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INDICATIVE · SAMPLE DATA
SPRB$59.0059

Spruce Biosciences, Inc

Biotechnology & Medical ResearchVerified

Spruce Biosciences maintains a strong liquidity position, with $81.15 million in cash and equivalents, significantly exceeding its total liabilities of $20.92 million, resulting in a current ratio of 4.67. The company's price-to-book ratio of 2.39 suggests a premium valuation relative to its book value, while the debt-to-equity ratio of 0.04 indicates minimal leverage. The company's profitability remains negative, with a net loss of $11.63 million and an operating loss of $12.63 million in the latest reporting period. Return on equity (ROE) and return on assets (ROA) are -17.45% and -13.28%, respectively, indicating poor capital efficiency and asset utilization. These metrics fall below the typical performance benchmarks for the biotechnology and medical research industry, where positive returns are often necessary to justify high valuations. Spruce Biosciences derives its revenue primarily from the sale of diagnostic tests, with a geographic focus on the United States. The company's revenue concentration is not disclosed in the available data, but its operations are likely subject to regulatory and market dynamics in the U.S. healthcare sector. The company's growth trajectory is uncertain, with no specific revenue growth projections provided in the available data. However, the high price targets from analysts, ranging from $140 to $283 per share, suggest optimism about the company's long-term potential. The mean price target of $186.60 implies a significant upside from the current market price of $59. Risk factors for Spruce Biosciences include the volatility of the biotechnology sector, regulatory changes affecting diagnostic testing, and the potential for dilution if the company raises additional capital. The risk assessment indicates low liquidity and dilution risk, with no immediate filing-based flags detected. The company's low dilution risk is supported by the absence of recent equity issuances or shelf registration activity in the available data. Recent events include the continued demand for diagnostic testing, particularly in the context of the ongoing global health environment. The company has not disclosed any major new product launches or strategic partnerships in the latest filings, but the high analyst price targets suggest confidence in its future performance.

30-day price · SPRB-6.54 (-10.4%)
Low$51.36High$74.00Close$56.50As of10 May, 00:00 UTC
Profile
CompanySpruce Biosciences, Inc
TickerSPRB.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Spruce Biosciences, Inc develops and commercializes diagnostic tests for the detection of SARS-CoV-2 and other infectious diseases, primarily generating revenue through the sale of its diagnostic kits and related services.

Classification. Spruce Biosciences is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

