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INDICATIVE · SAMPLE DATA
XLO$7.7359

Xilio Therapeutics Inc

Biotechnology & Medical ResearchVerified

Xilio Therapeutics Inc maintains a strong liquidity position, with $137.53 million in cash and equivalents, representing 88.9% of its total assets. The company has no long-term debt, and its debt-to-equity ratio is 0.0, indicating a debt-free capital structure. The current ratio of 2.58 suggests the company has sufficient short-term assets to cover its short-term liabilities. However, the company reported negative operating cash flow of -$4.99 million and free cash flow of -$34.01 million, indicating ongoing cash burn despite its strong cash reserves. Profitability metrics show that Xilio is currently unprofitable, with a net loss of $35.04 million and an operating loss of $41.98 million. Return on equity (ROE) is -99.33%, and return on assets (ROA) is -22.65%, both significantly below the industry median for biotechnology firms. The company's price-to-book ratio of 1.31 and price-to-tangible-book ratio of 1.31 suggest that the market is valuing the company slightly above its book value, but the negative EBITDA and revenue multiples indicate a speculative valuation based on future expectations rather than current earnings. Xilio Therapeutics Inc operates as a single business segment, with all revenue derived from its biotechnology platform. The company does not disclose geographic revenue breakdowns, but its operations are primarily based in the United States. Given the lack of geographic diversification and the high concentration of revenue in a single therapeutic area, the company is exposed to significant business and regulatory risks. The company's growth trajectory is currently constrained by its negative operating performance. Revenue for the latest period was $43.77 million, but the company has not provided forward-looking revenue guidance. Analysts have assigned a mean price target of $20.00, significantly higher than the current market price of $7.73, suggesting strong expectations for future performance. However, the absence of disclosed revenue growth rates or segment-specific outlooks limits visibility into the drivers of this optimism. Risk factors include the company's reliance on external financing to fund operations, as well as the inherent risks associated with drug development, including clinical trial failures and regulatory delays. The risk assessment indicates low liquidity and dilution risk, but the company has not disclosed any specific dilution sources or near-term financing plans. The absence of long-term debt and the presence of $137.53 million in cash suggest that the company is not under immediate pressure to raise capital, but the negative cash flows indicate that this may change in the near future. Recent events include the publication of analyst price targets, with a mean recommendation of 1.00 (strong buy) and a high price target of $20.00. No recent filings or transcripts have been disclosed that provide additional insight into the company's strategic direction or financial performance. The lack of recent public commentary or disclosures may limit investor confidence in the company's transparency and operational progress.

30-day price · XLO-0.68 (-8.1%)
Low$7.40High$9.20Close$7.73As of13 May, 00:00 UTC
Profile
CompanyXilio Therapeutics Inc
TickerXLO.O
SectorHealthcare
BusinessPharmaceuticals & Medical Research
Industry groupPharmaceuticals & Medical Research
IndustryBiotechnology & Medical Research
AI analysis

Business. Xilio Therapeutics Inc is a biotechnology company focused on the development of novel therapeutics for the treatment of rare and serious diseases, primarily through its proprietary platform for the development of small molecule drugs.

Classification. Xilio Therapeutics Inc is classified under the Healthcare economic sector, within the Pharmaceuticals & Medical Research business sector, and the Biotechnology & Medical Research industry, with a classification confidence of 0.92.

