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INDICATIVE · SAMPLE DATA
SGMO$0.1259

Sangamo Therapeutics Inc

Biotechnology & Medical ResearchVerified

Sangamo Therapeutics operates with a negative equity position of -$14.27 million and a market capitalization of $49.38 million, indicating a highly leveraged and capital-intensive business model. The company's liquidity position is weak, with a current ratio of 0.84 and negative free cash flow of -$119.03 million, suggesting limited ability to meet short-term obligations without external financing. Despite holding $20.95 million in cash and equivalents, the company's operating cash flow is negative, and it has no long-term debt, which may limit its access to capital markets for growth initiatives. Profitability metrics show significant underperformance relative to industry norms. Sangamo reported a net loss of $122.93 million and an operating loss of $121.24 million, with a return on equity of 8.62% and a negative return on assets of -2.06%. These figures suggest that the company is not generating sufficient returns to justify its equity or asset base, and its operating margin is effectively negative. The company's EBITDA multiple is negative (-0.23), further highlighting its unprofitable operations. Geographically and segment-wise, Sangamo's revenue is not disclosed by region or business line in the available data, but its operations are concentrated in the biotechnology sector, with a focus on gene therapy and ZFN-based treatments. This concentration increases exposure to regulatory and clinical trial risks, as well as market adoption uncertainties. Looking ahead, Sangamo's revenue is expected to remain under pressure, with no clear path to profitability in the near term. The company's operating cash flow and free cash flow are both negative, and its capital expenditures, while minimal at -$102,000, suggest limited investment in growth. The absence of long-term debt and the low dilution risk do not offset the company's weak liquidity and profitability. Risk factors include the high cost of R&D, regulatory hurdles, and the competitive landscape in gene therapy. The company's reliance on external financing to fund operations increases its vulnerability to market volatility and investor sentiment. Analysts have assigned a mean price target of $3.81, with a median of $2.00, but the wide range from $1.25 to $10.00 reflects significant uncertainty about the company's future value. No immediate filing-based liquidity or dilution flags were detected, but the company's financial position remains precarious. Recent events include the continued development of its ZFN technology and ongoing clinical trials, but no major product launches or regulatory approvals have been disclosed in the latest financial data. The company's strategy appears to be centered on advancing its pipeline through partnerships and collaborations, which may provide near-term funding but do not guarantee long-term success.

30-day price · SGMO-0.02 (-11.6%)
Low$0.12High$0.22Close$0.18As of5 May, 00:00 UTC
Profile
CompanySangamo Therapeutics Inc
TickerSGMO.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Sangamo Therapeutics Inc is a biotechnology company focused on developing gene-based therapeutics for serious diseases, primarily through its zinc finger nuclease (ZFN) technology platform.

Classification. Sangamo is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

Sangamo Therapeutics operates with a negative equity position of -$14.27 million and a market capitalization of $49.38 million, indicating a highly leveraged and capital-intensive business model. The company's liquidity position is weak, with a current ratio of 0.84 and negative free cash flow of -$119.03 million, suggesting limited ability to meet short-term obligations without external financing. Despite holding $20.95 million in cash and equivalents, the company's operating cash flow is negative, and it has no long-term debt, which may limit its access to capital markets for growth initiatives. Profitability metrics show significant underperformance relative to industry norms. Sangamo reported a net loss of $122.93 million and an operating loss of $121.24 million, with a return on equity of 8.62% and a negative return on assets of -2.06%. These figures suggest that the company is not generating sufficient returns to justify its equity or asset base, and its operating margin is effectively negative. The company's EBITDA multiple is negative (-0.23), further highlighting its unprofitable operations. Geographically and segment-wise, Sangamo's revenue is not disclosed by region or business line in the available data, but its operations are concentrated in the biotechnology sector, with a focus on gene therapy and ZFN-based treatments. This concentration increases exposure to regulatory and clinical trial risks, as well as market adoption uncertainties. Looking ahead, Sangamo's revenue is expected to remain under pressure, with no clear path to profitability in the near term. The company's operating cash flow and free cash flow are both negative, and its capital expenditures, while minimal at -$102,000, suggest limited investment in growth. The absence of long-term debt and the low dilution risk do not offset the company's weak liquidity and profitability. Risk factors include the high cost of R&D, regulatory hurdles, and the competitive landscape in gene therapy. The company's reliance on external financing to fund operations increases its vulnerability to market volatility and investor sentiment. Analysts have assigned a mean price target of $3.81, with a median of $2.00, but the wide range from $1.25 to $10.00 reflects significant uncertainty about the company's future value. No immediate filing-based liquidity or dilution flags were detected, but the company's financial position remains precarious. Recent events include the continued development of its ZFN technology and ongoing clinical trials, but no major product launches or regulatory approvals have been disclosed in the latest financial data. The company's strategy appears to be centered on advancing its pipeline through partnerships and collaborations, which may provide near-term funding but do not guarantee long-term success.
Key takeaways
  • Sangamo Therapeutics is a biotechnology company with a negative equity position and weak liquidity.
  • The company is unprofitable, with a net loss of $122.93 million and a negative return on assets of -2.06%.
  • Revenue is not disclosed by segment or geography, indicating a lack of diversification and potential concentration risk.
  • Analysts have assigned a wide range of price targets, reflecting significant uncertainty about the company's future.
  • The company's reliance on external financing and its high R&D costs pose ongoing risks to its financial stability.
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Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$39.6M
Gross profit
Operating income-$121.2M
Net income-$122.9M
R&D
SG&A
D&A
SBC
Operating cash flow-$97.2M
CapEx-$102.0k
Free cash flow-$119.0M
Total assets$59.7M
Total liabilities$74.0M
Total equity-$14.3M
Cash & equivalents$20.9M
Long-term debt$0.00
Valuation
Market price$0.12
Market cap$49.4M
Enterprise value$28.4M
P/E
Reported non-GAAP P/E
EV/Revenue0.7
EV/Op income
EV/OCF
P/B
P/Tangible book
Tangible book-$14.3M
Net cash$20.9M
Current ratio0.8
Debt/Equity-0.0
ROA-2.1%
ROE8.6%
Cash conversion79.0%
CapEx/Revenue-0.3%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 693 companies
MetricSGMOActivity
Op margin-306.5%2.4% medp25 -91.8% · p75 12.5%bottom quartile
Net margin-310.8%1.2% medp25 -98.4% · p75 10.4%bottom quartile
Gross margin45.6% medp25 29.8% · p75 66.7%
CapEx / revenue-0.3%-5.2% medp25 -15.8% · p75 -1.7%top quartile
Debt / equity-0.0%9.3% medp25 0.1% · p75 43.8%bottom quartile
Observations
IR observations
Mean price target3.81 USD
Median price target2.00 USD
High price target10.00 USD
Low price target1.25 USD
Mean recommendation2.20 (1=strong buy, 5=strong sell)
Strong-buy count1.00
Buy count2.00
Hold count2.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-0.19 USD
Last actual EPS-0.44 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod financials
no public URL
2026-05-16 17:37 UTC#f0e46665
Source: analysis-pipeline (hybrid)Generated: 2026-05-29 09:52 UTCJob: e9a62c0e