Handelsavisen
prelaunch
Companies Healthcare PYXS.O
PY
PYXS.O NASDAQ Pharmaceuticals & Medical Research

Pyxis Oncology Inc

$2,99
Open in Charts → Attach watcher ⌖
USD
Set alert
Last 30 days
1D5D1M3M6MYTD1Y5YMax
Live price chart loads from the market-data widget.
Mcap
188,0M USD
P/E
EV / Rev
Div yield
Op margin
-609,2 %
ROE
-149,1 %
Net margin
-574,5 %
Debt / equity
0,00
Beta
52w range
Volume
Day range
Prev close
$1,78
Open
$1,73
Next earnings
2026-10-28
Ex-dividend
TR 1Y
About

Pyxis Oncology Inc is a biotechnology company focused on the development of novel therapeutics for the treatment of cancer, primarily through its pipeline of small molecule drug candidates.

Business. Pyxis Oncology Inc (PYXS.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding its operating segments and geographic revenue mix are not available.

Classification99 %
SectorHealth Care
Industry groupPharmaceuticals & Medical Research
Generated · model-assisted
Sell-side consensus
BUY9 analysts
8 buy1 hold0 sell
Avg 12m price target6,88

Analyst recommendations

9 analysts · consensus Buy
Buy8
Hold1
Sell0
12-month price target
6,88
Consensus of sell-side coverage.
Upcoming events
  • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
See all catalysts →

At a glance

Score
not yet scored
Valuation
valuation pending
Analysts
Buy
9 analysts · indicative
Ownership
BlackRock Institutional Trust Company, N.A.
largest disclosed fund holder
Profitability
-149,1 %
return on equity
Quality
not yet scored

What drives this business

The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.

— missing data

News & coverage

0
  • No recent newsroom coverage mentioning PYXS.
  • Sector rotation

    Sector1D1Mvs mkt
    Materials+2,3 %+6,6 %+1,7 %
    Communication Services+2,2 %−5,5 %+1,6 %
    Energy+0,6 %+3,3 %+0,0 %
    Health Care · THIS SECTOR+0,6 %−0,8 %+0,0 %
    Information Technology+0,6 %+6,7 %+0,0 %
    Consumer Discretionary+0,4 %+7,6 %−0,2 %
    Financials−0,3 %−2,8 %−0,9 %
    Consumer Staples−0,4 %+2,5 %−1,0 %
    Real Estate−0,7 %+10,9 %−1,3 %
    Industrials−1,9 %−3,1 %−2,5 %
    Utilities−1,9 %+28,2 %−2,5 %

    Developing storylines

    No tracked sagas currently linked to PYXS.O. Browse all sagas →

    Analysis

    AI analysis
    Generated · analysis pipeline · tier hybrid · as of 2026-08-04 ↑ At a glance

    Opportunity

    — missing data

    Upcoming catalysts

    Scheduled public events. Informational only — not investment advice.

    • Company
    • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
    • Macro
    • Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
    • Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
    • Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
    • Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
    • Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
    • Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
    • Macro & political
    • ElectionSE Swedish Election2026-09-14 · SE
    • ElectionUS U.S. Midterms2026-11-03 · US
    • ElectionFR French Legislative2027-06-01 · FR

    Pre-earnings brief

    — missing data

    Signals & dispatch

    peak dispatch · —

    Composite-score breakdown

    Synthesis

    Business

    Pyxis Oncology Inc (PYXS.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding its operating segments and geographic revenue mix are not available.

    Classification99 %
    SectorHealth Care
    Industry groupPharmaceuticals & Medical Research
    AI synthesis
    GENERATED

    Pyxis Oncology Inc has a market capitalization of $142.05 million and a price-to-book ratio of 2.66, indicating that the market values the company at a premium to its book value. The company's liquidity position is characterized as medium, with a current ratio of 3.41, suggesting it has sufficient short-term assets to cover its short-term liabilities. However, the company has a negative net cash position after subtracting total debt, which could pose a liquidity risk.

    The company's profitability is currently negative, with a net loss of $79.62 million and an operating loss of $84.42 million. Its return on equity is -1.49, and return on assets is -0.87, both significantly below the typical performance metrics for the biotechnology industry. The company's gross profit margin is 82.8%, which is relatively high, but this is offset by substantial operating expenses.