Xilio Therapeutics Inc maintains a strong liquidity position, with $137.53 million in cash and equivalents, representing 88.9% of its total assets. The company has no long-term debt, and its debt-to-equity ratio is 0.0, indicating a debt-free capital structure. The current ratio of 2.58 suggests the company has sufficient short-term assets to cover its short-term liabilities. However, the company reported negative operating cash flow of -$4.99 million and free cash flow of -$34.01 million, indicating ongoing cash burn despite its strong cash reserves. Profitability metrics show that Xilio is currently unprofitable, with a net loss of $35.04 million and an operating loss of $41.98 million. Return on equity (ROE) is -99.33%, and return on assets (ROA) is -22.65%, both significantly below the industry median for biotechnology firms. The company's price-to-book ratio of 1.31 and price-to-tangible-book ratio of 1.31 suggest that the market is valuing the company slightly above its book value, but the negative EBITDA and revenue multiples indicate a speculative valuation based on future expectations rather than current earnings. Xilio Therapeutics Inc operates as a single business segment, with all revenue derived from its biotechnology platform. The company does not disclose geographic revenue breakdowns, but its operations are primarily based in the United States. Given the lack of geographic diversification and the high concentration of revenue in a single therapeutic area, the company is exposed to significant business and regulatory risks. The company's growth trajectory is currently constrained by its negative operating performance. Revenue for the latest period was $43.77 million, but the company has not provided forward-looking revenue guidance. Analysts have assigned a mean price target of $20.00, significantly higher than the current market price of $7.73, suggesting strong expectations for future performance. However, the absence of disclosed revenue growth rates or segment-specific outlooks limits visibility into the drivers of this optimism. Risk factors include the company's reliance on external financing to fund operations, as well as the inherent risks associated with drug development, including clinical trial failures and regulatory delays. The risk assessment indicates low liquidity and dilution risk, but the company has not disclosed any specific dilution sources or near-term financing plans. The absence of long-term debt and the presence of $137.53 million in cash suggest that the company is not under immediate pressure to raise capital, but the negative cash flows indicate that this may change in the near future. Recent events include the publication of analyst price targets, with a mean recommendation of 1.00 (strong buy) and a high price target of $20.00. No recent filings or transcripts have been disclosed that provide additional insight into the company's strategic direction or financial performance. The lack of recent public commentary or disclosures may limit investor confidence in the company's transparency and operational progress.
Key takeaways
  • Xilio Therapeutics Inc is a biotechnology company with a debt-free capital structure and strong liquidity, but it is currently unprofitable with negative operating and free cash flows.
  • The company's valuation is speculative, with a price-to-book ratio of 1.31 and a negative EBITDA multiple, reflecting high expectations for future performance.
  • Xilio operates as a single business segment with no geographic diversification, exposing it to significant business and regulatory risks.
  • Analysts have assigned a strong buy rating with a mean price target of $20.00, but the company has not provided forward-looking revenue guidance or segment-specific outlooks.
  • The company is not under immediate liquidity or dilution pressure, but its negative cash flows suggest that it may need to raise capital in the near future.
  • --
  • ## RATIONALES
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Financial snapshot
PeriodHA-latest
CurrencyUSD
Revenue$43.8M
Gross profit
Operating income-$42.0M
Net income-$35.0M
R&D
SG&A
D&A
SBC
Operating cash flow-$5.0M
CapEx-$518.0k
Free cash flow-$34.0M
Total assets$154.7M
Total liabilities$119.4M
Total equity$35.3M
Cash & equivalents$137.5M
Long-term debt$0.00
Annual history (last 5)
PeriodRevenueOp IncomeNet IncomeFCF
FY0$43.8M-$42.0M-$35.0M-$34.0M
FY-1$6.3M-$60.6M-$58.2M-$56.6M
FY-2-$79.1M-$76.4M-$75.0M
FY-3
FY-4
PeriodGross %Op %Net %FCF %
FY0
FY-1
FY-2
FY-3
FY-4
PeriodAssetsEquityCashDebt
FY0$154.7M$35.3M$137.5M
FY-1$71.1M$17.6M$55.3M
FY-2$60.9M$36.8M$44.7M
FY-3
FY-4
PeriodOCFCapExFCFSBC
FY0-$5.0M-$518.0k-$34.0M
FY-1-$18.4M-$36.0k-$56.6M
FY-2-$68.6M-$486.0k-$75.0M
FY-3
FY-4
Quarterly history (last 4)
PeriodRevenueOp IncomeNet IncomeFCF
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodGross %Op %Net %FCF %
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodAssetsEquityCashDebt
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
PeriodOCFCapExFCFSBC
FQ0
FQ-1
FQ-2
FQ-3
FQ-4
FQ-5
FQ-6
FQ-7
Valuation
Market price$7.73
Market cap$46.2M
Enterprise value-$91.3M
P/E
Reported non-GAAP P/E
EV/Revenue-2.1
EV/Op income
EV/OCF
P/B1.3
P/Tangible book1.3
Tangible book$35.3M
Net cash$137.5M
Current ratio2.6
Debt/Equity0.0
ROA-22.7%
ROE-99.3%
Cash conversion14.0%
CapEx/Revenue-1.2%
SBC/Revenue
Asset intensity
Dilution ratio0.0%
Risk assessment
Dilution riskLow
Liquidity riskLow
  • No immediate filing-based liquidity or dilution flags were detected.
Industry benchmarks
Activity: Healthcare Diagnostics · cohort 254 companies
MetricXLOActivity
Op margin-95.9%7.0% medp25 3.8% · p75 10.2%bottom quartile
Net margin-80.1%2.4% medp25 -0.6% · p75 5.4%bottom quartile
Gross margin50.1% medp25 23.6% · p75 72.3%
CapEx / revenue-1.2%-6.8% medp25 -27.8% · p75 -1.7%top quartile
Debt / equity0.0%140.5% medp25 104.0% · p75 177.0%bottom quartile
Observations
IR observations
Mean price target20.00 USD
Median price target20.00 USD
High price target20.00 USD
Low price target20.00 USD
Mean recommendation1.00 (1=strong buy, 5=strong sell)
Strong-buy count1.00
Buy count0.00
Hold count0.00
Sell count0.00
Strong-sell count0.00
Mean EPS estimate-2.39 USD
Last actual EPS-4.19 USD
Source data
Underlying data the analysis-pipeline pulls and audits. Fetch timestamps + content hashes show when each source was last refreshed.
Company fundamentalsperiod FQ-7 · history via verified-market-data
no public URL
2026-05-16 17:02 UTC#2331c505
Market quoteclose USD 7.73 · shares 0.01B diluted
no public URL
2026-05-16 17:02 UTC#d68a319d
Source: analysis-pipeline (hybrid)Generated: 2026-05-16 17:04 UTCJob: 510703f1