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PYPD.O NASDAQ Pharmaceuticals

PolyPid Ltd

$4,48
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1D5D1M3M6MYTD1Y5YMax
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Mcap
85,5M USD
P/E
EV / Rev
Div yield
Op margin
ROE
-311,4 %
Net margin
Debt / equity
0,09
Beta
52w range
Volume
Day range
Prev close
$4,76
Open
$4,79
Next earnings
2026-10-28
Ex-dividend
TR 1Y
About

PolyPid Ltd is a clinical-stage biopharmaceutical company focused on the development of novel immunotherapies for the treatment of cancer, primarily through its lead product candidate, PEPvax, a personalized cancer vaccine platform.

Business. PolyPid Ltd (PYPD.O) is a pharmaceutical company operating within the Healthcare sector. The firm is headquartered in Israel and is primarily listed on the NASDAQ stock exchange. Specific details regarding its operating segments and geographic revenue mix are not available.

Classification92 %
SectorHealthcare
Business sectorPharmaceuticals & Medical Research
IndustryPharmaceuticals
Generated · model-assisted
Sell-side consensus
BUY4 analysts
4 buy0 hold0 sell
Avg 12m price target12,25

Analyst recommendations

4 analysts · consensus Buy
Buy4
Hold0
Sell0
12-month price target
12,25
Consensus of sell-side coverage.
Upcoming events
  • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
See all catalysts →

At a glance

Score
not yet scored
Valuation
valuation pending
Analysts
Buy
4 analysts · indicative
Ownership
Morgan Stanley Smith Barney LLC
largest disclosed fund holder
Profitability
-311,4 %
return on equity
Quality
not yet scored

What drives this business

The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.

— missing data

News & coverage

0
  • No recent newsroom coverage mentioning PYPD.
  • Sector rotation

    Sector1D1Mvs mkt
    Materials+2,3 %+6,6 %+1,7 %
    Communication Services+2,2 %−5,5 %+1,6 %
    Energy+0,6 %+3,3 %+0,0 %
    Health Care · THIS SECTOR+0,6 %−0,8 %+0,0 %
    Information Technology+0,6 %+6,7 %+0,0 %
    Consumer Discretionary+0,4 %+7,6 %−0,2 %
    Financials−0,3 %−2,8 %−0,9 %
    Consumer Staples−0,4 %+2,5 %−1,0 %
    Real Estate−0,7 %+10,9 %−1,3 %
    Industrials−1,9 %−3,1 %−2,5 %
    Utilities−1,9 %+28,2 %−2,5 %

    Developing storylines

    No tracked sagas currently linked to PYPD.O. Browse all sagas →

    Analysis

    AI analysis
    Generated · analysis pipeline · tier hybrid · as of 2026-08-04 ↑ At a glance

    Opportunity

    — missing data

    Upcoming catalysts

    Scheduled public events. Informational only — not investment advice.

    • Company
    • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
    • Macro
    • Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
    • Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
    • Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
    • Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
    • Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
    • Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
    • Macro & political
    • ElectionSE Swedish Election2026-09-14 · SE
    • ElectionUS U.S. Midterms2026-11-03 · US
    • ElectionFR French Legislative2027-06-01 · FR

    Pre-earnings brief

    — missing data

    Signals & dispatch

    peak dispatch · —

    Composite-score breakdown

    Synthesis

    Business

    PolyPid Ltd (PYPD.O) is a pharmaceutical company operating within the Healthcare sector. The firm is headquartered in Israel and is primarily listed on the NASDAQ stock exchange. Specific details regarding its operating segments and geographic revenue mix are not available.

    Classification92 %
    SectorHealthcare
    Business sectorPharmaceuticals & Medical Research
    IndustryPharmaceuticals
    AI synthesis
    GENERATED

    The company's capital structure is characterized by a high price-to-book ratio of 7.62, indicating that the market is valuing the company significantly above its book value. This is supported by a current ratio of 1.97, suggesting that the company has sufficient short-term assets to cover its short-term liabilities. However, the company's operating cash flow of -27.88 million USD and free cash flow of -32.92 million USD indicate a significant cash outflow from operations, which could be a concern for liquidity in the near term.

    In terms of profitability, PolyPid is currently unprofitable, with a net income of -34.17 million USD and an operating income of -33.48 million USD. The return on equity (ROE) is -3.11%, and the return on assets (ROA) is -1.53%, both of which are negative and significantly below the industry median for pharmaceutical companies. These metrics suggest that the company is not generating returns for its shareholders or effectively utilizing its assets to generate profit.