    Pyxis Oncology Inc does not disclose specific revenue segments or geographic breakdowns in the provided data. However, the company's operations are likely concentrated in the United States, as is common for biotechnology firms. The lack of detailed segment reporting limits the ability to assess geographic or product diversification.

    The company's growth trajectory is uncertain, with no specific revenue growth rates provided. The company is in a development stage, and its future growth will depend on the success of its drug candidates in clinical trials and eventual commercialization. The company's capital expenditures are minimal, with only $9,000 spent in the latest period, indicating a focus on research and development rather than physical expansion.

    The company faces several risk factors, including its negative net cash position and the inherent risks associated with drug development, such as clinical trial failures and regulatory hurdles. The risk of dilution is currently low, as the number of shares outstanding has not changed between basic and diluted shares. However, the company may need to raise additional capital, which could lead to future dilution.

    Recent events include the publication of financial results and analyst estimates. Analysts have provided a mean price target of $6.88, with a median of $7.00, indicating a generally positive outlook despite the company's current financial challenges. The company has received a strong-buy recommendation from five analysts, suggesting that the market sees potential for future growth.

    Key takeaways
    • Pyxis Oncology Inc is a biotechnology company with a focus on developing novel cancer therapeutics.
    • The company is currently unprofitable, with significant net and operating losses.
    • The company's liquidity position is medium, with a current ratio of 3.41, but it has a negative net cash position.
    • Analysts have a generally positive outlook, with a mean price target of $6.88 and five strong-buy recommendations.
    • The company's future growth is contingent on the success of its drug candidates in clinical trials and regulatory approvals.

    Bull / Bear case

    Generated · model-assisted
    — missing data

    In focus — financials by report

    Valuation

    Market price
    $2,99
    Market cap
    $142.1M
    Enterprise value
    $142.1M
    P/E
    Non-GAAP P/E
    EV / Revenue
    EV / Op income
    EV / OCF
    P / B
    2.7x
    P / Tangible book
    2.7x
    Tangible book
    $53.4M
    Net cash
    -$23.0k
    Current ratio
    3.4
    Debt / equity
    0.0
    ROA
    -87.0%
    ROE
    -1.5%
    Cash conversion
    80.0%
    CapEx / revenue
    -0.1%
    SBC / revenue
    Dilution ratio
    0.0%

    Revenue by segment

    Market share

    INDUSTRYSEGMENTCOMPANYHealthcareIndustryPharmaceuticals & Medical Research15,2B node revenueKLAR 23,0%BNTX 21,4%EXEL 15,2%MDGL 6,3%INSM 4,0%VCYT 3,4%MDXG 2,8%AVIR 2,3%Other 21,6%
    Source: company disclosures · own-taxonomy revenue-covered setPYXS 0,1% · rank #49 of 109

    Business relationships

    Business relationships1 disclosed relationship · 1 type · extracted from filings & disclosures
    Partners1
    Pfizer IncPFE.TOPartner95%Source ↗

    Supply chain

    Vendors → PYXS ↔ Partners → Customers · click any node to drill
    VENDORSPARTNERSCUSTOMERSPYXSPYXSPyxis Oncology Inc1 entityPfizer IncPharmaceuticalsCA
    1 mention in 10-K0 from corporate websites0 from news dispatches
    Updated 2026-06-24

