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UNCY.O NASDAQ Pharmaceuticals & Medical Research

Unicycive Therapeutics Inc

$5,05
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Mcap
134,8M USD
P/E
EV / Rev
Div yield
Op margin
ROE
-87,9 %
Net margin
Debt / equity
0,00
Beta
52w range
Volume
6,3k
Day range
$6,99–$7,46
Prev close
$7,02
Open
$7,06
Next earnings
2026-10-28
Ex-dividend
TR 1Y
About

Unicycive Therapeutics Inc is a biotechnology company focused on the development and commercialization of innovative therapies for the treatment of neurological and psychiatric disorders.

Business. Unicycive Therapeutics Inc (UNCY.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding its operating segments and geographic revenue mix are not available.

Classification99 %
SectorHealth Care
Industry groupPharmaceuticals & Medical Research
Generated · model-assisted
Sell-side consensus
BUY8 analysts
8 buy0 hold0 sell
Avg 12m price target38,88

Analyst recommendations

8 analysts · consensus Buy
Buy8
Hold0
Sell0
12-month price target
38,88
Consensus of sell-side coverage.
Upcoming events
  • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
See all catalysts →

At a glance

Score
not yet scored
Valuation
valuation pending
Analysts
Buy
8 analysts · indicative
Ownership
Dimensional Fund Advisors, L.P.
largest disclosed fund holder
Profitability
-87,9 %
return on equity
Quality
not yet scored

What drives this business

The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.

— missing data

News & coverage

0
  • No recent newsroom coverage mentioning UNCY.
  • Sector rotation

    Sector1D1Mvs mkt
    Materials+2,3 %+6,6 %+1,7 %
    Communication Services+2,2 %−5,5 %+1,6 %
    Energy+0,6 %+3,3 %+0,0 %
    Health Care · THIS SECTOR+0,6 %−0,8 %+0,0 %
    Information Technology+0,6 %+6,7 %+0,0 %
    Consumer Discretionary+0,4 %+7,6 %−0,2 %
    Financials−0,3 %−2,8 %−0,9 %
    Consumer Staples−0,4 %+2,5 %−1,0 %
    Real Estate−0,7 %+10,9 %−1,3 %
    Industrials−1,9 %−3,1 %−2,5 %
    Utilities−1,9 %+28,2 %−2,5 %

    Developing storylines

    No tracked sagas currently linked to UNCY.O. Browse all sagas →

    Analysis

    AI analysis
    Generated · analysis pipeline · tier hybrid · as of 2026-08-04 ↑ At a glance

    Opportunity

    — missing data

    Upcoming catalysts

    Scheduled public events. Informational only — not investment advice.

    • Company
    • EarningsQ3 2026 earnings (expected)2026-10-28 · estimated
    • Macro
    • Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
    • Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
    • Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
    • Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
    • Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
    • Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
    • Macro & political
    • ElectionSE Swedish Election2026-09-14 · SE
    • ElectionUS U.S. Midterms2026-11-03 · US
    • ElectionFR French Legislative2027-06-01 · FR

    Pre-earnings brief

    — missing data

    Signals & dispatch

    peak dispatch · —

    Composite-score breakdown

    Synthesis

    Business

    Unicycive Therapeutics Inc (UNCY.O) is a biotechnology and medical research company operating within the healthcare sector. The firm is headquartered in the United States and is primarily listed on the NASDAQ stock exchange. Specific details regarding its operating segments and geographic revenue mix are not available.

    Classification99 %
    SectorHealth Care
    Industry groupPharmaceuticals & Medical Research
    AI synthesis
    GENERATED

    Unicycive Therapeutics Inc has a market capitalization of $219.74 million and a price-to-book ratio of 7.28, indicating that the market is valuing the company at a premium to its book value. The company has no long-term debt and a debt-to-equity ratio of 0.0, suggesting a conservative capital structure. The current ratio of 2.59 indicates that the company has sufficient current assets to cover its current liabilities.

    The company's profitability metrics are negative, with a return on equity of -87.94% and a return on assets of -54.04%. These figures indicate that the company is not generating returns for its shareholders and is underperforming in terms of asset utilization. The operating income and net income are both negative, at -$29.52 million and -$26.56 million, respectively, highlighting the company's current financial challenges.

