Sangamo Therapeutics Inc
Sangamo Therapeutics Inc is a biotechnology company focused on developing gene-based therapeutics for serious diseases, primarily through its zinc finger nuclease (ZFN) technology platform.
Business. Sangamo Therapeutics Inc (SGMO.O) is a biotechnology company operating within the pharmaceuticals and medical research industry. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. The company does not report distinct operating segments or geographic revenue breakdowns in the provided data.
Analyst recommendations
5 analysts · consensus BuyAt a glance
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The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
News & coverage
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- Company
- EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
Sangamo Therapeutics Inc (SGMO.O) is a biotechnology company operating within the pharmaceuticals and medical research industry. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. The company does not report distinct operating segments or geographic revenue breakdowns in the provided data.
Sangamo Therapeutics operates with a negative equity position of -$14.27 million and a market capitalization of $49.38 million, indicating a highly leveraged and capital-intensive business model. The company's liquidity position is weak, with a current ratio of 0.84 and negative free cash flow of -$119.03 million, suggesting limited ability to meet short-term obligations without external financing. Despite holding $20.95 million in cash and equivalents, the company's operating cash flow is negative, and it has no long-term debt, which may limit its access to capital markets for growth initiatives.
Profitability metrics show significant underperformance relative to industry norms. Sangamo reported a net loss of $122.93 million and an operating loss of $121.24 million, with a return on equity of 8.62% and a negative return on assets of -2.06%. These figures suggest that the company is not generating sufficient returns to justify its equity or asset base, and its operating margin is effectively negative. The company's EBITDA multiple is negative (-0.23), further highlighting its unprofitable operations.
Geographically and segment-wise, Sangamo's revenue is not disclosed by region or business line in the available data, but its operations are concentrated in the biotechnology sector, with a focus on gene therapy and ZFN-based treatments. This concentration increases exposure to regulatory and clinical trial risks, as well as market adoption uncertainties.
Looking ahead, Sangamo's revenue is expected to remain under pressure, with no clear path to profitability in the near term. The company's operating cash flow and free cash flow are both negative, and its capital expenditures, while minimal at -$102,000, suggest limited investment in growth. The absence of long-term debt and the low dilution risk do not offset the company's weak liquidity and profitability.
Risk factors include the high cost of R&D, regulatory hurdles, and the competitive landscape in gene therapy. The company's reliance on external financing to fund operations increases its vulnerability to market volatility and investor sentiment. Analysts have assigned a mean price target of $3.81, with a median of $2.00, but the wide range from $1.25 to $10.00 reflects significant uncertainty about the company's future value. No immediate filing-based liquidity or dilution flags were detected, but the company's financial position remains precarious.
Recent events include the continued development of its ZFN technology and ongoing clinical trials, but no major product launches or regulatory approvals have been disclosed in the latest financial data. The company's strategy appears to be centered on advancing its pipeline through partnerships and collaborations, which may provide near-term funding but do not guarantee long-term success.
- Sangamo Therapeutics is a biotechnology company with a negative equity position and weak liquidity.
- The company is unprofitable, with a net loss of $122.93 million and a negative return on assets of -2.06%.
- Revenue is not disclosed by segment or geography, indicating a lack of diversification and potential concentration risk.
- Analysts have assigned a wide range of price targets, reflecting significant uncertainty about the company's future.
- The company's reliance on external financing and its high R&D costs pose ongoing risks to its financial stability.
Bull / Bear case
Generated · model-assistedIn focus — financials by report
Valuation
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -0,19 |
| Revenue | —no estimate | —no estimate | 67,6M USD |
| Operating income | —no estimate | —no estimate | -95,5M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- Head of Research & Technology · Stock Option (Right to Buy) → Common StockAcquired 225 000 @ $0,26grant · 2026-04-01
- Director, PRESIDENT, CEO AND DIRECTOR · Stock Option (Right to Buy) → Common StockAcquired 2 500 000 @ $0,26grant · 2026-04-01