    The company's revenue is not disclosed in the provided data, and there is no information on its geographic exposure or segment performance. However, as a clinical-stage biopharmaceutical company, it is likely that the company's revenue is concentrated in a few key therapeutic areas or geographic regions, which could pose a concentration risk if those areas underperform or face regulatory challenges.

    The company's growth trajectory is uncertain, as it is currently unprofitable and has negative cash flows. The outlook for the current fiscal year and the next fiscal year is not provided in the data, but the company's reliance on external financing and its high price-to-book ratio suggest that it may be seeking growth through innovation and development rather than through immediate profitability. The company's capital expenditure of -210,000 USD indicates a small investment in long-term assets, which is typical for a company in the early stages of development.

    The risk assessment for PolyPid indicates a low level of liquidity risk and a low probability of dilution. However, the company's negative operating and free cash flows could pose a liquidity risk if it is unable to secure additional financing. The company's debt-to-equity ratio of 0.09 suggests that it is not heavily leveraged, which is a positive sign for financial stability. The absence of immediate filing-based liquidity or dilution flags is a positive indicator, but the company's financial performance and reliance on external financing could change this outlook if not managed effectively.

    Recent events related to PolyPid include the disclosure of its financial performance and the absence of immediate liquidity or dilution flags. The company's financial snapshot and valuation snapshot provide a clear picture of its current financial state, but there is no information on recent filings or transcripts that could provide additional insight into the company's strategic direction or operational performance.

    Key takeaways
    • PolyPid Ltd is a clinical-stage biopharmaceutical company with a focus on developing novel immunotherapies for cancer treatment.
    • The company is currently unprofitable, with negative operating and net income, and is experiencing significant cash outflows from operations.
    • The company's capital structure is characterized by a high price-to-book ratio and a low debt-to-equity ratio, indicating a market valuation significantly above book value and a low level of leverage.
    • The company's growth trajectory is uncertain, and it is likely relying on external financing to fund its operations and development activities.
    • The risk assessment indicates a low level of liquidity risk and a low probability of dilution, but the company's financial performance and reliance on external financing could change this outlook.

    Bull / Bear case

    Generated · model-assisted
    — missing data

    In focus — financials by report

    Valuation

    Market price
    $4,48
    Market cap
    $83.6M
    Enterprise value
    $78.2M
    P/E
    Non-GAAP P/E
    EV / Revenue
    EV / Op income
    EV / OCF
    P / B
    7.6x
    P / Tangible book
    7.6x
    Tangible book
    $11.0M
    Net cash
    $5.4M
    Current ratio
    2.0
    Debt / equity
    0.1
    ROA
    -1.5%
    ROE
    -3.1%
    Cash conversion
    82.0%
    CapEx / revenue
    SBC / revenue
    Dilution ratio
    0.0%

    Revenue by segment

    Market share

    — missing data

    Business relationships

    — missing data

    Supply chain

    — missing data

    Peer comparison

    — missing data

    Market position

    Stress test

    — missing data

    Predictor forecast

    Next quarternear-term
    Earnings · next quarterconf 45 %
    EPS
    Consensus EPS
    -1,47
    Predicted surprise
    +0,00
    Beat probability
    45 %
    Analysts
    4
    Other metrics
    Revenue
    no estimate
    Segment revenue
    no estimate
    Margin
    no estimate
    Segment margin
    no estimate
    as of 2026-05-16 · Earnings Surprise V1
    Period note: consensus is not fiscal-period-aligned at source — read as consensus vs the last reported actual, not a calibrated same-quarter surprise.
    Full fiscal year~1 year ahead
    Full fiscal year · our forecast vs guidance vs consensus
    MetricOur forecastGuidanceConsensus
    EPSno estimateno estimate-1,47
    Revenueno estimateno estimate0 USD
    Operating incomeno estimateno estimate-33,3M USD
    Full-year consensus mean (period as reported by source) · consensus in USD. Company-level full-year forecast and management guidance are not yet modelled at scale — shown as "no estimate", never inferred.
    Probabilistic model output — not investment advice. · generated 2026-08-04

    Options

    — missing data

    Short squeeze

    — missing data

    Earnings-call key lines

    — missing data

    Consensus distribution

    sell-side coverage
    Recommendation distribution4 analysts
    Strong buy0
    Buy4
    Hold0
    Sell0
    Strong sell0
    12-month price target$12,25 · Median $13,00
    Low $9,00High $14,00
    Operating income · consensus-33,3M USD
    EPS surprise
    −41,7 %
    reported vs consensus · miss

    Estimate revisions

    consensus EPS · 26-week trend
    — missing data

    Sell-side observations

    Low$9,00
    Mean$12,25
    Median$13,00
    High$14,00
    Spot$4,48
    +173.4 %implied to mean12-month sell-side price targets · ▲ spot

    Themes

    — missing data

    ESG

    — missing data

    Risk factors

    Dilution riskLow
    Liquidity riskLow
    Filing-based flags
    • No immediate filing-based liquidity or dilution flags were detected.