    Unicycive Therapeutics Inc's revenue concentration and geographic exposure are not explicitly detailed in the available data. However, the company's operations are primarily focused on the development and commercialization of therapies for neurological and psychiatric disorders, which may involve a diverse set of markets and customer segments. The lack of detailed segment data limits the ability to assess specific revenue concentrations.

    The company's growth trajectory is uncertain, with no specific revenue growth projections provided. The operating cash flow is negative at -$31.32 million, and the free cash flow is also negative at -$26.55 million, indicating that the company is not generating positive cash flows from its operations. The capital expenditure is relatively low at -$24,000, suggesting minimal investment in new assets.

    The risk assessment for Unicycive Therapeutics Inc indicates low liquidity and dilution risks. There are no immediate filing-based liquidity or dilution flags detected. The company's dilution potential is low, and the custom valuations do not show any significant adjustments that would indicate a high risk of dilution.

    Recent events and filings for Unicycive Therapeutics Inc do not show any significant developments that would impact the company's financial position or strategic direction. The company's analyst estimates suggest a wide range of price targets, with a mean of $38.88 and a median of $31.00, indicating a high level of uncertainty among analysts regarding the company's future performance.

    Key takeaways
    • Unicycive Therapeutics Inc has a high price-to-book ratio of 7.28, indicating that the market is valuing the company at a premium to its book value.
    • The company is not generating returns for its shareholders, with a return on equity of -87.94% and a return on assets of -54.04%.
    • The company's operating income and net income are both negative, at -$29.52 million and -$26.56 million, respectively.
    • The company has no long-term debt and a debt-to-equity ratio of 0.0, suggesting a conservative capital structure.
    • The company's liquidity and dilution risks are low, with no immediate filing-based liquidity or dilution flags detected.
    • Analyst estimates for Unicycive Therapeutics Inc show a wide range of price targets, with a mean of $38.88 and a median of $31.00.

    Bull / Bear case

    Generated · model-assisted
    — missing data

    In focus — financials by report

    Valuation

    Market price
    $5,05
    Market cap
    $219.7M
    Enterprise value
    P/E
    Non-GAAP P/E
    EV / Revenue
    EV / Op income
    EV / OCF
    P / B
    7.3x
    P / Tangible book
    7.3x
    Tangible book
    $30.2M
    Net cash
    Current ratio
    2.6
    Debt / equity
    0.0
    ROA
    -54.0%
    ROE
    -87.9%
    Cash conversion
    118.0%
    CapEx / revenue
    SBC / revenue
    Dilution ratio
    0.0%

    Revenue by segment

    Market share

    INDUSTRYSEGMENTCOMPANYHealthcareIndustryPharmaceuticals & Medical Research15,2B node revenueKLAR 23,0%BNTX 21,4%EXEL 15,2%MDGL 6,3%INSM 4,0%VCYT 3,4%MDXG 2,8%AVIR 2,3%Other 21,6%
    Source: company disclosures · own-taxonomy revenue-covered setUNCY 0,0% · rank #77 of 109

    Business relationships

    Business relationships2 disclosed relationships · 1 type · extracted from filings & disclosures
    Customers2
    Davita IncDVA.OCustomer95%Source ↗
    Fresenius SE & Co. KGaAFRE.DECustomer95%Source ↗

    Supply chain

    Vendors → UNCY ↔ Partners → Customers · click any node to drill
    VENDORSPARTNERSCUSTOMERSUNCYUNCYUnicycive Therapeutics Inc2 entitiesDavita IncOil & Gas Exploration & USFresenius SE & Co. KGaDE
    2 mentions in 10-K0 from corporate websites0 from news dispatches
    Updated 2026-06-24

