Pulse Biosciences Inc
Pulse Biosciences Inc is a clinical-stage biotechnology company focused on developing novel therapies for inflammatory and fibrotic diseases, generating no commercial revenue while incurring significant operating losses funded by cash reserves.
Business. Pulse Biosciences Inc is a clinical-stage biotechnology company focused on developing novel therapies for inflammatory and fibrotic diseases, generating no commercial revenue while incurring significant operating losses funded by cash reserves.
Analyst recommendations
3 analysts · consensus BuyAt a glance
What drives this business
The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
News & coverage
0Sector rotation
Developing storylines
Analysis
AI analysisOpportunity
Upcoming catalysts
Scheduled public events. Informational only — not investment advice.
- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
Pulse Biosciences Inc is a clinical-stage biotechnology company focused on developing novel therapies for inflammatory and fibrotic diseases, generating no commercial revenue while incurring significant operating losses funded by cash reserves.
Pulse Biosciences maintains a pristine balance sheet with $80.7 million in cash and equivalents against total liabilities of $13.9 million, resulting in a debt-to-equity ratio of 0.0. The company holds total assets of $94.5 million, with equity standing at $80.7 million. This strong liquidity position supports its ongoing operations despite the absence of commercial revenue. The current ratio is effectively infinite given the negligible liabilities relative to cash holdings, indicating no near-term solvency risk.
Profitability metrics are deeply negative, reflecting the company's pre-commercial status. Return on equity stands at -92.45%, and return on assets is -78.87%, driven by an operating income of -$76.9 million and net income of -$72.8 million. These figures are consistent with a biotechnology firm in the clinical development phase, where R&D and G&A expenses far exceed any revenue generation. The company generated only $350,000 in revenue, which is immaterial to the overall financial structure.
Revenue concentration is not applicable in the traditional sense as the company has no significant commercial segments. The $350,000 in revenue likely stems from minor licensing or collaboration activities, but no specific segment breakdown is provided. The geographic exposure is similarly undefined in the available data, though the company is listed on the Toronto Stock Exchange (PLSE.O), suggesting a primary operational base in North America.
Growth trajectory is characterized by a lack of top-line expansion, with revenue remaining negligible. The historical periods data is not provided, but the current financial snapshot indicates a static revenue base. The company's growth potential is tied to the clinical success of its pipeline rather than current sales trends. The operating cash flow of -$54.1 million highlights the cash burn rate associated with clinical trials and corporate overhead.
Risk assessment indicates low liquidity risk and low dilution risk. The key flags section notes no immediate filing-based liquidity or dilution flags. The primary risk is clinical execution risk, which is inherent to the biotechnology sector. The company's ability to raise additional capital if needed is supported by its strong cash position, but future dilution may occur if equity financing is required to fund later-stage trials.
Recent events include analyst coverage with a mean price target of $30.67 and a median target of $30.00. The mean recommendation is 1.67, indicating a strong buy consensus among the three analysts covering the stock. There are no recent filing or news observations provided, but the analyst sentiment suggests confidence in the company's clinical prospects.
- Strong liquidity position with $80.7 million in cash and zero debt.
- Deeply unprofitable with -92.45% ROE, typical for pre-revenue biotechs.
- Negligible revenue of $350,000 indicates no commercial operations.
- Low dilution and liquidity risk flags in the current assessment.
- Strong analyst consensus with a mean recommendation of 1.67.
- Cash burn rate of $54.1 million in operating cash flow requires monitoring.
Bull / Bear case
Generated · model-assistedThe company maintains zero long-term debt, resulting in a debt-to-equity ratio of 0.0, which significantly reduces financial leverage risk.
Analysts assign a mean price target of $30.67, implying a modest 1.2% upside from the current market price of $30.30.
Operating losses improved by 26.9% year-over-year, decreasing from $76.9 million to $56.3 million, indicating better cost management.