    Peer comparison

    Peer comparison8 peers · vs PYXS · multiples and returns
    KL
    KLAR
    KLAR.ST
    P/E
    vs self
    Div yield
    vs self
    ROE
    vs self
    BN
    BNTX
    Biontech SE
    $92,25
    23,3B USD
    P/E
    vs self
    Div yield
    vs self
    ROE
    vs self
    EX
    EXEL
    Exelixis Inc
    $55,06
    14,7B USD
    P/E
    19,5x
    vs self
    Div yield
    vs self
    ROE
    40,4 %
    +189,5 vs self
    MD
    MDGL
    Madrigal Pharmaceuticals Inc
    $482,00
    11,0B USD
    P/E
    vs self
    Div yield
    vs self
    ROE
    -47,8 %
    +101,2 vs self
    IN
    INSM
    Insmed Inc
    $107,46
    23,0B USD
    P/E
    vs self
    Div yield
    vs self
    ROE
    -160,2 %
    -11,1 vs self
    VC
    VCYT
    Veracyte Inc
    $45,30
    3,6B USD
    P/E
    55,5x
    vs self
    Div yield
    vs self
    ROE
    5,1 %
    +154,1 vs self
    MD
    MDXG
    Mimedx Group Inc
    $4,27
    636,0M USD
    P/E
    11,1x
    vs self
    Div yield
    vs self
    ROE
    18,9 %
    +168,0 vs self
    AV
    AVIR
    Atea Pharmaceuticals Inc
    $4,61
    P/E
    vs self
    Div yield
    vs self
    ROE
    -57,5 %
    +91,6 vs self

    Market position

    Stress test

    — missing data

    Predictor forecast

    Next quarternear-term
    Earnings · next quarterconf 45 %
    EPS
    Consensus EPS
    -1,29
    Predicted surprise
    +0,00
    Beat probability
    45 %
    Analysts
    9
    Other metrics
    Revenue
    no estimate
    Segment revenue
    no estimate
    Margin
    no estimate
    Segment margin
    no estimate
    as of 2026-05-10 · Earnings Surprise V1
    Period note: consensus is not fiscal-period-aligned at source — read as consensus vs the last reported actual, not a calibrated same-quarter surprise.
    Full fiscal year~1 year ahead
    Full fiscal year · our forecast vs guidance vs consensus
    MetricOur forecastGuidanceConsensus
    EPSno estimateno estimate-1,29
    Revenueno estimateno estimate43,750 USD
    Operating incomeno estimateno estimate-100,0M USD
    Full-year consensus mean (period as reported by source) · consensus in USD. Company-level full-year forecast and management guidance are not yet modelled at scale — shown as "no estimate", never inferred.
    Probabilistic model output — not investment advice. · generated 2026-08-04

    Options

    — missing data

    Short squeeze

    — missing data

    Earnings-call key lines

    — missing data

    Consensus distribution

    sell-side coverage
    Recommendation distribution9 analysts
    Strong buy5
    Buy3
    Hold1
    Sell0
    Strong sell0
    12-month price target$6,88 · Median $7,00
    Low $5,00High $9,00
    Operating income · consensus-100,0M USD
    EPS surprise
    +1,2 %
    reported vs consensus · beat
    Revenue surprise
    +31 575,4 %
    reported vs consensus · beat

    Estimate revisions

    consensus EPS · 26-week trend
    — missing data

    Sell-side observations

    Low$5,00
    Mean$6,88
    Median$7,00
    High$9,00
    Spot$2,99
    +129.8 %implied to mean12-month sell-side price targets · ▲ spot

    Themes

    — missing data

    ESG

    — missing data

    Risk factors

    Dilution riskLow
    Liquidity riskMedium
    Filing-based flags
    • Net cash is negative after subtracting total debt.

    Benchmarks vs cohort

    Op Margin-609,2 %Below median
    Net Margin-574,5 %Below median
    ROE-149,1 %Bottom quartile
    Capex / Rev-0,1 %Above P75
    D/E0,00Above median
    Cash Conv0,80Below median

    Corporate actions / M&A

    — missing data

    FX exposure

    — missing data

    Comparable transactions

    — missing data

    Derivatives & instruments

    Derivative transactions

    Net acquired 1 273 835 sh9 grants9 insiders
    • Cline Darren SDirector · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
    • Dupont JakobDirector · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
    • Wadhane JitendraPrin Fin & Acct Officer · Stock Option (Right to Buy) → Common StockAcquired 262 635 @ $1,36grant · 2026-03-24
    • FLAVIN JOHN LDirector · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
    • Metzger Michael ADirector · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
    • Lewis-Hall Freda CDirector · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
    • HUMPHREY RACHELDirector · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
    • Palani SanthoshDirector · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
    • Civik ThomasDirector, Interim CEO · Stock Option (Right to Buy) → Common StockAcquired 690 131 @ $1,49grant · 2026-02-03

