ProMIS Neurosciences Inc
ProMIS Neurosciences Inc is a clinical-stage biopharmaceutical company focused on the discovery and development of novel therapeutics for neurodegenerative diseases, primarily Alzheimer's disease.
Business. ProMIS Neurosciences Inc (PMN.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.
Analyst recommendations
4 analysts · consensus BuyAt a glance
What drives this business
The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
News & coverage
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Analysis
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Upcoming catalysts
Scheduled public events. Informational only — not investment advice.
- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
ProMIS Neurosciences Inc (PMN.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding operating segments and geographic revenue mix are not available.
ProMIS Neurosciences Inc operates with a highly leveraged equity structure, as evidenced by a price-to-book ratio of 1230.59 and a price-to-tangible-book ratio of 1230.59, indicating that the market capitalization significantly exceeds the book value of the company's tangible assets. The company has no long-term debt, and its debt-to-equity ratio is 0.0, suggesting a purely equity-funded capital structure. However, the company's liquidity position is rated as low, with a current ratio of 1.34, indicating that it has just enough current assets to cover its current liabilities.
The company's profitability is negative, with a return on equity of -47.15% and a return on assets of -1.02%, both of which are significantly below the industry median for biotechnology firms. The company reported a net loss of $3.64 million and an operating loss of $3.68 million in the latest period. These figures suggest that the company is not currently generating positive returns for its shareholders and is operating at a loss.
Geographically and segment-wise, the company's revenue concentration is not disclosed in the available data. However, as a clinical-stage biopharmaceutical company, its operations are likely concentrated in the United States, where the majority of its research and development activities are conducted. The company's business is heavily dependent on the success of its clinical trials and the eventual commercialization of its drug candidates.
The company's growth trajectory is speculative, as it is in the clinical development phase and has not yet commercialized any products. The outlook for the current fiscal year is not provided, but the company's operating cash flow of -$10.29 million and free cash flow of -$3.64 million indicate that it is not generating positive cash flows from operations. The company will need to secure additional financing to fund its operations and clinical trials, which could lead to further dilution of existing shareholders.
The risk assessment for the company indicates a low probability of immediate liquidity or dilution risks. However, the company's reliance on equity financing and the absence of long-term debt suggest that it may face dilution pressures in the future if it needs to raise additional capital to fund its operations. The company's dilution potential is currently rated as low, but this could change if the company's cash burn rate increases or if it fails to secure additional funding.
Recent events and filings do not indicate any immediate financial or operational risks for the company. The company has not issued any recent press releases or filed any 10-K or 10-Q reports that would suggest a material change in its financial condition or business strategy. However, the company's reliance on clinical trial outcomes and the regulatory approval process for its drug candidates introduces a high degree of uncertainty into its future prospects.
- ProMIS Neurosciences Inc is a clinical-stage biopharmaceutical company with no long-term debt and a highly leveraged equity structure.
- The company is currently operating at a loss, with a return on equity of -47.15% and a return on assets of -1.02%.
- The company's liquidity position is rated as low, with a current ratio of 1.34, indicating that it has just enough current assets to cover its current liabilities.
- The company's growth trajectory is speculative, as it is in the clinical development phase and has not yet commercialized any products.
- The company's risk assessment indicates a low probability of immediate liquidity or dilution risks, but its reliance on equity financing could lead to future dilution pressures.
Bull / Bear case
Generated · model-assistedIn focus — financials by report
Operating income −165,0% YoY; Net income −224,8% YoY.
- ▍Operating income −165,0% YoY
- ▍Net income −224,8% YoY
Operating income −275,3% YoY; Net income −285,6% YoY.
- ▍Operating income −275,3% YoY
- ▍Net income −285,6% YoY
Operating income −102,9% YoY; Net income −102,1% YoY.
- ▍Operating income −102,9% YoY
- ▍Net income −102,1% YoY
Operating income -$6.0M.
- ▍Operating income -$6.0M
Operating income -$4.4M.
- ▍Operating income -$4.4M
Operating income -$2.7M.
- ▍Operating income -$2.7M
Operating income -$3.7M.
- ▍Operating income -$3.7M
Operating income −18,0% YoY; Net income +121,0% YoY.
- ▍Operating income −18,0% YoY
- ▍Net income +121,0% YoY
- ▍Free cash flow +121,1% YoY
Operating income +35,4% YoY; Net income +26,9% YoY.
