PolyPid Ltd
PolyPid Ltd is a clinical-stage biopharmaceutical company focused on the development of novel immunotherapies for the treatment of cancer, primarily through its lead product candidate, PEPvax, a personalized cancer vaccine platform.
Business. PolyPid Ltd (PYPD.O) is a pharmaceutical company operating within the Healthcare sector. The firm is headquartered in Israel and is primarily listed on the NASDAQ stock exchange. Specific details regarding its operating segments and geographic revenue mix are not available.
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4 analysts · consensus BuyAt a glance
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- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
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Composite-score breakdown
Synthesis
PolyPid Ltd (PYPD.O) is a pharmaceutical company operating within the Healthcare sector. The firm is headquartered in Israel and is primarily listed on the NASDAQ stock exchange. Specific details regarding its operating segments and geographic revenue mix are not available.
The company's capital structure is characterized by a high price-to-book ratio of 7.62, indicating that the market is valuing the company significantly above its book value. This is supported by a current ratio of 1.97, suggesting that the company has sufficient short-term assets to cover its short-term liabilities. However, the company's operating cash flow of -27.88 million USD and free cash flow of -32.92 million USD indicate a significant cash outflow from operations, which could be a concern for liquidity in the near term.
In terms of profitability, PolyPid is currently unprofitable, with a net income of -34.17 million USD and an operating income of -33.48 million USD. The return on equity (ROE) is -3.11%, and the return on assets (ROA) is -1.53%, both of which are negative and significantly below the industry median for pharmaceutical companies. These metrics suggest that the company is not generating returns for its shareholders or effectively utilizing its assets to generate profit.
The company's revenue is not disclosed in the provided data, and there is no information on its geographic exposure or segment performance. However, as a clinical-stage biopharmaceutical company, it is likely that the company's revenue is concentrated in a few key therapeutic areas or geographic regions, which could pose a concentration risk if those areas underperform or face regulatory challenges.
The company's growth trajectory is uncertain, as it is currently unprofitable and has negative cash flows. The outlook for the current fiscal year and the next fiscal year is not provided in the data, but the company's reliance on external financing and its high price-to-book ratio suggest that it may be seeking growth through innovation and development rather than through immediate profitability. The company's capital expenditure of -210,000 USD indicates a small investment in long-term assets, which is typical for a company in the early stages of development.
The risk assessment for PolyPid indicates a low level of liquidity risk and a low probability of dilution. However, the company's negative operating and free cash flows could pose a liquidity risk if it is unable to secure additional financing. The company's debt-to-equity ratio of 0.09 suggests that it is not heavily leveraged, which is a positive sign for financial stability. The absence of immediate filing-based liquidity or dilution flags is a positive indicator, but the company's financial performance and reliance on external financing could change this outlook if not managed effectively.
Recent events related to PolyPid include the disclosure of its financial performance and the absence of immediate liquidity or dilution flags. The company's financial snapshot and valuation snapshot provide a clear picture of its current financial state, but there is no information on recent filings or transcripts that could provide additional insight into the company's strategic direction or operational performance.
- PolyPid Ltd is a clinical-stage biopharmaceutical company with a focus on developing novel immunotherapies for cancer treatment.
- The company is currently unprofitable, with negative operating and net income, and is experiencing significant cash outflows from operations.
- The company's capital structure is characterized by a high price-to-book ratio and a low debt-to-equity ratio, indicating a market valuation significantly above book value and a low level of leverage.
- The company's growth trajectory is uncertain, and it is likely relying on external financing to fund its operations and development activities.
- The risk assessment indicates a low level of liquidity risk and a low probability of dilution, but the company's financial performance and reliance on external financing could change this outlook.
Bull / Bear case
Generated · model-assistedIn focus — financials by report
Valuation
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -1,47 |
| Revenue | —no estimate | —no estimate | 0 USD |
| Operating income | —no estimate | —no estimate | -33,3M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
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- Return On Equitynet_income / total_equity
- Price To Bookmarket_price / (adjusted_book_value / shares_outstanding_diluted)
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Market Priceinput from market-data provider (delayed close or quote-shim mid)
- Market Capmarket_price * shares_outstanding_diluted
- Net Cashcash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
- PolyPid Ltd Market data — financials · 2026-05-29
- PolyPid Ltd Market data — analyst estimates · 2026-05-29
Ownership & reference
Top holders
- Investment Managers · as of 2026-03-310,00 %$1M
Insider activity
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Return on assets (FY 2025-12-31): -153.2%Derived (calculated)
- Current ratio (FY 2025-12-31): 1.97xDerived (calculated)
- R&D expense (YoY) (2025-12-31 vs 2024-12-31): 4.4%Derived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): -17.7%Derived (calculated)
- EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): -57.4%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): 42.8%Derived (calculated)
- Total assets (YoY) (2025-12-31 vs 2024-12-31): -11.6%Derived (calculated)
- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): -57.4%Derived (calculated)
- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): -59.1%Derived (calculated)
- Capex (YoY) (2025-12-31 vs 2024-12-31): 176.3%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -26.9%Derived (calculated)
- Operating income (YoY) (2025-12-31 vs 2024-12-31): -17.6%Derived (calculated)
- Return on equity (FY 2025-12-31): -311.4%Derived (calculated)
- Capex (annual): USD 210KSEC XBRL filing
- Operating income (annual): USD -32.97MSEC XBRL filing
- Cash & equivalents (annual): USD 6.4MSEC XBRL filing
- EPS (basic) (annual): USD-PER-SHARES 2SEC XBRL filing
- R&D expense (annual): USD 23.81MSEC XBRL filing
- Net income (annual): USD -34.17MSEC XBRL filing
- Shareholders' equity (annual): USD 10.97MSEC XBRL filing
- Operating cash flow (annual): USD -27.88MSEC XBRL filing
- Shares outstanding (annual): 18.2MSEC XBRL filing
- Current assets (annual): USD 15.23MSEC XBRL filing
- Current liabilities (annual): USD 7.74MSEC XBRL filing