The firm holds a strong liquidity position with a current ratio of 10.53, suggesting ample short-term assets to cover liabilities.
Risk flags for both liquidity and dilution are rated as low, suggesting minimal immediate threats to capital structure stability.
The company recorded a net loss of $53.6 million, resulting in a net margin of -99.3%, which ranks in the bottom quartile.
Free cash flow burned $52.5 million, reflecting significant ongoing cash consumption without corresponding revenue generation to offset costs.
Operating margin of -103.9% is in the bottom quartile, indicating severe inefficiency in converting revenue into operating profit.
In focus — financials by report
Revenue $401.0k; Operating income −6,1% YoY.
- ▍Revenue $401.0k
- ▍Operating income −6,1% YoY
- ▍Net income −10,6% YoY
- ▍Free cash flow −10,9% YoY
- ▍Net margin -4633.7%
Revenue $264.0k; Operating income +9,9% YoY.
- ▍Revenue $264.0k
- ▍Operating income +9,9% YoY
- ▍Net income +10,1% YoY
- ▍Free cash flow +9,8% YoY
- ▍Net margin -6603.4%
Revenue $86.0k; Operating income −49,1% YoY.
- ▍Revenue $86.0k
- ▍Operating income −49,1% YoY
- ▍Net income −52,9% YoY
- ▍Free cash flow −54,4% YoY
- ▍Net margin -22540.7%
Revenue $0.00; Operating income −72,9% YoY.
- ▍Revenue $0.00
- ▍Operating income −72,9% YoY
- ▍Net income −68,4% YoY
- ▍Free cash flow −71,1% YoY
Revenue $350.0k; Operating income −36,8% YoY.
- ▍Revenue $350.0k
- ▍Operating income −36,8% YoY
- ▍Net income −35,8% YoY
- ▍Free cash flow −37,1% YoY
- ▍Net margin -20794.6%
Revenue $0.00, −100,0% YoY; Operating income +24,9% YoY.
- ▍Revenue $0.00, −100,0% YoY
- ▍Operating income +24,9% YoY
- ▍Net income +27,9% YoY
- ▍Free cash flow +28,5% YoY
Revenue $700.0k, −50,6% YoY; Operating income +7,9% YoY.
- ▍Revenue $700.0k, −50,6% YoY
- ▍Operating income +7,9% YoY
- ▍Net income +8,1% YoY
- ▍Free cash flow +8,6% YoY
- ▍Net margin -8357.9%
Revenue $1.4M; Operating income -$63.0M.
- ▍Revenue $1.4M
- ▍Operating income -$63.0M
- ▍Net margin -4489.4%
Valuation TTM
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -1,34 |
| Revenue | —no estimate | —no estimate | 2,6M USD |
| Operating income | —no estimate | —no estimate | -86,7M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Director · Stock Option (right to buy) → Common StockAcquired 30 000 @ $26,89grant · 2026-06-11
- Director, 10% owner · Stock Option (right to buy) → Common StockAcquired 30 000 @ $26,89grant · 2026-06-11
- Director · Stock Option (right to buy) → Common StockAcquired 8 423 @ $26,89grant · 2026-06-11
- Director · Stock Option (right to buy) → Common StockAcquired 30 000 @ $26,89grant · 2026-06-11
- Director · Stock Option (right to buy) → Common StockAcquired 14 504 @ $26,89grant · 2026-06-11
- Director · Stock Option (right to buy) → Common StockAcquired 30 000 @ $26,89grant · 2026-06-11
- Director, 10% owner · Stock Option (right to buy) → Common StockAcquired 12 495 @ $26,89grant · 2026-06-11
- Director · Stock Option (right to buy) → Common StockAcquired 30 000 @ $26,89grant · 2026-06-11
- Director · Stock Option (right to buy) → Common StockAcquired 3 793 @ $26,89grant · 2026-06-11
- Director, Chief Technology Officer · Restricted Stock Units → Common StockAcquired 100 000grant · 2026-03-23
- Chief Commercial Officer · Stock Option (right to buy) → Common StockDisposed 5 000 @ $1,53exercise · 2026-02-18
