Pyxis Oncology Inc
Pyxis Oncology Inc is a biotechnology company focused on the development of novel therapeutics for the treatment of cancer, primarily through its pipeline of small molecule drug candidates.
Business. Pyxis Oncology Inc (PYXS.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding its operating segments and geographic revenue mix are not available.
Analyst recommendations
9 analysts · consensus BuyAt a glance
What drives this business
The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
News & coverage
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Analysis
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Upcoming catalysts
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- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
Pyxis Oncology Inc (PYXS.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding its operating segments and geographic revenue mix are not available.
Pyxis Oncology Inc has a market capitalization of $142.05 million and a price-to-book ratio of 2.66, indicating that the market values the company at a premium to its book value. The company's liquidity position is characterized as medium, with a current ratio of 3.41, suggesting it has sufficient short-term assets to cover its short-term liabilities. However, the company has a negative net cash position after subtracting total debt, which could pose a liquidity risk.
The company's profitability is currently negative, with a net loss of $79.62 million and an operating loss of $84.42 million. Its return on equity is -1.49, and return on assets is -0.87, both significantly below the typical performance metrics for the biotechnology industry. The company's gross profit margin is 82.8%, which is relatively high, but this is offset by substantial operating expenses.
Pyxis Oncology Inc does not disclose specific revenue segments or geographic breakdowns in the provided data. However, the company's operations are likely concentrated in the United States, as is common for biotechnology firms. The lack of detailed segment reporting limits the ability to assess geographic or product diversification.
The company's growth trajectory is uncertain, with no specific revenue growth rates provided. The company is in a development stage, and its future growth will depend on the success of its drug candidates in clinical trials and eventual commercialization. The company's capital expenditures are minimal, with only $9,000 spent in the latest period, indicating a focus on research and development rather than physical expansion.
The company faces several risk factors, including its negative net cash position and the inherent risks associated with drug development, such as clinical trial failures and regulatory hurdles. The risk of dilution is currently low, as the number of shares outstanding has not changed between basic and diluted shares. However, the company may need to raise additional capital, which could lead to future dilution.
Recent events include the publication of financial results and analyst estimates. Analysts have provided a mean price target of $6.88, with a median of $7.00, indicating a generally positive outlook despite the company's current financial challenges. The company has received a strong-buy recommendation from five analysts, suggesting that the market sees potential for future growth.
- Pyxis Oncology Inc is a biotechnology company with a focus on developing novel cancer therapeutics.
- The company is currently unprofitable, with significant net and operating losses.
- The company's liquidity position is medium, with a current ratio of 3.41, but it has a negative net cash position.
- Analysts have a generally positive outlook, with a mean price target of $6.88 and five strong-buy recommendations.
- The company's future growth is contingent on the success of its drug candidates in clinical trials and regulatory approvals.
Bull / Bear case
Generated · model-assistedIn focus — financials by report
Valuation
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -1,29 |
| Revenue | —no estimate | —no estimate | 43,750 USD |
| Operating income | —no estimate | —no estimate | -100,0M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- Net cash is negative after subtracting total debt.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Director · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
- Director · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
- Prin Fin & Acct Officer · Stock Option (Right to Buy) → Common StockAcquired 262 635 @ $1,36grant · 2026-03-24
- Director · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
- Director · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
- Director · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
- Director · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
- Director · Stock Option (Right to Buy) → Common StockAcquired 45 867 @ $1,36grant · 2026-03-24
- Director, Interim CEO · Stock Option (Right to Buy) → Common StockAcquired 690 131 @ $1,49grant · 2026-02-03
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Return On Equitynet_income / total_equity
- Price To Bookmarket_price / (adjusted_book_value / shares_outstanding_diluted)
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Market Priceinput from market-data provider (delayed close or quote-shim mid)
- Market Capmarket_price * shares_outstanding_diluted
- Ev To Revenueenterprise_value / revenue
- Pyxis Oncology Inc Market data — financials · 2026-05-29
- Pyxis Oncology Inc Market data — analyst estimates · 2026-05-29
Ownership & reference
Top holders
- Investment Managers · as of 2024-06-300,00 %$9M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2024-12-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2025-12-310,00 %$3M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Brokerage Firms · as of 2026-03-310,00 %$0M
Insider activity
- Prin Fin & Acct Officer · Common StockOther 109 461 · 2026-03-24
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Net margin (FY 2025-12-31): -574.5%Derived (calculated)
- Cost of revenue (YoY) (2025-12-31 vs 2024-12-31): 402.7%Derived (calculated)
- EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 3.0%Derived (calculated)
- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 3.0%Derived (calculated)
- Total liabilities (YoY) (2025-12-31 vs 2024-12-31): 4.6%Derived (calculated)
- Total assets (YoY) (2025-12-31 vs 2024-12-31): -41.8%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): -55.8%Derived (calculated)
- R&D expense (YoY) (2025-12-31 vs 2024-12-31): 25.4%Derived (calculated)
- Operating income (YoY) (2025-12-31 vs 2024-12-31): 5.6%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -10.1%Derived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): -3.0%Derived (calculated)
- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): -20.8%Derived (calculated)
- Capex (YoY) (2025-12-31 vs 2024-12-31): -96.2%Derived (calculated)
- Debt-to-equity (FY 2025-12-31): 0.71xDerived (calculated)
- Current ratio (FY 2025-12-31): 3.41xDerived (calculated)
- Return on assets (FY 2025-12-31): -87.0%Derived (calculated)
- Revenue (YoY) (2025-12-31 vs 2024-12-31): -14.2%Derived (calculated)
- Return on equity (FY 2025-12-31): -149.1%Derived (calculated)
- Capex (annual): USD 9KSEC XBRL filing
- Shareholders' equity (annual): USD 53.41MSEC XBRL filing
- Net income (annual): USD -79.62MSEC XBRL filing
- Revenue (annual): USD 13.86MSEC XBRL filing
- Cash & equivalents (annual): USD 15.42MSEC XBRL filing
- Operating income (annual): USD -84.42MSEC XBRL filing