Sera Prognostics Inc
Sera Prognostics Inc develops and commercializes diagnostic tests for women's health, primarily focused on predicting preterm birth risk using proprietary biomarker technology.
Business. Sera Prognostics Inc (SERA.O) is a business support services company operating within the Industrial & Commercial Services sector. The firm generates service revenue through industrial services activities. Headquarters and specific operating segment details are not provided in the available data. The company is listed on the NASDAQ stock exchange.
Analyst recommendations
3 analysts · consensus BuyAt a glance
What drives this business
The watch-list the newsroom runs for this company — derived from its sector path, sharpened layer by layer. Not investment advice.
News & coverage
0Sector rotation
Developing storylines
Analysis
AI analysisOpportunity
Upcoming catalysts
Scheduled public events. Informational only — not investment advice.
- Macro
- Rate decisionBank of England rate decision (press conf.)2026-08-06 · GB
- Rate decisionReserve Bank of Australia rate decision (press conf.)2026-08-12 · AU
- Rate decisionNorges Bank rate decision (press conf.)2026-08-20 · NO
- Rate decisionSveriges Riksbank rate decision (press conf.)2026-09-03 · SE
- Rate decisionBank of Canada rate decision (press conf.)2026-09-09 · CA
- Rate decisionEuropean Central Bank rate decision (press conf.)2026-09-10 · EU
- Macro & political
- ElectionSE Swedish Election2026-09-14 · SE
- ElectionUS U.S. Midterms2026-11-03 · US
- ElectionFR French Legislative2027-06-01 · FR
Pre-earnings brief
Signals & dispatch
Composite-score breakdown
Synthesis
Sera Prognostics Inc (SERA.O) is a business support services company operating within the Industrial & Commercial Services sector. The firm generates service revenue through industrial services activities. Headquarters and specific operating segment details are not provided in the available data. The company is listed on the NASDAQ stock exchange.
Sera Prognostics operates with a highly leveraged equity structure, as evidenced by a price-to-book ratio of 0.93 and a tangible book ratio of 0.93, indicating the market values the company at a discount to its net asset value. The company's liquidity position is weak, with a cash balance of $3.94 million and negative operating cash flow of $25.62 million, suggesting reliance on external financing to fund operations. The current ratio of 1.69 indicates the company can cover its short-term liabilities, but the absence of long-term debt ($2,000) and a debt-to-equity ratio of 0.0 suggest minimal leverage in its capital structure.
Profitability metrics are deeply negative, with a return on equity of -42.34% and a return on assets of -31.32%, far below industry benchmarks. The company reported a net loss of $31.93 million on $81.00 million in revenue, with a gross profit of -$83.00 million, indicating significant cost overruns or pricing pressures. The operating margin is -450.67%, and the company's EBITDA multiple is -1.81, reflecting a lack of operating leverage and poor cost control.
Geographically, Sera Prognostics does not disclose segment or geographic revenue breakdowns in the provided data, making it difficult to assess exposure to specific markets. However, the company's primary product, the PreMSafe test, is marketed in the U.S., suggesting a concentration risk in domestic healthcare reimbursement policies and regulatory environments.
The company's growth trajectory is constrained by its financial performance, with no revenue growth data provided and a negative free cash flow of $31.71 million. Analysts have assigned a mean price target of $5.00, implying a potential 179% upside from the current market price of $1.79, but this is based on limited data and a small sample of 3 analysts (2 strong buy, 1 buy). The absence of capex and R&D spending details in the financial snapshot makes it difficult to assess long-term innovation potential.
Risk factors include liquidity constraints, with a low liquidity risk score and no immediate filing-based flags, but the company's negative operating cash flow and low cash reserves suggest a high dependency on external financing. The dilution risk is currently low, with no near-term pressure identified, but the company's equity valuation at a discount to book value may incentivize future share issuance. No recent filings or transcripts are provided to assess management commentary or strategic shifts.
The company's valuation is highly speculative, with an EV-to-revenue multiple of 816.69, far exceeding industry norms. This suggests the market is pricing in significant future revenue growth or regulatory approval milestones, which are not yet reflected in current financials. The absence of long-term debt and a current ratio above 1.5 provide some near-term solvency comfort, but the company's negative net income and operating cash flow indicate a need for continued capital infusions.