    Peer comparison

    Peer comparison8 peers · vs UNCY · multiples and returns
    KL
    KLAR
    KLAR.ST
    P/E
    vs self
    Div yield
    vs self
    ROE
    vs self
    BN
    BNTX
    Biontech SE
    $92,25
    23,3B USD
    P/E
    vs self
    Div yield
    vs self
    ROE
    vs self
    EX
    EXEL
    Exelixis Inc
    $55,06
    14,7B USD
    P/E
    19,5x
    vs self
    Div yield
    vs self
    ROE
    40,4 %
    +128,4 vs self
    MD
    MDGL
    Madrigal Pharmaceuticals Inc
    $482,00
    11,0B USD
    P/E
    vs self
    Div yield
    vs self
    ROE
    -47,8 %
    +40,1 vs self
    IN
    INSM
    Insmed Inc
    $107,46
    23,0B USD
    P/E
    vs self
    Div yield
    vs self
    ROE
    -160,2 %
    -72,3 vs self
    VC
    VCYT
    Veracyte Inc
    $45,30
    3,6B USD
    P/E
    55,5x
    vs self
    Div yield
    vs self
    ROE
    5,1 %
    +93,0 vs self
    MD
    MDXG
    Mimedx Group Inc
    $4,27
    636,0M USD
    P/E
    11,1x
    vs self
    Div yield
    vs self
    ROE
    18,9 %
    +106,9 vs self
    AV
    AVIR
    Atea Pharmaceuticals Inc
    $4,61
    P/E
    vs self
    Div yield
    vs self
    ROE
    -57,5 %
    +30,4 vs self

    Market position

    Stress test

    — missing data

    Predictor forecast

    Next quarternear-term
    Earnings · next quarterconf 45 %
    EPS
    Consensus EPS
    0,57
    Predicted surprise
    +0,00
    Beat probability
    45 %
    Analysts
    8
    Other metrics
    Revenue
    no estimate
    Segment revenue
    no estimate
    Margin
    no estimate
    Segment margin
    no estimate
    as of 2026-05-15 · Earnings Surprise V1
    Period note: consensus is not fiscal-period-aligned at source — read as consensus vs the last reported actual, not a calibrated same-quarter surprise.
    Full fiscal year~1 year ahead
    Full fiscal year · our forecast vs guidance vs consensus
    MetricOur forecastGuidanceConsensus
    EPSno estimateno estimate0,57
    Revenueno estimateno estimate56,0M USD
    Operating incomeno estimateno estimate4,0M USD
    Full-year consensus mean (period as reported by source) · consensus in USD. Company-level full-year forecast and management guidance are not yet modelled at scale — shown as "no estimate", never inferred.
    Probabilistic model output — not investment advice. · generated 2026-08-04

    Options

    — missing data

    Short squeeze

    — missing data

    Earnings-call key lines

    — missing data

    Consensus distribution

    sell-side coverage
    Recommendation distribution8 analysts
    Strong buy1
    Buy7
    Hold0
    Sell0
    Strong sell0
    12-month price target$38,88 · Median $31,00
    Low $15,00High $90,00
    Operating income · consensus4,0M USD
    EPS surprise
    −394,3 %
    reported vs consensus · miss
    Revenue surprise
    −100,0 %
    reported vs consensus · miss

    Estimate revisions

    consensus EPS · 26-week trend
    — missing data

    Sell-side observations

    Low$15,00
    Mean$38,88
    Median$31,00
    High$90,00
    Spot$5,05
    +669.8 %implied to mean12-month sell-side price targets · ▲ spot

    Themes

    — missing data

    ESG

    — missing data

    Risk factors

    Dilution riskLow
    Liquidity riskLow
    Filing-based flags
    • No immediate filing-based liquidity or dilution flags were detected.

    Benchmarks vs cohort

    ROE-87,9 %Bottom quartile
    D/E0,00Above median
    Cash Conv1,18Above median

    Corporate actions / M&A

    — missing data

    FX exposure

    — missing data

    Comparable transactions

    — missing data

    Derivatives & instruments

    Derivative transactions

    Net acquired 870 400 sh8 grants7 insiders
    • Laumas SandeepDirector · Restricted Stock Units → Common StockAcquired 84 200grant · 2026-05-14
    • Townsend JohnCFO · Restricted Stock Unit → Common StockAcquired 169 500grant · 2026-05-14
    • Gupta PramodEVP, Pharmaceuticals and BD · Restricted Stock Unit → Common StockAcquired 169 500grant · 2026-05-14
    • Jermasek DouglasEVP, Corporate Strategy · Restricted Stock Units → Common StockAcquired 169 500grant · 2026-05-14
    • Gupta Shalabh K.Director, CEO · Restricted Stock Units → Common StockAcquired 762 200grant · 2026-05-14
    • Kenkare-Mitra SaraDirector · Restricted Stock Units → Common StockAcquired 84 200grant · 2026-05-14
    • Kenkare-Mitra SaraDirector · Restricted Stock Units → Common StockAcquired 42 100grant · 2026-05-14
    • Laumas SandeepDirector · Restricted Stock Units → Common StockAcquired 42 100grant · 2026-05-14
    • Aggarwal GauravDirector · Series A-2 Prime Preferred Stock → Common StockDisposed 652 900 @ $4,90disposition · 2025-08-25

