MSEC XBRL filing
- Cost of revenue (annual): USD 400.94MSEC XBRL filing
- Operating income (annual): USD -117.41MSEC XBRL filing
- Revenue (annual): USD 606.88MSEC XBRL filing