- Chief Commercial Officer · Stock Option (right to buy) → Common StockDisposed 20 000 @ $1,53exercise · 2026-02-17
- Chief Commercial Officer · Stock Option (right to buy) → Common StockDisposed 20 000 @ $1,53exercise · 2026-02-13
- Chief Commercial Officer · Stock Option (right to buy) → Common StockDisposed 20 000 @ $1,53exercise · 2026-02-12
- Chief Commercial Officer · Stock Option (right to buy) → Common StockDisposed 20 000 @ $1,53exercise · 2026-02-11
- Chief Commercial Officer · Stock Option (right to buy) → Common StockDisposed 20 000 @ $1,53exercise · 2026-02-10
- Chief Commercial Officer · Stock Option (right to buy) → Common StockDisposed 20 000 @ $1,53exercise · 2026-02-09
- Director · Stock Option (right to buy) → Common StockAcquired 3 104 @ $13,69grant · 2026-02-05
- Director · Stock Option (right to buy) → Common StockAcquired 50 000 @ $14,72grant · 2026-01-08
- Chief Commercial Officer · Stock Option (right to buy) → Common StockDisposed 4 600 @ $1,53exercise · 2025-10-02
- Chief Commercial Officer · Stock Option (right to buy) → Common StockDisposed 400 @ $1,53exercise · 2025-09-19
- Chief Commercial Officer · Stock Option (right to buy) → Common StockDisposed 20 000 @ $1,53exercise · 2025-09-18
- Director, Chief Technology Officer · Stock Option (right to buy) → Common StockDisposed 61 534 @ $4,00exercise · 2025-09-17
- Director, Chief Technology Officer · Stock Option (right to buy) → Common StockDisposed 20 000 @ $4,00exercise · 2025-09-17
- Director, Chief Technology Officer · Stock Option (right to buy) → Common StockDisposed 100 000 @ $4,00exercise · 2025-09-17
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Reference data
- Debt To Equity(short_term_debt + long_term_debt) / total_equity
- Cash Conversion Ratiooperating_cash_flow / net_income
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Net Cashcash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
- Return On Assetsnet_income / total_assets
- Return On Equitynet_income / total_equity
- Pulse Biosciences, Inc. Market data — financials · 2026-07-11
- Pulse Biosciences Inc Market data — analyst estimates · 2026-07-11
- Pulse Biosciences Inc Market data — ESG · 2026-07-11
Ownership & reference
Top holders
- Institutional Investor · as of 2026-03-310,00 %$10M
- Investment Managers · as of 2026-03-310,00 %$11M
- Investment Managers · as of 2026-03-310,00 %$4M
- Investment Managers · as of 2026-03-310,00 %$3M
- Investment Managers · as of 2026-03-310,00 %$10M
- Investment Managers · as of 2026-03-310,00 %$2M
- Investment Managers · as of 2024-06-300,00 %$13M
- Investment Managers · as of 2024-12-310,00 %$1M
- Investment Managers · as of 2025-12-310,00 %$15M
- Institutional Investor · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$1M
- Brokerage Firms · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
Leadership
- Bob William DugganExecutive Chairman of the Board
- Burke T. BarrettPresident, Chief Executive Officer, Director
- Kevin DanahyPresident, Chief Executive Officer
Insider activity
- Director, Chief Executive Officer · Common StockBought 15 000 @ $19,69$295K · 2026-05-11
- Director, 10% owner · Common StockBought 660 233 @ $19,69$13,0M · 2026-05-11
- Chief Commercial Officer · Common StockSold 5 000 @ $23,64$118K · 2026-02-18
