Plus Therapeutics Inc

The company's capital structure is characterized by a negative equity position of $4.84 million and a debt-to-equity ratio of -0.74, indicating a leveraged position with liabilities exceeding assets. The liquidity position is further constrained by a current ratio of 0.41, suggesting limited short-term liquidity to cover immediate obligations. Despite holding $2.90 million in cash and equivalents, the company's operating cash flow of -$4.51 million and free cash flow of -$3.15 million indicate ongoing cash outflows from operations, which could pressure liquidity in the near term.

Profitability metrics show a challenging financial position, with a net loss of $3.26 million and an operating loss of $3.30 million. The return on equity of 67.42% is unusually high given the negative equity, and the return on assets of -5.80% reflects poor asset utilization. These figures are significantly below the industry median for biotechnology firms, which typically report positive returns on equity and assets during periods of growth and development.

Geographically, Plus Therapeutics Inc does not disclose segment-specific revenue data, but its operations are primarily focused on the development of its IL-2 product candidate. The company's revenue concentration is not explicitly detailed, but the absence of disclosed geographic or product segments suggests a high concentration risk in its single therapeutic area.

The company's growth trajectory is uncertain, with no disclosed revenue growth in the most recent period. The lack of positive revenue growth, combined with ongoing losses, suggests a need for significant investment to bring its product candidate to market. The company's capital expenditure of -$40,000 indicates minimal investment in physical assets, which is typical for a development-stage biotechnology firm.

Risk factors include a high liquidity risk due to negative working capital and a negative net cash position after subtracting total debt. The company's dilution risk is currently low, but the potential for future dilution exists if the company needs to raise additional capital to fund operations. The company's reliance on a single product candidate and the high costs associated with clinical trials and regulatory approval add to the overall risk profile.

Recent events include the continued development of its IL-2 product candidate, with no significant new product launches or regulatory approvals reported. The company's recent financial filings highlight the need for ongoing capital to support its development pipeline, and there are no recent transcripts from earnings calls or investor presentations that provide additional insight into the company's strategic direction.

Analysts project 871.9% upside to a mean price target of $38.00, signaling strong institutional confidence in future growth.

Return on equity of 0.67 ranks best-in-class compared to the biotechnology cohort median of -0.22.

Operating margin of -1.97% outperforms the cohort median of -2.56%, indicating relatively better cost management.

Long-term debt decreased significantly to $750,000 in FY2026, reducing leverage risks compared to prior years.

Cash conversion ratio of 1.38 exceeds the 75th percentile of the biotechnology cohort median of 0.87.

The company carries a high credit risk flag, suggesting potential difficulties in meeting financial obligations.

Leverage band is classified as high with a debt-to-equity ratio of 3.09, increasing financial vulnerability.

Revenue $1.4M, −3,2% YoY; Operating income −47,2% YoY.

• ▍Revenue $1.4M, −3,2% YoY
• ▍Operating income −47,2% YoY
• ▍Net income −46,4% YoY
• ▍Free cash flow −50,5% YoY
• ▍Net margin -417.9%

Revenue $1.4M, −4,0% YoY; Operating income −18,0% YoY.

• ▍Revenue $1.4M, −4,0% YoY
• ▍Operating income −18,0% YoY
• ▍Net income −53,9% YoY
• ▍Free cash flow −62,9% YoY
• ▍Net margin -316.6%

Revenue $1.4M, +8,7% YoY; Operating income +58,4% YoY.

• ▍Revenue $1.4M, +8,7% YoY
• ▍Operating income +58,4% YoY
• ▍Net income +275,2% YoY
• ▍Free cash flow +253,7% YoY
• ▍Net margin 370.6%

Revenue $1.1M, −36,9% YoY; Operating income −7,2% YoY.

• ▍Revenue $1.1M, −36,9% YoY
• ▍Operating income −7,2% YoY
• ▍Net income −433,6% YoY
• ▍Free cash flow −448,6% YoY
• ▍Net margin -1643.2%

Revenue $1.4M; Operating income -$3.9M.

• ▍Revenue $1.4M
• ▍Operating income -$3.9M
• ▍Net margin -276.4%

Revenue $1.5M; Operating income -$3.8M.

• ▍Revenue $1.5M
• ▍Operating income -$3.8M
• ▍Net margin -197.4%

Revenue $1.3M; Operating income -$3.7M.

• ▍Revenue $1.3M
• ▍Operating income -$3.7M
• ▍Net margin -229.9%

Revenue $1.7M; Operating income -$3.3M.

• ▍Revenue $1.7M
• ▍Operating income -$3.3M
• ▍Net margin -194.5%

Revenue $5.2M, −10,5% YoY; Operating income −4,1% YoY.

• ▍Revenue $5.2M, −10,5% YoY
• ▍Operating income −4,1% YoY
• ▍Net income −72,5% YoY
• ▍Free cash flow −70,8% YoY
• ▍Net margin -429.4%

Revenue $5.8M, +18,5% YoY; Operating income −10,3% YoY.

• ▍Revenue $5.8M, +18,5% YoY
• ▍Operating income −10,3% YoY
• ▍Net income +2,5% YoY
• ▍Free cash flow −1,5% YoY
• ▍Net margin -222.8%

Revenue $4.9M, +2 093,3% YoY; Operating income +32,4% YoY.

• ▍Revenue $4.9M, +2 093,3% YoY
• ▍Operating income +32,4% YoY
• ▍Net income +34,3% YoY
• ▍Free cash flow +36,6% YoY
• ▍Net margin -271.0%

Revenue $224.0k; Operating income −57,8% YoY.

• ▍Revenue $224.0k
• ▍Operating income −57,8% YoY
• ▍Net income −51,3% YoY
• ▍Free cash flow −53,4% YoY
• ▍Net margin -9051.3%