- SVP, CHIEF LEGAL OFFICER, SECY · Stock Option (Right to Buy) → Common StockAcquired 800 000 @ $0,26grant · 2026-04-01
- SVP-CHIEF DEVELOPMENT OFFICER · Stock Option (Right to Buy) → Common StockAcquired 800 000 @ $0,26grant · 2026-04-01
- Principal Accounting Officer · Stock Option (Right to Buy) → Common StockAcquired 225 000 @ $0,26grant · 2026-04-01
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Return On Equitynet_income / total_equity
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Market Priceinput from market-data provider (delayed close or quote-shim mid)
- Market Capmarket_price * shares_outstanding_diluted
- Ev To Revenueenterprise_value / revenue
- Net Cashcash_and_equivalents + short_term_investments - short_term_debt - long_term_debt
- Sangamo Therapeutics Inc Market data — financials · 2026-05-29
- Sangamo Therapeutics Inc Market data — analyst estimates · 2026-05-29
Ownership & reference
Top holders
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2025-12-310,00 %$5M
- Investment Managers · as of 2026-03-310,00 %$1M
- Funds · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2024-06-300,00 %$2M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Brokerage Firms · as of 2026-03-310,00 %$0M
Leadership
- Alexander D. MacraePresident, Chief Executive Officer, Director
Insider activity
- SVP-CHIEF DEVELOPMENT OFFICER · Common StockOther 4 036 @ $0,17$703 · 2026-05-25
- Director, PRESIDENT, CEO AND DIRECTOR · Common StockOther 12 613 @ $0,17$2K · 2026-05-25
- Principal Accounting Officer · Common StockOther 1 919 @ $0,17$334 · 2026-05-25
- Head of Research & Technology · Common StockOther 1 630 @ $0,17$284 · 2026-05-25
- SVP, CHIEF LEGAL OFFICER, SECY · Common StockOther 4 036 @ $0,17$703 · 2026-05-25
- Head of Research & Technology · Common StockSold 69 827 @ $0,25$18K · 2026-04-22
- SVP-CHIEF DEVELOPMENT OFFICER · Common StockSold 345 942 @ $0,26$89K · 2026-04-21
- Director, PRESIDENT, CEO AND DIRECTOR · Common StockOther 33 637 @ $0,47$16K · 2026-02-25
- SVP, CHIEF LEGAL OFFICER, SECY · Common StockOther 12 354 @ $0,47$6K · 2026-02-25
- Principal Accounting Officer · Common StockOther 5 119 @ $0,47$2K · 2026-02-25
- Head of Research & Technology · Common StockOther 5 119 @ $0,47$2K · 2026-02-25
- SVP-CHIEF DEVELOPMENT OFFICER · Common StockOther 12 354 @ $0,47$6K · 2026-02-25
- SVP, CHIEF LEGAL OFFICER, SECY · Common StockOther 1 650 @ $0,47$780 · 2026-02-24
- SVP-CHIEF DEVELOPMENT OFFICER · Common StockOther 2 063 @ $0,47$975 · 2026-02-24
- Director, PRESIDENT, CEO AND DIRECTOR · Common StockOther 5 291 @ $0,47$2K · 2026-02-24
- Principal Accounting Officer · Common StockOther 666 @ $0,47$315 · 2026-02-24
- Head of Research & Technology · Common StockOther 832 @ $0,47$393 · 2026-02-24
- SVP-CHIEF DEVELOPMENT OFFICER · Common StockOther 36 676 @ $0,40$15K · 2026-01-22
- Principal Accounting Officer · Common StockOther 7 721 @ $0,40$3K · 2026-01-22
- Head of Research & Technology · Common StockOther 7 721 @ $0,40$3K · 2026-01-22
- PRINCIPAL FINANCIAL OFFICER · Common StockOther 36 676 @ $0,40$15K · 2026-01-22
- Director, PRESIDENT, CEO AND DIRECTOR · Common StockOther 102 950 @ $0,40$41K · 2026-01-22
- SVP, CHIEF LEGAL OFFICER, SECY · Common StockOther 36 676 @ $0,40$15K · 2026-01-22
- Principal Accounting Officer · Common StockOther 578 @ $0,42$241 · 2025-11-24
- SVP, CHIEF LEGAL OFFICER, SECY · Common StockOther 2 035 @ $0,42$848 · 2025-11-24
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- Net margin (FY 2025-12-31): -310.8%Derived (calculated)
- Operating income (YoY) (2025-12-31 vs 2024-12-31): -16.6%Derived (calculated)
- Revenue (YoY) (2025-12-31 vs 2024-12-31): -31.6%Derived (calculated)
- Total assets (YoY) (2025-12-31 vs 2024-12-31): -41.2%Derived (calculated)
- R&D expense (YoY) (2025-12-31 vs 2024-12-31): 1.0%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -44.8%Derived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): -25.5%Derived (calculated)
- EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 10.2%Derived (calculated)
- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 10.2%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): -162.7%Derived (calculated)
- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): -50.0%Derived (calculated)
- Capex (YoY) (2025-12-31 vs 2024-12-31): -61.8%Derived (calculated)
- Debt-to-equity (FY 2025-12-31): -5.19xDerived (calculated)
- Return on equity (FY 2025-12-31): 861.6%Derived (calculated)
- Return on assets (FY 2025-12-31): -205.8%Derived (calculated)
- Current ratio (FY 2025-12-31): 0.84xDerived (calculated)
- Total liabilities (YoY) (2025-12-31 vs 2024-12-31): -6.2%Derived (calculated)
- Current liabilities (annual): USD 42.47MSEC XBRL filing
- Shares outstanding (annual): 350.69MSEC XBRL filing
- Shareholders' equity (annual): USD -14.27MSEC XBRL filing
- Total liabilities (annual): USD 74.01MSEC XBRL filing
- Current assets (annual): USD 35.83MSEC XBRL filing
- EPS (diluted) (annual): USD-PER-SHARES -0SEC XBRL filing
- Total operating expenses (annual): USD 160.79MSEC XBRL filing