- Chief Commercial Officer · Common StockOther 5 000 @ $1,53$8K · 2026-02-18
- Chief Commercial Officer · Common StockSold 20 000 @ $23,63$473K · 2026-02-17
- Chief Commercial Officer · Common StockOther 20 000 @ $1,53$31K · 2026-02-17
- Chief Commercial Officer · Common StockSold 20 000 @ $23,53$471K · 2026-02-13
- Chief Commercial Officer · Common StockOther 20 000 @ $1,53$31K · 2026-02-13
- Chief Commercial Officer · Common StockSold 20 000 @ $23,37$467K · 2026-02-12
- Chief Commercial Officer · Common StockOther 20 000 @ $1,53$31K · 2026-02-12
- Chief Commercial Officer · Common StockSold 20 000 @ $25,20$504K · 2026-02-11
- Chief Commercial Officer · Common StockOther 20 000 @ $1,53$31K · 2026-02-11
- Chief Commercial Officer · Common StockOther 20 000 @ $1,53$31K · 2026-02-10
- Chief Commercial Officer · Common StockSold 20 000 @ $23,52$470K · 2026-02-10
- Chief Commercial Officer · Common StockSold 20 000 @ $21,45$429K · 2026-02-09
- Chief Commercial Officer · Common StockOther 20 000 @ $1,53$31K · 2026-02-09
- Chief Commercial Officer · Common StockOther 4 600 @ $1,53$7K · 2025-10-02
- Chief Commercial Officer · Common StockSold 4 600 @ $18,53$85K · 2025-10-02
- Chief Commercial Officer · Common StockSold 400 @ $18,48$7K · 2025-09-19
- Chief Commercial Officer · Common StockOther 400 @ $1,53$612 · 2025-09-19
- Chief Commercial Officer · Common StockOther 20 000 @ $1,53$31K · 2025-09-18
- Chief Commercial Officer · Common StockSold 20 000 @ $18,49$370K · 2025-09-18
- Director, Chief Technology Officer · Common StockOther 100 000 @ $4,00$400K · 2025-09-17
- Director, Chief Technology Officer · Common StockOther 20 000 @ $4,00$80K · 2025-09-17
- Director, Chief Technology Officer · Common StockSold 20 000 @ $16,21$324K · 2025-09-17
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): -31.6%Derived (calculated)
- Net margin (FY 2025-12-31): -20,794.6%Derived (calculated)
- Return on equity (FY 2025-12-31): -90.2%Derived (calculated)
- Return on assets (FY 2025-12-31): -77.0%Derived (calculated)
- Current ratio (FY 2025-12-31): 10.53xDerived (calculated)
- Debt-to-equity (FY 2025-12-31): 0.17xDerived (calculated)
- Capex (YoY) (2025-12-31 vs 2024-12-31): 152.0%Derived (calculated)
- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): -17.4%Derived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): -35.8%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -48.9%Derived (calculated)
- Operating income (YoY) (2025-12-31 vs 2024-12-31): -36.8%Derived (calculated)
- R&D expense (YoY) (2025-12-31 vs 2024-12-31): 38.3%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): -29.8%Derived (calculated)
- Total assets (YoY) (2025-12-31 vs 2024-12-31): -28.6%Derived (calculated)
- Total liabilities (YoY) (2025-12-31 vs 2024-12-31): -21.1%Derived (calculated)
- Pre-tax income (annual): USD 72.8MSEC XBRL filing
- R&D expense (annual): USD 44.72MSEC XBRL filing
- EPS (basic) (annual): USD-PER-SHARES -1SEC XBRL filing
- Cost of revenue (annual): USD 539KSEC XBRL filing
- Capex (annual): USD 315KSEC XBRL filing
- Revenue (annual): USD 350KSEC XBRL filing
- Shares outstanding (annual): 67.84MSEC XBRL filing
- Cash & equivalents (annual): USD 80.73MSEC XBRL filing
- Shareholders' equity (annual): USD 80.66MSEC XBRL filing