    Actions

    Ask Handelsavisen

    — missing data
    Data sources
    • Market data
    • Market data cache
    • Issuer disclosures
    • Public news
    • Earnings transcripts
    • Consensus estimates
    • ESG data
    How metrics are computed
    • Return On Equity
      net_income / total_equity
    • Price To Book
      market_price / (adjusted_book_value / shares_outstanding_diluted)
    • Dilution Ratio
      (shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
    • Market Price
      input from market-data provider (delayed close or quote-shim mid)
    • Market Cap
      market_price * shares_outstanding_diluted
    • Ev To Revenue
      enterprise_value / revenue
    Source documents
    • Pyxis Oncology Inc Market data — financials · 2026-05-29
    • Pyxis Oncology Inc Market data — analyst estimates · 2026-05-29

    Ownership & reference

    Top holders

    • BlackRock Institutional Trust Company, N.A.Investment Managers · as of 2024-06-300,00 %$9M
    • UBS Financial Services, Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • Nuveen LLCInvestment Managers · as of 2024-12-310,00 %$0M
    • Geode Capital Management, L.L.C.Investment Managers · as of 2026-03-310,00 %$1M
    • Vanguard Capital Management, LLCInvestment Managers · as of 2025-12-310,00 %$3M
    • Bank of New York Mellon CorpInstitutional Investor · as of 2026-03-310,00 %$0M
    • Northern Trust Investments, Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • LPL Financial LLCInvestment Managers · as of 2026-03-310,00 %$0M
    • State Street Investment Management (US)Investment Managers · as of 2026-03-310,00 %$0M
    • Goldman Sachs Asset Management, L.P.Investment Managers · as of 2026-03-310,00 %$0M
    • Dimensional Fund Advisors, L.P.Investment Managers · as of 2026-03-310,00 %$0M
    • Morgan Stanley Smith Barney LLCInvestment Managers · as of 2026-03-310,00 %$0M
    • PNC Investments LLCInvestment Managers · as of 2026-03-310,00 %$0M
    • FMR LLCInstitutional Investor · as of 2026-03-310,00 %$0M
    • JONES FINANCIAL COMPANIES LLLPInstitutional Investor · as of 2026-03-310,00 %$0M
    • Wells Fargo AdvisorsBrokerage Firms · as of 2026-03-310,00 %$0M

    Insider activity

    Mixed / flat0 buys · 0 sellsnet $01 insiders · last 365d
    • Wadhane JitendraPrin Fin & Acct Officer · Common StockOther 109 461 · 2026-03-24

    Short positioning

    3.3Mshares short+42.1% vs prior
    3.11days to cover
    55.0%short of daily vol
    14.2Kfails-to-deliver
    as of 2026-07-15 · short-interest report (free)

    Geographic breakdown

    — missing data
    Listings · one canonical issuer all listings resolve to the canonical
    PYXS.OCanonical
    NASDAQ · USD

    Intel & risk

    PredictorBeat prob45 %Surprise+0,00Full forecast →
    peak dispatch · —
    OSINT findings
    Dilution riskLow
    Liquidity riskMedium
    Net cash is negative after subtracting total debt.
    Relationship graph
    PYXSPFE.TOPharmaceutical
    This companySectorPartners