- Sera Prognostics is a high-risk, high-reward biotech diagnostic company with a speculative valuation and no current profitability.
- The company's liquidity position is weak, with negative operating cash flow and limited cash reserves.
- Analysts are optimistic about the stock, but the price target is based on a small sample and assumes significant future growth.
- The company's valuation is driven by potential regulatory approvals and market adoption of its PreMSafe test, not current financial performance.
- No immediate dilution or liquidity risks are flagged, but the company's equity valuation at a discount to book value may lead to future share issuance.
Bull / Bear case
Generated · model-assistedIn focus — financials by report
Valuation
Revenue by segment
Business relationships
Supply chain
Peer comparison
Market position
Stress test
Predictor forecast
| Metric | Our forecast | Guidance | Consensus |
|---|---|---|---|
| EPS | —no estimate | —no estimate | -0,67 |
| Revenue | —no estimate | —no estimate | 520,000 USD |
| Operating income | —no estimate | —no estimate | -35,2M USD |
Options
Short squeeze
Earnings-call key lines
Consensus distribution
sell-side coverageEstimate revisions
consensus EPS · 26-week trendSell-side observations
Themes
ESG
Risk factors
- No immediate filing-based liquidity or dilution flags were detected.
Benchmarks vs cohort
Corporate actions / M&A
FX exposure
Comparable transactions
Derivatives & instruments
Derivative transactions
- General Counsel · Stock Option (right to buy) → Class A Common StockAcquired 68 550 @ $1,99grant · 2026-03-12
- Chief Financial Officer · Stock Option (right to buy) → Class A Common StockAcquired 68 550 @ $1,99grant · 2026-03-12
- Chief Commercial Officer · Stock Option (right to buy) → Class A Common StockAcquired 19 310 @ $1,99grant · 2026-03-12
- Chief Medical Officer · Stock Option (right to buy) → Class A Common StockAcquired 27 034 @ $1,99grant · 2026-03-12
- Director, Chief Executive Officer · Stock Option (right to buy) → Class A Common StockAcquired 239 442 @ $1,99grant · 2026-03-12
Actions
Ask Handelsavisen
- Market data
- Market data cache
- Issuer disclosures
- Public news
- Earnings transcripts
- Consensus estimates
- ESG data
- Return On Equitynet_income / total_equity
- Price To Bookmarket_price / (adjusted_book_value / shares_outstanding_diluted)
- Dilution Ratio(shares_outstanding_diluted - shares_outstanding_basic) / shares_outstanding_basic
- Market Priceinput from market-data provider (delayed close or quote-shim mid)
- Market Capmarket_price * shares_outstanding_diluted
- Ev To Revenueenterprise_value / revenue
- Sera Prognostics Inc Market data — financials · 2026-05-29
- Sera Prognostics Inc Market data — analyst estimates · 2026-05-29
- Sera Prognostics Inc Market data — ESG · 2026-05-29
Ownership & reference
Top holders
- Investment Managers · as of 2024-06-300,00 %$8M
- Investment Managers · as of 2024-12-310,00 %$0M
- Investment Managers · as of 2025-12-310,00 %$4M
- Investment Managers · as of 2026-03-310,00 %$1M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Investment Managers · as of 2026-03-310,00 %$0M
- Institutional Investor · as of 2026-03-310,00 %$0M
Insider activity
- General Counsel · Class A Common StockSold 2 179 @ $2,01$4K · 2026-06-11
- Chief Commercial Officer · Class A Common StockSold 4 739 @ $2,01$10K · 2026-06-11
