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INDICATIVE · SAMPLE DATA
SANN59

Santhera Pharmaceuticals Holding AG

PharmaceuticalsVerified

Santhera Pharmaceuticals Holding AG operates with a negative equity position of CHF -11.82 million and a debt-to-equity ratio of -1.37, indicating a capital structure heavily reliant on liabilities rather than equity. The company holds CHF 22.44 million in cash and equivalents, which is partially offset by total liabilities of CHF 159.90 million. The operating cash flow is negative at CHF -34.76 million, suggesting ongoing operational cash burn. Profitability metrics are not available due to the company's current stage of development and lack of commercialized products. The company is focused on research and development, with no disclosed revenue from product sales. This aligns with the industry_config for pharmaceutical firms in early development, where revenue is typically derived from partnerships and grants rather than product sales. Geographically, Santhera operates through wholly owned subsidiaries in Switzerland, the United States, Canada, Germany, and Finland. However, the financial snapshot does not provide a breakdown of revenue by region, making it difficult to assess geographic concentration risk. The company's operations are primarily focused on the development of treatments for neuromuscular and mitochondrial diseases. The company's growth trajectory is speculative, as it is in the research and development phase with no commercialized products. The outlook for the current fiscal year does not provide numeric deltas, but the company's reliance on partnerships and grants for funding suggests a high degree of uncertainty in future revenue streams. Risk factors include low liquidity and the absence of immediate filing-based liquidity or dilution flags. The company's negative equity and high liabilities indicate a significant financial risk. The dilution potential is currently low, but the company may need to raise additional capital through equity issuance, which could dilute existing shareholders. Recent events include the company's continued focus on the development of gene therapy for LAMA2-deficient congenital muscular dystrophy (CMD). The company has not disclosed any recent filings or transcripts that would indicate significant changes in its business strategy or financial position.

30-day price · SANN(missing data)
No daily-bar history available from current data sources. Alternate source pending.
Profile
CompanySanthera Pharmaceuticals Holding AG
TickerSANN.S
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryPharmaceuticals
AI analysis

Business. Santhera Pharmaceuticals Holding AG is a Switzerland-based company engaged in the pharmaceutical sector, focusing on the research, development, and commercialization of pharmaceutical products for the treatment of neuromuscular and mitochondrial diseases, such as Duchenne muscular dystrophy (DMD) and cystic fibrosis (CF).

Classification. Santhera is classified under the Healthcare economic sector, specifically in the Pharmaceuticals & Medical Research business sector, with a high confidence level of 0.92.

Santhera Pharmaceuticals Holding AG operates with a negative equity position of CHF -11.82 million and a debt-to-equity ratio of -1.37, indicating a capital structure heavily reliant on liabilities rather than equity. The company holds CHF 22.44 million in cash and equivalents, which is partially offset by total liabilities of CHF 159.90 million. The operating cash flow is negative at CHF -34.76 million, suggesting ongoing operational cash burn. Profitability metrics are not available due to the company's current stage of development and lack of commercialized products. The company is focused on research and development, with no disclosed revenue from product sales. This aligns with the industry_config for pharmaceutical firms in early development, where revenue is typically derived from partnerships and grants rather than product sales. Geographically, Santhera operates through wholly owned subsidiaries in Switzerland, the United States, Canada, Germany, and Finland. However, the financial snapshot does not provide a breakdown of revenue by region, making it difficult to assess geographic concentration risk. The company's operations are primarily focused on the development of treatments for neuromuscular and mitochondrial diseases. The company's growth trajectory is speculative, as it is in the research and development phase with no commercialized products. The outlook for the current fiscal year does not provide numeric deltas, but the company's reliance on partnerships and grants for funding suggests a high degree of uncertainty in future revenue streams. Risk factors include low liquidity and the absence of immediate filing-based liquidity or dilution flags. The company's negative equity and high liabilities indicate a significant financial risk. The dilution potential is currently low, but the company may need to raise additional capital through equity issuance, which could dilute existing shareholders. Recent events include the company's continued focus on the development of gene therapy for LAMA2-deficient congenital muscular dystrophy (CMD). The company has not disclosed any recent filings or transcripts that would indicate significant changes in its business strategy or financial position.
Key takeaways
  • Santhera Pharmaceuticals is in the research and development phase with no commercialized products, relying on partnerships and grants for funding.
  • The company has a negative equity position and a high debt-to-equity ratio, indicating a capital structure heavily reliant on liabilities.
  • The company's geographic exposure is broad but lacks a detailed revenue concentration breakdown.
  • Growth is speculative, with no commercialized products and no disclosed numeric deltas for the current fiscal year.
  • The company faces low liquidity and potential future dilution if additional capital is required.
  • Recent events do not indicate significant changes in the company's business strategy or financial position.
  • --
  • ## RATIONALES
Financial snapshot
PeriodHA-latest
CurrencyCHF
Revenue$77.2M
Gross profit
Operating income
Net income
R&D
SG&A
D&A
SBC
Operating cash flow-$34.8M
CapEx-$52.0k
Free cash flow
Total assets
Total liabilities$159.9M
Total equity-$11.8M
Cash & equivalents$22.4M
Long-term debt$16.2M
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY0
FY-1
FY-2
FY-3
FY-4
PeriodGross %Op %Net %FCF %
FY0
FY-1
FY-2
FY-3
FY-4
PeriodAssetsEquityCashDebt
FY0
FY-1
FY-2
FY-3
FY-4
PeriodOCFCapExFCFSBC
FY0
FY-1
FY-2
FY-3
FY-4
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodGross %Op %Net %FCF %
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodAssetsEquityCashDebt
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodOCFCapExFCFSBC
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
Valuation
Market price
Market cap
Enterprise value
P/E
Reported non-GAAP P/E
EV/Revenue
EV/Op income
EV/OCF
P/B
P/Tangible book
Tangible book
Net cash$6.2M
Current ratio
Debt/Equity-1.4
ROA
ROE
Cash conversion
CapEx/Revenue-0.1%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Pharmaceuticals & Medical Research · cohort 1 companies
MetricSANNActivity
Op margin-2.9% medp25 -218.9% · p75 9.6%
Net margin28.2% medp25 28.2% · p75 28.2%
Gross margin47.8% medp25 27.6% · p75 68.9%
CapEx / revenue-0.1%6.6% medp25 6.6% · p75 6.6%bottom quartile
Debt / equity-137.0%271.5% medp25 271.5% · p75 271.5%bottom quartile
Observations
IR observations
Mean price target30.00 CHF
Median price target30.00 CHF
High price target30.00 CHF
Low price target30.00 CHF
Mean recommendation2.00 (1=strong buy, 5=strong sell)
Strong-buy count0.00
Buy count1.00
Hold count0.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate0.09 CHF
Last actual EPS-3.78 CHF
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-04 13:36 UTC#8fa41768
Source: analysis-pipeline (hybrid)Generated: 2026-05-04 13:38 UTCJob: cde1fe13