    Benchmarks vs cohort

    ROE-311,4 %Bottom quartile
    D/E0,09Above median
    Cash Conv0,82Below median

    Corporate actions / M&A

    — missing data

    FX exposure

    — missing data

    Comparable transactions

    — missing data

    Derivatives & instruments

    — missing data

    Actions

    Ask Handelsavisen

    — missing data
    Data sources
    • Market data
    • Market data cache
    • Issuer disclosures
    • Public news
    • Earnings transcripts
    • Consensus estimates
    • ESG data
    How metrics are computed
    • Return On Equity
      net_income / total_equity
    • Price To Book
      market_price / (adjusted_book_value / shares_outstanding_diluted)
    • Dilution Ratio
      (shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
    • Market Price
      input from market-data provider (delayed close or quote-shim mid)
    • Market Cap
      market_price * shares_outstanding_diluted
    • Net Cash
      cash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
    Source documents
    • PolyPid Ltd Market data — financials · 2026-05-29
    • PolyPid Ltd Market data — analyst estimates · 2026-05-29

    Ownership & reference

    Top holders

    • Morgan Stanley Smith Barney LLCInvestment Managers · as of 2026-03-310,00 %$1M

    Insider activity

    — missing data

    Short positioning

    283.2Kshares short+235.2% vs prior
    1.11days to cover
    28.1%short of daily vol
    26fails-to-deliver
    as of 2026-07-15 · short-interest report (free)

    Geographic breakdown

    — missing data
    Listings · one canonical issuer all listings resolve to the canonical
    PYPD.OCanonical
    NASDAQ · USD

    Intel & risk

    PredictorBeat prob45 %Surprise+0,00Full forecast →
    peak dispatch · —
    OSINT findings
    Dilution riskLow
    Liquidity riskLow
    No immediate filing-based liquidity or dilution flags were detected.

    Evidence & claims

    From filings & derived data
    • Return on assets (FY 2025-12-31): -153.2%Derived (calculated)
    • Current ratio (FY 2025-12-31): 1.97xDerived (calculated)
    • R&D expense (YoY) (2025-12-31 vs 2024-12-31): 4.4%Derived (calculated)
    • Net income (YoY) (2025-12-31 vs 2024-12-31): -17.7%Derived (calculated)
    • EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): -57.4%Derived (calculated)
    • Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): 42.8%Derived (calculated)
    • Total assets (YoY) (2025-12-31 vs 2024-12-31): -11.6%Derived (calculated)
    • EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): -57.4%Derived (calculated)
    • Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): -59.1%Derived (calculated)
    • Capex (YoY) (2025-12-31 vs 2024-12-31): 176.3%Derived (calculated)
    • Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -26.9%Derived (calculated)
    • Operating income (YoY) (2025-12-31 vs 2024-12-31): -17.6%Derived (calculated)
    • Return on equity (FY 2025-12-31): -311.4%Derived (calculated)
    • Capex (annual): USD 210KSEC XBRL filing
    • Operating income (annual): USD -32.97MSEC XBRL filing
    • Cash & equivalents (annual): USD 6.4MSEC XBRL filing
    • EPS (basic) (annual): USD-PER-SHARES 2SEC XBRL filing
    • R&D expense (annual): USD 23.81MSEC XBRL filing
    • Net income (annual): USD -34.17MSEC XBRL filing
    • Shareholders' equity (annual): USD 10.97MSEC XBRL filing
    • Operating cash flow (annual): USD -27.88MSEC XBRL filing
    • Shares outstanding (annual): 18.2MSEC XBRL filing
    • Current assets (annual): USD 15.23MSEC XBRL filing
    • Current liabilities (annual): USD 7.74MSEC XBRL filing
    Showing 24 of 60 surfaced claims.
    Atomic claims from regulatory filings and derived calculations. Provenance shown as source kind only.

    The Thread

    Everything we know, in order
    2026-10-28EVENTUpcomingQ3 2026 earnings (expected) estimated date
    2026-06-30 03:38 UTCEARNINGSUpcomingForecast: earnings_forecast (90d)
    2026-02-25FILINGANNUAL REPORT →
    The entity's full life in the product — typed, chronological, joined across Newspaper, Platform and Data. Our memory, made visible.
    Sources filings · IR · transcripts · market data · tier hybrid · as of 2026-08-04 Market data · Issuer disclosures · Public news · Earnings transcripts · Consensus estimates · ESG data Premium coverage