    Actions

    Ask Handelsavisen

    — missing data
    Data sources
    • Market data
    • Market data cache
    • Issuer disclosures
    • Public news
    • Earnings transcripts
    • Consensus estimates
    • ESG data
    How metrics are computed
    • Dilution Ratio
      (shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
    • Market Price
      input from market-data provider (delayed close or quote-shim mid)
    • Market Cap
      market_price * shares_outstanding_diluted
    • Return On Equity
      net_income / total_equity
    • Price To Tangible Book
      market_price / (tangible_book_value / shares_outstanding_diluted)
    • Debt To Equity
      (short_term_debt + long_term_debt) / total_equity
    Source documents
    • Unicycive Therapeutics Inc Market data — financials · 2026-05-29
    • Unicycive Therapeutics Inc Market data — analyst estimates · 2026-05-29

    Ownership & reference

    Top holders

    • Dimensional Fund Advisors, L.P.Investment Managers · as of 2026-03-310,00 %$1M
    • Geode Capital Management, L.L.C.Investment Managers · as of 2026-03-310,00 %$1M
    • Morgan Stanley Smith Barney LLCInvestment Managers · as of 2026-03-310,00 %$1M
    • Vanguard Capital Management, LLCInvestment Managers · as of 2025-12-310,00 %$5M
    • Northern Trust Investments, Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • Goldman Sachs Asset Management, L.P.Investment Managers · as of 2026-03-310,00 %$0M
    • UBS Financial Services, Inc.Investment Managers · as of 2026-03-310,00 %$0M
    • State Street Investment Management (US)Investment Managers · as of 2026-03-310,00 %$1M
    • BlackRock Institutional Trust Company, N.A.Investment Managers · as of 2024-06-300,00 %$0M

    Insider activity

    Mixed / flat0 buys · 0 sellsnet $01 insiders · last 365d
    • Aggarwal GauravDirector · Common StockOther 652 900 · 2025-08-25

    Short positioning

    4.9Mshares short+5.8% vs prior
    2.55days to cover
    32.7%short of daily vol
    188fails-to-deliver
    as of 2026-07-15 · short-interest report (free)

    Geographic breakdown

    — missing data
    Listings · one canonical issuer all listings resolve to the canonical
    UNCY.OCanonical
    NASDAQ · USD

    Intel & risk

    PredictorBeat prob45 %Surprise+0,00Full forecast →
    peak dispatch · —
    OSINT findings
    Dilution riskLow
    Liquidity riskLow
    No immediate filing-based liquidity or dilution flags were detected.
    Relationship graph
    UNCYDVA.OFRE.DEPharmaceutical
    This companySectorCustomers