- Chief Financial Officer · Class A Common StockSold 2 037 @ $2,01$4K · 2026-06-11
- Director, Chief Executive Officer · Class A Common StockSold 6 990 @ $2,01$14K · 2026-06-11
- Chief Medical Officer · Class A Common StockSold 362 @ $2,01$728 · 2026-06-11
- Director, Chief Executive Officer · Class A Common StockSold 20 755 @ $2,08$43K · 2026-06-09
- Chief Financial Officer · Class A Common StockSold 5 440 @ $2,08$11K · 2026-06-09
- Director · Class A Common StockSold 1 560 @ $2,15$3K · 2026-06-08
- Chief Commercial Officer · Class A Common StockOther 3 168 @ $1,84$6K · 2026-05-29
- General Counsel · Class A Common StockOther 5 000 @ $1,84$9K · 2026-05-29
- Chief Commercial Officer · Class A Common StockOther 12 455 · 2026-03-12
- Director, Chief Executive Officer · Class A Common StockOther 154 440 · 2026-03-12
- General Counsel · Class A Common StockOther 44 215 · 2026-03-12
- Chief Medical Officer · Class A Common StockOther 17 437 · 2026-03-12
- Chief Financial Officer · Class A Common StockOther 44 215 · 2026-03-12
- Chief Financial Officer · Class A Common StockSold 1 019 @ $2,04$2K · 2026-03-11
- General Counsel · Class A Common StockSold 1 027 @ $2,04$2K · 2026-03-11
- Chief Information Officer · Class A Common StockSold 716 @ $2,04$1K · 2026-03-11
- Chief Scientific Officer · Class A Common StockSold 1 517 @ $2,04$3K · 2026-03-11
- Director, Chief Executive Officer · Class A Common StockSold 2 973 @ $2,04$6K · 2026-03-11
- Chief Data Officer · Class A Common StockSold 1 396 @ $2,04$3K · 2026-03-11
- Director, Chief Executive Officer · Class A Common StockSold 22 639 @ $1,90$43K · 2026-03-10
- Chief Financial Officer · Class A Common StockSold 6 069 @ $1,90$12K · 2026-03-10
Short positioning
Geographic breakdown
Intel & risk
Evidence & claims
From filings & derived data- EPS (basic) (YoY) (2025-12-31 vs 2024-12-31): 32.3%Derived (calculated)
- Net margin (FY 2025-12-31): -39,417.3%Derived (calculated)
- Return on equity (FY 2025-12-31): -42.3%Derived (calculated)
- Return on assets (FY 2025-12-31): -31.3%Derived (calculated)
- Current ratio (FY 2025-12-31): 1.69xDerived (calculated)
- Debt-to-equity (FY 2025-12-31): 0.35xDerived (calculated)
- Capex (YoY) (2025-12-31 vs 2024-12-31): 1,196.4%Derived (calculated)
- Cash & equivalents (YoY) (2025-12-31 vs 2024-12-31): -2.4%Derived (calculated)
- EPS (diluted) (YoY) (2025-12-31 vs 2024-12-31): 32.3%Derived (calculated)
- Net income (YoY) (2025-12-31 vs 2024-12-31): 2.9%Derived (calculated)
- Operating cash flow (YoY) (2025-12-31 vs 2024-12-31): -80.6%Derived (calculated)
- Operating income (YoY) (2025-12-31 vs 2024-12-31): 0.4%Derived (calculated)
- R&D expense (YoY) (2025-12-31 vs 2024-12-31): -10.6%Derived (calculated)
- Revenue (YoY) (2025-12-31 vs 2024-12-31): 5.2%Derived (calculated)
- Shareholders' equity (YoY) (2025-12-31 vs 2024-12-31): 57.7%Derived (calculated)
- Total assets (YoY) (2025-12-31 vs 2024-12-31): 40.5%Derived (calculated)
- Total liabilities (YoY) (2025-12-31 vs 2024-12-31): 7.1%Derived (calculated)
- Cost of revenue (YoY) (2025-12-31 vs 2024-12-31): 100.0%Derived (calculated)
- Total operating expenses (annual): USD 36.59MSEC XBRL filing
- Pre-tax income (annual): USD -31.93MSEC XBRL filing
- EPS (diluted) (annual): USD-PER-SHARES -1SEC XBRL filing
- Cost of revenue (annual): USD 164KSEC XBRL filing
- Total liabilities (annual): USD 26.52MSEC XBRL filing
- Cash & equivalents (annual): USD 3.94MSEC XBRL filing