- ▍Operating income +35,4% YoY
- ▍Net income +26,9% YoY
- ▍Free cash flow +26,9% YoY
Valuation TTM
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -5,05 |
| Revenue | —no estimate | —no estimate | 0 USD |
| Operating income | —no estimate | —no estimate | -46,0M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Director · Option (right to buy) → Common SharesAcquired 11 000 @ $10,77grant · 2026-05-20
- Director · Option (right to buy) → Common SharesAcquired 5 500 @ $10,77grant · 2026-05-20
- Director · Option (right to buy) → Common SharesAcquired 5 500 @ $10,77grant · 2026-05-20
- Director · Option (right to buy) → Common SharesAcquired 11 000 @ $10,77grant · 2026-05-20
- Director, Chief Executive Officer · Option (right to buy) → Common SharesAcquired 160 000 @ $10,77grant · 2026-05-20
- Director · Option (right to buy) → Common SharesAcquired 5 500 @ $10,77grant · 2026-05-20
- Director · Option (right to buy) → Common SharesAcquired 5 500 @ $10,77grant · 2026-05-20
- Director · Option (right to buy) → Common SharesAcquired 11 000 @ $10,77grant · 2026-05-20
- Director, Chief Scientific Officer · Option (right to buy) → Common SharesAcquired 50 000 @ $10,77grant · 2026-05-20
- Director · Option (right to buy) → Common SharesAcquired 11 000 @ $10,77grant · 2026-05-20
- Director · Option (right to buy) → Common SharesAcquired 5 500 @ $10,77grant · 2026-05-20
- Chief Development Officer · Option (right to buy) → Common SharesAcquired 50 000 @ $10,77grant · 2026-05-20
- Director · Option (right to buy) → Common SharesAcquired 11 000 @ $10,77grant · 2026-05-20
- Principal Accounting Officer · Option (right to buy) → Common SharesAcquired 18 167 @ $10,77grant · 2026-05-20
- Director, Chief Scientific Officer · Warrants to purchase Common Shares → Common SharesAcquired 4 122 @ $14,40grant · 2026-02-03
- 10% owner · Warrants → Common SharesAcquired 700 741 @ $14,40purchase · 2026-02-03
- Director · Warrants to purchase Common Shares → Common SharesAcquired 3 050 @ $14,40grant · 2026-02-03
- Principal Accounting Officer · Warrants to purchase Common Shares → Common SharesAcquired 6 595 @ $14,40grant · 2026-02-03
- Director, Chief Executive Officer · Warrants to purchase Common Shares → Common SharesAcquired 6 183 @ $14,40grant · 2026-02-03
- Chief Development Officer · Warrants to purchase Common Shares → Common SharesAcquired 2 060 @ $14,40grant · 2026-02-03
- 10% owner · Option (right to buy) → Common SharesAcquired 40 000 @ $0,45grant · 2025-10-22
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Market Priceinput from market-data provider (delayed close or quote-shim mid)
- Market Capmarket_price * shares_outstanding_diluted
- Return On Equitynet_income / total_equity
- Price To Tangible Bookmarket_price / (tangible_book_value / shares_outstanding_diluted)
- Debt To Equity(short_term_debt + long_term_debt) / total_equity
- ProMIS Neurosciences Inc Market data — financials · 2026-05-29
- ProMIS Neurosciences Inc Market data — analyst estimates · 2026-05-29
Ownership & reference
Top holders
- Institutional Investor · as of 2026-03-310,01 %$16M
- Investment Managers · as of 2026-03-310,00 %$9M
- Investment Managers · as of 2026-03-310,00 %$0M
Leadership
- Eugene WilliamsExecutive Chairman of the Board
Insider activity
- Director · Common SharesBought 4 000 @ $11,33$45K · 2026-04-22
- Director · Common SharesBought 2 000 @ $24,40$49K · 2026-03-05
- Director · Common SharesBought 2 000 @ $24,00$48K · 2026-03-04
- Director · Common SharesBought 1 000 @ $21,89$22K · 2026-03-03
- Director · Common SharesBought 1 000 @ $22,53$23K · 2026-03-02
- Chief Development Officer · Common SharesBought 1 629 @ $15,35$25K · 2026-02-19
- Chief Development Officer · Common SharesOther 2 060 @ $12,13$25K · 2026-02-03
- Director, Chief Scientific Officer · Common SharesOther 4 122 @ $12,13$50K · 2026-02-03
- Director, Chief Executive Officer · Common SharesOther 6 183 @ $12,13$75K · 2026-02-03
- Principal Accounting Officer · Common SharesOther 6 595 @ $12,13$80K · 2026-02-03
- Director · Common SharesOther 3 050 @ $12,13$37K · 2026-02-03
- 10% owner · Common SharesBought 700 741 @ $12,13$8,5M · 2026-02-03
- Principal Accounting Officer · Common SharesBought 30 392 @ $0,49$15K · 2025-10-03
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Total assets (YoY) (2025-12-31 vs 2024-12-31): -51.4%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): -107.6%Derived (calculated)
- R&D expense (YoY) (2025-12-31 vs 2024-12-31): 213.8%Derived (calculated)
- Operating income (YoY) (2025-12-31 vs 2024-12-31): -138.7%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -3.4%Derived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): -1,529.3%Derived (calculated)
- EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): -959.7%Derived (calculated)
- Return on equity (FY 2025-12-31): 3,155.8%Derived (calculated)
- Return on assets (FY 2025-12-31): -432.6%Derived (calculated)
- Debt-to-equity (FY 2025-12-31): -8.30xDerived (calculated)
- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): -943.7%Derived (calculated)
- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): -54.0%Derived (calculated)
- Current ratio (FY 2025-12-31): 0.88xDerived (calculated)
- Total liabilities (YoY) (2025-12-31 vs 2024-12-31): 330.9%Derived (calculated)
- Current assets (annual): USD 9.18MSEC XBRL filing
- Shares outstanding (annual): 2.15MSEC XBRL filing
- EPS (basic) (annual): USD-PER-SHARES -23SEC XBRL filing
- Total operating expenses (annual): USD 40.17MSEC XBRL filing
- Net income (annual): USD -39.72MSEC XBRL filing
- Cash & equivalents (annual): USD 6.12MSEC XBRL filing
- Shareholders' equity (annual): USD -1.26MSEC XBRL filing
- Operating cash flow (annual): USD -28.12MSEC XBRL filing
- Total assets (annual): USD 9.18MSEC XBRL filing
- Total liabilities (annual): USD 10.44MSEC XBRL filing