    Evidence & claims

    From filings & derived data
    • Return on assets (FY 2025-12-31): -54.0%Derived (calculated)
    • Operating income (YoY) (2025-12-31 vs 2024-12-31): 8.1%Derived (calculated)
    • Debt-to-equity (FY 2025-12-31): 0.63xDerived (calculated)
    • Current ratio (FY 2025-12-31): 2.59xDerived (calculated)
    • Return on equity (FY 2025-12-31): -87.9%Derived (calculated)
    • Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -9.6%Derived (calculated)
    • R&D expense (YoY) (2025-12-31 vs 2024-12-31): -54.4%Derived (calculated)
    • Net income (YoY) (2025-12-31 vs 2024-12-31): 27.7%Derived (calculated)
    • EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 70.4%Derived (calculated)
    • EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 70.4%Derived (calculated)
    • Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): 306.4%Derived (calculated)
    • Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): 11.7%Derived (calculated)
    • Capex (YoY) (2025-12-31 vs 2024-12-31): -66.7%Derived (calculated)
    • Total assets (YoY) (2025-12-31 vs 2024-12-31): 55.2%Derived (calculated)
    • Total liabilities (YoY) (2025-12-31 vs 2024-12-31): -21.9%Derived (calculated)
    • Net income (annual): USD -26.55MSEC XBRL filing
    • Cash & equivalents (annual): USD 29.2MSEC XBRL filing
    • Shareholders' equity (annual): USD 30.2MSEC XBRL filing
    • Operating income (annual): USD -29.52MSEC XBRL filing
    • Capex (annual): USD 24KSEC XBRL filing
    • Current assets (annual): USD 48.96MSEC XBRL filing
    • Total liabilities (annual): USD 18.94MSEC XBRL filing
    • Total operating expenses (annual): USD 29.52MSEC XBRL filing
    • EPS (diluted) (annual): USD-PER-SHARES -2SEC XBRL filing
    Showing 24 of 60 surfaced claims.
    Atomic claims from regulatory filings and derived calculations. Provenance shown as source kind only.

    The Thread

    Everything we know, in order
    2026-10-28EVENTUpcomingQ3 2026 earnings (expected) estimated date
    2026-06-30 03:38 UTCEARNINGSUpcomingForecast: earnings_forecast (90d)
    2026-06-05FILINGCURRENT REPORT →
    2026-05-14 00:00 UTCINSIDER8 insider transactions — 2026-05 8 derivative
    2026-05-14INSIDERLaumas Sandeep acquired 84.2k sh Restricted Stock Units — Director
    2026-05-14INSIDERLaumas Sandeep acquired 42.1k sh Restricted Stock Units — Director
    2026-05-14INSIDERGupta Shalabh K. acquired 762.2k sh Restricted Stock Units — Director, CEO
    2026-05-14INSIDERTownsend John acquired 169.5k sh Restricted Stock Unit — CFO
    2026-05-14INSIDERGupta Pramod acquired 169.5k sh Restricted Stock Unit — EVP, Pharmaceuticals and BD
    2026-05-14INSIDERKenkare-Mitra Sara acquired 84.2k sh Restricted Stock Units — Director
    2026-05-14INSIDERKenkare-Mitra Sara acquired 42.1k sh Restricted Stock Units — Director
    2026-05-14INSIDERJermasek Douglas acquired 169.5k sh Restricted Stock Units — EVP, Corporate Strategy
    2026-05-12FILINGCURRENT REPORT →
    2026-05-12FILINGQUARTERLY REPORT →
    2026-04-06FILINGCURRENT REPORT →
    2026-03-30FILINGCURRENT REPORT →
    2026-03-30FILINGANNUAL REPORT →
    2025-11-14FILINGCURRENT REPORT →
    2025-11-12FILINGCURRENT REPORT →
    2025-11-12FILINGQUARTERLY REPORT →
    2025-10-28FILINGCURRENT REPORT →
    2025-08-25 00:00 UTCINSIDER2 insider transactions — 2025-08 1 derivative
    2025-08-25INSIDERAggarwal Gaurav transacted 652.9k sh — Director
    2025-08-25INSIDERAggarwal Gaurav disposed of 3.2k sh Series A-2 Prime Preferred Stock — Director
    2025-07-28 00:00 UTCINSIDER7 insider transactions — 2025-07 7 derivative
    2025-02-18 00:00 UTCINSIDER2 insider transactions — 2025-02 1 derivative
    2024-10-09 00:00 UTCINSIDER2 insider transactions — 2024-10 1 derivative
    2024-08-12 00:00 UTCINSIDER4 insider transactions — 2024-08 4 derivative
    2024-04-15 00:00 UTCINSIDER4 insider transactions — 2024-04 4 derivative
    2023-09-05 00:00 UTCINSIDER1 insider transaction — 2023-09 1 derivative
    The entity's full life in the product — typed, chronological, joined across Newspaper, Platform and Data. Our memory, made visible.
    Sources filings · IR · transcripts · market data · tier hybrid · as of 2026-08-04 Market data · Issuer disclosures · Public news · Earnings transcripts · Consensus estimates · ESG data Premium coverage