    Evidence & claims

    From filings & derived data
    • Net margin (FY 2025-12-31): -574.5%Derived (calculated)
    • Cost of revenue (YoY) (2025-12-31 vs 2024-12-31): 402.7%Derived (calculated)
    • EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 3.0%Derived (calculated)
    • EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 3.0%Derived (calculated)
    • Total liabilities (YoY) (2025-12-31 vs 2024-12-31): 4.6%Derived (calculated)
    • Total assets (YoY) (2025-12-31 vs 2024-12-31): -41.8%Derived (calculated)
    • Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): -55.8%Derived (calculated)
    • R&D expense (YoY) (2025-12-31 vs 2024-12-31): 25.4%Derived (calculated)
    • Operating income (YoY) (2025-12-31 vs 2024-12-31): 5.6%Derived (calculated)
    • Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -10.1%Derived (calculated)
    • Net income (YoY) (2025-12-31 vs 2024-12-31): -3.0%Derived (calculated)
    • Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): -20.8%Derived (calculated)
    • Capex (YoY) (2025-12-31 vs 2024-12-31): -96.2%Derived (calculated)
    • Debt-to-equity (FY 2025-12-31): 0.71xDerived (calculated)
    • Current ratio (FY 2025-12-31): 3.41xDerived (calculated)
    • Return on assets (FY 2025-12-31): -87.0%Derived (calculated)
    • Revenue (YoY) (2025-12-31 vs 2024-12-31): -14.2%Derived (calculated)
    • Return on equity (FY 2025-12-31): -149.1%Derived (calculated)
    • Capex (annual): USD 9KSEC XBRL filing
    • Shareholders' equity (annual): USD 53.41MSEC XBRL filing
    • Net income (annual): USD -79.62MSEC XBRL filing
    • Revenue (annual): USD 13.86MSEC XBRL filing
    • Cash & equivalents (annual): USD 15.42MSEC XBRL filing
    • Operating income (annual): USD -84.42MSEC XBRL filing
    Showing 24 of 60 surfaced claims.
    Atomic claims from regulatory filings and derived calculations. Provenance shown as source kind only.

    The Thread

    Everything we know, in order
    2026-10-28EVENTUpcomingQ3 2026 earnings (expected) estimated date
    2026-06-30 03:38 UTCEARNINGSUpcomingForecast: earnings_forecast (90d)
    2026-06-15FILING8-K filing →
    2026-05-14FILING10-Q filing →
    2026-05-14FILING8-K filing →
    2026-04-30FILINGDEF 14A filing →
    2026-03-24 00:00 UTCINSIDER9 insider transactions — 2026-03 8 derivative
    2026-03-24INSIDERWadhane Jitendra transacted 109.5k sh — Prin Fin & Acct Officer
    2026-03-24INSIDERLewis-Hall Freda C acquired 45.9k sh Stock Option (Right to Buy) — Director
    2026-03-24INSIDERHUMPHREY RACHEL acquired 45.9k sh Stock Option (Right to Buy) — Director
    2026-03-24INSIDERPalani Santhosh acquired 45.9k sh Stock Option (Right to Buy) — Director
    2026-03-24INSIDERDupont Jakob acquired 45.9k sh Stock Option (Right to Buy) — Director
    2026-03-24INSIDERCline Darren S acquired 45.9k sh Stock Option (Right to Buy) — Director
    2026-03-24INSIDERWadhane Jitendra acquired 262.6k sh Stock Option (Right to Buy) — Prin Fin & Acct Officer
    2026-03-24INSIDERFLAVIN JOHN L acquired 45.9k sh Stock Option (Right to Buy) — Director
    2026-03-24INSIDERMetzger Michael A acquired 45.9k sh Stock Option (Right to Buy) — Director
    2026-03-23FILING10-K filing →
    2026-03-23FILING8-K filing →
    2026-02-06FILING8-K filing →
    2026-02-03 00:00 UTCINSIDER1 insider transaction — 2026-02 1 derivative
    2026-02-03INSIDERCivik Thomas acquired 690.1k sh Stock Option (Right to Buy) — Director, Interim CEO
    2025-12-18FILING8-K filing →
    2025-11-03FILING10-Q filing →
    2025-11-03FILING8-K filing →
    2025-08-14FILING10-Q filing →
    2025-08-14FILING8-K filing →
    2025-04-21 00:00 UTCINSIDER3 insider transactions — 2025-04
    2025-03-31 00:00 UTCINSIDER11 insider transactions — 2025-03 11 derivative
    2024-12-23 00:00 UTCINSIDER3 insider transactions — 2024-12 3 derivative
    2024-11-26 00:00 UTCINSIDER2 insider transactions — 2024-11 · net buy $174k
    The entity's full life in the product — typed, chronological, joined across Newspaper, Platform and Data. Our memory, made visible.
    Sources filings · IR · transcripts · market data · tier hybrid · as of 2026-08-04 Market data · Issuer disclosures · Public news · Earnings transcripts · Consensus estimates · ESG data Premium coverage