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INDICATIVE · SAMPLE DATA
PSTV$5.7659

Plus Therapeutics Inc

Biotechnology & Medical ResearchVerified

The company's capital structure is characterized by a negative equity position of $4.84 million and a debt-to-equity ratio of -0.74, indicating a leveraged position with liabilities exceeding assets. The liquidity position is further constrained by a current ratio of 0.41, suggesting limited short-term liquidity to cover immediate obligations. Despite holding $2.90 million in cash and equivalents, the company's operating cash flow of -$4.51 million and free cash flow of -$3.15 million indicate ongoing cash outflows from operations, which could pressure liquidity in the near term. Profitability metrics show a challenging financial position, with a net loss of $3.26 million and an operating loss of $3.30 million. The return on equity of 67.42% is unusually high given the negative equity, and the return on assets of -5.80% reflects poor asset utilization. These figures are significantly below the industry median for biotechnology firms, which typically report positive returns on equity and assets during periods of growth and development. Geographically, Plus Therapeutics Inc does not disclose segment-specific revenue data, but its operations are primarily focused on the development of its IL-2 product candidate. The company's revenue concentration is not explicitly detailed, but the absence of disclosed geographic or product segments suggests a high concentration risk in its single therapeutic area. The company's growth trajectory is uncertain, with no disclosed revenue growth in the most recent period. The lack of positive revenue growth, combined with ongoing losses, suggests a need for significant investment to bring its product candidate to market. The company's capital expenditure of -$40,000 indicates minimal investment in physical assets, which is typical for a development-stage biotechnology firm. Risk factors include a high liquidity risk due to negative working capital and a negative net cash position after subtracting total debt. The company's dilution risk is currently low, but the potential for future dilution exists if the company needs to raise additional capital to fund operations. The company's reliance on a single product candidate and the high costs associated with clinical trials and regulatory approval add to the overall risk profile. Recent events include the continued development of its IL-2 product candidate, with no significant new product launches or regulatory approvals reported. The company's recent financial filings highlight the need for ongoing capital to support its development pipeline, and there are no recent transcripts from earnings calls or investor presentations that provide additional insight into the company's strategic direction.

30-day price · PSTV+0.67 (+12.6%)
Low$2.90High$8.00Close$6.04As of12 May, 00:00 UTC
Profile
CompanyPlus Therapeutics Inc
TickerPSTV.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Plus Therapeutics Inc is a biotechnology company focused on the development of novel therapies for the treatment of cancer, primarily through its proprietary PEGylated recombinant interleukin-2 (IL-2) product candidate, which is designed to enhance the immune system's ability to target and destroy cancer cells.

Classification. Plus Therapeutics Inc is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

