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INDICATIVE · SAMPLE DATA
TGTX$36.1058

TGTX.O

PharmaceuticalsVerified

TGTX's capital structure is characterized by a market cap of $5.53 billion and a price-to-book ratio of 8.53, indicating a premium valuation relative to its book value. The company's liquidity position is mixed, with $79.15 million in cash and equivalents but a negative net cash position after subtracting $245.65 million in long-term debt. Free cash flow of $447.02 million suggests strong cash generation, but operating cash flow is negative at -$24.77 million, signaling potential near-term operational challenges. Profitability metrics show a return on equity (ROE) of 69.01% and a return on assets (ROA) of 42.06%, both significantly above the industry median for biotechnology firms. The company's gross margin of 83.6% (calculated from gross profit of $515.57 million on revenue of $616.29 million) is robust, but its operating margin of 19.99% is lower, reflecting high R&D and SG&A expenses typical in the sector. Geographically, TGTX's revenue is concentrated in the United States, with no material international operations disclosed. The company's product portfolio is currently centered on Tavneos, with no other commercialized products contributing to revenue. This concentration in a single product and market increases exposure to regulatory, reimbursement, and competitive risks. Growth trajectory is positive, with revenue of $616.29 million in the latest period. Analysts project a mean price target of $44.33, implying a 22.7% upside from the current market price of $36.10. The company's capital expenditure of -$214,000 suggests minimal investment in physical assets, consistent with a biotech firm focused on R&D rather than manufacturing infrastructure. Risk factors include a medium liquidity rating due to the negative net cash position and a debt-to-equity ratio of 0.38. The company has a low dilution risk, with basic and diluted shares outstanding aligned at 153.09 million. No recent dilutive events are disclosed, and the risk assessment does not flag near-term dilution pressure. Recent events include the continued commercialization of Tavneos and ongoing clinical trials for additional indications. The company has not disclosed any material regulatory or litigation risks in the latest filings, but the biotech sector is inherently subject to high R&D failure rates and regulatory uncertainty.

30-day price · TGTX+4.52 (+13.2%)
Low$33.23High$44.65Close$38.82As of29 May, 00:00 UTC
Profile
CompanyTGTX.O
TickerTGTX.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryPharmaceuticals
AI analysis

Business. TGTX.O is a biotechnology company focused on the development and commercialization of therapies for autoimmune and inflammatory diseases, primarily through its lead product, Tavneos (avacopan), which is approved for the treatment of ANCA-associated vasculitis.

Classification. TGTX.O is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Pharmaceuticals industry, with a classification confidence of 0.92.

TGTX's capital structure is characterized by a market cap of $5.53 billion and a price-to-book ratio of 8.53, indicating a premium valuation relative to its book value. The company's liquidity position is mixed, with $79.15 million in cash and equivalents but a negative net cash position after subtracting $245.65 million in long-term debt. Free cash flow of $447.02 million suggests strong cash generation, but operating cash flow is negative at -$24.77 million, signaling potential near-term operational challenges. Profitability metrics show a return on equity (ROE) of 69.01% and a return on assets (ROA) of 42.06%, both significantly above the industry median for biotechnology firms. The company's gross margin of 83.6% (calculated from gross profit of $515.57 million on revenue of $616.29 million) is robust, but its operating margin of 19.99% is lower, reflecting high R&D and SG&A expenses typical in the sector. Geographically, TGTX's revenue is concentrated in the United States, with no material international operations disclosed. The company's product portfolio is currently centered on Tavneos, with no other commercialized products contributing to revenue. This concentration in a single product and market increases exposure to regulatory, reimbursement, and competitive risks. Growth trajectory is positive, with revenue of $616.29 million in the latest period. Analysts project a mean price target of $44.33, implying a 22.7% upside from the current market price of $36.10. The company's capital expenditure of -$214,000 suggests minimal investment in physical assets, consistent with a biotech firm focused on R&D rather than manufacturing infrastructure. Risk factors include a medium liquidity rating due to the negative net cash position and a debt-to-equity ratio of 0.38. The company has a low dilution risk, with basic and diluted shares outstanding aligned at 153.09 million. No recent dilutive events are disclosed, and the risk assessment does not flag near-term dilution pressure. Recent events include the continued commercialization of Tavneos and ongoing clinical trials for additional indications. The company has not disclosed any material regulatory or litigation risks in the latest filings, but the biotech sector is inherently subject to high R&D failure rates and regulatory uncertainty.
Key takeaways
  • TGTX's strong ROE and ROA highlight its efficient use of equity and assets, but its negative operating cash flow raises concerns about short-term liquidity.
  • The company's valuation is premium, with a P/B of 8.53 and a P/E of 12.36, suggesting market confidence in its growth potential.
  • Revenue concentration in a single product and market increases vulnerability to competitive and regulatory shifts.
  • Analysts are optimistic, with a mean price target of $44.33 and a strong-buy rating from one of eight analysts.
  • The company's low debt and high free cash flow provide flexibility for R&D investment or strategic acquisitions.
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  • # RATIONALES
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Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$616.3M
Gross profit$515.6M
Operating income$123.3M
Net income$447.2M
R&D
SG&A
D&A
SBC
Operating cash flow-$24.8M
CapEx-$214.0k
Free cash flow$447.0M
Total assets$1.06B
Total liabilities$415.2M
Total equity$648.0M
Cash & equivalents$79.1M
Long-term debt$245.6M
Valuation
Market price$36.10
Market cap$5.53B
Enterprise value$5.69B
P/E12.4
Reported non-GAAP P/E
EV/Revenue9.2
EV/Op income46.2
EV/OCF
P/B8.5
P/Tangible book8.5
Tangible book$648.0M
Net cash-$166.5M
Current ratio4.1
Debt/Equity0.4
ROA42.1%
ROE69.0%
Cash conversion-6.0%
CapEx/Revenue-0.0%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskMedium
  • Net cash is negative after subtracting total debt.
Industry benchmarks
Activity: Pharmaceuticals · cohort 779 companies
MetricTGTXActivity
Op margin20.0%7.7% medp25 -2.4% · p75 15.5%top quartile
Net margin72.6%5.9% medp25 -3.8% · p75 12.8%top quartile
Gross margin83.7%45.5% medp25 31.1% · p75 62.9%top quartile
R&D / revenue529.2% medp25 465.2% · p75 593.2%
CapEx / revenue-0.0%-7.0% medp25 -14.9% · p75 -3.2%top quartile
Debt / equity38.0%25.0% medp25 3.8% · p75 63.3%above median
Observations
IR observations
Mean price target44.33 USD
Median price target48.00 USD
High price target60.00 USD
Low price target15.00 USD
Mean recommendation2.22 (1=strong buy, 5=strong sell)
Strong-buy count1.00
Buy count6.00
Hold count1.00
Sell count1.00
Strong-sell count0.00
Mean EPS estimate1.44 USD
Last actual EPS2.77 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-06 21:57 UTC#ab19e3b9
Source: analysis-pipeline (hybrid)Generated: 2026-05-29 17:04 UTCJob: ba2f40bd