Spruce Biosciences maintains a strong liquidity position, with $81.15 million in cash and equivalents, significantly exceeding its total liabilities of $20.92 million, resulting in a current ratio of 4.67. The company's price-to-book ratio of 2.39 suggests a premium valuation relative to its book value, while the debt-to-equity ratio of 0.04 indicates minimal leverage. The company's profitability remains negative, with a net loss of $11.63 million and an operating loss of $12.63 million in the latest reporting period. Return on equity (ROE) and return on assets (ROA) are -17.45% and -13.28%, respectively, indicating poor capital efficiency and asset utilization. These metrics fall below the typical performance benchmarks for the biotechnology and medical research industry, where positive returns are often necessary to justify high valuations. Spruce Biosciences derives its revenue primarily from the sale of diagnostic tests, with a geographic focus on the United States. The company's revenue concentration is not disclosed in the available data, but its operations are likely subject to regulatory and market dynamics in the U.S. healthcare sector. The company's growth trajectory is uncertain, with no specific revenue growth projections provided in the available data. However, the high price targets from analysts, ranging from $140 to $283 per share, suggest optimism about the company's long-term potential. The mean price target of $186.60 implies a significant upside from the current market price of $59. Risk factors for Spruce Biosciences include the volatility of the biotechnology sector, regulatory changes affecting diagnostic testing, and the potential for dilution if the company raises additional capital. The risk assessment indicates low liquidity and dilution risk, with no immediate filing-based flags detected. The company's low dilution risk is supported by the absence of recent equity issuances or shelf registration activity in the available data. Recent events include the continued demand for diagnostic testing, particularly in the context of the ongoing global health environment. The company has not disclosed any major new product launches or strategic partnerships in the latest filings, but the high analyst price targets suggest confidence in its future performance.
Key takeaways
  • Spruce Biosciences has a strong liquidity position with $81.15 million in cash and equivalents, but it is currently unprofitable with a net loss of $11.63 million.
  • The company's price-to-book ratio of 2.39 and debt-to-equity ratio of 0.04 indicate a premium valuation with minimal leverage.
  • Analysts have assigned high price targets, ranging from $140 to $283 per share, suggesting optimism about the company's long-term potential.
  • The company's profitability metrics, including ROE and ROA, are negative, indicating poor capital efficiency and asset utilization.
  • Spruce Biosciences operates in a high-growth but volatile sector, with revenue primarily derived from diagnostic test sales in the U.S.
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  • # RATIONALES
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Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$2.0M
Gross profit
Operating income-$12.6M
Net income-$11.6M
R&D
SG&A
D&A
SBC
Operating cash flow-$15.0M
CapEx
Free cash flow-$11.6M
Total assets$87.5M
Total liabilities$20.9M
Total equity$66.6M
Cash & equivalents$81.2M
Long-term debt$2.9M
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY-4-$42.1M-$42.3M-$42.3M
FY-3-$47.3M-$46.2M-$46.1M
FY-2$10.1M-$52.0M-$47.9M-$47.9M
FY-1$4.9M-$56.2M-$53.0M-$53.0M
FY0$0.00-$36.5M-$39.0M-$38.9M
PeriodGross %Op %Net %FCF %
FY-4
FY-3
FY-2
FY-1
FY0
PeriodAssetsEquityCashDebt
FY-4$126.5M$111.4M$42.7M
FY-3$85.6M$68.5M$24.5M
FY-2$103.9M$76.5M$96.3M
FY-1$45.2M$28.8M$38.8M
FY0$53.0M$42.5M$48.9M
PeriodOCFCapExFCFSBC
FY-4-$35.9M-$93.0k-$42.3M
FY-3-$41.7M-$8.0k-$46.1M
FY-2-$33.3M-$7.0k-$47.9M
FY-1-$56.0M$0.00-$53.0M
FY0-$33.3M-$38.9M
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ-7$2.0M-$12.6M-$11.6M-$11.6M
FQ-6$1.6M-$10.0M-$9.2M-$9.2M
FQ-5$602.0k-$9.4M-$8.7M-$8.7M
FQ-4$697.0k-$24.1M-$23.6M-$23.6M
FQ-3$0.00-$14.5M-$14.0M-$14.0M
FQ-2$0.00-$2.7M-$2.1M-$2.1M
FQ-1$0.00-$8.2M-$8.2M-$8.2M
FQ0$0.00-$11.1M-$14.6M-$14.6M
PeriodGross %Op %Net %FCF %
FQ-7
FQ-6
FQ-5
FQ-4
FQ-3
FQ-2
FQ-1
FQ0
PeriodAssetsEquityCashDebt
FQ-7$87.5M$66.6M$81.2M
FQ-6$75.5M$59.2M$69.7M
FQ-5$65.1M$51.6M$60.1M
FQ-4$45.2M$28.8M$38.8M
FQ-3$31.6M$15.3M$25.6M
FQ-2$21.8M$13.2M$16.4M
FQ-1$15.3M$5.4M$10.7M
FQ0$53.0M$42.5M$48.9M
PeriodOCFCapExFCFSBC
FQ-7-$15.0M-$11.6M
FQ-6-$26.1M-$9.2M
FQ-5-$35.3M$0.00-$8.7M
FQ-4-$56.0M$0.00-$23.6M
FQ-3-$12.7M-$14.0M
FQ-2-$21.6M-$2.1M
FQ-1-$26.9M-$8.2M
FQ0-$33.3M-$14.6M
Valuation
Market price$59.00
Market cap$159.4M
Enterprise value$81.2M
P/E
Reported non-GAAP P/E
EV/Revenue40.6
EV/Op income
EV/OCF
P/B2.4
P/Tangible book2.4
Tangible book$66.6M
Net cash$78.2M
Current ratio4.7
Debt/Equity0.0
ROA-13.3%
ROE-17.4%
Cash conversion1.3%
CapEx/Revenue
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Healthcare Diagnostics · cohort 170 companies
MetricSPRBActivity
Op margin-631.0%-227.5% medp25 -1250.6% · p75 -3.5%below median
Net margin-580.7%-194.5% medp25 -1233.8% · p75 0.8%below median
Gross margin53.0% medp25 25.9% · p75 75.7%
CapEx / revenue-8.2% medp25 -35.2% · p75 -2.5%
Debt / equity4.0%1.2% medp25 0.0% · p75 17.4%above median
Observations
IR observations
Mean price target186.60 USD
Median price target170.00 USD
High price target283.00 USD
Low price target140.00 USD
Mean recommendation1.60 (1=strong buy, 5=strong sell)
Strong-buy count2.00
Buy count3.00
Hold count0.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-36.72 USD
Last actual EPS-50.83 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-16 14:03 UTC#216719df
Market quoteclose USD 56.57 · shares 0.00B diluted
no public URL
2026-05-16 14:03 UTC#9d060838
Source: analysis-pipeline (hybrid)Generated: 2026-05-29 13:20 UTCJob: b6e7f539