The company's capital structure is characterized by a negative equity position of $4.84 million and a debt-to-equity ratio of -0.74, indicating a leveraged position with liabilities exceeding assets. The liquidity position is further constrained by a current ratio of 0.41, suggesting limited short-term liquidity to cover immediate obligations. Despite holding $2.90 million in cash and equivalents, the company's operating cash flow of -$4.51 million and free cash flow of -$3.15 million indicate ongoing cash outflows from operations, which could pressure liquidity in the near term. Profitability metrics show a challenging financial position, with a net loss of $3.26 million and an operating loss of $3.30 million. The return on equity of 67.42% is unusually high given the negative equity, and the return on assets of -5.80% reflects poor asset utilization. These figures are significantly below the industry median for biotechnology firms, which typically report positive returns on equity and assets during periods of growth and development. Geographically, Plus Therapeutics Inc does not disclose segment-specific revenue data, but its operations are primarily focused on the development of its IL-2 product candidate. The company's revenue concentration is not explicitly detailed, but the absence of disclosed geographic or product segments suggests a high concentration risk in its single therapeutic area. The company's growth trajectory is uncertain, with no disclosed revenue growth in the most recent period. The lack of positive revenue growth, combined with ongoing losses, suggests a need for significant investment to bring its product candidate to market. The company's capital expenditure of -$40,000 indicates minimal investment in physical assets, which is typical for a development-stage biotechnology firm. Risk factors include a high liquidity risk due to negative working capital and a negative net cash position after subtracting total debt. The company's dilution risk is currently low, but the potential for future dilution exists if the company needs to raise additional capital to fund operations. The company's reliance on a single product candidate and the high costs associated with clinical trials and regulatory approval add to the overall risk profile. Recent events include the continued development of its IL-2 product candidate, with no significant new product launches or regulatory approvals reported. The company's recent financial filings highlight the need for ongoing capital to support its development pipeline, and there are no recent transcripts from earnings calls or investor presentations that provide additional insight into the company's strategic direction.
Key takeaways
  • Plus Therapeutics Inc is a development-stage biotechnology company with a negative equity position and ongoing operating losses.
  • The company's liquidity position is constrained by a current ratio of 0.41 and negative net cash after subtracting total debt.
  • Profitability metrics are poor, with a return on assets of -5.80% and a return on equity of 67.42%, which is misleading due to the negative equity.
  • The company's growth trajectory is uncertain, with no disclosed revenue growth and a high reliance on a single product candidate.
  • The company faces significant liquidity and dilution risks, with a need for ongoing capital to fund operations and development.
  • # RATIONALES
  • {
  • "margin_outlook_rationale": "The company's margin outlook is negative due to ongoing operating losses and a lack of positive revenue growth.",
Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$1.7M
Gross profit
Operating income-$3.3M
Net income-$3.3M
R&D
SG&A
D&A
SBC
Operating cash flow-$4.5M
CapEx-$40.0k
Free cash flow-$3.1M
Total assets$5.6M
Total liabilities$10.5M
Total equity-$4.8M
Cash & equivalents$2.9M
Long-term debt$3.6M
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY-4$0.00-$12.5M-$13.4M-$13.1M
FY-3$224.0k-$19.7M-$20.3M-$20.2M
FY-2$4.9M-$13.3M-$13.3M-$12.8M
FY-1$5.8M-$14.7M-$13.0M-$13.0M
FY0$5.2M-$15.3M-$22.4M-$22.2M
PeriodGross %Op %Net %FCF %
FY-4
FY-3
FY-2
FY-1
FY0
PeriodAssetsEquityCashDebt
FY-4$22.0M$10.8M$18.4M
FY-3$23.9M$6.4M$18.1M
FY-2$11.4M-$1.3M$8.6M
FY-1$6.6M-$8.9M$76.0k
FY0$16.3M$4.0M$4.3M
PeriodOCFCapExFCFSBC
FY-4-$10.3M-$144.0k-$13.1M
FY-3-$13.0M-$509.0k-$20.2M
FY-2-$12.9M-$160.0k-$12.8M
FY-1-$10.6M-$691.0k-$13.0M
FY0-$20.8M-$67.0k-$22.2M
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ-7$1.7M-$3.3M-$3.3M-$3.1M
FQ-6$1.3M-$3.7M-$2.9M-$3.4M
FQ-5$1.5M-$3.8M-$2.9M-$2.7M
FQ-4$1.4M-$3.9M-$3.9M-$3.7M
FQ-3$1.1M-$3.5M-$17.4M-$17.3M
FQ-2$1.4M-$1.5M$5.2M$5.2M
FQ-1$1.4M-$4.5M-$4.4M-$4.4M
FQ0$1.4M-$5.7M-$5.7M-$5.6M
PeriodGross %Op %Net %FCF %
FQ-7
FQ-6
FQ-5
FQ-4
FQ-3
FQ-2
FQ-1
FQ0
PeriodAssetsEquityCashDebt
FQ-7$5.6M-$4.8M$2.9M
FQ-6$11.2M-$7.6M$4.9M
FQ-5$7.0M-$5.2M$1.2M
FQ-4$6.6M-$8.9M$76.0k
FQ-3$12.1M-$23.6M$9.9M
FQ-2$10.3M$3.0M$2.2M
FQ-1$18.7M$5.1M$13.3M
FQ0$16.3M$4.0M$4.3M
PeriodOCFCapExFCFSBC
FQ-7-$4.5M-$40.0k-$3.1M
FQ-6-$5.7M-$666.0k-$3.4M
FQ-5-$9.3M-$680.0k-$2.7M
FQ-4-$10.6M-$691.0k-$3.7M
FQ-3-$6.2M-$3.0k-$17.3M
FQ-2-$12.0M-$10.0k$5.2M
FQ-1-$14.5M-$44.0k-$4.4M
FQ0-$20.8M-$67.0k-$5.6M
Valuation
Market price$5.76
Market cap$39.5M
Enterprise value$40.2M
P/E
Reported non-GAAP P/E
EV/Revenue24.0
EV/Op income
EV/OCF
P/B
P/Tangible book
Tangible book-$4.8M
Net cash-$689.0k
Current ratio0.4
Debt/Equity-0.7
ROA-58.0%
ROE67.4%
Cash conversion1.4%
CapEx/Revenue-2.4%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskMedium
  • Net cash is negative after subtracting total debt.
Industry benchmarks
Activity: Healthcare Diagnostics · cohort 170 companies
MetricPSTVActivity
Op margin-196.7%-227.5% medp25 -1250.6% · p75 -3.5%above median
Net margin-194.5%-194.5% medp25 -1233.8% · p75 0.8%above median
Gross margin53.0% medp25 25.9% · p75 75.7%
CapEx / revenue-2.4%-8.2% medp25 -35.2% · p75 -2.5%top quartile
Debt / equity-74.0%1.2% medp25 0.0% · p75 17.4%bottom quartile
Observations
IR observations
Mean price target38.00 USD
Median price target37.50 USD
High price target65.00 USD
Low price target12.00 USD
Mean recommendation2.20 (1=strong buy, 5=strong sell)
Strong-buy count0.00
Buy count4.00
Hold count1.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-3.56 USD
Last actual EPS-7.25 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-16 17:32 UTC#c41880ab
Market quoteclose USD 5.95 · shares 0.01B diluted
no public URL
2026-05-16 17:32 UTC#81c62286
Source: analysis-pipeline (hybrid)Generated: 2026-05-29 02:15 UTCJob: 918c9a2c